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Items: 1 to 50 of 308

1.

Plant hydroperoxide-cleaving enzymes (CYP74 family) function as hemiacetal synthases: Structural proof of hemiacetals by NMR spectroscopy.

Mukhtarova LS, Brühlmann F, Hamberg M, Khairutdinov BI, Grechkin AN.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Oct;1863(10):1316-1322. doi: 10.1016/j.bbalip.2018.08.011. Epub 2018 Aug 20.

PMID:
30305246
2.

An LC-MS/MS workflow to characterize 16 regio- and stereoisomeric trihydroxyoctadecenoic acids.

Fuchs D, Hamberg M, Sköld CM, Wheelock ÅM, Wheelock CE.

J Lipid Res. 2018 Oct;59(10):2025-2033. doi: 10.1194/jlr.D087429. Epub 2018 Jul 31.

PMID:
30065010
3.

Prominent release of lipoxygenase generated mediators in a murine house dust mite-induced asthma model.

Kolmert J, Piñeiro-Hermida S, Hamberg M, Gregory JA, López IP, Fauland A, Wheelock CE, Dahlén SE, Pichel JG, Adner M.

Prostaglandins Other Lipid Mediat. 2018 Jul;137:20-29. doi: 10.1016/j.prostaglandins.2018.05.005. Epub 2018 May 12.

PMID:
29763661
4.

Ligand-receptor co-evolution shaped the jasmonate pathway in land plants.

Monte I, Ishida S, Zamarreño AM, Hamberg M, Franco-Zorrilla JM, García-Casado G, Gouhier-Darimont C, Reymond P, Takahashi K, García-Mina JM, Nishihama R, Kohchi T, Solano R.

Nat Chem Biol. 2018 May;14(5):480-488. doi: 10.1038/s41589-018-0033-4. Epub 2018 Apr 9.

PMID:
29632411
5.

Arabidopsis nonresponding to oxylipins locus NOXY7 encodes a yeast GCN1 homolog that mediates noncanonical translation regulation and stress adaptation.

Izquierdo Y, Kulasekaran S, Benito P, López B, Marcos R, Cascón T, Hamberg M, Castresana C.

Plant Cell Environ. 2018 Jun;41(6):1438-1452. doi: 10.1111/pce.13182. Epub 2018 Mar 30.

PMID:
29499090
6.

An OPR3-independent pathway uses 4,5-didehydrojasmonate for jasmonate synthesis.

Chini A, Monte I, Zamarreño AM, Hamberg M, Lassueur S, Reymond P, Weiss S, Stintzi A, Schaller A, Porzel A, García-Mina JM, Solano R.

Nat Chem Biol. 2018 Feb;14(2):171-178. doi: 10.1038/nchembio.2540. Epub 2018 Jan 1.

PMID:
29291349
7.

Identification of CYP443D1 (CYP74 clan) of Nematostella vectensis as a first cnidarian epoxyalcohol synthase and insights into its catalytic mechanism.

Toporkova YY, Gorina SS, Mukhitova FK, Hamberg M, Ilyina TM, Mukhtarova LS, Grechkin AN.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Oct;1862(10 Pt A):1099-1109. doi: 10.1016/j.bbalip.2017.07.015. Epub 2017 Aug 1.

PMID:
28774820
8.

An allene oxide and 12-oxophytodienoic acid are key intermediates in jasmonic acid biosynthesis by Fusarium oxysporum.

Oliw EH, Hamberg M.

J Lipid Res. 2017 Aug;58(8):1670-1680. doi: 10.1194/jlr.M077305. Epub 2017 Jun 1.

9.

The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity.

Kalms J, Banthiya S, Galemou Yoga E, Hamberg M, Holzhutter HG, Kuhn H, Scheerer P.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 May;1862(5):463-473. doi: 10.1016/j.bbalip.2017.01.003. Epub 2017 Jan 14.

PMID:
28093240
10.

Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa.

Banthiya S, Kalms J, Galemou Yoga E, Ivanov I, Carpena X, Hamberg M, Kuhn H, Scheerer P.

Biochim Biophys Acta. 2016 Nov;1861(11):1681-1692. doi: 10.1016/j.bbalip.2016.08.002. Epub 2016 Aug 5.

PMID:
27500637
11.

The activity of HYDROPEROXIDE LYASE 1 regulates accumulation of galactolipids containing 12-oxo-phytodienoic acid in Arabidopsis.

Nilsson AK, Fahlberg P, Johansson ON, Hamberg M, Andersson MX, Ellerström M.

J Exp Bot. 2016 Sep;67(17):5133-44. doi: 10.1093/jxb/erw278. Epub 2016 Jul 15.

12.

Kinetic investigation of human 5-lipoxygenase with arachidonic acid.

Mittal M, Kumar RB, Balagunaseelan N, Hamberg M, Jegerschöld C, Rådmark O, Haeggström JZ, Rinaldo-Matthis A.

Bioorg Med Chem Lett. 2016 Aug 1;26(15):3547-51. doi: 10.1016/j.bmcl.2016.06.025. Epub 2016 Jun 11.

PMID:
27363940
13.

MiRTargetLink--miRNAs, Genes and Interaction Networks.

Hamberg M, Backes C, Fehlmann T, Hart M, Meder B, Meese E, Keller A.

Int J Mol Sci. 2016 Apr 14;17(4):564. doi: 10.3390/ijms17040564.

14.

Screen Identifying Arabidopsis Transcription Factors Involved in the Response to 9-Lipoxygenase-Derived Oxylipins.

Walper E, Weiste C, Mueller MJ, Hamberg M, Dröge-Laser W.

PLoS One. 2016 Apr 13;11(4):e0153216. doi: 10.1371/journal.pone.0153216. eCollection 2016.

15.

A dynamic Asp-Arg interaction is essential for catalysis in microsomal prostaglandin E2 synthase.

Brock JS, Hamberg M, Balagunaseelan N, Goodman M, Morgenstern R, Strandback E, Samuelsson B, Rinaldo-Matthis A, Haeggström JZ.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):972-7. doi: 10.1073/pnas.1522891113. Epub 2016 Jan 11.

16.

Replacement of two amino acids of 9R-dioxygenase-allene oxide synthase of Aspergillus niger inverts the chirality of the hydroperoxide and the allene oxide.

Sooman L, Wennman A, Hamberg M, Hoffmann I, Oliw EH.

Biochim Biophys Acta. 2016 Feb;1861(2):108-118. doi: 10.1016/j.bbalip.2015.11.009. Epub 2015 Nov 18.

PMID:
26603902
17.

9-Lipoxygenase-Derived Oxylipins Activate Brassinosteroid Signaling to Promote Cell Wall-Based Defense and Limit Pathogen Infection.

Marcos R, Izquierdo Y, Vellosillo T, Kulasekaran S, Cascón T, Hamberg M, Castresana C.

Plant Physiol. 2015 Nov;169(3):2324-34. doi: 10.1104/pp.15.00992. Epub 2015 Sep 28.

18.

Oxylipins in moss development and defense.

Ponce de León I, Hamberg M, Castresana C.

Front Plant Sci. 2015 Jul 3;6:483. doi: 10.3389/fpls.2015.00483. eCollection 2015. Review.

19.

Manganese lipoxygenase of F. oxysporum and the structural basis for biosynthesis of distinct 11-hydroperoxy stereoisomers.

Wennman A, Magnuson A, Hamberg M, Oliw EH.

J Lipid Res. 2015 Aug;56(8):1606-15. doi: 10.1194/jlr.M060178. Epub 2015 Jun 25.

20.

Stereospecific biosynthesis of (9S,13S)-10-oxo-phytoenoic acid in young maize roots.

Ogorodnikova AV, Gorina SS, Mukhtarova LS, Mukhitova FK, Toporkova YY, Hamberg M, Grechkin AN.

Biochim Biophys Acta. 2015 Sep;1851(9):1262-70. doi: 10.1016/j.bbalip.2015.05.004. Epub 2015 May 22.

PMID:
26008579
21.

Predator lipids induce paralytic shellfish toxins in bloom-forming algae.

Selander E, Kubanek J, Hamberg M, Andersson MX, Cervin G, Pavia H.

Proc Natl Acad Sci U S A. 2015 May 19;112(20):6395-400. doi: 10.1073/pnas.1420154112. Epub 2015 Apr 27.

22.

The Physcomitrella patens unique alpha-dioxygenase participates in both developmental processes and defense responses.

Machado L, Castro A, Hamberg M, Bannenberg G, Gaggero C, Castresana C, de León IP.

BMC Plant Biol. 2015 Feb 12;15:45. doi: 10.1186/s12870-015-0439-z.

23.

Involvement of the electrophilic isothiocyanate sulforaphane in Arabidopsis local defense responses.

Andersson MX, Nilsson AK, Johansson ON, Boztaş G, Adolfsson LE, Pinosa F, Petit CG, Aronsson H, Mackey D, Tör M, Hamberg M, Ellerström M.

Plant Physiol. 2015 Jan;167(1):251-61. doi: 10.1104/pp.114.251892. Epub 2014 Nov 4.

24.

Rational design of a ligand-based antagonist of jasmonate perception.

Monte I, Hamberg M, Chini A, Gimenez-Ibanez S, García-Casado G, Porzel A, Pazos F, Boter M, Solano R.

Nat Chem Biol. 2014 Aug;10(8):671-6. doi: 10.1038/nchembio.1575. Epub 2014 Jul 6.

PMID:
24997606
25.

Experimental studies of H13CO+ recombining with electrons at energies between 2-50,000 meV.

Hamberg M, Kashperka I, Thomas RD, Roueff E, Zhaunerchyk V, Danielsson M, af Ugglas M, Österdah F, Vigren E, Kaminska M, Källberg A, Simonsson A, Paal A, Gerin M, Larsson M, Geppert WD.

J Phys Chem A. 2014 Aug 7;118(31):6034-49. doi: 10.1021/jp5032306. Epub 2014 Jul 24.

PMID:
24945616
26.

WITHDRAWN: Structural and mechanistic studies of hydroperoxide conversions catalyzed by a CYP74 clan epoxy alcohol synthase from amphioxus (Branchiostoma floridae).

Hamberg M, Khairutdinov BI, Scholz J, Brodhun F, Hornung E, Feussner I, Grechkin AN.

J Lipid Res. 2014 Mar 4. [Epub ahead of print]

27.

Diversity of Δ12 fatty acid desaturases in santalaceae and their role in production of seed oil acetylenic fatty acids.

Okada S, Zhou XR, Damcevski K, Gibb N, Wood C, Hamberg M, Haritos VS.

J Biol Chem. 2013 Nov 8;288(45):32405-13. doi: 10.1074/jbc.M113.511931. Epub 2013 Sep 23.

28.

An iron 13S-lipoxygenase with an α-linolenic acid specific hydroperoxidase activity from Fusarium oxysporum.

Brodhun F, Cristobal-Sarramian A, Zabel S, Newie J, Hamberg M, Feussner I.

PLoS One. 2013 May 31;8(5):e64919. doi: 10.1371/journal.pone.0064919. Print 2013.

29.

Dissociative recombination of CH4(+).

Thomas RD, Kashperka I, Vigren E, Geppert WD, Hamberg M, Larsson M, af Ugglas M, Zhaunerchyk V.

J Phys Chem A. 2013 Oct 3;117(39):9999-10005. doi: 10.1021/jp400353x. Epub 2013 May 29.

PMID:
23651407
30.

Resolving resolvins.

Haeggström JZ, Hamberg M.

Chem Biol. 2013 Feb 21;20(2):138-40. doi: 10.1016/j.chembiol.2013.02.003.

31.

Defense activated by 9-lipoxygenase-derived oxylipins requires specific mitochondrial proteins.

Vellosillo T, Aguilera V, Marcos R, Bartsch M, Vicente J, Cascón T, Hamberg M, Castresana C.

Plant Physiol. 2013 Feb;161(2):617-27. doi: 10.1104/pp.112.207514. Epub 2012 Dec 12.

32.

The convergent evolution of defensive polyacetylenic fatty acid biosynthesis genes in soldier beetles.

Haritos VS, Horne I, Damcevski K, Glover K, Gibb N, Okada S, Hamberg M.

Nat Commun. 2012;3:1150. doi: 10.1038/ncomms2147.

PMID:
23093187
33.

Combined crossed beam and theoretical studies of the N(2D) + C2H4 reaction and implications for atmospheric models of Titan.

Balucani N, Skouteris D, Leonori F, Petrucci R, Hamberg M, Geppert WD, Casavecchia P, Rosi M.

J Phys Chem A. 2012 Nov 1;116(43):10467-79. doi: 10.1021/jp3072316. Epub 2012 Oct 19.

PMID:
23016665
34.

Crystal structures of Physcomitrella patens AOC1 and AOC2: insights into the enzyme mechanism and differences in substrate specificity.

Neumann P, Brodhun F, Sauer K, Herrfurth C, Hamberg M, Brinkmann J, Scholz J, Dickmanns A, Feussner I, Ficner R.

Plant Physiol. 2012 Nov;160(3):1251-66. doi: 10.1104/pp.112.205138. Epub 2012 Sep 17.

35.

Novel insights into cyclooxygenases, linoleate diol synthases, and lipoxygenases from deuterium kinetic isotope effects and oxidation of substrate analogs.

Hoffmann I, Hamberg M, Lindh R, Oliw EH.

Biochim Biophys Acta. 2012 Dec;1821(12):1508-17. doi: 10.1016/j.bbalip.2012.09.001. Epub 2012 Sep 12.

PMID:
22982814
36.

Catalytic convergence of manganese and iron lipoxygenases by replacement of a single amino acid.

Wennman A, Jernerén F, Hamberg M, Oliw EH.

J Biol Chem. 2012 Sep 14;287(38):31757-65. doi: 10.1074/jbc.M112.364331. Epub 2012 Jul 20.

37.

Identification of avian wax synthases.

Biester EM, Hellenbrand J, Gruber J, Hamberg M, Frentzen M.

BMC Biochem. 2012 Feb 4;13:4. doi: 10.1186/1471-2091-13-4.

38.

Role of 9-lipoxygenase and α-dioxygenase oxylipin pathways as modulators of local and systemic defense.

Vicente J, Cascón T, Vicedo B, García-Agustín P, Hamberg M, Castresana C.

Mol Plant. 2012 Jul;5(4):914-28. doi: 10.1093/mp/ssr105. Epub 2011 Dec 22.

39.

Biochemical characterization of a chloroplast localized fatty acid reductase from Arabidopsis thaliana.

Doan TT, Domergue F, Fournier AE, Vishwanath SJ, Rowland O, Moreau P, Wood CC, Carlsson AS, Hamberg M, Hofvander P.

Biochim Biophys Acta. 2012 Sep;1821(9):1244-55. doi: 10.1016/j.bbalip.2011.10.019. Epub 2011 Nov 30.

PMID:
22166367
40.

Fatty acyl-CoA reductases of birds.

Hellenbrand J, Biester EM, Gruber J, Hamberg M, Frentzen M.

BMC Biochem. 2011 Dec 12;12:64. doi: 10.1186/1471-2091-12-64.

41.

Targeted knock-down of a structurally atypical zebrafish 12S-lipoxygenase leads to severe impairment of embryonic development.

Haas U, Raschperger E, Hamberg M, Samuelsson B, Tryggvason K, Haeggström JZ.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20479-84. doi: 10.1073/pnas.1117094108. Epub 2011 Dec 5.

42.

Linolenate 9R-dioxygenase and allene oxide synthase activities of Lasiodiplodia theobromae.

Jernerén F, Eng F, Hamberg M, Oliw EH.

Lipids. 2012 Jan;47(1):65-73. doi: 10.1007/s11745-011-3622-5. Epub 2011 Nov 3.

PMID:
22048860
43.

A prokaryotic acyl-CoA reductase performing reduction of fatty acyl-CoA to fatty alcohol.

Hofvander P, Doan TT, Hamberg M.

FEBS Lett. 2011 Nov 16;585(22):3538-43. doi: 10.1016/j.febslet.2011.10.016. Epub 2011 Oct 19.

44.

Applications of stereospecifically-labeled Fatty acids in oxygenase and desaturase biochemistry.

Brash AR, Schneider C, Hamberg M.

Lipids. 2012 Feb;47(2):101-16. doi: 10.1007/s11745-011-3612-7. Epub 2011 Oct 5. Review.

45.

Stereoselective oxidation of regioisomeric octadecenoic acids by fatty acid dioxygenases.

Oliw EH, Wennman A, Hoffmann I, Garscha U, Hamberg M, Jernerén F.

J Lipid Res. 2011 Nov;52(11):1995-2004. doi: 10.1194/jlr.M018259. Epub 2011 Aug 18.

46.

Efficient and specific conversion of 9-lipoxygenase hydroperoxides in the beetroot. Formation of pinellic acid.

Hamberg M, Olsson U.

Lipids. 2011 Sep;46(9):873-8. doi: 10.1007/s11745-011-3592-7. Epub 2011 Jul 10.

PMID:
21744276
47.

Antagonistic role of 9-lipoxygenase-derived oxylipins and ethylene in the control of oxidative stress, lipid peroxidation and plant defence.

López MA, Vicente J, Kulasekaran S, Vellosillo T, Martínez M, Irigoyen ML, Cascón T, Bannenberg G, Hamberg M, Castresana C.

Plant J. 2011 Aug;67(3):447-58. doi: 10.1111/j.1365-313X.2011.04608.x. Epub 2011 Jun 6.

48.
49.

Biosynthesis of 14,15-hepoxilins in human l1236 Hodgkin lymphoma cells and eosinophils.

Brunnström A, Hamberg M, Griffiths WJ, Mannervik B, Claesson HE.

Lipids. 2011 Jan;46(1):69-79. doi: 10.1007/s11745-010-3485-1. Epub 2010 Oct 29.

PMID:
21046276
50.

Emerging complexity in reactive oxygen species production and signaling during the response of plants to pathogens.

Vellosillo T, Vicente J, Kulasekaran S, Hamberg M, Castresana C.

Plant Physiol. 2010 Oct;154(2):444-8. doi: 10.1104/pp.110.161273. No abstract available.

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