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Inhibitory Effects of Sodium Alginate on Hepatic Steatosis in Mice Induced by a Methionine- and Choline-deficient Diet.

Kawauchi S, Horibe S, Sasaki N, Tanahashi T, Mizuno S, Hamaguchi T, Rikitake Y.

Mar Drugs. 2019 Feb 9;17(2). pii: E104. doi: 10.3390/md17020104.


Cerebral hemorrhagic stroke associated with cerebral amyloid angiopathy in young adults about 3 decades after neurosurgeries in their infancy.

Hamaguchi T, Komatsu J, Sakai K, Noguchi-Shinohara M, Aoki S, Ikeuchi T, Yamada M.

J Neurol Sci. 2019 Feb 1;399:3-5. doi: 10.1016/j.jns.2019.01.051. [Epub ahead of print] No abstract available.


Identification of novel protein domain for sialyloligosaccharide binding essential to Mycoplasma mobile gliding.

Hamaguchi T, Kawakami M, Furukawa H, Miyata M.

FEMS Microbiol Lett. 2019 Feb 1;366(3). pii: fnz016. doi: 10.1093/femsle/fnz016.


Phase II trial of aflibercept with FOLFIRI as a 2nd-line treatment for Japanese patients with metastatic colorectal cancer.

Denda T, Sakai D, Hamaguchi T, Sugimoto N, Ura T, Yamazaki K, Fujii H, Kajiwara T, Nakajima TE, Takahashi S, Otsu S, Komatsu Y, Nagashima F, Moriwaki T, Esaki T, Sato T, Itabashi M, Oki E, Sasaki T, Sunaga Y, Ziti-Ljajic S, Brillac C, Yoshino T.

Cancer Sci. 2019 Jan 18. doi: 10.1111/cas.13943. [Epub ahead of print]


Serum level of octanoic acid predicts the efficacy of chemotherapy for colorectal cancer.

Iemoto T, Nishiumi S, Kobayashi T, Fujigaki S, Hamaguchi T, Kato K, Shoji H, Matsumura Y, Honda K, Yoshida M.

Oncol Lett. 2019 Jan;17(1):831-842. doi: 10.3892/ol.2018.9731. Epub 2018 Nov 19.


Association between UGT1A1 gene polymorphism and safety and efficacy of irinotecan monotherapy as the third-line treatment for advanced gastric cancer.

Yamaguchi T, Iwasa S, Shoji H, Honma Y, Takashima A, Kato K, Hamaguchi T, Higuchi K, Boku N.

Gastric Cancer. 2019 Jan 2. doi: 10.1007/s10120-018-00917-5. [Epub ahead of print]


Effect of switching from conventional continuous subcutaneous insulin infusion to sensor augmented pump therapy on glycemic profile in Japanese patients with type 1 diabetes.

Matsuoka A, Hirota Y, Urai S, Hamaguchi T, Takeuchi T, Miura H, Suematsu N, So A, Nakamura T, Komada H, Okada Y, Sakaguchi K, Ogawa W.

Diabetol Int. 2018 Jan 22;9(3):201-207. doi: 10.1007/s13340-018-0344-4. eCollection 2018 Jul.


Quantification of hydrogen production by intestinal bacteria that are specifically dysregulated in Parkinson's disease.

Suzuki A, Ito M, Hamaguchi T, Mori H, Takeda Y, Baba R, Watanabe T, Kurokawa K, Asakawa S, Hirayama M, Ohno K.

PLoS One. 2018 Dec 26;13(12):e0208313. doi: 10.1371/journal.pone.0208313. eCollection 2018.


A clickable caging group as a new platform for modular caged compounds with improved photochemical properties.

Suzuki AZ, Sekine R, Takeda S, Aikawa R, Shiraishi Y, Hamaguchi T, Okuno H, Tamamura H, Furuta T.

Chem Commun (Camb). 2019 Jan 3;55(4):451-454. doi: 10.1039/c8cc07981a.


[III. Treatment Strategy for Squamous Cell Carcinoma of the Anus].

Hamaguchi T.

Gan To Kagaku Ryoho. 2018 Nov;45(11):1598-1601. Japanese. No abstract available.


Omega-3 polyunsaturated fatty acids and psychological intervention for workers with mild to moderate depression: A double-blind randomized controlled trial.

Tayama J, Ogawa S, Nakaya N, Sone T, Hamaguchi T, Takeoka A, Hamazaki K, Okamura H, Yajima J, Kobayashi M, Hayashida M, Shirabe S.

J Affect Disord. 2019 Feb 15;245:364-370. doi: 10.1016/j.jad.2018.11.039. Epub 2018 Nov 6.


Specific amyloid-β42 deposition in the brain of a Gerstmann-Sträussler-Scheinker disease patient with a P105L mutation on the prion protein gene.

Furukawa F, Sanjo N, Kobayashi A, Hamaguchi T, Yamada M, Kitamoto T, Mizusawa H, Yokota T.

Prion. 2018;12(5-6):315-319. doi: 10.1080/19336896.2018.1541689. Epub 2018 Nov 13.


The prescription rates of glucagon for hypoglycemia by pediatricians and physicians are low in Japan.

Matsumoto M, Awano H, Hirota Y, Nagai M, Bo R, Matsuoka A, Hamaguchi T, Takeuchi T, Nakagawa Y, Ogawa W, Iijima K.

Endocrine. 2018 Oct 26. doi: 10.1007/s12020-018-1793-z. [Epub ahead of print]


Current clinical practice of adjuvant chemotherapy for patients with 'high-risk' Stage II colorectal cancer in Japan: a questionnaire survey in the JCOG Study Group.

Ishiguro M, Ueno H, Kanemitsu Y, Hamaguchi T, Shida D, Shimada Y; Colorectal Cancer Study Group of Japan Clinical Oncology Group (JCOG).

Jpn J Clin Oncol. 2018 Dec 1;48(12):1109-1112. doi: 10.1093/jjco/hyy150.


Corticospinal excitability is modulated by temporal feedback gaps.

Suzuki T, Suzuki M, Hamaguchi T.

Neuroreport. 2018 Dec 12;29(18):1558-1563. doi: 10.1097/WNR.0000000000001148.


A phase II study of NK012, a polymeric micelle formulation of SN-38, in unresectable, metastatic or recurrent colorectal cancer patients.

Hamaguchi T, Tsuji A, Yamaguchi K, Takeda K, Uetake H, Esaki T, Amagai K, Sakai D, Baba H, Kimura M, Matsumura Y, Tsukamoto T.

Cancer Chemother Pharmacol. 2018 Dec;82(6):1021-1029. doi: 10.1007/s00280-018-3693-6. Epub 2018 Oct 4.


Effect of attention bias modification on event-related potentials in patients with irritable bowel syndrome: A preliminary brain function and psycho-behavioral study.

Tayama J, Saigo T, Ogawa S, Takeoka A, Hamaguchi T, Inoue K, Okamura H, Yajima J, Matsudaira K, Fukudo S, Shirabe S.

Neurogastroenterol Motil. 2018 Oct;30(10):e13402. doi: 10.1111/nmo.13402. Epub 2018 Jul 30.


Retrospective Analyses of Systemic Chemotherapy and Cytoreductive Surgery for Patients with Ovarian Metastases from Colorectal Cancer: A Single-Center Experience.

Sekine K, Hamaguchi T, Shoji H, Takashima A, Honma Y, Iwasa S, Kato K, Takahashi K, Kato T, Kanemitsu Y, Boku N.

Oncology. 2018;95(4):220-228. doi: 10.1159/000489665. Epub 2018 Jul 20.


Lateral optical confinement of GaN-based VCSEL using an atomically smooth monolithic curved mirror.

Hamaguchi T, Tanaka M, Mitomo J, Nakajima H, Ito M, Ohara M, Kobayashi N, Fujii K, Watanabe H, Satou S, Koda R, Narui H.

Sci Rep. 2018 Jul 9;8(1):10350. doi: 10.1038/s41598-018-28418-6.


The sulfation code for propagation of neurodegeneration.

Yamada M, Hamaguchi T.

J Biol Chem. 2018 Jul 6;293(27):10841-10842. doi: 10.1074/jbc.H118.003970.


Imaging peritoneal metastasis of gastric cancer with 18F-fluorothymidine positron emission tomography/computed tomography: a proof-of-concept study.

Honma Y, Terauchi T, Tateishi U, Kano D, Nagashima K, Shoji H, Iwasa S, Takashima A, Kato K, Hamaguchi T, Boku N, Shimada Y, Yamada Y.

Br J Radiol. 2018 Sep;91(1089):20180259. doi: 10.1259/bjr.20180259. Epub 2018 Jun 27.


Impairment in toileting behavior after a stroke.

Kawanabe E, Suzuki M, Tanaka S, Sasaki S, Hamaguchi T.

Geriatr Gerontol Int. 2018 Aug;18(8):1166-1172. doi: 10.1111/ggi.13435. Epub 2018 May 17.


Metal artifact reduction by filter-based dual-energy cone-beam computed tomography on a bench-top micro-CBCT system: concept and demonstration.

Iramina H, Hamaguchi T, Nakamura M, Mizowaki T, Kanno I.

J Radiat Res. 2018 Jul 1;59(4):511-520. doi: 10.1093/jrr/rry034.


Nonequivalent modulation of corticospinal excitability by positive and negative outcomes.

Suzuki M, Hamaguchi T, Matsunaga A.

Brain Behav. 2017 Dec 12;8(1):e00862. doi: 10.1002/brb3.862. eCollection 2018 Jan.


Interleukin-6 receptor inhibitor suppresses bone metastases in a breast cancer cell line.

Wakabayashi H, Hamaguchi T, Nagao N, Kato S, Iino T, Nakamura T, Sudo A.

Breast Cancer. 2018 Sep;25(5):566-574. doi: 10.1007/s12282-018-0853-9. Epub 2018 Mar 19.


Prevalence of chronic postsurgical pain after thoracotomy and total knee arthroplasty: a retrospective multicenter study in Japan (Japanese Study Group of Subacute Postoperative Pain).

Sugiyama Y, Iida H, Amaya F, Matsuo K, Matsuoka Y, Kojima K, Matsuno F, Hamaguchi T, Iseki M, Yamaguchi K, Takahashi Y, Hara A, Sugasawa Y, Kawamata M, Tanaka S, Inagaki Y, Otsuki A, Yamazaki M, Ito H.

J Anesth. 2018 Jun;32(3):434-438. doi: 10.1007/s00540-018-2481-0. Epub 2018 Mar 9.


Type of second primary malignancy after achieving complete response by definitive chemoradiation therapy in patients with esophageal squamous cell carcinoma.

Yamaguchi T, Kato K, Nagashima K, Iwasa S, Honma Y, Takashima A, Hamaguchi T, Ito Y, Itami J, Boku N, Higuchi K.

Int J Clin Oncol. 2018 Aug;23(4):652-658. doi: 10.1007/s10147-018-1258-7. Epub 2018 Mar 8.


Update: Dura Mater Graft-Associated Creutzfeldt-Jakob Disease - Japan, 1975-2017.

Ae R, Hamaguchi T, Nakamura Y, Yamada M, Tsukamoto T, Mizusawa H, Belay ED, Schonberger LB.

MMWR Morb Mortal Wkly Rep. 2018 Mar 9;67(9):274-278. doi: 10.15585/mmwr.mm6709a3.


Treatment of a case of severe insulin resistance as a result of a PIK3R1 mutation with a sodium-glucose cotransporter 2 inhibitor.

Hamaguchi T, Hirota Y, Takeuchi T, Nakagawa Y, Matsuoka A, Matsumoto M, Awano H, Iijima K, Cha PC, Satake W, Toda T, Ogawa W.

J Diabetes Investig. 2018 Sep;9(5):1224-1227. doi: 10.1111/jdi.12825. Epub 2018 Mar 25.


Optimization of DARTEL Settings for the Detection of Alzheimer Disease.

Komatsu J, Matsunari I, Samuraki M, Shima K, Noguchi-Shinohara M, Sakai K, Hamaguchi T, Ono K, Matsuda H, Yamada M.

AJNR Am J Neuroradiol. 2018 Feb 1. doi: 10.3174/ajnr.A5509. [Epub ahead of print]


Anxiety, fatigue, and attentional bias toward threat in patients with hematopoietic tumors.

Koizumi K, Tayama J, Ishioka T, Nakamura-Thomas H, Suzuki M, Hara M, Makita S, Hamaguchi T.

PLoS One. 2018 Feb 5;13(2):e0192056. doi: 10.1371/journal.pone.0192056. eCollection 2018.


Biochemical features of genetic Creutzfeldt-Jakob disease with valine-to-isoleucine substitution at codon 180 on the prion protein gene.

Ito Y, Sanjo N, Hizume M, Kobayashi A, Ohgami T, Satoh K, Hamaguchi T, Yamada M, Kitamoto T, Mizusawa H, Yokota T.

Biochem Biophys Res Commun. 2018 Feb 19;496(4):1055-1061. doi: 10.1016/j.bbrc.2018.01.119. Epub 2018 Jan 31.


[Risk Assessment of Chemotherapy for the Elderly Patients with Gastrointestinal Cancer].

Hamaguchi T.

Gan To Kagaku Ryoho. 2018 Jan;45(1):12-15. Japanese.


A retrospective analysis of 5-fluorouracil plus cisplatin as first-line chemotherapy in the recent treatment strategy for patients with metastatic or recurrent esophageal squamous cell carcinoma.

Hiramoto S, Kato K, Shoji H, Okita N, Takashima A, Honma Y, Iwasa S, Hamaguchi T, Yamada Y, Shimada Y, Boku N.

Int J Clin Oncol. 2018 Jun;23(3):466-472. doi: 10.1007/s10147-018-1239-x. Epub 2018 Jan 20.


The peripheral immune status of granulocytic myeloid-derived suppressor cells correlates the survival in advanced gastric cancer patients receiving cisplatin-based chemotherapy.

Shoji H, Tada K, Kitano S, Nishimura T, Shimada Y, Nagashima K, Aoki K, Hiraoka N, Honma Y, Iwasa S, Takashima A, Kato K, Boku N, Honda K, Yamada T, Heike Y, Hamaguchi T.

Oncotarget. 2017 May 30;8(56):95083-95094. doi: 10.18632/oncotarget.18297. eCollection 2017 Nov 10.


The Effect of Ethanol on the Hydrolysis of Ester-Type Drugs by Human Serum Albumin.

Tatsumi A, Inoue S, Hamaguchi T, Iwakawa S.

Biol Pharm Bull. 2018 Feb 1;41(2):277-280. doi: 10.1248/bpb.b17-00680. Epub 2017 Nov 27.


Time-series analysis: variation of anti-acetylcholine receptor antibody titer in myasthenia gravis is related to incidence of Mycoplasma pneumoniae and influenza virus infections.

Iwasa K, Yoshikawa H, Hamaguchi T, Sakai K, Shinohara-Noguchi M, Samuraki M, Takahashi K, Yanase D, Ono K, Ishida C, Yoshita M, Nakamura H, Yamada M.

Neurol Res. 2018 Feb;40(2):102-109. doi: 10.1080/01616412.2017.1407021. Epub 2017 Nov 24.


A Prospective, Multicenter Phase II Study of the Efficacy and Feasibility of 15-minute Panitumumab Infusion Plus Irinotecan for Oxaliplatin- and Irinotecan-refractory, KRAS Wild-type Metastatic Colorectal Cancer (Short Infusion of Panitumumab Trial).

Akiyoshi K, Hamaguchi T, Yoshimura K, Takahashi N, Honma Y, Iwasa S, Takashima A, Kato K, Yamada Y, Onodera H, Takeshita S, Yasui H, Sakai G, Akatsuka S, Ogawa K, Horita Y, Nagai Y, Shimada Y.

Clin Colorectal Cancer. 2018 Mar;17(1):e83-e89. doi: 10.1016/j.clcc.2017.10.004. Epub 2017 Oct 16.


Disentangling the prognostic heterogeneity of stage III colorectal cancer through histologic stromal categorization.

Ueno H, Sekine S, Oshiro T, Kanemitsu Y, Hamaguchi T, Shida D, Takashima A, Ishiguro M, Ito E, Hashiguchi Y, Kondo F, Shimazaki H, Mochizuki S, Kajiwara Y, Shinto E, Yamamoto J, Shimada Y.

Surgery. 2018 Apr;163(4):777-783. doi: 10.1016/j.surg.2017.09.007. Epub 2017 Nov 20.


[III. The Review of JSCCR Guidelines 2016 for the Treatment of Colorectal Cancer].

Miyamoto T, Hamaguchi T.

Gan To Kagaku Ryoho. 2017 Nov;44(11):995-1000. Japanese. No abstract available.


Patterns of Relapse after Definitive Chemoradiotherapy in Stage II/III (Non-T4) Esophageal Squamous Cell Carcinoma.

Sudo K, Kato K, Kuwabara H, Sasaki Y, Takahashi N, Shoji H, Iwasa S, Honma Y, Okita NT, Takashima A, Hamaguchi T, Yamada Y, Ito Y, Itami J, Fukuda T, Tobinai K, Boku N.

Oncology. 2018;94(1):47-54. doi: 10.1159/000480515. Epub 2017 Oct 28.


Capecitabine versus S-1 as adjuvant chemotherapy for patients with stage III colorectal cancer (JCOG0910): an open-label, non-inferiority, randomised, phase 3, multicentre trial.

Hamaguchi T, Shimada Y, Mizusawa J, Kinugasa Y, Kanemitsu Y, Ohue M, Fujii S, Takiguchi N, Yatsuoka T, Takii Y, Ojima H, Masuko H, Kubo Y, Mishima H, Yamaguchi T, Bando H, Sato T, Kato T, Nakamura K, Fukuda H, Moriya Y.

Lancet Gastroenterol Hepatol. 2018 Jan;3(1):47-56. doi: 10.1016/S2468-1253(17)30297-2. Epub 2017 Oct 24.


Coexistence of transthyretin- and Aβ-type cerebral amyloid angiopathy in a patient with hereditary transthyretin V30M amyloidosis.

Sakai K, Asakawa M, Takahashi R, Ishida C, Nakamura R, Hamaguchi T, Ono K, Iwasa K, Yamada M.

J Neurol Sci. 2017 Oct 15;381:144-146. doi: 10.1016/j.jns.2017.08.3240. Epub 2017 Aug 31. No abstract available.


Yokukansankachimpihange increased body weight but not food-incentive motivation in wild-type mice.

Hamaguchi T, Tsutsui-Kimura I, F Tanaka K, Mimura M.

Nagoya J Med Sci. 2017 Aug;79(3):351-362. doi: 10.18999/nagjms.79.3.351.


A phase II study of combination therapy with oral S-1 and cisplatin in elderly patients with advanced gastric cancer.

Sasaki Y, Iwasa S, Okazaki S, Goto M, Kojima Y, Naganuma A, Nagashima K, Nagai Y, Hirano H, Honma Y, Takashima A, Kato K, Hamaguchi T.

Gastric Cancer. 2018 May;21(3):439-445. doi: 10.1007/s10120-017-0753-2. Epub 2017 Aug 1.


Clinical Outcomes of Resectable Esophageal Cancer with Supraclavicular Lymph Node Metastases Treated with Curative Intent.

Honma Y, Hokamura N, Nagashima K, Sudo K, Shoji H, Iwasa S, Takashima A, Kato K, Hamaguchi T, Boku N, Umezawa R, Ito Y, Itami J, Koyanagi K, Igaki H, Tachimori Y.

Anticancer Res. 2017 Jul;37(7):3741-3749.


Discovery of long-range inhibitory signaling to ensure single axon formation.

Takano T, Wu M, Nakamuta S, Naoki H, Ishizawa N, Namba T, Watanabe T, Xu C, Hamaguchi T, Yura Y, Amano M, Hahn KM, Kaibuchi K.

Nat Commun. 2017 Jun 26;8(1):33. doi: 10.1038/s41467-017-00044-2.


Esophageal Metastasis from Rectal Cancer Successfully Treated with Fluorouracil-Based Chemotherapy with Bevacizumab: A Case Report and Review of the Literature.

Watanabe S, Takashima A, Taniguchi H, Tanaka Y, Nakamura S, Okita N, Honma Y, Iwasa S, Kato K, Hamaguchi T, Boku N.

Case Rep Oncol. 2017 May 5;10(2):407-415. doi: 10.1159/000474939. eCollection 2017 May-Aug.


Effect of attention bias modification on brain function and anxiety in patients with irritable bowel syndrome: A preliminary electroencephalogram and psycho-behavioral study.

Tayama J, Saigo T, Ogawa S, Takeoka A, Hamaguchi T, Hayashida M, Fukudo S, Shirabe S.

Neurogastroenterol Motil. 2017 Dec;29(12). doi: 10.1111/nmo.13131. Epub 2017 Jun 14.


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