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Items: 1 to 50 of 58

1.

Autoantibodies reactive to PEP08 are clinically related with morbidity and severity of interstitial lung disease in connective tissue diseases.

Okumura M, Ozawa T, Hamana H, Norimatsu Y, Tsuda R, Kobayashi E, Shinoda K, Taki H, Tobe K, Imura J, Sugiyama E, Kishi H, Muraguchi A.

Eur J Immunol. 2018 Jul 10. doi: 10.1002/eji.201747381. [Epub ahead of print]

PMID:
29989658
2.

Introduction of Genetically Modified CD3ζ Improves Proliferation and Persistence of Antigen-Specific CTLs.

Miyao K, Terakura S, Okuno S, Julamanee J, Watanabe K, Hamana H, Kishi H, Sakemura R, Koyama D, Goto T, Nishida T, Murata M, Kiyoi H.

Cancer Immunol Res. 2018 Jun;6(6):733-744. doi: 10.1158/2326-6066.CIR-17-0538. Epub 2018 Apr 13.

PMID:
29653982
3.

Bladder cancer-associated cancer-testis antigen-derived long peptides encompassing both CTL and promiscuous HLA class II-restricted Th cell epitopes induced CD4+ T cells expressing converged T-cell receptor genes in vitro.

Tsuruta M, Ueda S, Yew PY, Fukuda I, Yoshimura S, Kishi H, Hamana H, Hirayama M, Yatsuda J, Irie A, Senju S, Yuba E, Kamba T, Eto M, Nakayama H, Nishimura Y.

Oncoimmunology. 2018 Jan 5;7(4):e1415687. doi: 10.1080/2162402X.2017.1415687. eCollection 2018.

PMID:
29632734
4.

Identification of Tumoricidal TCRs from Tumor-Infiltrating Lymphocytes by Single-Cell Analysis.

Shitaoka K, Hamana H, Kishi H, Hayakawa Y, Kobayashi E, Sukegawa K, Piao X, Lyu F, Nagata T, Sugiyama D, Nishikawa H, Tanemura A, Katayama I, Murahashi M, Takamatsu Y, Tani K, Ozawa T, Muraguchi A.

Cancer Immunol Res. 2018 Apr;6(4):378-388. doi: 10.1158/2326-6066.CIR-17-0489. Epub 2018 Feb 23.

PMID:
29475880
5.

Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack.

Espinoza JL, Elbadry MI, Chonabayashi K, Yoshida Y, Katagiri T, Harada K, Nakagawa N, Zaimoku Y, Imi T, Hassanein HA, Khalifa A Noreldin A, Takenaka K, Akashi K, Hamana H, Kishi H, Akatsuka Y, Nakao S.

Blood Adv. 2018 Feb 27;2(4):390-400. doi: 10.1182/bloodadvances.2017013342.

6.

Highly functional T-cell receptor repertoires are abundant in stem memory T cells and highly shared among individuals.

Miyama T, Kawase T, Kitaura K, Chishaki R, Shibata M, Oshima K, Hamana H, Kishi H, Muraguchi A, Kuzushima K, Saji H, Shin-I T, Suzuki R, Ichinohe T.

Sci Rep. 2017 Jun 16;7(1):3663. doi: 10.1038/s41598-017-03855-x.

7.

Association Between High-Avidity T-Cell Receptors, Induced by α-Fetoprotein-Derived Peptides, and Anti-Tumor Effects in Patients With Hepatocellular Carcinoma.

Nakagawa H, Mizukoshi E, Kobayashi E, Tamai T, Hamana H, Ozawa T, Kishi H, Kitahara M, Yamashita T, Arai K, Terashima T, Iida N, Fushimi K, Muraguchi A, Kaneko S.

Gastroenterology. 2017 May;152(6):1395-1406.e10. doi: 10.1053/j.gastro.2017.02.001. Epub 2017 Feb 7.

PMID:
28188748
8.

TRAIL-receptor 1 IgM antibodies strongly induce apoptosis in human cancer cells in vitro and in vivo.

Piao X, Ozawa T, Hamana H, Shitaoka K, Jin A, Kishi H, Muraguchi A.

Oncoimmunology. 2016 May 4;5(5):e1131380. doi: 10.1080/2162402X.2015.1131380. eCollection 2016 May.

9.

A novel, rapid and efficient method of cloning functional antigen-specific T-cell receptors from single human and mouse T-cells.

Hamana H, Shitaoka K, Kishi H, Ozawa T, Muraguchi A.

Biochem Biophys Res Commun. 2016 Jun 10;474(4):709-714. doi: 10.1016/j.bbrc.2016.05.015. Epub 2016 May 4.

PMID:
27155153
10.

Identification of broadly conserved cross-species protective Leishmania antigen and its responding CD4+ T cells.

Mou Z, Li J, Boussoffara T, Kishi H, Hamana H, Ezzati P, Hu C, Yi W, Liu D, Khadem F, Okwor I, Jia P, Shitaoka K, Wang S, Ndao M, Petersen C, Chen J, Rafati S, Louzir H, Muraguchi A, Wilkins JA, Uzonna JE.

Sci Transl Med. 2015 Oct 21;7(310):310ra167. doi: 10.1126/scitranslmed.aac5477.

PMID:
26491077
11.

Supersensitive detection and discrimination of enantiomers by dorsal olfactory receptors: evidence for hierarchical odour coding.

Sato T, Kobayakawa R, Kobayakawa K, Emura M, Itohara S, Kizumi M, Hamana H, Tsuboi A, Hirono J.

Sci Rep. 2015 Sep 11;5:14073. doi: 10.1038/srep14073.

12.

A new methodology for functionalization at the 3-position of indoles by a combination of boron Lewis acid with nitriles.

Mizoi K, Mashima Y, Kawashima Y, Takahashi M, Mimori S, Hosokawa M, Murakami Y, Hamana H.

Chem Pharm Bull (Tokyo). 2015;63(7):538-45. doi: 10.1248/cpb.c15-00157.

13.

Monoclonal antibody against citrullinated peptides obtained from rheumatoid arthritis patients reacts with numerous citrullinated microbial and food proteins.

Tsuda R, Ozawa T, Kobayashi E, Hamana H, Taki H, Tobe K, Sugiyama E, Iwamoto M, Imura J, Kishi H, Muraguchi A.

Arthritis Rheumatol. 2015 May;67(8):2020-31. doi: 10.1002/art.39161.

14.

Evaluation of synthetic naphthalene derivatives as novel chemical chaperones that mimic 4-phenylbutyric acid.

Mimori S, Koshikawa Y, Mashima Y, Mitsunaga K, Kawada K, Kaneko M, Okuma Y, Nomura Y, Murakami Y, Kanzaki T, Hamana H.

Bioorg Med Chem Lett. 2015 Feb 15;25(4):811-4. doi: 10.1016/j.bmcl.2014.12.080. Epub 2015 Jan 5.

PMID:
25595686
15.

A chimeric antigen receptor for TRAIL-receptor 1 induces apoptosis in various types of tumor cells.

Kobayashi E, Kishi H, Ozawa T, Hamana H, Nakagawa H, Jin A, Lin Z, Muraguchi A.

Biochem Biophys Res Commun. 2014 Oct 31;453(4):798-803. doi: 10.1016/j.bbrc.2014.10.024. Epub 2014 Oct 14.

PMID:
25445592
16.

Retroviral vectors for homologous recombination provide efficient cloning and expression in mammalian cells.

Kobayashi E, Kishi H, Ozawa T, Horii M, Hamana H, Nagai T, Muraguchi A.

Biochem Biophys Res Commun. 2014 Feb 14;444(3):319-24. doi: 10.1016/j.bbrc.2014.01.049. Epub 2014 Jan 22.

PMID:
24462869
17.

A new cloning and expression system yields and validates TCRs from blood lymphocytes of patients with cancer within 10 days.

Kobayashi E, Mizukoshi E, Kishi H, Ozawa T, Hamana H, Nagai T, Nakagawa H, Jin A, Kaneko S, Muraguchi A.

Nat Med. 2013 Nov;19(11):1542-6. doi: 10.1038/nm.3358. Epub 2013 Oct 13.

PMID:
24121927
18.

4-Phenylbutyric acid protects against neuronal cell death by primarily acting as a chemical chaperone rather than histone deacetylase inhibitor.

Mimori S, Ohtaka H, Koshikawa Y, Kawada K, Kaneko M, Okuma Y, Nomura Y, Murakami Y, Hamana H.

Bioorg Med Chem Lett. 2013 Nov 1;23(21):6015-8. doi: 10.1016/j.bmcl.2013.08.001. Epub 2013 Aug 11.

PMID:
24044874
19.

Selective CB2 agonists with anti-pruritic activity: discovery of potent and orally available bicyclic 2-pyridones.

Kusakabe K, Iso Y, Tada Y, Sakagami M, Morioka Y, Chomei N, Shinonome S, Kawamoto K, Takenaka H, Yasui K, Hamana H, Hanasaki K.

Bioorg Med Chem. 2013 Jun 1;21(11):3154-63. doi: 10.1016/j.bmc.2013.03.030. Epub 2013 Mar 30.

PMID:
23623258
20.

Design, synthesis, and binding mode prediction of 2-pyridone-based selective CB2 receptor agonists.

Kusakabe K, Tada Y, Iso Y, Sakagami M, Morioka Y, Chomei N, Shinonome S, Kawamoto K, Takenaka H, Yasui K, Hamana H, Hanasaki K.

Bioorg Med Chem. 2013 Apr 1;21(7):2045-55. doi: 10.1016/j.bmc.2013.01.006. Epub 2013 Jan 16.

PMID:
23395112
21.

Functional reconstitution of olfactory receptor complex on baculovirus.

Mitsui K, Sakihama T, Takahashi K, Masuda K, Fukuda R, Hamana H, Sato T, Hamakubo T.

Chem Senses. 2012 Nov;37(9):837-47. doi: 10.1093/chemse/bjs067. Epub 2012 Sep 5.

PMID:
22952299
22.

Protective effects of 4-phenylbutyrate derivatives on the neuronal cell death and endoplasmic reticulum stress.

Mimori S, Okuma Y, Kaneko M, Kawada K, Hosoi T, Ozawa K, Nomura Y, Hamana H.

Biol Pharm Bull. 2012;35(1):84-90.

23.

Expression of the ubiquitin ligase HRD1 in neural stem/progenitor cells of the adult mouse brain.

Kawada K, Kaneko M, Nomura Y, Mimori S, Hamana H, Ogita K, Murayama T, Fujino H, Okuma Y.

J Pharmacol Sci. 2011;117(3):208-12. Epub 2011 Oct 25.

24.

Salicylate restores transport function and anion exchanger activity of missense pendrin mutations.

Ishihara K, Okuyama S, Kumano S, Iida K, Hamana H, Murakoshi M, Kobayashi T, Usami S, Ikeda K, Haga Y, Tsumoto K, Nakamura H, Hirasawa N, Wada H.

Hear Res. 2010 Dec 1;270(1-2):110-8. doi: 10.1016/j.heares.2010.08.015. Epub 2010 Sep 6.

PMID:
20826203
25.

Atomic force microscopy imaging of the structure of the motor protein prestin reconstituted into an artificial lipid bilayer.

Kumano S, Murakoshi M, Iida K, Hamana H, Wada H.

FEBS Lett. 2010 Jul 2;584(13):2872-6. doi: 10.1016/j.febslet.2010.04.076. Epub 2010 May 7.

26.

Heterologous functional expression system for odorant receptors.

Hamana H, Shou-xin L, Breuils L, Hirono J, Sato T.

J Neurosci Methods. 2010 Jan 15;185(2):213-20. doi: 10.1016/j.jneumeth.2009.09.024. Epub 2009 Sep 30.

PMID:
19799933
27.

Architecture of odor information processing in the olfactory system.

Sato T, Hirono J, Hamana H, Ishikawa T, Shimizu A, Takashima I, Kajiwara R, Iijima T.

Anat Sci Int. 2008 Dec;83(4):195-206. doi: 10.1111/j.1447-073X.2007.00215.x.

PMID:
19159347
28.

Bioelectrochemical conversion of urea to nitrogen using aminated carbon electrode.

Watanabe H, Nishi H, Hamana H, Sekioka N, Wang X, Uchiyama S.

J Environ Sci (China). 2009;21 Suppl 1:S96-9. doi: 10.1016/S1001-0742(09)60047-4.

PMID:
25084444
29.

Ca2+ inhibits the association of memantine with N-methyl-D-aspartate (NMDA) receptor-gated ion channels.

Fujimoto M, Iida H, Homma T, Kimura I, Mori M, Hamana H.

Biol Pharm Bull. 2008 Sep;31(9):1813-5.

30.

Crystal structure analysis of the PHD domain of the transcription co-activator Pygopus.

Nakamura Y, Umehara T, Hamana H, Hayashizaki Y, Inoue M, Kigawa T, Shirouzu M, Terada T, Tanaka A, Padmanabhan B, Yokoyama S.

J Mol Biol. 2007 Jun 29;370(1):80-92. Epub 2007 Apr 20.

PMID:
17499269
31.

Crystal structure of the human BRD2 bromodomain: insights into dimerization and recognition of acetylated histone H4.

Nakamura Y, Umehara T, Nakano K, Jang MK, Shirouzu M, Morita S, Uda-Tochio H, Hamana H, Terada T, Adachi N, Matsumoto T, Tanaka A, Horikoshi M, Ozato K, Padmanabhan B, Yokoyama S.

J Biol Chem. 2007 Feb 9;282(6):4193-201. Epub 2006 Dec 5.

32.

Application of polymaleimidostyrene as a convenient immobilization reagent of enzyme in biosensor.

Uchiyama S, Tomita R, Sekioka N, Imaizumi E, Hamana H, Hagiwara T.

Bioelectrochemistry. 2006 May;68(2):119-25. Epub 2005 Jul 20.

PMID:
16039167
33.

Crystal structure of a predicted phosphoribosyltransferase (TT1426) from Thermus thermophilus HB8 at 2.01 A resolution.

Kukimoto-Niino M, Shibata R, Murayama K, Hamana H, Nishimoto M, Bessho Y, Terada T, Shirouzu M, Kuramitsu S, Yokoyama S.

Protein Sci. 2005 Mar;14(3):823-7. Epub 2005 Feb 2.

34.

Oligomer preparation from hexane by radical polyaddition with bis(alpha-trifluoromethyl-beta,beta-difluorovinyl) terephthalate.

Narita T, Hamana H, Hattori S.

Chem Commun (Camb). 2004 Oct 21;(20):2340-1. Epub 2004 Sep 7.

PMID:
15490010
35.

Sialyl Lewis X-carboxymethylpullulan conjugate: a novel homing device to spleen and lymph nodes.

Horie K, Sakagami M, Masuda K, Notoya M, Hamana H, Yoshikawa T, Hirano K.

Biol Pharm Bull. 2004 Aug;27(8):1275-80.

36.

Solution structure of a BolA-like protein from Mus musculus.

Kasai T, Inoue M, Koshiba S, Yabuki T, Aoki M, Nunokawa E, Seki E, Matsuda T, Matsuda N, Tomo Y, Shirouzu M, Terada T, Obayashi N, Hamana H, Shinya N, Tatsuguchi A, Yasuda S, Yoshida M, Hirota H, Matsuo Y, Tani K, Suzuki H, Arakawa T, Carninci P, Kawai J, Hayashizaki Y, Kigawa T, Yokoyama S.

Protein Sci. 2004 Feb;13(2):545-8. Epub 2004 Jan 10.

37.

Crystal structure of the conserved protein TT1542 from Thermus thermophilus HB8.

Handa N, Terada T, Kamewari Y, Hamana H, Tame JR, Park SY, Kinoshita K, Ota M, Nakamura H, Kuramitsu S, Shirouzu M, Yokoyama S.

Protein Sci. 2003 Aug;12(8):1621-32.

38.

Sensitivity-dependent hierarchical receptor codes for odors.

Hamana H, Hirono J, Kizumi M, Sato T.

Chem Senses. 2003 Feb;28(2):87-104. Erratum in: Chem Senses. 2003 Mar;28(3):267.

PMID:
12588732
39.

Evaluation of carboxymethylpullulan as a novel carrier for targeting immune tissues.

Masuda K, Sakagami M, Horie K, Nogusa H, Hamana H, Hirano K.

Pharm Res. 2001 Feb;18(2):217-23.

PMID:
11405294
40.
41.

Improved in vivo antitumor efficacy and reduced systemic toxicity of carboxymethylpullulan-peptide-doxorubicin conjugates.

Nogusa H, Hamana H, Uchida N, Maekawa R, Yoshioka T.

Jpn J Cancer Res. 2000 Dec;91(12):1333-8.

42.

Synthesis of sialyl Lewis X-polysaccharide conjugates.

Sakagami M, Horie K, Nakamoto K, Kawaguchi T, Hamana H.

Chem Pharm Bull (Tokyo). 2000 Sep;48(9):1256-63.

PMID:
10993222
43.

Effect of the sialyl Lewis X (SLe(x)) moiety on splenic accumulation of SLe(x)-carboxymethylpullulan conjugate.

Horie K, Sakagami M, Kuramochi K, Ito T, Hamana H.

Microbiol Immunol. 2000;44(5):401-4.

44.
45.

Structure-activity relationships of carboxymethylpullulan-peptide-doxorubicin conjugates--systematic modification of peptide spacers.

Nogusa H, Yano T, Kashima N, Yamamoto K, Okuno S, Hamana H.

Bioorg Med Chem Lett. 2000 Feb 7;10(3):227-30.

PMID:
10698441
46.

Syntheses and evaluation of biantennary oligosaccharide ligands mimicking sialyl Lewis X.

Sakagami M, Horie K, Higashi K, Yamada H, Hamana H.

Chem Pharm Bull (Tokyo). 1999 Sep;47(9):1237-45.

PMID:
10517006
47.

Sensitive detection of the binding of E2F to its promoter by exonuclease III- and BssHII-protection PCR assays.

Han B, Hamana H, Shinozawa T.

J Biochem Biophys Methods. 1999 Feb 25;39(1-2):85-92.

PMID:
10344502
48.

Enhanced accumulation of sialyl Lewis X-carboxymethylpullulan conjugate in acute inflammatory lesion.

Horie K, Sakagami M, Kuramochi K, Hanasaki K, Hamana H, Ito T.

Pharm Res. 1999 Feb;16(2):314-20.

PMID:
10100320
49.

Medium temperature, 310 K, provides single crystals of orotate phosphoribosyltransferase from Thermus thermophilus.

Hamana H, Moriyama H, Shinozawa T, Tanaka N.

Acta Crystallogr D Biol Crystallogr. 1999 Jan;55(Pt 1):345-6. Epub 1999 Jan 1.

PMID:
10089446

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