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Validation of the Seegene RV15 multiplex PCR for the detection of influenza A subtypes and influenza B lineages during national influenza surveillance in hospitalized adults.

LeBlanc JJ, ElSherif M, Mulpuru S, Warhuus M, Ambrose A, Andrew M, Boivin G, Bowie W, Chit A, Dos Santos G, Green K, Halperin SA, Hatchette TF, Ibarguchi B, Johnstone J, Katz K, Langley JM, Lagacé-Wiens P, Loeb M, Lund A, MacKinnon-Cameron D, McCarthy A, McElhaney JE, McGeer A, Poirier A, Powis J, Richardson D, Semret M, Shinde V, Smyth D, Trottier S, Valiquette L, Webster D, Ye L, McNeil SA.

J Med Microbiol. 2019 Jul 2. doi: 10.1099/jmm.0.001032. [Epub ahead of print]


Assessment of population immunity to measles in Ontario, Canada: a Canadian Immunization Research Network (CIRN) study.

Bolotin S, Severini A, Hatchette T, McLachlan E, Savage R, Hughes SL, Wang J, Deeks SL, Wilson S, Brisson M, Halperin SA, Gubbay J, Mazzulli T, Serhir B, Ward BJ, Crowcroft N.

Hum Vaccin Immunother. 2019 Jul 16:1-9. doi: 10.1080/21645515.2019.1619402. [Epub ahead of print]


Identification of Redox Partners of the Thiol-Disulfide Oxidoreductase SdbA in Streptococcus gordonii.

Jalal NA, Davey L, Halperin SA, Lee SF.

J Bacteriol. 2019 Apr 24;201(10). pii: e00030-19. doi: 10.1128/JB.00030-19. Print 2019 May 15.


Effectiveness of Influenza Vaccination on Hospitalizations and Risk Factors for Severe Outcomes in Hospitalized Patients With COPD.

Mulpuru S, Li L, Ye L, Hatchette T, Andrew MK, Ambrose A, Boivin G, Bowie W, Chit A, Dos Santos G, ElSherif M, Green K, Haguinet F, Halperin SA, Ibarguchi B, Johnstone J, Katz K, Langley JM, LeBlanc J, Loeb M, MacKinnon-Cameron D, McCarthy A, McElhaney JE, McGeer A, Powis J, Richardson D, Semret M, Shinde V, Smyth D, Trottier S, Valiquette L, Webster D, McNeil SA; Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN).

Chest. 2019 Jan;155(1):69-78. doi: 10.1016/j.chest.2018.10.044.


Burden of Children Hospitalized With Pertussis in Canada in the Acellular Pertussis Vaccine Era, 1999-2015.

Abu-Raya B, Bettinger JA, Vanderkooi OG, Vaudry W, Halperin SA, Sadarangani M; Members of the Canadian Immunization Monitoring Program, Active (IMPACT) .

J Pediatric Infect Dis Soc. 2018 Dec 8. doi: 10.1093/jpids/piy128. [Epub ahead of print]


Motivation for participating in phase 1 vaccine trials: Comparison of an influenza and an Ebola randomized controlled trial.

Cattapan A, Browne K, Halperin DM, Di Castri A, Fullsack P, Graham J, Langley JM, Taylor BA, McNeil SA, Halperin SA.

Vaccine. 2019 Jan 7;37(2):289-295. doi: 10.1016/j.vaccine.2018.11.014. Epub 2018 Dec 7.


Effect of alcohol skin cleansing on vaccination-associated infections and local skin reactions: a randomized controlled trial.

Wong H, Moss C, Moss SM, Shah V, Halperin SA, Ito S, Mithal P, Qu A, Taddio A.

Hum Vaccin Immunother. 2019;15(4):995-1002. doi: 10.1080/21645515.2018.1553474. Epub 2019 Jan 16.


Vaccination Against Influenza in Pregnancy: A Survey of Canadian Maternity Care Providers.

Dubé E, Gagnon D, Kaminsky K, Green CR, Ouakki M, Bettinger JA, Brousseau N, Castillo E, Crowcroft NS, Driedger SM, Greyson D, Fell D, Fisher W, Gagneur A, Guay M, Halperin D, Halperin SA, MacDonald S, Meyer SB, Waite NM, Wilson K, Witteman HO, Yudin M, Cook JL; Canadian Immunization Network.

J Obstet Gynaecol Can. 2019 Apr;41(4):479-488. doi: 10.1016/j.jogc.2018.09.007. Epub 2018 Nov 6.


Knowledge, attitudes, behaviours, and beliefs of healthcare provider students regarding mandatory influenza vaccination.

Ghandora H, Halperin DM, Isenor JE, Taylor BA, Fullsack P, Di Castri AM, Halperin SA.

Hum Vaccin Immunother. 2019;15(3):700-709. doi: 10.1080/21645515.2018.1543523. Epub 2019 Jan 4.


Clinical Relevance of Petit's Triangle: A Forgotten Landmark.

Halperin S, Julian S, Penn D, Zisholtz B.

Rev Urol. 2018;20(2):112-114. doi: 10.3909/riu0796.


CRISPR-guided DNA polymerases enable diversification of all nucleotides in a tunable window.

Halperin SO, Tou CJ, Wong EB, Modavi C, Schaffer DV, Dueber JE.

Nature. 2018 Aug;560(7717):248-252. doi: 10.1038/s41586-018-0384-8. Epub 2018 Aug 1.


A Randomized Controlled Trial of the Safety and Immunogenicity of Tetanus, Diphtheria, and Acellular Pertussis Vaccine Immunization During Pregnancy and Subsequent Infant Immune Response.

Halperin SA, Langley JM, Ye L, MacKinnon-Cameron D, Elsherif M, Allen VM, Smith B, Halperin BA, McNeil SA, Vanderkooi OG, Dwinnell S, Wilson RD, Tapiero B, Boucher M, Le Saux N, Gruslin A, Vaudry W, Chandra S, Dobson S, Money D.

Clin Infect Dis. 2018 Sep 14;67(7):1063-1071. doi: 10.1093/cid/ciy244.


mRNA-seq whole transcriptome profiling of fresh frozen versus archived fixed tissues.

Bossel Ben-Moshe N, Gilad S, Perry G, Benjamin S, Balint-Lahat N, Pavlovsky A, Halperin S, Markus B, Yosepovich A, Barshack I, Gal-Yam EN, Domany E, Kaufman B, Dadiani M.

BMC Genomics. 2018 May 30;19(1):419. doi: 10.1186/s12864-018-4761-3.


Contact among healthcare workers in the hospital setting: developing the evidence base for innovative approaches to infection control.

English KM, Langley JM, McGeer A, Hupert N, Tellier R, Henry B, Halperin SA, Johnston L, Pourbohloul B.

BMC Infect Dis. 2018 Apr 17;18(1):184. doi: 10.1186/s12879-018-3093-x.


A Respiratory Syncytial Virus Vaccine Based on the Small Hydrophobic Protein Ectodomain Presented With a Novel Lipid-Based Formulation Is Highly Immunogenic and Safe in Adults: A First-in-Humans Study.

Langley JM, MacDonald LD, Weir GM, MacKinnon-Cameron D, Ye L, McNeil S, Schepens B, Saelens X, Stanford MM, Halperin SA.

J Infect Dis. 2018 Jul 2;218(3):378-387. doi: 10.1093/infdis/jiy177.


Influenza vaccine effectiveness to prevent influenza-related hospitalizations and serious outcomes in Canadian adults over the 2011/12 through 2013/14 influenza seasons: A pooled analysis from the Canadian Immunization Research Network (CIRN) Serious Outcomes Surveillance (SOS Network).

Nichols MK, Andrew MK, Hatchette TF, Ambrose A, Boivin G, Bowie W, Chit A, Dos Santos G, ElSherif M, Green K, Haguinet F, Halperin SA, Ibarguchi B, Johnstone J, Katz K, Lagacé-Wiens P, Langley JM, LeBlanc J, Loeb M, MacKinnon-Cameron D, McCarthy A, McElhaney JE, McGeer A, Poirier A, Powis J, Richardson D, Schuind A, Semret M, Shinde V, Smith S, Smyth D, Stiver G, Taylor G, Trottier S, Valiquette L, Webster D, Ye L, McNeil SA; Serious Outcomes Surveillance Network of the Canadian Immunization Research Network (CIRN), the Toronto Invasive Bacterial Diseases Network (TIBDN).

Vaccine. 2018 Apr 12;36(16):2166-2175. doi: 10.1016/j.vaccine.2018.02.093. Epub 2018 Mar 13.


Immunogenicity and safety of one or two doses of the quadrivalent meningococcal vaccine MenACWY-TT given alone or with the 13-valent pneumococcal conjugate vaccine in toddlers: A phase III, open-label, randomised study.

Cutland CL, Nolan T, Halperin SA, Kurugol Z, Ahmed K, Perrett KP, Richmond P, Marshall HS, Ceyhan M, Kolhe D, Hezareh M, Van Der Wielen M.

Vaccine. 2018 Mar 27;36(14):1908-1916. doi: 10.1016/j.vaccine.2018.02.013. Epub 2018 Mar 2.


Randomized Controlled Trial of the Safety and Immunogenicity of Revaccination With Tetanus-Diphtheria-Acellular Pertussis Vaccine (Tdap) in Adults 10 Years After a Previous Dose.

Halperin SA, Donovan C, Marshall GS, Pool V, Decker MD, Johnson DR, Greenberg DP; Tdap Booster Investigators.

J Pediatric Infect Dis Soc. 2019 May 11;8(2):105-114. doi: 10.1093/jpids/pix113.


Waning of measles maternal antibody in infants in measles elimination settings - A systematic literature review.

Guerra FM, Crowcroft NS, Friedman L, Deeks SL, Halperin SA, Severini A, Hatchette TF, Bolotin S; Immunity of Canadians and Risk of Epidemics (iCARE) Network.

Vaccine. 2018 Feb 28;36(10):1248-1255. doi: 10.1016/j.vaccine.2018.01.002. Epub 2018 Feb 2. Review.


Recapitulating the clinical scenario of BRCA-associated pancreatic cancer in pre-clinical models.

Golan T, Stossel C, Atias D, Buzhor E, Halperin S, Cohen K, Raitses-Gurevich M, Glick Y, Raskin S, Yehuda D, Feldman A, Schvimer M, Friedman E, Karni R, Wilson JM, Denroche RE, Lungu I, Bartlett JMS, Mbabaali F, Gallinger S, Berger R.

Int J Cancer. 2018 Jul 1;143(1):179-183. doi: 10.1002/ijc.31292. Epub 2018 Feb 23.


Functional activity of maternal and cord antibodies elicited by an investigational group B Streptococcus trivalent glycoconjugate vaccine in pregnant women.

Fabbrini M, Rigat F, Tuscano G, Chiarot E, Donders G, Devlieger R, Filippini S, Frigimelica E, Forte P, Wittke F, Halperin SA, Slobod K, Grandi G, Margarit I.

J Infect. 2018 May;76(5):449-456. doi: 10.1016/j.jinf.2018.01.006. Epub 2018 Jan 31.


Prolonged Recurrent Abdominal Pain is Associated With Ongoing Underlying Mucosal Inflammation in Patients who had an Episode of Acute Complicated Diverticulitis.

Lahat A, Necula D, Yavzori M, Picard O, Halperin S, Eliakim R, Ben-Horin S.

J Clin Gastroenterol. 2019 May/Jun;53(5):e178-e185. doi: 10.1097/MCG.0000000000000980.


Influenza vaccine effectiveness against influenza-related hospitalization during a season with mixed outbreaks of four influenza viruses: a test-negative case-control study in adults in Canada.

Andrew MK, Shinde V, Hatchette T, Ambrose A, Boivin G, Bowie W, Chit A, Dos Santos G, ElSherif M, Green K, Haguinet F, Halperin SA, Ibarguchi B, Johnstone J, Katz K, Langley JM, LeBlanc J, Loeb M, MacKinnon-Cameron D, McCarthy A, McElhaney J, McGeer A, Nichols MK, Powis J, Richardson D, Semret M, Stiver G, Trottier S, Valiquette L, Webster D, Ye L, McNeil SA; Public Health Agency of Canada/Canadian Institutes of Health Research Influenza Research Network (PCIRN) Serious Outcomes Surveillance Network and the Toronto Invasive Bacterial Diseases Network (TIBDN).

BMC Infect Dis. 2017 Dec 29;17(1):805. doi: 10.1186/s12879-017-2905-8.


Case-control study of household contacts to examine immunological protection from Bordetella pertussis transmission - study protocol.

Bolotin S, Johnson C, Quach S, Ambrose A, DeCoutere S, Deeks SL, Drews S, Faheem A, Green K, Halperin SA, Hoang L, Jamieson F, Kollmann T, Marchand-Austin A, McCormack D, McGeer A, Murti M, Bba AO, Rebbapragada A, Vanderkooi OG, Wang J, Warshawsky B, Crowcroft NS; Canadian Immunization Research Network Provincial Collaborative Network.

CMAJ Open. 2017 Dec 19;5(4):E872-E877. doi: 10.9778/cmajo.20170072.


Invasive Haemophilus Influenzae Type B Infections in Children with Cancer in the Era of Infant HIB Immunization Programs (1991-2014): A Report From the Canadian Immunization Monitoring Program Active.

McNair J, Smith A, Bettinger JA, Vaudry W, Tan B, Desai S, Halperin SA, Top KA; Canadian Immunization Monitoring Program Active (IMPACT) Investigators.

Pediatr Infect Dis J. 2018 Jul;37(7):726-728. doi: 10.1097/INF.0000000000001850.


Expression, purification, and functional analysis of an antigen-targeting fusion protein composed of CD40 ligand and the C-terminal fragment of ovalbumin.

Shi Y, Halperin SA, Lee SF.

Protein Expr Purif. 2018 Feb;142:37-44. doi: 10.1016/j.pep.2017.09.015. Epub 2017 Sep 30.


Type III hypersensitivity reactions to a B cell epitope antigen are abrogated using a depot forming vaccine platform.

MacDonald LD, MacKay A, Kaliaperumal V, Weir G, Penwell A, Rajagopalan R, Langley JM, Halperin S, Mansour M, Stanford MM.

Hum Vaccin Immunother. 2018 Jan 2;14(1):59-66. doi: 10.1080/21645515.2017.1375637. Epub 2017 Oct 30.


The Importance of Frailty in the Assessment of Influenza Vaccine Effectiveness Against Influenza-Related Hospitalization in Elderly People.

Andrew MK, Shinde V, Ye L, Hatchette T, Haguinet F, Dos Santos G, McElhaney JE, Ambrose A, Boivin G, Bowie W, Chit A, ElSherif M, Green K, Halperin S, Ibarguchi B, Johnstone J, Katz K, Langley J, Leblanc J, Loeb M, MacKinnon-Cameron D, McCarthy A, McGeer A, Powis J, Richardson D, Semret M, Stiver G, Trottier S, Valiquette L, Webster D, McNeil SA; Serious Outcomes Surveillance Network of the Public Health Agency of Canada/Canadian Institutes of Health Research Influenza Research Network (PCIRN) and the Toronto Invasive Bacterial Diseases Network (TIBDN).

J Infect Dis. 2017 Aug 15;216(4):405-414. doi: 10.1093/infdis/jix282.


Placement Instability Among Young People Removed from Their Original Family and the Likely Mental Health Implications.

Rice S, Cotton S, Moeller-Saxone K, Mihalopoulos C, Magnus A, Harvey C, Humphreys C, Halperin S, Scheppokat A, McGorry P, Herrman H.

Shanghai Arch Psychiatry. 2017 Apr 25;29(2):85-94. doi: 10.11919/j.issn.1002-0829.216090.


Toll-like receptor 3 blockade in rhinovirus-induced experimental asthma exacerbations: A randomized controlled study.

Silkoff PE, Flavin S, Gordon R, Loza MJ, Sterk PJ, Lutter R, Diamant Z, Turner RB, Lipworth BJ, Proud D, Singh D, Eich A, Backer V, Gern JE, Herzmann C, Halperin SA, Mensinga TT, Del Vecchio AM, Branigan P, San Mateo L, Baribaud F, Barnathan ES, Johnston SL.

J Allergy Clin Immunol. 2018 Apr;141(4):1220-1230. doi: 10.1016/j.jaci.2017.06.027. Epub 2017 Jul 20.


Cellular immune responses of older adults to four influenza vaccines: Results of a randomized, controlled comparison.

Kumar A, McElhaney JE, Walrond L, Cyr TD, Merani S, Kollmann TR, Halperin SA, Scheifele DW.

Hum Vaccin Immunother. 2017 Sep 2;13(9):2048-2057. doi: 10.1080/21645515.2017.1337615. Epub 2017 Jun 21.


Assessing the safety and immunogenicity of recombinant vesicular stomatitis virus Ebola vaccine in healthy adults: a randomized clinical trial.

ElSherif MS, Brown C, MacKinnon-Cameron D, Li L, Racine T, Alimonti J, Rudge TL, Sabourin C, Silvera P, Hooper JW, Kwilas SA, Kilgore N, Badorrek C, Ramsey WJ, Heppner DG, Kemp T, Monath TP, Nowak T, McNeil SA, Langley JM, Halperin SA; Canadian Immunization Research Network.

CMAJ. 2017 Jun 19;189(24):E819-E827. doi: 10.1503/cmaj.170074.


Six-Month Safety Data of Recombinant Vesicular Stomatitis Virus-Zaire Ebola Virus Envelope Glycoprotein Vaccine in a Phase 3 Double-Blind, Placebo-Controlled Randomized Study in Healthy Adults.

Halperin SA, Arribas JR, Rupp R, Andrews CP, Chu L, Das R, Simon JK, Onorato MT, Liu K, Martin J, Helmond FA; V920-012 Study Team.

J Infect Dis. 2017 Jun 15;215(12):1789-1798. doi: 10.1093/infdis/jix189.


Pancreatic cancer ascites xenograft-an expeditious model mirroring advanced therapeutic resistant disease.

Golan T, Stossel C, Schvimer M, Atias D, Halperin S, Buzhor E, Raitses-Gurevich M, Cohen K, Pri-Chen S, Wilson J, Denroche RE, Lungu I, Bartlett JMS, Mbabaali F, Yarden Y, Nataraj NB, Gallinger S, Berger R.

Oncotarget. 2017 Jun 20;8(25):40778-40790. doi: 10.18632/oncotarget.17253.


Maternal immunisation: collaborating with mother nature.

Marchant A, Sadarangani M, Garand M, Dauby N, Verhasselt V, Pereira L, Bjornson G, Jones CE, Halperin SA, Edwards KM, Heath P, Openshaw PJ, Scheifele DW, Kollmann TR.

Lancet Infect Dis. 2017 Jul;17(7):e197-e208. doi: 10.1016/S1473-3099(17)30229-3. Epub 2017 Apr 19. Review.


Pertussis and influenza immunisation during pregnancy: a landscape review.

Abu Raya B, Edwards KM, Scheifele DW, Halperin SA.

Lancet Infect Dis. 2017 Jul;17(7):e209-e222. doi: 10.1016/S1473-3099(17)30190-1. Epub 2017 Apr 19. Review.


Knowledge, attitudes, beliefs, and behaviors of university students, faculty, and staff during a meningococcal serogroup B outbreak vaccination program.

MacDougall DM, Langley JM, Li L, Ye L, MacKinnon-Cameron D, Top KA, McNeil SA, Halperin BA, Swain A, Bettinger JA, Dubé E, De Serres G, Halperin SA; Canadian Immunization Research Network.

Vaccine. 2017 Apr 25;35(18):2520-2530. doi: 10.1016/j.vaccine.2017.02.011. Epub 2017 Mar 24.


Novel Surgical Approach for Fixation of a Posterior Chamber Intraocular Lens Using Gore-Tex Suture.

Mantopoulos D, Vloka CN, Halperin SJ, Green SN, Prenner JL.

Retina. 2017 Dec;37(12):2362-2364. doi: 10.1097/IAE.0000000000001595. No abstract available.


The Youth Mood Clinic: an innovative service for the treatment of severe and complex depression.

Rice SM, Halperin S, Cahill S, Cranston I, Phelan M, Hetrick SE, Blaikie S, Edwards J, Koutsogiannis J, Davey CG.

Australas Psychiatry. 2017 Apr;25(2):112-116. doi: 10.1177/1039856216689002. Epub 2017 Jan 31.


A controlled trial of implementing a complex mental health intervention for carers of vulnerable young people living in out-of-home care: the ripple project.

Herrman H, Humphreys C, Halperin S, Monson K, Harvey C, Mihalopoulos C, Cotton S, Mitchell P, Glynn T, Magnus A, Murray L, Szwarc J, Davis E, Havighurst S, McGorry P, Tyano S, Kaplan I, Rice S, Moeller-Saxone K.

BMC Psychiatry. 2016 Dec 7;16(1):436.


Mutation of the Streptococcus gordonii Thiol-Disulfide Oxidoreductase SdbA Leads to Enhanced Biofilm Formation Mediated by the CiaRH Two-Component Signaling System.

Davey L, Halperin SA, Lee SF.

PLoS One. 2016 Nov 15;11(11):e0166656. doi: 10.1371/journal.pone.0166656. eCollection 2016.


Assessing the risk of intussusception and rotavirus vaccine safety in Canada.

Hawken S, Ducharme R, Rosella LC, Benchimol EI, Langley JM, Wilson K, Crowcroft NS, Halperin SA, Desai S, Naus M, Sanford CJ, Mahmud SM, Deeks SL.

Hum Vaccin Immunother. 2017 Mar 4;13(3):703-710. doi: 10.1080/21645515.2016.1240846. Epub 2016 Nov 11.


Pertussis: Biology, epidemiology and prevention.

Saadatian-Elahi M, Plotkin S, Mills KHG, Halperin SA, McIntyre PB, Picot V, Louis J, Johnson DR.

Vaccine. 2016 Nov 21;34(48):5819-5826. doi: 10.1016/j.vaccine.2016.10.029. Epub 2016 Oct 22.


The role of healthcare provider attitudes in increasing willingness to accept seasonal influenza vaccine policy changes.

Slaunwhite JM, Smith SM, Halperin BA, Langley JM, Halperin SA.

Vaccine. 2016 Nov 11;34(47):5704-5707. doi: 10.1016/j.vaccine.2016.08.083. Epub 2016 Sep 21.


Thiol-Disulfide Exchange in Gram-Positive Firmicutes.

Davey L, Halperin SA, Lee SF.

Trends Microbiol. 2016 Nov;24(11):902-915. doi: 10.1016/j.tim.2016.06.010. Epub 2016 Jul 15. Review.


Do Dose Numbers Matter?: Evaluation of Differing Infant and Toddler Meningococcal C Conjugate Vaccine Programs in Canadian Children.

Bettinger JA, Vanderkooi OG, Scheifele DW, Halperin SA, Kellner JD, Schryvers A, De Serres G, Alcantara J.

Pediatr Infect Dis J. 2016 Nov;35(11):1242-1246.


Integrating family work into the treatment of young people with severe and complex depression: a developmentally focused model.

Rice S, Halperin S, Blaikie S, Monson K, Stefaniak R, Phelan M, Davey C.

Early Interv Psychiatry. 2018 Apr;12(2):258-266. doi: 10.1111/eip.12383. Epub 2016 Oct 2.


Meeting the primary care needs 
of young people in residential care.

Moeller-Saxone K, McCutcheon L, Halperin S, Herrman H, Chanen AM.

Aust Fam Physician. 2016 Oct;45(10):706-711.


A Randomized, Controlled, Observer-Blinded Phase 1 Study of the Safety and Immunogenicity of a Respiratory Syncytial Virus Vaccine With or Without Alum Adjuvant.

Langley JM, Aggarwal N, Toma A, Halperin SA, McNeil SA, Fissette L, Dewé W, Leyssen M, Toussaint JF, Dieussaert I.

J Infect Dis. 2017 Jan 1;215(1):24-33. doi: 10.1093/infdis/jiw453. Epub 2016 Sep 29.


Immunizing Patients With Adverse Events After Immunization and Potential Contraindications to Immunization: A Report From the Special Immunization Clinics Network.

Top KA, Billard MN, Gariepy MC, Rouleau I, Pernica JM, Pham-Huy A, Quach C, Tran D, Vaudry W, Dobson S, Boucher FD, Carignan A, Jadavji T, McConnell A, McNeil SA, Halperin SA, De Serres G; Canadian Immunization Research Network’s (CIRN) Special Immunization Clinics Network investigators.

Pediatr Infect Dis J. 2016 Dec;35(12):e384-e391.


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