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Items: 1 to 50 of 274

1.

Alemtuzumab in combination with methylprednisolone is a highly effective induction regimen for patients with chronic lymphocytic leukemia and deletion of TP53: final results of the national cancer research institute CLL206 trial.

Pettitt AR, Jackson R, Carruthers S, Dodd J, Dodd S, Oates M, Johnson GG, Schuh A, Matutes E, Dearden CE, Catovsky D, Radford JA, Bloor A, Follows GA, Devereux S, Kruger A, Blundell J, Agrawal S, Allsup D, Proctor S, Heartin E, Oscier D, Hamblin TJ, Rawstron A, Hillmen P.

J Clin Oncol. 2012 May 10;30(14):1647-55. doi: 10.1200/JCO.2011.35.9695. Epub 2012 Apr 9.

PMID:
22493413
2.

Searching for surrogates for IGHV mutations in chronic lymphocytic leukemia.

Hamblin TJ.

Leuk Res. 2011 Nov;35(11):1432-5. doi: 10.1016/j.leukres.2011.07.020. Epub 2011 Aug 12. Review.

PMID:
21840049
3.

The Myelodysplastic Syndromes (MDS) Foundation: a retrospective analysis of a nonprofit foundation.

Bennett JM, Hamblin TJ, Mufti GJ.

Leuk Res. 2011 Mar;35(3):283-5. doi: 10.1016/j.leukres.2010.09.023. Epub 2010 Oct 23. No abstract available.

PMID:
20971510
4.

Childhood obesity and low-velocity knee dislocation in a fifteen-year-old girl: a case report.

Hamblin T, Curtis SH, D'Astous J, Aoki SK.

J Bone Joint Surg Am. 2010 Sep 15;92(12):2216-9. doi: 10.2106/JBJS.J.00115. No abstract available.

PMID:
20844165
5.

In vitro response of the natural cadaver knee to the loading profiles specified in a standard for knee implant wear testing.

Sutton LG, Werner FW, Haider H, Hamblin T, Clabeaux JJ.

J Biomech. 2010 Aug 10;43(11):2203-7. doi: 10.1016/j.jbiomech.2010.03.042. Epub 2010 May 7.

PMID:
20451913
6.

The TCL1 mouse as a model for chronic lymphocytic leukemia.

Hamblin TJ.

Leuk Res. 2010 Feb;34(2):135-6. doi: 10.1016/j.leukres.2009.08.004. Epub 2009 Sep 1. Review.

PMID:
19726084
7.

Just exactly how common is CLL?

Hamblin TJ.

Leuk Res. 2009 Nov;33(11):1452-3. doi: 10.1016/j.leukres.2009.07.005. Epub 2009 Jul 26. No abstract available.

PMID:
19632721
8.

IgA anti-epidermal transglutaminase antibodies in dermatitis herpetiformis and pediatric celiac disease.

Jaskowski TD, Hamblin T, Wilson AR, Hill HR, Book LS, Meyer LJ, Zone JJ, Hull CM.

J Invest Dermatol. 2009 Nov;129(11):2728-30. doi: 10.1038/jid.2009.142. Epub 2009 Jun 11. No abstract available.

9.

Fludarabine, cyclophosphamide and rituximab for chronic lymphocytic leukemia: no country for old men?

Hamblin TJ.

Nat Clin Pract Oncol. 2009 Mar;6(3):130-1. doi: 10.1038/ncponc1318. Epub 2009 Jan 20.

PMID:
19153569
10.

Complementary medicine . Inconsistency over payment.

Hamblin TJ.

BMJ. 2008 Nov 3;337:a2388. doi: 10.1136/bmj.a2388. No abstract available.

PMID:
18981024
11.

Non-hemic autoimmunity in CLL.

Hamblin TJ.

Leuk Res. 2009 Mar;33(3):366-7. doi: 10.1016/j.leukres.2008.09.011. Epub 2008 Oct 18.

PMID:
18930543
12.

The immunodeficiency of chronic lymphocytic leukaemia.

Hamblin AD, Hamblin TJ.

Br Med Bull. 2008;87:49-62. doi: 10.1093/bmb/ldn034. Epub 2008 Aug 27. Review.

PMID:
18755702
13.

Ligandless receptors find a role.

Hamblin TJ.

Blood. 2008 Jul 1;112(1):2-3. doi: 10.1182/blood-2008-03-144113. No abstract available.

14.

Chronic lymphocytic leukaemia.

Dighiero G, Hamblin TJ.

Lancet. 2008 Mar 22;371(9617):1017-29. doi: 10.1016/S0140-6736(08)60456-0. Review.

PMID:
18358929
15.

CD38 expression in chronic lymphocytic leukemia is regulated by the tumor microenvironment.

Patten PE, Buggins AG, Richards J, Wotherspoon A, Salisbury J, Mufti GJ, Hamblin TJ, Devereux S.

Blood. 2008 May 15;111(10):5173-81. doi: 10.1182/blood-2007-08-108605. Epub 2008 Mar 7.

16.

Approaches to therapy for children in India with cerebral palsy.

Hamblin T, Kaul S, Dalvi UA.

J Pediatr Rehabil Med. 2008;1(2):169-74.

PMID:
21791761
17.

The prognostic significance of a positive direct antiglobulin test in chronic lymphocytic leukemia: a beneficial effect of the combination of fludarabine and cyclophosphamide on the incidence of hemolytic anemia.

Dearden C, Wade R, Else M, Richards S, Milligan D, Hamblin T, Catovsky D; UK National Cancer Research Institute (NCRI); Haematological Oncology Clinical Studies Group; NCRI CLL Working Group.

Blood. 2008 Feb 15;111(4):1820-6. Epub 2007 Nov 30.

19.

Have we been wrong about ionizing radiation and chronic lymphocytic leukemia?

Hamblin TJ.

Leuk Res. 2008 Apr;32(4):523-5. Epub 2007 Oct 29.

PMID:
17915317
20.

Prognostic markers in chronic lymphocytic leukaemia.

Hamblin TJ.

Best Pract Res Clin Haematol. 2007 Sep;20(3):455-68. Review.

PMID:
17707833
21.

Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 Trial): a randomised controlled trial.

Catovsky D, Richards S, Matutes E, Oscier D, Dyer M, Bezares RF, Pettitt AR, Hamblin T, Milligan DW, Child JA, Hamilton MS, Dearden CE, Smith AG, Bosanquet AG, Davis Z, Brito-Babapulle V, Else M, Wade R, Hillmen P; UK National Cancer Research Institute (NCRI) Haematological Oncology Clinical Studies Group; NCRI Chronic Lymphocytic Leukaemia Working Group.

Lancet. 2007 Jul 21;370(9583):230-239. doi: 10.1016/S0140-6736(07)61125-8.

PMID:
17658394
22.

Myocardial iron loading by magnetic resonance imaging T2* in good prognostic myelodysplastic syndrome patients on long-term blood transfusions.

Chacko J, Pennell DJ, Tanner MA, Hamblin TJ, Wonke B, Levy T, Thomas PW, Killick SB.

Br J Haematol. 2007 Sep;138(5):587-93. Epub 2007 Jul 4.

PMID:
17610536
23.

ZAP-70 levels do change in CLL but not very often.

Hamblin TJ.

Leuk Lymphoma. 2007 Jun;48(6):1059-60. No abstract available.

PMID:
17577764
24.

Prognostic factors in chronic lymphocytic leukemia.

Hamblin T.

Leuk Lymphoma. 2006 Nov;47(11):2261-2. No abstract available.

PMID:
17107890
25.

Open forum--Are myelodysplastic syndromes cancer? Response to Dr. Steensma.

Hamblin T.

Leuk Res. 2007 Mar;31(3):412-3. Epub 2006 Sep 28. No abstract available.

PMID:
17010432
27.

Is "leukemia" an appropriate label for all patients who meet the diagnostic criteria of chronic lymphocytic leukemia?

Victor Hoffbrand A, Hamblin TJ.

Leuk Res. 2007 Mar;31(3):273-5. Epub 2006 Aug 22. Review.

PMID:
16930694
28.

Autoimmune complications of chronic lymphocytic leukemia.

Hamblin TJ.

Semin Oncol. 2006 Apr;33(2):230-9. Review.

PMID:
16616070
29.

Is chronic lymphocytic leukemia a response to infectious agents?

Hamblin T.

Leuk Res. 2006 Sep;30(9):1063-4. Epub 2006 Jan 6. No abstract available.

PMID:
16406017
30.

Natural products and the treatment of leukemia.

Hamblin T.

Leuk Res. 2006 Jun;30(6):649-50. Epub 2005 Dec 6.

PMID:
16337269
31.

Chronic lymphocytic leukaemia: clinical translations of biological features.

Hamblin TJ.

Curr Top Microbiol Immunol. 2005;294:165-85. Review.

PMID:
16323432
32.

Functional and prognostic role of ZAP-70 in chronic lymphocytic leukaemia.

Hamblin AD, Hamblin TJ.

Expert Opin Ther Targets. 2005 Dec;9(6):1165-78. Review.

PMID:
16300468
33.

Determining the degree of cortical bone asymmetry in bilateral, nonpathological, human femur pairs.

Rosenbaum TG, Hamblin T, Bloebaum RD.

J Biomed Mater Res A. 2006 Mar 1;76(3):450-5.

PMID:
16270336
34.

Differential expression of CD 180 and IgM by B-cell chronic lymphocytic leukaemia cells using mutated and unmutated immunoglobulin VH genes.

Porakishvili N, Kulikova N, Jewell AP, Youinou PY, Yong K, Nathwani A, Heelan B, Duke V, Hamblin TJ, Wallace P, Ely P, Clark EA, Lydyard PM.

Br J Haematol. 2005 Nov;131(3):313-9.

PMID:
16225650
35.

Richter's syndrome--the downside of fludarabine?

Hamblin TJ.

Leuk Res. 2005 Oct;29(10):1103-4. Epub 2005 Apr 9. No abstract available.

PMID:
16111529
36.

The management of anemia in the myelodysplastic syndrome.

Hamblin TJ.

Leuk Res. 2005 Oct;29(10):1101-2. Epub 2005 Apr 9.

PMID:
16111528
37.

Chronic lymphocytic leukemia: novel prognostic factors and their relevance for risk-adapted therapeutic strategies.

Montillo M, Hamblin T, Hallek M, Montserrat E, Morra E.

Haematologica. 2005 Mar;90(3):391-9. Review.

38.

Predicting Progression--ZAP-70 in CLL.

Hamblin TJ.

N Engl J Med. 2004 Aug 26;351(9):856-7. No abstract available.

PMID:
15329421
39.

Common patterns of B cell perturbation and expanded V4-34 immunoglobulin gene usage in autoimmunity and infection.

Mockridge CI, Rahman A, Buchan S, Hamblin T, Isenberg DA, Stevenson FK, Potter KN.

Autoimmunity. 2004 Feb;37(1):9-15.

PMID:
15115306
40.

ZAP-70 expression and prognosis in chronic lymphocytic leukaemia.

Orchard JA, Ibbotson RE, Davis Z, Wiestner A, Rosenwald A, Thomas PW, Hamblin TJ, Staudt LM, Oscier DG.

Lancet. 2004 Jan 10;363(9403):105-11.

PMID:
14726163
41.

Anti-idiotype vaccines.

McCarthy H, Ottensmeier CH, Hamblin TJ, Stevenson FK.

Br J Haematol. 2003 Dec;123(5):770-81. Review. No abstract available.

PMID:
14632768
42.

Adaptor protein 3-dependent microtubule-mediated movement of lytic granules to the immunological synapse.

Clark RH, Stinchcombe JC, Day A, Blott E, Booth S, Bossi G, Hamblin T, Davies EG, Griffiths GM.

Nat Immunol. 2003 Nov;4(11):1111-20. Epub 2003 Oct 19.

PMID:
14566336
43.

ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile.

Wiestner A, Rosenwald A, Barry TS, Wright G, Davis RE, Henrickson SE, Zhao H, Ibbotson RE, Orchard JA, Davis Z, Stetler-Stevenson M, Raffeld M, Arthur DC, Marti GE, Wilson WH, Hamblin TJ, Oscier DG, Staudt LM.

Blood. 2003 Jun 15;101(12):4944-51. Epub 2003 Feb 20.

44.

Disturbances in peripheral blood B cell subpopulations in autoimmune patients.

Potter KN, Mockridge CI, Rahman A, Buchan S, Hamblin T, Davidson B, Isenberg DA, Stevenson FK.

Lupus. 2002;11(12):872-7. Review.

PMID:
12529053
45.

Is chronic lymphocytic leukemia one disease?

Hamblin T.

Haematologica. 2002 Dec;87(12):1235-8. No abstract available.

46.

Chronic lymphocytic leukemia.

Kay NE, Hamblin TJ, Jelinek DF, Dewald GW, Byrd JC, Farag S, Lucas M, Lin T.

Hematology Am Soc Hematol Educ Program. 2002:193-213. Review.

PMID:
12446424
47.

Differential signaling via surface IgM is associated with VH gene mutational status and CD38 expression in chronic lymphocytic leukemia.

Lanham S, Hamblin T, Oscier D, Ibbotson R, Stevenson F, Packham G.

Blood. 2003 Feb 1;101(3):1087-93. Epub 2002 Sep 26.

48.

The alternative transcript of CD79b is overexpressed in B-CLL and inhibits signaling for apoptosis.

Cragg MS, Chan HT, Fox MD, Tutt A, Smith A, Oscier DG, Hamblin TJ, Glennie MJ.

Blood. 2002 Nov 1;100(9):3068-76.

49.

Typical Waldenstrom macroglobulinemia is derived from a B-cell arrested after cessation of somatic mutation but prior to isotype switch events.

Sahota SS, Forconi F, Ottensmeier CH, Provan D, Oscier DG, Hamblin TJ, Stevenson FK.

Blood. 2002 Aug 15;100(4):1505-7.

50.

Multivariate analysis of prognostic factors in CLL: clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors.

Oscier DG, Gardiner AC, Mould SJ, Glide S, Davis ZA, Ibbotson RE, Corcoran MM, Chapman RM, Thomas PW, Copplestone JA, Orchard JA, Hamblin TJ.

Blood. 2002 Aug 15;100(4):1177-84.

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