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Efficacy of aspirin for stage III colorectal cancer: a randomized double-blind placebo-controlled trial (JCOG1503C, EPISODE-III trial).

Miyamoto K, Takashima A, Mizusawa J, Sato Y, Shimada Y, Katayama H, Nakamura K, Shibata T, Fukuda H, Shida D, Kanemitsu Y, Hamaguchi T; Colorectal Cancer Study Group of the Japan Clinical Oncology Group.

Jpn J Clin Oncol. 2019 Oct 1;49(10):985-990. doi: 10.1093/jjco/hyz106.


Differential Effect of Visual and Proprioceptive Stimulation on Corticospinal Output for Reciprocal Muscles.

Suzuki T, Suzuki M, Kanemura N, Hamaguchi T.

Front Integr Neurosci. 2019 Oct 29;13:63. doi: 10.3389/fnint.2019.00063. eCollection 2019.


Acquired cerebral amyloid angiopathy: An emerging concept.

Yamada M, Hamaguchi T, Sakai K.

Prog Mol Biol Transl Sci. 2019;168:85-95. doi: 10.1016/bs.pmbts.2019.05.012. Epub 2019 Jun 18.


Tidy up cryo-EM sample grids with 3D printed tools.

Hamaguchi T, Yonekura K.

J Struct Biol. 2019 Nov 4:107414. doi: 10.1016/j.jsb.2019.107414. [Epub ahead of print]


Temporal trends in prevalence and outcomes of atrial fibrillation in patients undergoing percutaneous coronary intervention.

Morita Y, Hamaguchi T, Yamaji Y, Hayashi H, Nakane E, Haruna Y, Haruna T, Hanyu M, Inoko M.

Clin Cardiol. 2019 Nov 6. doi: 10.1002/clc.23285. [Epub ahead of print]


Geriatric Research Policy: Japan Clinical Oncology Group (JCOG) policy.

Mizutani T, Nakamura K, Fukuda H, Ogawa A, Hamaguchi T, Nagashima F; Geriatric Study Committee/Japan Clinical Oncology Group.

Jpn J Clin Oncol. 2019 Oct 1;49(10):901-910. doi: 10.1093/jjco/hyz093.


Protein Kinase N Promotes Stress-Induced Cardiac Dysfunction Through Phosphorylation of Myocardin-Related Transcription Factor A and Disruption of Its Interaction With Actin.

Sakaguchi T, Takefuji M, Wettschureck N, Hamaguchi T, Amano M, Kato K, Tsuda T, Eguchi S, Ishihama S, Mori Y, Yura Y, Yoshida T, Unno K, Okumura T, Ishii H, Shimizu Y, Bando YK, Ohashi K, Ouchi N, Enomoto A, Offermanns S, Kaibuchi K, Murohara T.

Circulation. 2019 Nov 19;140(21):1737-1752. doi: 10.1161/CIRCULATIONAHA.119.041019. Epub 2019 Sep 30.


Exploration of potential prognostic biomarkers in aflibercept plus FOLFIRI in Japanese patients with metastatic colorectal cancer.

Hamaguchi T, Denda T, Kudo T, Sugimoto N, Ura T, Yamazaki K, Fujii H, Kajiwara T, Nakajima TE, Takahashi S, Otsu S, Komatsu Y, Nagashima F, Moriwaki T, Esaki T, Sato T, Itabashi M, Oki E, Sasaki T, Chiron M, Yoshino T.

Cancer Sci. 2019 Nov;110(11):3565-3572. doi: 10.1111/cas.14198. Epub 2019 Oct 21.


Treatment with Rituximab in the Acute Phase of Relapsing Remitting Multiple Sclerosis: A Case Report.

Shima A, Hamaguchi T, Tada Y, Yamada M.

Intern Med. 2019 Aug 28. doi: 10.2169/internalmedicine.3408-19. [Epub ahead of print]


Relationship between glycated hemoglobin level and duration of hypoglycemia in type 2 diabetes patients treated with sulfonylureas: A multicenter cross-sectional study.

Matsuoka A, Hirota Y, Takeda A, Kishi M, Hashimoto N, Ohara T, Higo S, Yamada H, Nakamura T, Hamaguchi T, Takeuchi T, Nakagawa Y, Okada Y, Sakaguchi K, Ogawa W.

J Diabetes Investig. 2019 Aug 28. doi: 10.1111/jdi.13132. [Epub ahead of print]


Tumor-to-tumor metastasis from appendiceal adenocarcinoma to an ovarian mature teratoma, mimicking malignant transformation of a teratoma: a case report.

Yano M, Katoh T, Hamaguchi T, Kozawa E, Hamada M, Nagata K, Yasuda M.

Diagn Pathol. 2019 Aug 14;14(1):88. doi: 10.1186/s13000-019-0865-6.


Association of Long-Term Treatment by Botulinum Neurotoxins and Occupational Therapy with Subjective Physical Status in Patients with Post-Stroke Hemiplegia.

Hamaguchi T, Abo M, Murata K, Kenmoku M, Yoshizawa I, Ishikawa A, Suzuki M, Nakaya N, Taguchi K.

Toxins (Basel). 2019 Aug 2;11(8). pii: E453. doi: 10.3390/toxins11080453.


Changes in Magnitude and Variability of Corticospinal Excitability During Rewarded Time-Sensitive Behavior.

Suzuki M, Suzuki T, Wang YJ, Hamaguchi T.

Front Behav Neurosci. 2019 Jul 2;13:147. doi: 10.3389/fnbeh.2019.00147. eCollection 2019.


Translational approach to apathy-like behavior in mice: From the practical point of view.

Tanaka KF, Hamaguchi T.

Psychiatry Clin Neurosci. 2019 Nov;73(11):685-689. doi: 10.1111/pcn.12915. Epub 2019 Aug 22. Review.


Efficacy and safety of pemetrexed plus cisplatin as first-line chemotherapy in advanced malignant peritoneal mesothelioma.

Nagata Y, Sawada R, Takashima A, Shoji H, Honma Y, Iwasa S, Amano K, Kato K, Hamaguchi T, Shimada Y, Saruta M, Boku N.

Jpn J Clin Oncol. 2019 Jul 9. pii: hyz104. doi: 10.1093/jjco/hyz104. [Epub ahead of print]


Corticospinal excitability related to reciprocal muscles during the motor preparation period: effect of movement repetition.

Suzuki M, Suzuki T, Tanaka S, Sugawara K, Hamaguchi T.

Neuroreport. 2019 Aug 14;30(12):856-862. doi: 10.1097/WNR.0000000000001288.


Chemoradiotherapy for Local Recurrence of Rectal Cancer: A Single Center Study of 18 Patients.

Watanabe J, Shoji H, Hamaguchi T, Miyamoto T, Hirano H, Iwasa S, Honma Y, Takashima A, Kato K, Ito Y, Itami J, Kanemitsu Y, Boku N.

In Vivo. 2019 Jul-Aug;33(4):1363-1368. doi: 10.21873/invivo.11612.


Gastric mucosal injury and hemorrhage after definitive chemoradiotherapy for locally advanced esophageal cancer.

Monma S, Kato K, Shouji H, Okita N, Takashima A, Honma Y, Iwasa S, Hamaguchi T, Yamada Y, Shimada Y, Boku N, Nagashima K, Ito Y, Itami J.

Esophagus. 2019 Oct;16(4):402-407. doi: 10.1007/s10388-019-00680-1. Epub 2019 Jun 20.


Rosmarinic acid suppresses Alzheimer's disease development by reducing amyloid β aggregation by increasing monoamine secretion.

Hase T, Shishido S, Yamamoto S, Yamashita R, Nukima H, Taira S, Toyoda T, Abe K, Hamaguchi T, Ono K, Noguchi-Shinohara M, Yamada M, Kobayashi S.

Sci Rep. 2019 Jun 18;9(1):8711. doi: 10.1038/s41598-019-45168-1.


Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer.

Hashiguchi Y, Muro K, Saito Y, Ito Y, Ajioka Y, Hamaguchi T, Hasegawa K, Hotta K, Ishida H, Ishiguro M, Ishihara S, Kanemitsu Y, Kinugasa Y, Murofushi K, Nakajima TE, Oka S, Tanaka T, Taniguchi H, Tsuji A, Uehara K, Ueno H, Yamanaka T, Yamazaki K, Yoshida M, Yoshino T, Itabashi M, Sakamaki K, Sano K, Shimada Y, Tanaka S, Uetake H, Yamaguchi S, Yamaguchi N, Kobayashi H, Matsuda K, Kotake K, Sugihara K; Japanese Society for Cancer of the Colon and Rectum.

Int J Clin Oncol. 2019 Jun 15. doi: 10.1007/s10147-019-01485-z. [Epub ahead of print]


Age at onset in genetic prion disease and the design of preventive clinical trials.

Minikel EV, Vallabh SM, Orseth MC, Brandel JP, Haïk S, Laplanche JL, Zerr I, Parchi P, Capellari S, Safar J, Kenny J, Fong JC, Takada LT, Ponto C, Hermann P, Knipper T, Stehmann C, Kitamoto T, Ae R, Hamaguchi T, Sanjo N, Tsukamoto T, Mizusawa H, Collins SJ, Chiesa R, Roiter I, de Pedro-Cuesta J, Calero M, Geschwind MD, Yamada M, Nakamura Y, Mead S.

Neurology. 2019 Jul 9;93(2):e125-e134. doi: 10.1212/WNL.0000000000007745. Epub 2019 Jun 6.


AppNL-G-F/NL-G-F mice overall do not show impaired motivation, but cored amyloid plaques in the striatum are inversely correlated with motivation.

Hamaguchi T, Tsutsui-Kimura I, Mimura M, Saito T, Saido TC, Tanaka KF.

Neurochem Int. 2019 Oct;129:104470. doi: 10.1016/j.neuint.2019.104470. Epub 2019 May 16.


A new cryo-EM system for single particle analysis.

Hamaguchi T, Maki-Yonekura S, Naitow H, Matsuura Y, Ishikawa T, Yonekura K.

J Struct Biol. 2019 Jul 1;207(1):40-48. doi: 10.1016/j.jsb.2019.04.011. Epub 2019 Apr 13.


Nematicidal actions of the marigold exudate α-terthienyl: oxidative stress-inducing compound penetrates nematode hypodermis.

Hamaguchi T, Sato K, Vicente CSL, Hasegawa K.

Biol Open. 2019 Apr 16;8(4). pii: bio038646. doi: 10.1242/bio.038646.


Neuronal intranuclear inclusion disease showing blepharoptosis and positive serum anti-acetylcholine receptor antibody without myasthenia gravis.

Hayashi K, Hamaguchi T, Sakai K, Nakamura K, Wakabayashi K, Shirasaki H, Yamada M.

J Neurol Sci. 2019 May 15;400:119-121. doi: 10.1016/j.jns.2019.03.013. Epub 2019 Mar 16. No abstract available.


Relationship between knee extension strength and gait styles in patients with dementia.

Nakayama N, Suzuki M, Hamaguchi T.

Medicine (Baltimore). 2019 Mar;98(12):e14958. doi: 10.1097/MD.0000000000014958.


Inhibitory Effects of Sodium Alginate on Hepatic Steatosis in Mice Induced by a Methionine- and Choline-deficient Diet.

Kawauchi S, Horibe S, Sasaki N, Tanahashi T, Mizuno S, Hamaguchi T, Rikitake Y.

Mar Drugs. 2019 Feb 9;17(2). pii: E104. doi: 10.3390/md17020104.


Cerebral hemorrhagic stroke associated with cerebral amyloid angiopathy in young adults about 3 decades after neurosurgeries in their infancy.

Hamaguchi T, Komatsu J, Sakai K, Noguchi-Shinohara M, Aoki S, Ikeuchi T, Yamada M.

J Neurol Sci. 2019 Apr 15;399:3-5. doi: 10.1016/j.jns.2019.01.051. Epub 2019 Feb 1. No abstract available.


Identification of novel protein domain for sialyloligosaccharide binding essential to Mycoplasma mobile gliding.

Hamaguchi T, Kawakami M, Furukawa H, Miyata M.

FEMS Microbiol Lett. 2019 Feb 1;366(3). pii: fnz016. doi: 10.1093/femsle/fnz016.


Phase II trial of aflibercept with FOLFIRI as a second-line treatment for Japanese patients with metastatic colorectal cancer.

Denda T, Sakai D, Hamaguchi T, Sugimoto N, Ura T, Yamazaki K, Fujii H, Kajiwara T, Nakajima TE, Takahashi S, Otsu S, Komatsu Y, Nagashima F, Moriwaki T, Esaki T, Sato T, Itabashi M, Oki E, Sasaki T, Sunaga Y, Ziti-Ljajic S, Brillac C, Yoshino T.

Cancer Sci. 2019 Mar;110(3):1032-1043. doi: 10.1111/cas.13943. Epub 2019 Feb 22.


Serum level of octanoic acid predicts the efficacy of chemotherapy for colorectal cancer.

Iemoto T, Nishiumi S, Kobayashi T, Fujigaki S, Hamaguchi T, Kato K, Shoji H, Matsumura Y, Honda K, Yoshida M.

Oncol Lett. 2019 Jan;17(1):831-842. doi: 10.3892/ol.2018.9731. Epub 2018 Nov 19.


Association between UGT1A1 gene polymorphism and safety and efficacy of irinotecan monotherapy as the third-line treatment for advanced gastric cancer.

Yamaguchi T, Iwasa S, Shoji H, Honma Y, Takashima A, Kato K, Hamaguchi T, Higuchi K, Boku N.

Gastric Cancer. 2019 Jul;22(4):778-784. doi: 10.1007/s10120-018-00917-5. Epub 2019 Jan 2.


Effect of switching from conventional continuous subcutaneous insulin infusion to sensor augmented pump therapy on glycemic profile in Japanese patients with type 1 diabetes.

Matsuoka A, Hirota Y, Urai S, Hamaguchi T, Takeuchi T, Miura H, Suematsu N, So A, Nakamura T, Komada H, Okada Y, Sakaguchi K, Ogawa W.

Diabetol Int. 2018 Jan 22;9(3):201-207. doi: 10.1007/s13340-018-0344-4. eCollection 2018 Jul.


Quantification of hydrogen production by intestinal bacteria that are specifically dysregulated in Parkinson's disease.

Suzuki A, Ito M, Hamaguchi T, Mori H, Takeda Y, Baba R, Watanabe T, Kurokawa K, Asakawa S, Hirayama M, Ohno K.

PLoS One. 2018 Dec 26;13(12):e0208313. doi: 10.1371/journal.pone.0208313. eCollection 2018.


A clickable caging group as a new platform for modular caged compounds with improved photochemical properties.

Suzuki AZ, Sekine R, Takeda S, Aikawa R, Shiraishi Y, Hamaguchi T, Okuno H, Tamamura H, Furuta T.

Chem Commun (Camb). 2019 Jan 3;55(4):451-454. doi: 10.1039/c8cc07981a.


[III. Treatment Strategy for Squamous Cell Carcinoma of the Anus].

Hamaguchi T.

Gan To Kagaku Ryoho. 2018 Nov;45(11):1598-1601. Japanese. No abstract available.


Omega-3 polyunsaturated fatty acids and psychological intervention for workers with mild to moderate depression: A double-blind randomized controlled trial.

Tayama J, Ogawa S, Nakaya N, Sone T, Hamaguchi T, Takeoka A, Hamazaki K, Okamura H, Yajima J, Kobayashi M, Hayashida M, Shirabe S.

J Affect Disord. 2019 Feb 15;245:364-370. doi: 10.1016/j.jad.2018.11.039. Epub 2018 Nov 6.


Specific amyloid-β42 deposition in the brain of a Gerstmann-Sträussler-Scheinker disease patient with a P105L mutation on the prion protein gene.

Furukawa F, Sanjo N, Kobayashi A, Hamaguchi T, Yamada M, Kitamoto T, Mizusawa H, Yokota T.

Prion. 2018;12(5-6):315-319. doi: 10.1080/19336896.2018.1541689. Epub 2018 Nov 13.


The prescription rates of glucagon for hypoglycemia by pediatricians and physicians are low in Japan.

Matsumoto M, Awano H, Hirota Y, Nagai M, Bo R, Matsuoka A, Hamaguchi T, Takeuchi T, Nakagawa Y, Ogawa W, Iijima K.

Endocrine. 2019 May;64(2):233-238. doi: 10.1007/s12020-018-1793-z. Epub 2018 Oct 26.


Current clinical practice of adjuvant chemotherapy for patients with 'high-risk' Stage II colorectal cancer in Japan: a questionnaire survey in the JCOG Study Group.

Ishiguro M, Ueno H, Kanemitsu Y, Hamaguchi T, Shida D, Shimada Y; Colorectal Cancer Study Group of Japan Clinical Oncology Group (JCOG).

Jpn J Clin Oncol. 2018 Dec 1;48(12):1109-1112. doi: 10.1093/jjco/hyy150.


Corticospinal excitability is modulated by temporal feedback gaps.

Suzuki T, Suzuki M, Hamaguchi T.

Neuroreport. 2018 Dec 12;29(18):1558-1563. doi: 10.1097/WNR.0000000000001148.


A phase II study of NK012, a polymeric micelle formulation of SN-38, in unresectable, metastatic or recurrent colorectal cancer patients.

Hamaguchi T, Tsuji A, Yamaguchi K, Takeda K, Uetake H, Esaki T, Amagai K, Sakai D, Baba H, Kimura M, Matsumura Y, Tsukamoto T.

Cancer Chemother Pharmacol. 2018 Dec;82(6):1021-1029. doi: 10.1007/s00280-018-3693-6. Epub 2018 Oct 4.


Effect of attention bias modification on event-related potentials in patients with irritable bowel syndrome: A preliminary brain function and psycho-behavioral study.

Tayama J, Saigo T, Ogawa S, Takeoka A, Hamaguchi T, Inoue K, Okamura H, Yajima J, Matsudaira K, Fukudo S, Shirabe S.

Neurogastroenterol Motil. 2018 Oct;30(10):e13402. doi: 10.1111/nmo.13402. Epub 2018 Jul 30.


Retrospective Analyses of Systemic Chemotherapy and Cytoreductive Surgery for Patients with Ovarian Metastases from Colorectal Cancer: A Single-Center Experience.

Sekine K, Hamaguchi T, Shoji H, Takashima A, Honma Y, Iwasa S, Kato K, Takahashi K, Kato T, Kanemitsu Y, Boku N.

Oncology. 2018;95(4):220-228. doi: 10.1159/000489665. Epub 2018 Jul 20.


Lateral optical confinement of GaN-based VCSEL using an atomically smooth monolithic curved mirror.

Hamaguchi T, Tanaka M, Mitomo J, Nakajima H, Ito M, Ohara M, Kobayashi N, Fujii K, Watanabe H, Satou S, Koda R, Narui H.

Sci Rep. 2018 Jul 9;8(1):10350. doi: 10.1038/s41598-018-28418-6.


The sulfation code for propagation of neurodegeneration.

Yamada M, Hamaguchi T.

J Biol Chem. 2018 Jul 6;293(27):10841-10842. doi: 10.1074/jbc.H118.003970.


Imaging peritoneal metastasis of gastric cancer with 18F-fluorothymidine positron emission tomography/computed tomography: a proof-of-concept study.

Honma Y, Terauchi T, Tateishi U, Kano D, Nagashima K, Shoji H, Iwasa S, Takashima A, Kato K, Hamaguchi T, Boku N, Shimada Y, Yamada Y.

Br J Radiol. 2018 Sep;91(1089):20180259. doi: 10.1259/bjr.20180259. Epub 2018 Jun 27.


Japanese Society for Cancer of the Colon and Rectum (JSCCR) Guidelines 2016 for the Clinical Practice of Hereditary Colorectal Cancer (Translated Version).

Ishida H, Yamaguchi T, Tanakaya K, Akagi K, Inoue Y, Kumamoto K, Shimodaira H, Sekine S, Tanaka T, Chino A, Tomita N, Nakajima T, Hasegawa H, Hinoi T, Hirasawa A, Miyakura Y, Murakami Y, Muro K, Ajioka Y, Hashiguchi Y, Ito Y, Saito Y, Hamaguchi T, Ishiguro M, Ishihara S, Kanemitsu Y, Kawano H, Kinugasa Y, Kokudo N, Murofushi K, Nakajima T, Oka S, Sakai Y, Tsuji A, Uehara K, Ueno H, Yamazaki K, Yoshida M, Yoshino T, Boku N, Fujimori T, Itabashi M, Koinuma N, Morita T, Nishimura G, Sakata Y, Shimada Y, Takahashi K, Tanaka S, Tsuruta O, Yamaguchi T, Sugihara K, Watanabe T; Japanese Society for Cancer of the Colon and Rectum.

J Anus Rectum Colon. 2018 May 25;2(Suppl I):S1-S51. doi: 10.23922/jarc.2017-028. eCollection 2018. Review.


Impairment in toileting behavior after a stroke.

Kawanabe E, Suzuki M, Tanaka S, Sasaki S, Hamaguchi T.

Geriatr Gerontol Int. 2018 Aug;18(8):1166-1172. doi: 10.1111/ggi.13435. Epub 2018 May 17.


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