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Items: 44


Lysine specific demethylase 1 inactivation enhances differentiation and promotes cytotoxic response when combined with all-trans retinoic acid in acute myeloid leukemia across subtypes.

Smitheman KN, Severson TM, Rajapurkar SR, McCabe MT, Karpinich N, Foley J, Pappalardi MB, Hughes A, Halsey W, Thomas E, Traini C, Federowicz KE, Laraio J, Mobegi F, Ferron-Brady G, Prinjha RK, Carpenter CL, Kruger RG, Wessels L, Mohammad HP.

Haematologica. 2019 Jun;104(6):1156-1167. doi: 10.3324/haematol.2018.199190. Epub 2018 Dec 4.


Tumor-immune profiling of murine syngeneic tumor models as a framework to guide mechanistic studies and predict therapy response in distinct tumor microenvironments.

Yu JW, Bhattacharya S, Yanamandra N, Kilian D, Shi H, Yadavilli S, Katlinskaya Y, Kaczynski H, Conner M, Benson W, Hahn A, Seestaller-Wehr L, Bi M, Vitali NJ, Tsvetkov L, Halsey W, Hughes A, Traini C, Zhou H, Jing J, Lee T, Figueroa DJ, Brett S, Hopson CB, Smothers JF, Hoos A, Srinivasan R.

PLoS One. 2018 Nov 2;13(11):e0206223. doi: 10.1371/journal.pone.0206223. eCollection 2018.


Targeting Bromodomain and Extra-Terminal (BET) Family Proteins in Castration-Resistant Prostate Cancer (CRPC).

Welti J, Sharp A, Yuan W, Dolling D, Nava Rodrigues D, Figueiredo I, Gil V, Neeb A, Clarke M, Seed G, Crespo M, Sumanasuriya S, Ning J, Knight E, Francis JC, Hughes A, Halsey WS, Paschalis A, Mani RS, Raj GV, Plymate SR, Carreira S, Boysen G, Chinnaiyan AM, Swain A, de Bono JS; International SU2C/PCF Prostate Cancer Dream Team.

Clin Cancer Res. 2018 Jul 1;24(13):3149-3162. doi: 10.1158/1078-0432.CCR-17-3571. Epub 2018 Mar 19.


BRD4 Promotes DNA Repair and Mediates the Formation of TMPRSS2-ERG Gene Rearrangements in Prostate Cancer.

Li X, Baek G, Ramanand SG, Sharp A, Gao Y, Yuan W, Welti J, Rodrigues DN, Dolling D, Figueiredo I, Sumanasuriya S, Crespo M, Aslam A, Li R, Yin Y, Mukherjee B, Kanchwala M, Hughes AM, Halsey WS, Chiang CM, Xing C, Raj GV, Burma S, de Bono J, Mani RS.

Cell Rep. 2018 Jan 16;22(3):796-808. doi: 10.1016/j.celrep.2017.12.078.


Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress.

Qin P, Arabacilar P, Bernard RE, Bao W, Olzinski AR, Guo Y, Lal H, Eisennagel SH, Platchek MC, Xie W, Del Rosario J, Nayal M, Lu Q, Roethke T, Schnackenberg CG, Wright F, Quaile MP, Halsey WS, Hughes AM, Sathe GM, Livi GP, Kirkpatrick RB, Qu XA, Rajpal DK, Faelth Savitski M, Bantscheff M, Joberty G, Bergamini G, Force TL, Gatto GJ Jr, Hu E, Willette RN.

J Am Heart Assoc. 2017 May 9;6(5). pii: e004453. doi: 10.1161/JAHA.116.004453.


Characterization of Gene Expression Phenotype in Amyotrophic Lateral Sclerosis Monocytes.

Zhao W, Beers DR, Hooten KG, Sieglaff DH, Zhang A, Kalyana-Sundaram S, Traini CM, Halsey WS, Hughes AM, Sathe GM, Livi GP, Fan GH, Appel SH.

JAMA Neurol. 2017 Jun 1;74(6):677-685. doi: 10.1001/jamaneurol.2017.0357.


A687V EZH2 is a driver of histone H3 lysine 27 (H3K27) hypertrimethylation.

Ott HM, Graves AP, Pappalardi MB, Huddleston M, Halsey WS, Hughes AM, Groy A, Dul E, Jiang Y, Bai Y, Annan R, Verma SK, Knight SD, Kruger RG, Dhanak D, Schwartz B, Tummino PJ, Creasy CL, McCabe MT.

Mol Cancer Ther. 2014 Dec;13(12):3062-73. doi: 10.1158/1535-7163.MCT-13-0876. Epub 2014 Sep 24.


Silicone-based endotracheal tube causing airway obstruction and pneumothorax.

Capra GG, Shah AN, Moore JD, Halsey WS, Lujan E.

Arch Otolaryngol Head Neck Surg. 2012 Jun;138(6):588-91. doi: 10.1001/archoto.2012.688. No abstract available.


Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27).

McCabe MT, Graves AP, Ganji G, Diaz E, Halsey WS, Jiang Y, Smitheman KN, Ott HM, Pappalardi MB, Allen KE, Chen SB, Della Pietra A 3rd, Dul E, Hughes AM, Gilbert SA, Thrall SH, Tummino PJ, Kruger RG, Brandt M, Schwartz B, Creasy CL.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2989-94. doi: 10.1073/pnas.1116418109. Epub 2012 Feb 8.


Deep sequencing of gastric carcinoma reveals somatic mutations relevant to personalized medicine.

Holbrook JD, Parker JS, Gallagher KT, Halsey WS, Hughes AM, Weigman VJ, Lebowitz PF, Kumar R.

J Transl Med. 2011 Jul 25;9:119. doi: 10.1186/1479-5876-9-119.


Sensitivity of cancer cells to Plk1 inhibitor GSK461364A is associated with loss of p53 function and chromosome instability.

Degenhardt Y, Greshock J, Laquerre S, Gilmartin AG, Jing J, Richter M, Zhang X, Bleam M, Halsey W, Hughes A, Moy C, Liu-Sullivan N, Powers S, Bachman K, Jackson J, Weber B, Wooster R.

Mol Cancer Ther. 2010 Jul;9(7):2079-89. doi: 10.1158/1535-7163.MCT-10-0095. Epub 2010 Jun 22.


Molecular evolutionary analysis of cancer cell lines.

Zhang Y, Italia MJ, Auger KR, Halsey WS, Van Horn SF, Sathe GM, Magid-Slav M, Brown JR, Holbrook JD.

Mol Cancer Ther. 2010 Feb;9(2):279-91. doi: 10.1158/1535-7163.MCT-09-0508. Epub 2010 Feb 2.


Novel mechanism of lapatinib resistance in HER2-positive breast tumor cells: activation of AXL.

Liu L, Greger J, Shi H, Liu Y, Greshock J, Annan R, Halsey W, Sathe GM, Martin AM, Gilmer TM.

Cancer Res. 2009 Sep 1;69(17):6871-8. doi: 10.1158/0008-5472.CAN-08-4490. Epub 2009 Aug 11.


Integrating a high-force optical trap with gold nanoposts and a robust gold-DNA bond.

Paik DH, Seol Y, Halsey WA, Perkins TT.

Nano Lett. 2009 Aug;9(8):2978-83. doi: 10.1021/nl901404s.


Comparative analysis of the complete nucleotide sequences of measles, mumps, and rubella strain genomes contained in Priorix-Tetra and ProQuad live attenuated combined vaccines.

Tillieux SL, Halsey WS, Sathe GM, Vassilev V.

Vaccine. 2009 Apr 6;27(16):2265-73. doi: 10.1016/j.vaccine.2009.01.112. Epub 2009 Jan 31.


Potent inhibitors of HIV-1 integrase display a two-step, slow-binding inhibition mechanism which is absent in a drug-resistant T66I/M154I mutant.

Garvey EP, Schwartz B, Gartland MJ, Lang S, Halsey W, Sathe G, Carter HL 3rd, Weaver KL.

Biochemistry. 2009 Feb 24;48(7):1644-53. doi: 10.1021/bi802141y.


Complete DNA sequences of two oka strain varicella-zoster virus genomes.

Tillieux SL, Halsey WS, Thomas ES, Voycik JJ, Sathe GM, Vassilev V.

J Virol. 2008 Nov;82(22):11023-44. doi: 10.1128/JVI.00777-08. Epub 2008 Sep 10.


Temporal and spatial distribution of clonal complexes of Streptococcus pneumoniae isolates resistant to multiple classes of antibiotics in Belgium, 1997 to 2004.

Amrine-Madsen H, Van Eldere J, Mera RM, Miller LA, Poupard JA, Thomas ES, Halsey WS, Becker JA, O'Hara FP.

Antimicrob Agents Chemother. 2008 Sep;52(9):3216-20. doi: 10.1128/AAC.00358-08. Epub 2008 Jun 23.


TFIIA changes the conformation of the DNA in TBP/TATA complexes and increases their kinetic stability.

Hieb AR, Halsey WA, Betterton MD, Perkins TT, Kugel JF, Goodrich JA.

J Mol Biol. 2007 Sep 21;372(3):619-32. Epub 2007 Jun 29.


Stabilization of an optical microscope to 0.1 nm in three dimensions.

Carter AR, King GM, Ulrich TA, Halsey W, Alchenberger D, Perkins TT.

Appl Opt. 2007 Jan 20;46(3):421-7.


An endoscopic view of a wireless pH-monitoring capsule.

Belafsky PC, Halsey W.

Ear Nose Throat J. 2003 Apr;82(4):254. No abstract available.


Cervical esophageal foreign body.

Belafsky PC, Halsey WS, Postma GN, Koufman JA.

Ear Nose Throat J. 2003 Jan;82(1):24. No abstract available.


Distal esophageal meat impaction.

Belafsky PC, Halsey WS, Postma GN, Koufman JA.

Ear Nose Throat J. 2002 Oct;81(10):702. No abstract available.


Assessing the contribution of the herpes simplex virus DNA polymerase to spontaneous mutations.

Duffy KE, Quail MR, Nguyen TT, Wittrock RJ, Bartus JO, Halsey WM, Leary JJ, Bacon TH, Sarisky RT.

BMC Infect Dis. 2002 May 7;2:7.


Absence of rapid selection for acyclovir or penciclovir resistance following suboptimal oral prodrug therapy of HSV-infected mice.

Sarisky RT, Bartus HR, Dennis SA, Quail MR, Nguyen TT, Wittrock RJ, Halsey WS, Bacon TH, Leary JJ, Sutton D.

BMC Infect Dis. 2001;1:24. Epub 2001 Dec 10.


Identification and initial characterization of 5000 expressed sequenced tags (ESTs) each from adult human normal and osteoarthritic cartilage cDNA libraries.

Kumar S, Connor JR, Dodds RA, Halsey W, Van Horn M, Mao J, Sathe G, Mui P, Agarwal P, Badger AM, Lee JC, Gowen M, Lark MW.

Osteoarthritis Cartilage. 2001 Oct;9(7):641-53.


Characterization of herpes simplex viruses selected in culture for resistance to penciclovir or acyclovir.

Sarisky RT, Quail MR, Clark PE, Nguyen TT, Halsey WS, Wittrock RJ, O'Leary Bartus J, Van Horn MM, Sathe GM, Van Horn S, Kelly MD, Bacon TH, Leary JJ.

J Virol. 2001 Feb;75(4):1761-9.


Rapid isolation of tissue-specific genes from rat kidney.

Hu E, Chen Z, Fredrickson TA, Spurr N, Gentle S, Sims M, Zhu Y, Halsey W, Van Horn S, Mao J, Sathe GM, Brooks DP.

Exp Nephrol. 2001 Mar-Apr;9(2):156-64.


Identification of a novel kidney-specific gene downregulated in acute ischemic renal failure.

Hu E, Chen Z, Fredrickson T, Gellai M, Jugus M, Contino L, Spurr N, Sims M, Halsey W, Van Horn S, Mao J, Sathe G, Brooks D.

Am J Physiol Renal Physiol. 2000 Sep;279(3):F426-39. Erratum in: Am J Physiol Renal Physiol 2001 Jun;280(6):section F following table of contents. Am J Physiol Renal Physiol 2001 Apr;280(4):section F following table of contents.


Comparison of a maedi-visna virus CA-TM fusion protein ELISA with other assays for detecting sheep infected with North American ovine lentivirus strains.

DeMartini JC, Halsey W, Boshoff C, York D, Howell MD.

Vet Immunol Immunopathol. 1999 Oct 1;71(1):29-40.


Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor.

Sarau HM, Ames RS, Chambers J, Ellis C, Elshourbagy N, Foley JJ, Schmidt DB, Muccitelli RM, Jenkins O, Murdock PR, Herrity NC, Halsey W, Sathe G, Muir AI, Nuthulaganti P, Dytko GM, Buckley PT, Wilson S, Bergsma DJ, Hay DW.

Mol Pharmacol. 1999 Sep;56(3):657-63.


Analysis of sheep T-cell receptor beta-chain heterogeneity.

Halsey WA Jr, Palmer BE, DeMartini JC, Howell MD.

Immunogenetics. 1999 Mar;49(3):206-14. Erratum in: Immunogenetics. 1999 May; 49(6):594.


Multifaceted inhibition of anti-tumour immune mechanisms by soluble tumour necrosis factor receptor type I.

Selinsky CL, Boroughs KL, Halsey WA Jr, Howell MD.

Immunology. 1998 May;94(1):88-93.


Mechanisms of oxidant-mediated cell injury. The glycolytic and mitochondrial pathways of ADP phosphorylation are major intracellular targets inactivated by hydrogen peroxide.

Hyslop PA, Hinshaw DB, Halsey WA Jr, Schraufstätter IU, Sauerheber RD, Spragg RG, Jackson JH, Cochrane CG.

J Biol Chem. 1988 Feb 5;263(4):1665-75.


In vitro models for the study of oxidant-induced injury of cells in inflammation.

Schraufstätter IU, Halsey WA Jr, Hyslop PA, Cochrane CG.

Methods Enzymol. 1988;163:328-39. No abstract available.


Experimental pulmonary inflammatory injury in the monkey.

Revak SD, Rice CL, Schraufstätter IU, Halsey WA Jr, Bohl BP, Clancy RM, Cochrane CG.

J Clin Invest. 1985 Sep;76(3):1182-92.


The two-layer rhytidectomy.

Kamer FM, Halsey W.

Arch Otolaryngol. 1981 Jul;107(7):450-3.


Protection of the carotid artery in radical neck dissection.

Reed GF, Halsey WS.

Laryngoscope. 1975 Aug;85(8):1353-8. No abstract available.


Postoperative problems of tracheal resection.

Rabuzzi DD, Halsey WS, Ikins PM, Reed GF.

Laryngoscope. 1973 Apr;83(4):568-75. No abstract available.


Echinococcal cyst of spleen.

Gregg RO, Halsey WS.

N Y State J Med. 1973 Mar 1;73(5):693-4. No abstract available.


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