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Items: 1 to 50 of 70

1.

Automated Computational Detection, Quantitation, and Mapping of Mitosis in Whole-Slide Images for Clinically Actionable Surgical Pathology Decision Support.

Puri M, Hoover SB, Hewitt SM, Wei BR, Adissu HA, Halsey CHC, Beck J, Bradley C, Cramer SD, Durham AC, Esplin DG, Frank C, Lyle LT, McGill LD, Sánchez MD, Schaffer PA, Traslavina RP, Buza E, Yang HH, Lee MP, Dwyer JE, Simpson RM.

J Pathol Inform. 2019 Feb 7;10:4. doi: 10.4103/jpi.jpi_59_18. eCollection 2019.

2.

Glucocorticoids and selumetinib are highly synergistic in RAS pathway mutated childhood acute lymphoblastic leukemia through upregulation of BIM.

Matheson EC, Thomas H, Case M, Blair H, Jackson RK, Masic D, Veal G, Halsey C, Newell DR, Vormoor J, Irving JAE.

Haematologica. 2019 Jan 17. pii: haematol.2017.185975. doi: 10.3324/haematol.2017.185975. [Epub ahead of print]

3.

Challenging "privileged" stereotypes - Leukemic blasts and the central nervous system.

Halsey C.

Leuk Res. 2018 Oct;73:76-77. doi: 10.1016/j.leukres.2018.08.013. Epub 2018 Sep 11. No abstract available.

PMID:
30243134
4.

Targeting quiescent leukemic stem cells using second generation autophagy inhibitors.

Baquero P, Dawson A, Mukhopadhyay A, Kuntz EM, Mitchell R, Olivares O, Ianniciello A, Scott MT, Dunn K, Nicastri MC, Winkler JD, Michie AM, Ryan KM, Halsey C, Gottlieb E, Keaney EP, Murphy LO, Amaravadi RK, Holyoake TL, Helgason GV.

Leukemia. 2019 Apr;33(4):981-994. doi: 10.1038/s41375-018-0252-4. Epub 2018 Sep 5.

5.

IL7R is associated with CNS infiltration and relapse in pediatric B-cell precursor acute lymphoblastic leukemia.

Alsadeq A, Lenk L, Vadakumchery A, Cousins A, Vokuhl C, Khadour A, Vogiatzi F, Seyfried F, Meyer LH, Cario G, Hobeika E, Debatin KM, Halsey C, Schrappe M, Schewe DM, Jumaa H.

Blood. 2018 Oct 11;132(15):1614-1617. doi: 10.1182/blood-2018-04-844209. Epub 2018 Aug 28. No abstract available.

6.

The Use of Ommaya Reservoirs to Deliver Central Nervous System-Directed Chemotherapy in Childhood Acute Lymphoblastic Leukaemia.

Wilson R, Osborne C, Halsey C.

Paediatr Drugs. 2018 Aug;20(4):293-301. doi: 10.1007/s40272-018-0298-9. Review.

PMID:
29850985
7.

Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21.

Sinclair PB, Blair HH, Ryan SL, Buechler L, Cheng J, Clayton J, Hanna R, Hollern S, Hawking Z, Bashton M, Schwab CJ, Jones L, Russell LJ, Marr H, Carey P, Halsey C, Heidenreich O, Moorman AV, Harrison CJ.

Haematologica. 2018 Apr;103(4):634-644. doi: 10.3324/haematol.2017.172304. Epub 2018 Feb 15.

8.

Comment on: "Successful use of nitrous oxide during lumbar punctures: A call for nitrous oxide in pediatric oncology clinics".

Forster V, Escherich G, Halsey C.

Pediatr Blood Cancer. 2018 May;65(5):e26930. doi: 10.1002/pbc.26930. Epub 2017 Dec 29. No abstract available.

PMID:
29286566
9.

High throughput sequencing in acute lymphoblastic leukemia reveals clonal architecture of central nervous system and bone marrow compartments.

Bartram J, Goulden N, Wright G, Adams S, Brooks T, Edwards D, Inglott S, Yousafzai Y, Hubank M, Halsey C.

Haematologica. 2018 Mar;103(3):e110-e114. doi: 10.3324/haematol.2017.174987. Epub 2017 Dec 7. No abstract available.

10.

The arginine metabolome in acute lymphoblastic leukemia can be targeted by the pegylated-recombinant arginase I BCT-100.

De Santo C, Booth S, Vardon A, Cousins A, Tubb V, Perry T, Noyvert B, Beggs A, Ng M, Halsey C, Kearns P, Cheng P, Mussai F.

Int J Cancer. 2018 Apr 1;142(7):1490-1502. doi: 10.1002/ijc.31170. Epub 2017 Dec 26.

11.

Reply: Methotrexate neurotoxicity due to drug interactions: an inadequate folinic acid effect.

Forster VJ, van Delft FW, Baird SF, Mair S, Skinner R, Halsey C.

Cancer Chemother Pharmacol. 2017 Apr;79(4):841-842. doi: 10.1007/s00280-017-3270-4. Epub 2017 Mar 13. No abstract available.

PMID:
28289862
12.

Amino Acid Catabolism in Staphylococcus aureus and the Function of Carbon Catabolite Repression.

Halsey CR, Lei S, Wax JK, Lehman MK, Nuxoll AS, Steinke L, Sadykov M, Powers R, Fey PD.

MBio. 2017 Feb 14;8(1). pii: e01434-16. doi: 10.1128/mBio.01434-16.

13.

Expression of Phosphorylated KIT in Canine Mast Cell Tumor.

Halsey CHC, Thamm DH, Weishaar KM, Burton JH, Charles JB, Gustafson DL, Avery AC, Ehrhart EJ.

Vet Pathol. 2017 May;54(3):387-394. doi: 10.1177/0300985816688943. Epub 2017 Jan 27.

PMID:
28129097
14.

Upregulation of Glucose-Regulated Protein 78 in Metastatic Cancer Cells Is Necessary for Lung Metastasis Progression.

Lizardo MM, Morrow JJ, Miller TE, Hong ES, Ren L, Mendoza A, Halsey CH, Scacheri PC, Helman LJ, Khanna C.

Neoplasia. 2016 Oct 28;18(11):699-710. doi: 10.1016/j.neo.2016.09.001. [Epub ahead of print]

15.

Drug interactions may be important risk factors for methotrexate neurotoxicity, particularly in pediatric leukemia patients.

Forster VJ, van Delft FW, Baird SF, Mair S, Skinner R, Halsey C.

Cancer Chemother Pharmacol. 2016 Nov;78(5):1093-1096. Epub 2016 Sep 22.

16.

CARMA1 is a novel regulator of T-ALL disease and leukemic cell migration to the CNS.

Oruganti SR, Torres DJ, Krebsbach S, Asperti-Boursin F, Winters J, Matlawska-Wasowska K, Winter SS, Halsey C, Cannon JL.

Leukemia. 2017 Jan;31(1):255-258. doi: 10.1038/leu.2016.272. Epub 2016 Oct 4. No abstract available.

17.

MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload.

Liu JC, Liu J, Holmström KM, Menazza S, Parks RJ, Fergusson MM, Yu ZX, Springer DA, Halsey C, Liu C, Murphy E, Finkel T.

Cell Rep. 2016 Aug 9;16(6):1561-1573. doi: 10.1016/j.celrep.2016.07.011. Epub 2016 Jul 28.

18.

Synergistic targeted inhibition of MEK and dual PI3K/mTOR diminishes viability and inhibits tumor growth of canine melanoma underscoring its utility as a preclinical model for human mucosal melanoma.

Wei BR, Michael HT, Halsey CH, Peer CJ, Adhikari A, Dwyer JE, Hoover SB, El Meskini R, Kozlov S, Weaver Ohler Z, Figg WD, Merlino G, Simpson RM.

Pigment Cell Melanoma Res. 2016 Nov;29(6):643-655. doi: 10.1111/pcmr.12512. Epub 2016 Sep 22.

19.

Use of dofetilide in adult patients with atrial arrhythmias and congenital heart disease: A PACES collaborative study.

El-Assaad I, Al-Kindi SG, Abraham J, Sanatani S, Bradley DJ, Halsey C, Law IH, Balaji S, Shetty I, Aziz PF.

Heart Rhythm. 2016 Oct;13(10):2034-9. doi: 10.1016/j.hrthm.2016.07.016. Epub 2016 Jul 17.

PMID:
27435587
20.

Consensus definitions of 14 severe acute toxic effects for childhood lymphoblastic leukaemia treatment: a Delphi consensus.

Schmiegelow K, Attarbaschi A, Barzilai S, Escherich G, Frandsen TL, Halsey C, Hough R, Jeha S, Kato M, Liang DC, Mikkelsen TS, Möricke A, Niinimäki R, Piette C, Putti MC, Raetz E, Silverman LB, Skinner R, Tuckuviene R, van der Sluis I, Zapotocka E; Ponte di Legno toxicity working group.

Lancet Oncol. 2016 Jun;17(6):e231-e239. doi: 10.1016/S1470-2045(16)30035-3. Review.

21.

Creation of an NCI comparative brain tumor consortium: informing the translation of new knowledge from canine to human brain tumor patients.

LeBlanc AK, Mazcko C, Brown DE, Koehler JW, Miller AD, Miller CR, Bentley RT, Packer RA, Breen M, Boudreau CE, Levine JM, Simpson RM, Halsey C, Kisseberth W, Rossmeisl JH Jr, Dickinson PJ, Fan TM, Corps K, Aldape K, Puduvalli V, Pluhar GE, Gilbert MR.

Neuro Oncol. 2016 Sep;18(9):1209-18. doi: 10.1093/neuonc/now051. Epub 2016 May 14. Review.

22.

Rate Versus Rhythm Control for Atrial Fibrillation.

Halsey C, Chugh A.

Heart Fail Clin. 2016 Apr;12(2):193-203. doi: 10.1016/j.hfc.2015.08.016. Review.

PMID:
26968665
23.

The ability to cross the blood-cerebrospinal fluid barrier is a generic property of acute lymphoblastic leukemia blasts.

Williams MT, Yousafzai YM, Elder A, Rehe K, Bomken S, Frishman-Levy L, Tavor S, Sinclair P, Dormon K, Masic D, Perry T, Weston VJ, Kearns P, Blair H, Russell LJ, Heidenreich O, Irving JA, Izraeli S, Vormoor J, Graham GJ, Halsey C.

Blood. 2016 Apr 21;127(16):1998-2006. doi: 10.1182/blood-2015-08-665034. Epub 2016 Feb 11.

24.

An atypical journey during a "typical" EP case.

Halsey C, Latchamsetty R.

HeartRhythm Case Rep. 2015 Nov 10;2(2):193-196. doi: 10.1016/j.hrcr.2015.10.008. eCollection 2016 Mar. No abstract available.

25.

Research into cancer metabolomics: Towards a clinical metamorphosis.

Olivares O, Däbritz JHM, King A, Gottlieb E, Halsey C.

Semin Cell Dev Biol. 2015 Jul;43:52-64. doi: 10.1016/j.semcdb.2015.09.008. Epub 2015 Sep 11. Review.

26.

Characterization of the metastatic phenotype of a panel of established osteosarcoma cells.

Ren L, Mendoza A, Zhu J, Briggs JW, Halsey C, Hong ES, Burkett SS, Morrow J, Lizardo MM, Osborne T, Li SQ, Luu HH, Meltzer P, Khanna C.

Oncotarget. 2015 Oct 6;6(30):29469-81. doi: 10.18632/oncotarget.5177.

27.

Conjugative Transfer in Staphylococcus aureus.

Halsey CR, Fey PD.

Methods Mol Biol. 2016;1373:83-7. doi: 10.1007/7651_2015_276.

PMID:
26194708
28.

Rate versus rhythm control for atrial fibrillation.

Halsey C, Chugh A.

Cardiol Clin. 2014 Nov;32(4):521-31. doi: 10.1016/j.ccl.2014.07.011. Epub 2014 Oct 23. Review.

PMID:
25443234
29.

Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition.

Irving J, Matheson E, Minto L, Blair H, Case M, Halsey C, Swidenbank I, Ponthan F, Kirschner-Schwabe R, Groeneveld-Krentz S, Hof J, Allan J, Harrison C, Vormoor J, von Stackelberg A, Eckert C.

Blood. 2014 Nov 27;124(23):3420-30. doi: 10.1182/blood-2014-04-531871. Epub 2014 Sep 24.

30.

Development of an in vitro model of acquired resistance to toceranib phosphate (Palladia®) in canine mast cell tumor.

Halsey CH, Gustafson DL, Rose BJ, Wolf-Ringwall A, Burnett RC, Duval DL, Avery AC, Thamm DH.

BMC Vet Res. 2014 May 6;10:105. doi: 10.1186/1746-6148-10-105.

31.

Pathologic and cardiovascular characterization of pheochromocytoma-associated cardiomyopathy in dogs.

Edmondson EF, Bright JM, Halsey CH, Ehrhart EJ.

Vet Pathol. 2015 Mar;52(2):338-43. doi: 10.1177/0300985814533805. Epub 2014 May 8.

PMID:
24810909
32.

Vitamin D and its effects on glucose homeostasis, cardiovascular function and immune function.

El-Fakhri N, McDevitt H, Shaikh MG, Halsey C, Ahmed SF.

Horm Res Paediatr. 2014;81(6):363-78. doi: 10.1159/000357731. Epub 2014 Apr 26. Review.

33.

Interleukin-15 enhances cellular proliferation and upregulates CNS homing molecules in pre-B acute lymphoblastic leukemia.

Williams MT, Yousafzai Y, Cox C, Blair A, Carmody R, Sai S, Chapman KE, McAndrew R, Thomas A, Spence A, Gibson B, Graham GJ, Halsey C.

Blood. 2014 May 15;123(20):3116-27. doi: 10.1182/blood-2013-05-499970. Epub 2014 Apr 3.

34.

Lymphangiosarcoma in 12 dogs: a case series (1998-2013).

Curran KM, Halsey CH, Worley DR.

Vet Comp Oncol. 2016 Jun;14(2):181-90. doi: 10.1111/vco.12087. Epub 2014 Feb 26.

PMID:
24612140
35.

The use of novel lymphatic endothelial cell-specific immunohistochemical markers to differentiate cutaneous angiosarcomas in dogs.

Halsey CH, Worley DR, Curran K, Charles JB, Ehrhart EJ.

Vet Comp Oncol. 2016 Sep;14(3):236-44. doi: 10.1111/vco.12088. Epub 2014 Mar 5.

PMID:
24593773
36.

Bilayer surface association of the pHLIP peptide promotes extensive backbone desolvation and helically-constrained structures.

Brown MC, Yakubu RA, Taylor J, Halsey CM, Xiong J, Jiji RD, Cooley JW.

Biophys Chem. 2014 Mar-Apr;187-188:1-6. doi: 10.1016/j.bpc.2013.12.004. Epub 2013 Dec 28.

PMID:
24440554
37.

Should children presenting with iron deficiency anaemia be screened for coeliac disease?

Winter S, Halsey C.

Arch Dis Child. 2014 Feb;99(2):180-2. doi: 10.1136/archdischild-2013-305591. Review. No abstract available.

PMID:
24420612
38.

Metalloproteins diversified: the auracyanins are a family of cupredoxins that stretch the spectral and redox limits of blue copper proteins.

King JD, McIntosh CL, Halsey CM, Lada BM, Niedzwiedzki DM, Cooley JW, Blankenship RE.

Biochemistry. 2013 Nov 19;52(46):8267-75. doi: 10.1021/bi401163g. Epub 2013 Nov 6.

PMID:
24147561
39.

GATA1-mutant clones are frequent and often unsuspected in babies with Down syndrome: identification of a population at risk of leukemia.

Roberts I, Alford K, Hall G, Juban G, Richmond H, Norton A, Vallance G, Perkins K, Marchi E, McGowan S, Roy A, Cowan G, Anthony M, Gupta A, Ho J, Uthaya S, Curley A, Rasiah SV, Watts T, Nicholl R, Bedford-Russell A, Blumberg R, Thomas A, Gibson B, Halsey C, Lee PW, Godambe S, Sweeney C, Bhatnagar N, Goriely A, Campbell P, Vyas P; Oxford-Imperial Down Syndrome Cohort Study Group.

Blood. 2013 Dec 5;122(24):3908-17. doi: 10.1182/blood-2013-07-515148. Epub 2013 Sep 10.

40.

Transcription factor Ets1 cooperates with estrogen receptor α to stimulate estradiol-dependent growth in breast cancer cells and tumors.

Kalet BT, Anglin SR, Handschy A, O'Donoghue LE, Halsey C, Chubb L, Korch C, Duval DL.

PLoS One. 2013 Jul 9;8(7):e68815. doi: 10.1371/journal.pone.0068815. Print 2013.

41.

Tumor P-Glycoprotein Correlates with Efficacy of PF-3758309 in in vitro and in vivo Models of Colorectal Cancer.

Bradshaw-Pierce EL, Pitts TM, Tan AC, McPhillips K, West M, Gustafson DL, Halsey C, Nguyen L, Lee NV, Kan JL, Murray BW, Eckhardt SG.

Front Pharmacol. 2013 Mar 22;4:22. doi: 10.3389/fphar.2013.00022. eCollection 2013.

42.
43.

Influence of the lipid environment on valinomycin structure and cation complex formation.

Halsey CM, Benham DA, JiJi RD, Cooley JW.

Spectrochim Acta A Mol Biomol Spectrosc. 2012 Oct;96:200-6. doi: 10.1016/j.saa.2012.05.022. Epub 2012 May 18.

PMID:
22683555
44.

What is your diagnosis? Intracranial mass in a dog.

Miller AG, Halsey CH, Miller MD, Bohn AA.

Vet Clin Pathol. 2011 Dec;40(4):563-564. doi: 10.1111/j.1939-165X.2011.00367.x. Epub 2011 Nov 3. No abstract available.

PMID:
22093113
45.
46.

Simultaneous observation of peptide backbone lipid solvation and α-helical structure by deep-UV resonance Raman spectroscopy.

Halsey CM, Xiong J, Oshokoya OO, Johnson JA, Shinde S, Beatty JT, Ghirlanda G, JiJi RD, Cooley JW.

Chembiochem. 2011 Sep 19;12(14):2125-8. doi: 10.1002/cbic.201100433. Epub 2011 Jul 27. No abstract available.

PMID:
21796753
47.

Deep-UV resonance Raman analysis of the Rhodobacter capsulatus cytochrome bc₁complex reveals a potential marker for the transmembrane peptide backbone.

Halsey CM, Oshokoya OO, Jiji RD, Cooley JW.

Biochemistry. 2011 Aug 2;50(30):6531-8. doi: 10.1021/bi200596w. Epub 2011 Jul 11.

PMID:
21718040
48.

Imaging diagnosis--magnetic resonance imaging findings of primary cerebral hemangioma.

Eichelberger BM, Kraft SL, Halsey CH, Park RD, Miller MD, Klopp L.

Vet Radiol Ultrasound. 2011 Mar-Apr;52(2):188-91. doi: 10.1111/j.1740-8261.2010.01766.x. Epub 2010 Dec 28.

PMID:
21388472
49.

The effect of ractopamine hydrochloride on gene expression in adipose tissues of finishing pigs.

Halsey CH, Weber PS, Reiter SS, Stronach BN, Bartosh JL, Bergen WG.

J Anim Sci. 2011 Apr;89(4):1011-9. doi: 10.2527/jas.2010-3269. Epub 2010 Dec 10.

PMID:
21148782
50.

Role of GATA-1s in early hematopoiesis and differences between alternative splicing in human and murine GATA-1.

Halsey C, Tunstall O, Gibson B, Roberts I, Graham G.

Blood. 2010 Apr 22;115(16):3415-6. doi: 10.1182/blood-2010-02-267930. No abstract available.

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