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Items: 9

1.

The endogenous galactofuranosidase GlfH1 hydrolyzes mycobacterial arabinogalactan.

Shen L, Viljoen A, Villaume S, Joe M, Halloum I, Chêne LP, Méry A, Fabre E, Takegawa K, Lowary TL, Vincent SP, Kremer L, Guérardel Y, Mariller C.

J Biol Chem. 2020 Feb 27. pii: jbc.RA119.011817. doi: 10.1074/jbc.RA119.011817. [Epub ahead of print]

2.

Antitumor activity of the synthetic retinoid ST1926 on primary effusion lymphoma in vitro and in vivo models.

Karam L, Houshaymi B, Abdel-Samad R, Jaafar M, Halloum I, Pisano C, Neipel F, Darwiche N, Abou Merhi R.

Oncol Rep. 2018 Feb;39(2):721-730. doi: 10.3892/or.2017.6137. Epub 2017 Dec 5.

PMID:
29207182
3.

Identification of inhibitors targeting Mycobacterium tuberculosis cell wall biosynthesis via dynamic combinatorial chemistry.

Fu J, Fu H, Dieu M, Halloum I, Kremer L, Xia Y, Pan W, Vincent SP.

Chem Commun (Camb). 2017 Sep 26;53(77):10632-10635. doi: 10.1039/c7cc05251k.

PMID:
28905050
4.

Dry-Powder Inhaler Formulation of Rifampicin: An Improved Targeted Delivery System for Alveolar Tuberculosis.

Rawal T, Kremer L, Halloum I, Butani S.

J Aerosol Med Pulm Drug Deliv. 2017 Dec;30(6):388-398. doi: 10.1089/jamp.2017.1379. Epub 2017 May 16.

PMID:
28510480
5.

Resistance to Thiacetazone Derivatives Active against Mycobacterium abscessus Involves Mutations in the MmpL5 Transcriptional Repressor MAB_4384.

Halloum I, Viljoen A, Khanna V, Craig D, Bouchier C, Brosch R, Coxon G, Kremer L.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02509-16. doi: 10.1128/AAC.02509-16. Print 2017 Apr.

6.

Mycobacterium abscessus-Induced Granuloma Formation Is Strictly Dependent on TNF Signaling and Neutrophil Trafficking.

Bernut A, Nguyen-Chi M, Halloum I, Herrmann JL, Lutfalla G, Kremer L.

PLoS Pathog. 2016 Nov 2;12(11):e1005986. doi: 10.1371/journal.ppat.1005986. eCollection 2016 Nov.

7.

Attenuation of Mycobacterium species through direct and macrophage mediated pathway by unsymmetrical diaryl urea.

Velappan AB, Charan Raja MR, Datta D, Tsai YT, Halloum I, Wan B, Kremer L, Gramajo H, Franzblau SG, Kar Mahapatra S, Debnath J.

Eur J Med Chem. 2017 Jan 5;125:825-841. doi: 10.1016/j.ejmech.2016.09.083. Epub 2016 Sep 26.

PMID:
27750200
8.

Deletion of a dehydratase important for intracellular growth and cording renders rough Mycobacterium abscessus avirulent.

Halloum I, Carrère-Kremer S, Blaise M, Viljoen A, Bernut A, Le Moigne V, Vilchèze C, Guérardel Y, Lutfalla G, Herrmann JL, Jacobs WR Jr, Kremer L.

Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):E4228-37. doi: 10.1073/pnas.1605477113. Epub 2016 Jul 6.

9.

A new dehydratase conferring innate resistance to thiacetazone and intra-amoebal survival of Mycobacterium smegmatis.

Carrère-Kremer S, Blaise M, Singh VK, Alibaud L, Tuaillon E, Halloum I, van de Weerd R, Guérardel Y, Drancourt M, Takiff H, Geurtsen J, Kremer L.

Mol Microbiol. 2015 Jun;96(5):1085-102. doi: 10.1111/mmi.12992. Epub 2015 Mar 28.

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