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Items: 12

1.

Codon-Optimization of Wild-Type Adeno-Associated Virus Capsid Sequences Enhances DNA Family Shuffling while Conserving Functionality.

Cabanes-Creus M, Ginn SL, Amaya AK, Liao SHY, Westhaus A, Hallwirth CV, Wilmott P, Ward J, Dilworth KL, Santilli G, Rybicki A, Nakai H, Thrasher AJ, Filip AC, Alexander IE, Lisowski L.

Mol Ther Methods Clin Dev. 2018 Nov 1;12:71-84. doi: 10.1016/j.omtm.2018.10.016. eCollection 2019 Mar 15.

2.

Identification of liver-specific enhancer-promoter activity in the 3' untranslated region of the wild-type AAV2 genome.

Logan GJ, Dane AP, Hallwirth CV, Smyth CM, Wilkie EE, Amaya AK, Zhu E, Khandekar N, Ginn SL, Liao SHY, Cunningham SC, Sasaki N, Cabanes-Creus M, Tam PPL, Russell DW, Lisowski L, Alexander IE.

Nat Genet. 2017 Aug;49(8):1267-1273. doi: 10.1038/ng.3893. Epub 2017 Jun 19.

PMID:
28628105
3.

Ub-ISAP: a streamlined UNIX pipeline for mining unique viral vector integration sites from next generation sequencing data.

Kamboj A, Hallwirth CV, Alexander IE, McCowage GB, Kramer B.

BMC Bioinformatics. 2017 Jun 17;18(1):305. doi: 10.1186/s12859-017-1719-4.

4.

Limiting Thymic Precursor Supply Increases the Risk of Lymphoid Malignancy in Murine X-Linked Severe Combined Immunodeficiency.

Ginn SL, Hallwirth CV, Liao SH, Teber ET, Arthur JW, Wu J, Lee HC, Tay SS, Hu M, Reddel RR, McCormack MP, Thrasher AJ, Cavazzana M, Alexander SI, Alexander IE.

Mol Ther Nucleic Acids. 2017 Mar 17;6:1-14. doi: 10.1016/j.omtn.2016.11.011. Epub 2016 Dec 10.

5.

Germline viral "fossils" guide in silico reconstruction of a mid-Cenozoic era marsupial adeno-associated virus.

Smith RH, Hallwirth CV, Westerman M, Hetherington NA, Tseng YS, Cecchini S, Virag T, Ziegler ML, Rogozin IB, Koonin EV, Agbandje-McKenna M, Kotin RM, Alexander IE.

Sci Rep. 2016 Jul 5;6:28965. doi: 10.1038/srep28965.

6.

Coherence analysis discriminates between retroviral integration patterns in CD34(+) cells transduced under differing clinical trial conditions.

Hallwirth CV, Garg G, Peters TJ, Kramer BA, Malani NV, Hyman J, Ruan X, Ginn SL, Hetherington NA, Veeravalli L, Shahab A, Ranganathan S, Wei CL, Liddle C, Thrasher AJ, Bushman FD, Buckley MJ, Alexander IE.

Mol Ther Methods Clin Dev. 2015 Apr 29;2:15015. doi: 10.1038/mtm.2015.15. eCollection 2015.

7.

Modeling correction of severe urea cycle defects in the growing murine liver using a hybrid recombinant adeno-associated virus/piggyBac transposase gene delivery system.

Cunningham SC, Siew SM, Hallwirth CV, Bolitho C, Sasaki N, Garg G, Michael IP, Hetherington NA, Carpenter K, de Alencastro G, Nagy A, Alexander IE.

Hepatology. 2015 Aug;62(2):417-28. doi: 10.1002/hep.27842. Epub 2015 May 23.

PMID:
26011400
8.

Probing the closed-loop model of mRNA translation in living cells.

Archer SK, Shirokikh NE, Hallwirth CV, Beilharz TH, Preiss T.

RNA Biol. 2015;12(3):248-54. doi: 10.1080/15476286.2015.1017242.

9.

Impact of next-generation sequencing error on analysis of barcoded plasmid libraries of known complexity and sequence.

Deakin CT, Deakin JJ, Ginn SL, Young P, Humphreys D, Suter CM, Alexander IE, Hallwirth CV.

Nucleic Acids Res. 2014;42(16):e129. doi: 10.1093/nar/gku607. Epub 2014 Jul 10.

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