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Items: 1 to 50 of 155

1.

Unification of miRNA and isomiR research: the mirGFF3 format and the mirtop API.

Desvignes T, Loher P, Eilbeck K, Ma J, Urgese G, Fromm B, Sydes J, Aparicio-Puerta E, Barrera V, Espín R, Thibord F, Ros XB, Londin E, Telonis AG, Ficarra E, Friedländer MR, Postlethwait JH, Rigoutsos I, Hackenberg M, Vlachos IS, Halushka MK, Pantano L.

Bioinformatics. 2019 Aug 29. pii: btz675. doi: 10.1093/bioinformatics/btz675. [Epub ahead of print]

PMID:
31504201
2.

Human cardiac myosin light chain 4 (MYL4) mosaic expression patterns vary by sex.

Wang TY, Arking DE, Maleszewski JJ, Fox-Talbot K, Nieuwenhuis TO, Santhanam L, Virmani R, Rosenberg AZ, Halushka MK.

Sci Rep. 2019 Sep 3;9(1):12681. doi: 10.1038/s41598-019-49191-0.

3.

An expanded proteome of cardiac t-tubules.

Cheah JX, Nieuwenhuis TO, Halushka MK.

Cardiovasc Pathol. 2019 Sep - Oct;42:15-20. doi: 10.1016/j.carpath.2019.05.001. Epub 2019 May 24.

PMID:
31202980
4.

Genetic aetiologies should be considered in paediatric cases of acute heart failure presumed to be myocarditis.

Brown EE, McMilllan KN, Halushka MK, Ravekes WJ, Knight M, Crosson JE, Judge DP, Murphy AM.

Cardiol Young. 2019 Jul;29(7):917-921. doi: 10.1017/S1047951119001124. Epub 2019 Jun 14.

PMID:
31198128
5.

Lysyl oxidase-like 2 depletion is protective in age-associated vascular stiffening.

Steppan J, Wang H, Bergman Y, Rauer MJ, Tan S, Jandu S, Nandakumar K, Barreto-Ortiz S, Cole RN, Boronina TN, Zhu W, Halushka MK, An SS, Berkowitz DE, Santhanam L.

Am J Physiol Heart Circ Physiol. 2019 Jul 1;317(1):H49-H59. doi: 10.1152/ajpheart.00670.2018. Epub 2019 Apr 19.

PMID:
31002285
6.

Integrated Transcriptomic and Proteomic Analysis of Primary Human Umbilical Vein Endothelial Cells.

Madugundu AK, Na CH, Nirujogi RS, Renuse S, Kim KP, Burns KH, Wilks C, Langmead B, Ellis SE, Collado-Torres L, Halushka MK, Kim MS, Pandey A.

Proteomics. 2019 Aug;19(15):e1800315. doi: 10.1002/pmic.201800315. Epub 2019 Jun 26.

PMID:
30983154
7.

Ablation Lesion Characterization in Scarred Substrate Assessed Using Cardiac Magnetic Resonance.

Tao S, Guttman MA, Fink S, Elahi H, Patil KD, Ashikaga H, Kolandaivelu AD, Berger RD, Halushka MK, Schmidt EJ, Herzka DA, Halperin HR.

JACC Clin Electrophysiol. 2019 Jan;5(1):91-100. doi: 10.1016/j.jacep.2018.11.001. Epub 2018 Dec 26.

PMID:
30678791
8.

Opportunities for microRNAs in the Crowded Field of Cardiovascular Biomarkers.

Halushka PV, Goodwin AJ, Halushka MK.

Annu Rev Pathol. 2019 Jan 24;14:211-238. doi: 10.1146/annurev-pathmechdis-012418-012827. Epub 2018 Oct 17.

PMID:
30332561
9.

Human and Cow Have Identical miR-21-5p and miR-30a-5p Sequences, Which Are Likely Unsuited to Study Dietary Uptake from Cow Milk.

Fromm B, Tosar JP, Lu Y, Halushka MK, Witwer KW.

J Nutr. 2018 Sep 1;148(9):1506-1507. doi: 10.1093/jn/nxy144. No abstract available.

PMID:
30184228
10.

Seven factors predict a delayed diagnosis of cardiac amyloidosis.

Bishop E, Brown EE, Fajardo J, Barouch LA, Judge DP, Halushka MK.

Amyloid. 2018 Sep;25(3):174-179. doi: 10.1080/13506129.2018.1498782. Epub 2018 Aug 31.

PMID:
30169971
11.

A comprehensive evaluation of the genetic architecture of sudden cardiac arrest.

Ashar FN, Mitchell RN, Albert CM, Newton-Cheh C, Brody JA, Müller-Nurasyid M, Moes A, Meitinger T, Mak A, Huikuri H, Junttila MJ, Goyette P, Pulit SL, Pazoki R, Tanck MW, Blom MT, Zhao X, Havulinna AS, Jabbari R, Glinge C, Tragante V, Escher SA, Chakravarti A, Ehret G, Coresh J, Li M, Prineas RJ, Franco OH, Kwok PY, Lumley T, Dumas F, McKnight B, Rotter JI, Lemaitre RN, Heckbert SR, O'Donnell CJ, Hwang SJ, Tardif JC, VanDenburgh M, Uitterlinden AG, Hofman A, Stricker BHC, de Bakker PIW, Franks PW, Jansson JH, Asselbergs FW, Halushka MK, Maleszewski JJ, Tfelt-Hansen J, Engstrøm T, Salomaa V, Virmani R, Kolodgie F, Wilde AAM, Tan HL, Bezzina CR, Eijgelsheim M, Rioux JD, Jouven X, Kääb S, Psaty BM, Siscovick DS, Arking DE, Sotoodehnia N.

Eur Heart J. 2018 Nov 21;39(44):3961-3969. doi: 10.1093/eurheartj/ehy474.

PMID:
30169657
12.

miRge 2.0 for comprehensive analysis of microRNA sequencing data.

Lu Y, Baras AS, Halushka MK.

BMC Bioinformatics. 2018 Jul 23;19(1):275. doi: 10.1186/s12859-018-2287-y.

13.

Human cardiac cis-regulatory elements, their cognate transcription factors, and regulatory DNA sequence variants.

Lee D, Kapoor A, Safi A, Song L, Halushka MK, Crawford GE, Chakravarti A.

Genome Res. 2018 Oct;28(10):1577-1588. doi: 10.1101/gr.234633.118. Epub 2018 Aug 23.

14.

Marked disparity of microRNA modulation by cGMP-selective PDE5 versus PDE9 inhibitors in heart disease.

Kokkonen-Simon KM, Saberi A, Nakamura T, Ranek MJ, Zhu G, Bedja D, Kuhn M, Halushka MK, Lee DI, Kass DA.

JCI Insight. 2018 Aug 9;3(15). pii: 121739. doi: 10.1172/jci.insight.121739. eCollection 2018 Aug 9.

15.

xMD-miRNA-seq to generate near in vivo miRNA expression estimates in colon epithelial cells.

Rosenberg AZ, Wright C, Fox-Talbot K, Rajpurohit A, Williams C, Porter C, Kovbasnjuk O, McCall MN, Shin JH, Halushka MK.

Sci Rep. 2018 Jun 28;8(1):9783. doi: 10.1038/s41598-018-28198-z.

16.

Cell-type specific expression of oncogenic and tumor suppressive microRNAs in the human prostate and prostate cancer.

Kumar B, Rosenberg AZ, Choi SM, Fox-Talbot K, De Marzo AM, Nonn L, Brennen WN, Marchionni L, Halushka MK, Lupold SE.

Sci Rep. 2018 May 8;8(1):7189. doi: 10.1038/s41598-018-25320-z.

17.

Cardiomyocytes have mosaic patterns of protein expression.

Wang TY, Lee D, Fox-Talbot K, Arking DE, Chakravarti A, Halushka MK.

Cardiovasc Pathol. 2018 May - Jun;34:50-57. doi: 10.1016/j.carpath.2018.03.002. Epub 2018 Mar 24.

18.

Big Strides in Cellular MicroRNA Expression.

Halushka MK, Fromm B, Peterson KJ, McCall MN.

Trends Genet. 2018 Mar;34(3):165-167. doi: 10.1016/j.tig.2017.12.015. Epub 2018 Jan 18. Review.

19.

Right Ventricular Myofilament Functional Differences in Humans With Systemic Sclerosis-Associated Versus Idiopathic Pulmonary Arterial Hypertension.

Hsu S, Kokkonen-Simon KM, Kirk JA, Kolb TM, Damico RL, Mathai SC, Mukherjee M, Shah AA, Wigley FM, Margulies KB, Hassoun PM, Halushka MK, Tedford RJ, Kass DA.

Circulation. 2018 May 29;137(22):2360-2370. doi: 10.1161/CIRCULATIONAHA.117.033147. Epub 2018 Jan 19.

20.

Discovery of noncanonical translation initiation sites through mass spectrometric analysis of protein N termini.

Na CH, Barbhuiya MA, Kim MS, Verbruggen S, Eacker SM, Pletnikova O, Troncoso JC, Halushka MK, Menschaert G, Overall CM, Pandey A.

Genome Res. 2018 Jan;28(1):25-36. doi: 10.1101/gr.226050.117. Epub 2017 Nov 21.

21.

Toward the human cellular microRNAome.

McCall MN, Kim MS, Adil M, Patil AH, Lu Y, Mitchell CJ, Leal-Rojas P, Xu J, Kumar M, Dawson VL, Dawson TM, Baras AS, Rosenberg AZ, Arking DE, Burns KH, Pandey A, Halushka MK.

Genome Res. 2017 Oct;27(10):1769-1781. doi: 10.1101/gr.222067.117. Epub 2017 Sep 6.

22.

Clinical and pathologic implications of extending the spectrum of maternal autoantibodies reactive with ribonucleoproteins associated with cutaneous and now cardiac neonatal lupus from SSA/Ro and SSB/La to U1RNP.

Izmirly PM, Halushka MK, Rosenberg AZ, Whelton S, Rais-Bahrami K, Nath DS, Parton H, Clancy RM, Rasmussen S, Saxena A, Buyon JP.

Autoimmun Rev. 2017 Sep;16(9):980-983. doi: 10.1016/j.autrev.2017.07.013. Epub 2017 Jul 12. Review.

PMID:
28709760
23.

Histopathologic differences partially distinguish syndromic aortic diseases.

Waters KM, Rooper LM, Guajardo A, Halushka MK.

Cardiovasc Pathol. 2017 Sep - Oct;30:6-11. doi: 10.1016/j.carpath.2017.05.008. Epub 2017 Jun 15.

PMID:
28646716
24.

Genetic testing improves identification of transthyretin amyloid (ATTR) subtype in cardiac amyloidosis.

Brown EE, Lee YZJ, Halushka MK, Steenbergen C, Johnson NM, Almansa J, Tedford RJ, Cingolani O, Russell SD, Sharma K, Judge DP.

Amyloid. 2017 Jun;24(2):92-95. doi: 10.1080/13506129.2017.1324418. Epub 2017 May 11.

PMID:
28494620
25.

miRNA Regulation in Gliomas: Usual Suspects in Glial Tumorigenesis and Evolving Clinical Applications.

Ames H, Halushka MK, Rodriguez FJ.

J Neuropathol Exp Neurol. 2017 Apr 1;76(4):246-254. doi: 10.1093/jnen/nlx005. Review.

PMID:
28431179
26.

Ribonucleic artefacts: are some extracellular RNA discoveries driven by cell culture medium components?

Tosar JP, Cayota A, Eitan E, Halushka MK, Witwer KW.

J Extracell Vesicles. 2017 Jan 12;6(1):1272832. doi: 10.1080/20013078.2016.1272832. eCollection 2017. Review.

27.

Exosomal MicroRNA-15a Transfer from the Pancreas Augments Diabetic Complications by Inducing Oxidative Stress.

Kamalden TA, Macgregor-Das AM, Kannan SM, Dunkerly-Eyring B, Khaliddin N, Xu Z, Fusco AP, Yazib SA, Chow RC, Duh EJ, Halushka MK, Steenbergen C, Das S.

Antioxid Redox Signal. 2017 Nov 1;27(13):913-930. doi: 10.1089/ars.2016.6844. Epub 2017 Mar 17.

28.

Tissue Transglutaminase Modulates Vascular Stiffness and Function Through Crosslinking-Dependent and Crosslinking-Independent Functions.

Steppan J, Bergman Y, Viegas K, Armstrong D, Tan S, Wang H, Melucci S, Hori D, Park SY, Barreto SF, Isak A, Jandu S, Flavahan N, Butlin M, An SS, Avolio A, Berkowitz DE, Halushka MK, Santhanam L.

J Am Heart Assoc. 2017 Feb 3;6(2). pii: e004161. doi: 10.1161/JAHA.116.004161.

29.

Baseline Characteristics Predict the Presence of Amyloid on Endomyocardial Biopsy.

Ton VK, Bhonsale A, Gilotra NA, Halushka MK, Steenbergen C, Almansa J, Brown E, Tedford RJ, Wittstein I, Sharma K, Russell SD, Judge DP.

J Card Fail. 2017 Apr;23(4):340-344. doi: 10.1016/j.cardfail.2016.12.006. Epub 2016 Dec 20.

PMID:
28011000
30.

Structural and Functional Correlates of Myocardial T1 Mapping in 321 Patients With Hypertrophic Cardiomyopathy.

Chu LC, Corona-Villalobos CP, Halushka MK, Zhang Y, Pozzessere C, Kamel IR, Pozios I, Van Der Geest RJ, Gai N, Abraham RM, Abraham TP, Bluemke DA, Zimmerman SL.

J Comput Assist Tomogr. 2017 Jul/Aug;41(4):653-660. doi: 10.1097/RCT.0000000000000564.

PMID:
27997439
31.

Toward the promise of microRNAs - Enhancing reproducibility and rigor in microRNA research.

Witwer KW, Halushka MK.

RNA Biol. 2016 Nov;13(11):1103-1116. Epub 2016 Sep 19. Review.

32.

Heart failure therapies: new strategies for old treatments and new treatments for old strategies.

Halushka MK, Mitchell RN, Padera RF.

Cardiovasc Pathol. 2016 Nov - Dec;25(6):503-511. doi: 10.1016/j.carpath.2016.08.008. Epub 2016 Aug 29. Review.

PMID:
27619734
33.

Outcomes and predictors of recovery in acute-onset cardiomyopathy: A single-center experience of patients undergoing endomyocardial biopsy for new heart failure.

Gilotra NA, Bennett MK, Shpigel A, Ahmed HM, Rao S, Dunn JM, Harrington C, Freitag TB, Halushka MK, Russell SD.

Am Heart J. 2016 Sep;179:116-26. doi: 10.1016/j.ahj.2016.06.019. Epub 2016 Jul 5.

PMID:
27595686
34.

Complex Sources of Variation in Tissue Expression Data: Analysis of the GTEx Lung Transcriptome.

McCall MN, Illei PB, Halushka MK.

Am J Hum Genet. 2016 Sep 1;99(3):624-635. doi: 10.1016/j.ajhg.2016.07.007.

35.

Galectin-3 and Risk of Heart Failure and Death in Blacks and Whites.

McEvoy JW, Chen Y, Halushka MK, Christenson E, Ballantyne CM, Blumenthal RS, Christenson RH, Selvin E.

J Am Heart Assoc. 2016 May 13;5(5). pii: e003079. doi: 10.1161/JAHA.115.003079.

36.

Enrichment of Scleroderma Vascular Disease-Associated Autoantigens in Endothelial Lineage Cells.

McMahan ZH, Cottrell TR, Wigley FM, Antiochos B, Zambidis ET, Park TS, Halushka MK, Gutierrez-Alamillo L, Cimbro R, Rosen A, Casciola-Rosen L.

Arthritis Rheumatol. 2016 Oct;68(10):2540-9. doi: 10.1002/art.39743.

37.

Surgical repair of aortic dissection 16 years post-Ross procedure.

Myers MR, Magruder JT, Crawford TC, Grimm JC, Halushka MK, Baumgartner WA, Cameron DE.

J Surg Case Rep. 2016 May 2;2016(4). pii: rjw059. doi: 10.1093/jscr/rjw059.

38.

Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association For European Cardiovascular Pathology: II. Noninflammatory degenerative diseases - nomenclature and diagnostic criteria.

Halushka MK, Angelini A, Bartoloni G, Basso C, Batoroeva L, Bruneval P, Buja LM, Butany J, d'Amati G, Fallon JT, Gallagher PJ, Gittenberger-de Groot AC, Gouveia RH, Kholova I, Kelly KL, Leone O, Litovsky SH, Maleszewski JJ, Miller DV, Mitchell RN, Preston SD, Pucci A, Radio SJ, Rodriguez ER, Sheppard MN, Stone JR, Suvarna SK, Tan CD, Thiene G, Veinot JP, van der Wal AC.

Cardiovasc Pathol. 2016 May-Jun;25(3):247-257. doi: 10.1016/j.carpath.2016.03.002. Epub 2016 Mar 12. Review.

PMID:
27031798
39.

Utilization of HPASubC for the Identification of Sinusoid-Specific Proteins in the Liver.

Anene DF, Rosenberg AZ, Kleiner DE, Cornish TC, Halushka MK.

J Proteome Res. 2016 May 6;15(5):1623-9. doi: 10.1021/acs.jproteome.6b00073. Epub 2016 Mar 29.

PMID:
27005832
40.

A benchmark for microRNA quantification algorithms using the OpenArray platform.

McCall MN, Baras AS, Crits-Christoph A, Ingersoll R, McAlexander MA, Witwer KW, Halushka MK.

BMC Bioinformatics. 2016 Mar 22;17:138. doi: 10.1186/s12859-016-0987-8.

41.

MicroRNA-144 is unlikely to play a role in bronchiolitis obliterans syndrome.

Halushka MK.

J Heart Lung Transplant. 2016 Apr;35(4):543. doi: 10.1016/j.healun.2016.01.008. Epub 2016 Jan 14. No abstract available.

PMID:
26874429
42.

Lack of Relationship Between Serum Cardiac Troponin I Level and Giant Cell Myocarditis Diagnosis and Outcomes.

Gilotra NA, Minkove N, Bennett MK, Tedford RJ, Steenbergen C, Judge DP, Halushka MK, Russell SD.

J Card Fail. 2016 Jul;22(7):583-5. doi: 10.1016/j.cardfail.2015.12.022. Epub 2016 Jan 6. No abstract available.

PMID:
26768222
43.

miRge - A Multiplexed Method of Processing Small RNA-Seq Data to Determine MicroRNA Entropy.

Baras AS, Mitchell CJ, Myers JR, Gupta S, Weng LC, Ashton JM, Cornish TC, Pandey A, Halushka MK.

PLoS One. 2015 Nov 16;10(11):e0143066. doi: 10.1371/journal.pone.0143066. eCollection 2015.

44.

Soluble receptor for advanced glycation end products and the risk for incident heart failure: The Atherosclerosis Risk in Communities Study.

Lazo M, Halushka MK, Shen L, Maruthur N, Rebholz CM, Rawlings AM, Hoogeveen RC, Brinkley TE, Ballantyne CM, Astor BC, Selvin E.

Am Heart J. 2015 Nov;170(5):961-7. doi: 10.1016/j.ahj.2015.08.008. Epub 2015 Aug 14.

45.

Targeting downstream transcription factors and epigenetic modifications following Toll-like receptor 7/8 ligation to forestall tissue injury in anti-Ro60 associated heart block.

Clancy RM, Markham AJ, Reed JH, Blumenberg M, Halushka MK, Buyon JP.

J Autoimmun. 2016 Feb;67:36-45. doi: 10.1016/j.jaut.2015.09.003. Epub 2015 Oct 1.

46.

HPASubC: A suite of tools for user subclassification of human protein atlas tissue images.

Cornish TC, Chakravarti A, Kapoor A, Halushka MK.

J Pathol Inform. 2015 Jun 23;6:36. doi: 10.4103/2153-3539.159213. eCollection 2015.

47.

Cardiovascular pathologies in mucopolysaccharidosis type VII (Sly Syndrome).

Gniadek TJ, Singer N, Barker NJ, Spevak PJ, Crain BJ, Valle D, Halushka MK.

Cardiovasc Pathol. 2015 Sep-Oct;24(5):322-6. doi: 10.1016/j.carpath.2015.06.001. Epub 2015 Jun 19.

PMID:
26141114
48.

Citrullination of myofilament proteins in heart failure.

Fert-Bober J, Giles JT, Holewinski RJ, Kirk JA, Uhrigshardt H, Crowgey EL, Andrade F, Bingham CO 3rd, Park JK, Halushka MK, Kass DA, Bathon JM, Van Eyk JE.

Cardiovasc Res. 2015 Nov 1;108(2):232-42. doi: 10.1093/cvr/cvv185. Epub 2015 Jun 25.

49.

Genetics of Plasma Soluble Receptor for Advanced Glycation End-Products and Cardiovascular Outcomes in a Community-based Population: Results from the Atherosclerosis Risk in Communities Study.

Maruthur NM, Li M, Halushka MK, Astor BC, Pankow JS, Boerwinkle E, Coresh J, Selvin E, Kao WH.

PLoS One. 2015 Jun 17;10(6):e0128452. doi: 10.1371/journal.pone.0128452. eCollection 2015.

50.

Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases.

Stone JR, Bruneval P, Angelini A, Bartoloni G, Basso C, Batoroeva L, Buja LM, Butany J, d'Amati G, Fallon JT, Gittenberger-de Groot AC, Gouveia RH, Halushka MK, Kelly KL, Kholova I, Leone O, Litovsky SH, Maleszewski JJ, Miller DV, Mitchell RN, Preston SD, Pucci A, Radio SJ, Rodriguez ER, Sheppard MN, Suvarna SK, Tan CD, Thiene G, van der Wal AC, Veinot JP.

Cardiovasc Pathol. 2015 Sep-Oct;24(5):267-78. doi: 10.1016/j.carpath.2015.05.001. Epub 2015 May 16. Review.

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