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Items: 1 to 50 of 599

1.
2.

Clonal expansion of mitochondrial DNA deletions is a private mechanism of aging in long-lived animals.

Lakshmanan LN, Yee Z, Ng LF, Gunawan R, Halliwell B, Gruber J.

Aging Cell. 2018 Oct;17(5):e12814. doi: 10.1111/acel.12814. Epub 2018 Jul 24.

3.

A novel vibration-induced exercise paradigm improves fitness and lipid metabolism of Caenorhabditis elegans.

Teo E, Batchu KC, Barardo D, Xiao L, Cazenave-Gassiot A, Tolwinski N, Wenk M, Halliwell B, Gruber J.

Sci Rep. 2018 Jun 20;8(1):9420. doi: 10.1038/s41598-018-27330-3.

4.

The proteobacterial species Burkholderia pseudomallei produces ergothioneine, which enhances virulence in mammalian infection.

Gamage AM, Liao C, Cheah IK, Chen Y, Lim DRX, Ku JWK, Chee RSL, Gengenbacher M, Seebeck FP, Halliwell B, Gan YH.

FASEB J. 2018 Jun 11:fj201800716. doi: 10.1096/fj.201800716. [Epub ahead of print]

PMID:
29890088
5.

Ergothioneine - a diet-derived antioxidant with therapeutic potential.

Halliwell B, Cheah IK, Tang RMY.

FEBS Lett. 2018 May 31. doi: 10.1002/1873-3468.13123. [Epub ahead of print] Review.

PMID:
29851075
6.

Mini-Review: Oxidative stress, redox stress or redox success?

Gutteridge JMC, Halliwell B.

Biochem Biophys Res Commun. 2018 Jul 12;502(2):183-186. doi: 10.1016/j.bbrc.2018.05.045. Epub 2018 May 24.

PMID:
29752940
7.

Maternal effects impact decision-making in a viviparous lizard.

Munch KL, Noble DWA, Botterill-James T, Koolhof IS, Halliwell B, Wapstra E, While GM.

Biol Lett. 2018 Apr;14(4). pii: 20170556. doi: 10.1098/rsbl.2017.0556.

PMID:
29643218
8.

Reactive Oxygen Species: Radical Factors in the Evolution of Animal Life: A molecular timescale from Earth's earliest history to the rise of complex life.

Taverne YJ, Merkus D, Bogers AJ, Halliwell B, Duncker DJ, Lyons TW.

Bioessays. 2018 Mar;40(3). doi: 10.1002/bies.201700158. Epub 2018 Feb 7. Review.

PMID:
29411901
9.

Distribution and accumulation of dietary ergothioneine and its metabolites in mouse tissues.

Tang RMY, Cheah IK, Yew TSK, Halliwell B.

Sci Rep. 2018 Jan 25;8(1):1601. doi: 10.1038/s41598-018-20021-z.

10.

Live bearing promotes the evolution of sociality in reptiles.

Halliwell B, Uller T, Holland BR, While GM.

Nat Commun. 2017 Dec 11;8(1):2030. doi: 10.1038/s41467-017-02220-w.

11.

Approaches for extending human healthspan: from antioxidants to healthspan pharmacology.

Gruber J, Halliwell B.

Essays Biochem. 2017 Jul 11;61(3):389-399. doi: 10.1042/EBC20160091. Print 2017 Jul 15. Review.

PMID:
28698312
12.

Family aggression in a social lizard.

Botterill-James T, Halliwell B, McKeown S, Sillince J, Uller T, Wapstra E, While GM.

Sci Rep. 2017 Jun 14;7(1):3502. doi: 10.1038/s41598-017-03531-0.

13.

Identification of a previously undetected metabolic defect in the Complex II Caenorhabditis elegans mev-1 mutant strain using respiratory control analysis.

Fong S, Ng LF, Ng LT, Moore PK, Halliwell B, Gruber J.

Biogerontology. 2017 Apr;18(2):189-200. doi: 10.1007/s10522-016-9672-6. Epub 2016 Dec 30.

PMID:
28039571
14.

Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model.

Fong S, Teo E, Ng LF, Chen CB, Lakshmanan LN, Tsoi SY, Moore PK, Inoue T, Halliwell B, Gruber J.

Sci Rep. 2016 Sep 22;6:33781. doi: 10.1038/srep33781.

15.

Administration of Pure Ergothioneine to Healthy Human Subjects: Uptake, Metabolism, and Effects on Biomarkers of Oxidative Damage and Inflammation.

Cheah IK, Tang RM, Yew TS, Lim KH, Halliwell B.

Antioxid Redox Signal. 2017 Feb 10;26(5):193-206. doi: 10.1089/ars.2016.6778. Epub 2016 Sep 7.

PMID:
27488221
16.

Ergothioneine levels in an elderly population decrease with age and incidence of cognitive decline; a risk factor for neurodegeneration?

Cheah IK, Feng L, Tang RMY, Lim KHC, Halliwell B.

Biochem Biophys Res Commun. 2016 Sep 9;478(1):162-167. doi: 10.1016/j.bbrc.2016.07.074. Epub 2016 Jul 19.

PMID:
27444382
17.

Ergothioneine, an adaptive antioxidant for the protection of injured tissues? A hypothesis.

Halliwell B, Cheah IK, Drum CL.

Biochem Biophys Res Commun. 2016 Feb 5;470(2):245-250. doi: 10.1016/j.bbrc.2015.12.124. Epub 2016 Jan 6. Review.

PMID:
26772879
18.

Liver ergothioneine accumulation in a guinea pig model of non-alcoholic fatty liver disease. A possible mechanism of defence?

Cheah IK, Tang R, Ye P, Yew TS, Lim KH, Halliwell B.

Free Radic Res. 2016;50(1):14-25. doi: 10.3109/10715762.2015.1099642. Epub 2015 Dec 4.

PMID:
26634964
19.

Context-Dependent Role of Mitochondrial Fusion-Fission in Clonal Expansion of mtDNA Mutations.

Tam ZY, Gruber J, Halliwell B, Gunawan R.

PLoS Comput Biol. 2015 May 21;11(5):e1004183. doi: 10.1371/journal.pcbi.1004183. eCollection 2015 May.

20.

Are mutagenic non D-loop direct repeat motifs in mitochondrial DNA under a negative selection pressure?

Lakshmanan LN, Gruber J, Halliwell B, Gunawan R.

Nucleic Acids Res. 2015 Apr 30;43(8):4098-108. doi: 10.1093/nar/gkv299. Epub 2015 Apr 8.

21.

Metabolic signatures of renal cell carcinoma.

Lim HY, Yip YM, Chiong E, Tiong HY, Halliwell B, Esuvaranathan K, Wong KP.

Biochem Biophys Res Commun. 2015 May 15;460(4):938-43. doi: 10.1016/j.bbrc.2015.03.130. Epub 2015 Apr 1.

PMID:
25839656
22.

Adaptive responses to cool climate promotes persistence of a non-native lizard.

While GM, Williamson J, Prescott G, Horváthová T, Fresnillo B, Beeton NJ, Halliwell B, Michaelides S, Uller T.

Proc Biol Sci. 2015 Mar 22;282(1803):20142638. doi: 10.1098/rspb.2014.2638.

23.

Caenorhabditis elegans: What We Can and Cannot Learn from Aging Worms.

Gruber J, Chen CB, Fong S, Ng LF, Teo E, Halliwell B.

Antioxid Redox Signal. 2015 Jul 20;23(3):256-79. doi: 10.1089/ars.2014.6210. Epub 2015 Apr 29. Review.

PMID:
25544992
24.

The 'mitoflash' probe cpYFP does not respond to superoxide.

Schwarzländer M, Wagner S, Ermakova YG, Belousov VV, Radi R, Beckman JS, Buettner GR, Demaurex N, Duchen MR, Forman HJ, Fricker MD, Gems D, Halestrap AP, Halliwell B, Jakob U, Johnston IG, Jones NS, Logan DC, Morgan B, Müller FL, Nicholls DG, Remington SJ, Schumacker PT, Winterbourn CC, Sweetlove LJ, Meyer AJ, Dick TP, Murphy MP.

Nature. 2014 Oct 23;514(7523):E12-4. doi: 10.1038/nature13858. No abstract available.

25.

Cell culture, oxidative stress, and antioxidants: avoiding pitfalls.

Halliwell B.

Biomed J. 2014 May-Jun;37(3):99-105. doi: 10.4103/2319-4170.128725. Review.

26.

Does influenza A infection increase oxidative damage?

Ng MP, Lee JC, Loke WM, Yeo LL, Quek AM, Lim EC, Halliwell B, Seet RC.

Antioxid Redox Signal. 2014 Sep 1;21(7):1025-31. doi: 10.1089/ars.2014.5907. Epub 2014 Jul 21.

PMID:
24673169
27.

The mitochondria-targeted antioxidant MitoQ extends lifespan and improves healthspan of a transgenic Caenorhabditis elegans model of Alzheimer disease.

Ng LF, Gruber J, Cheah IK, Goo CK, Cheong WF, Shui G, Sit KP, Wenk MR, Halliwell B.

Free Radic Biol Med. 2014 Jun;71:390-401. doi: 10.1016/j.freeradbiomed.2014.03.003. Epub 2014 Mar 15.

28.

Does high-dose coenzyme Q10 improve oxidative damage and clinical outcomes in Parkinson's disease?

Seet RC, Lim EC, Tan JJ, Quek AM, Chow AW, Chong WL, Ng MP, Ong CN, Halliwell B.

Antioxid Redox Signal. 2014 Jul 10;21(2):211-7. doi: 10.1089/ars.2013.5801. Epub 2014 Feb 24.

PMID:
24410614
29.

Effects of lithium on age-related decline in mitochondrial turnover and function in Caenorhabditis elegans.

Tam ZY, Gruber J, Ng LF, Halliwell B, Gunawan R.

J Gerontol A Biol Sci Med Sci. 2014 Jul;69(7):810-20. doi: 10.1093/gerona/glt210. Epub 2014 Jan 7.

PMID:
24398558
30.

Variability in APOE genotype status in human-derived cell lines: a cause for concern in cell culture studies?

Schaffer S, Lam VY, Ernst IM, Huebbe P, Rimbach G, Halliwell B.

Genes Nutr. 2014 Jan;9(1):364. doi: 10.1007/s12263-013-0364-4. Epub 2013 Dec 3.

31.

Augmentation of 5-lipoxygenase activity and expression during dengue serotype-2 infection.

Loke WM, Chow AY, Lam Mok Sing K, Lee CY, Halliwell B, Lim EC, Quek AM, Ooi EE, Seet RC.

Virol J. 2013 Oct 30;10:322. doi: 10.1186/1743-422X-10-322.

32.

Mathematical modeling of the role of mitochondrial fusion and fission in mitochondrial DNA maintenance.

Tam ZY, Gruber J, Halliwell B, Gunawan R.

PLoS One. 2013 Oct 11;8(10):e76230. doi: 10.1371/journal.pone.0076230. eCollection 2013.

33.

Hydrogen sulfide is an endogenous regulator of aging in Caenorhabditis elegans.

Qabazard B, Li L, Gruber J, Peh MT, Ng LF, Kumar SD, Rose P, Tan CH, Dymock BW, Wei F, Swain SC, Halliwell B, Stürzenbaum SR, Moore PK.

Antioxid Redox Signal. 2014 Jun 1;20(16):2621-30. doi: 10.1089/ars.2013.5448. Epub 2013 Nov 21.

34.

Knockout of a putative ergothioneine transporter in Caenorhabditis elegans decreases lifespan and increases susceptibility to oxidative damage.

Cheah IK, Ong RL, Gruber J, Yew TS, Ng LF, Chen CB, Halliwell B.

Free Radic Res. 2013 Dec;47(12):1036-45. doi: 10.3109/10715762.2013.848354. Epub 2013 Oct 24.

PMID:
24074059
35.

Repression of the mitochondrial peroxiredoxin antioxidant system does not shorten life span but causes reduced fitness in Caenorhabditis elegans.

Ranjan M, Gruber J, Ng LF, Halliwell B.

Free Radic Biol Med. 2013 Oct;63:381-9. doi: 10.1016/j.freeradbiomed.2013.05.025. Epub 2013 May 28.

PMID:
23722165
36.

A high-fat and cholesterol diet causes fatty liver in guinea pigs. The role of iron and oxidative damage.

Ye P, Cheah IK, Halliwell B.

Free Radic Res. 2013 Aug;47(8):602-13. doi: 10.3109/10715762.2013.806796. Epub 2013 Jun 19.

PMID:
23692125
37.

An interview with Barry Halliwell.

Halliwell B.

Trends Pharmacol Sci. 2013 Jun;34(6):301-2. doi: 10.1016/j.tips.2013.04.002. Epub 2013 May 1. No abstract available.

PMID:
23642657
38.

Biomarkers of oxidative damage are elevated among individuals with high cardiovascular risk: refining subject selection strategies for antioxidant trials.

Seet RC, Quek AM, Lim EC, Halliwell B.

Free Radic Res. 2013 Apr;47(4):283-90. doi: 10.3109/10715762.2013.769215. Epub 2013 Feb 25.

PMID:
23343456
39.

High fat diets and pathology in the guinea pig. Atherosclerosis or liver damage?

Ye P, Cheah IK, Halliwell B.

Biochim Biophys Acta. 2013 Feb;1832(2):355-64. doi: 10.1016/j.bbadis.2012.11.008. Epub 2012 Nov 27. Review.

40.

Effects of hydrogen peroxide on wound healing in mice in relation to oxidative damage.

Loo AE, Wong YT, Ho R, Wasser M, Du T, Ng WT, Halliwell B.

PLoS One. 2012;7(11):e49215. doi: 10.1371/journal.pone.0049215. Epub 2012 Nov 13.

41.

Mitochondria-targeted antioxidants and metabolic modulators as pharmacological interventions to slow ageing.

Gruber J, Fong S, Chen CB, Yoong S, Pastorin G, Schaffer S, Cheah I, Halliwell B.

Biotechnol Adv. 2013 Sep-Oct;31(5):563-92. doi: 10.1016/j.biotechadv.2012.09.005. Epub 2012 Sep 27. Review.

PMID:
23022622
42.

Does iron inhibit calcification during atherosclerosis?

Rajendran R, Minqin R, Ronald JA, Rutt BK, Halliwell B, Watt F.

Free Radic Biol Med. 2012 Nov 1;53(9):1675-9. doi: 10.1016/j.freeradbiomed.2012.07.014. Epub 2012 Aug 17.

43.

Is mitochondrial DNA turnover slower than commonly assumed?

Poovathingal SK, Gruber J, Lakshmanan L, Halliwell B, Gunawan R.

Biogerontology. 2012 Oct;13(5):557-64. doi: 10.1007/s10522-012-9390-7. Epub 2012 Aug 3.

PMID:
22864459
44.

Acute effects of cigarette smoking on insulin resistance and arterial stiffness in young adults.

Seet RC, Loke WM, Khoo CM, Chew SE, Chong WL, Quek AM, Lim EC, Halliwell B.

Atherosclerosis. 2012 Sep;224(1):195-200. doi: 10.1016/j.atherosclerosis.2012.06.060. Epub 2012 Jul 20.

PMID:
22840427
45.

Effects of hydrogen peroxide in a keratinocyte-fibroblast co-culture model of wound healing.

Loo AE, Halliwell B.

Biochem Biophys Res Commun. 2012 Jun 29;423(2):253-8. doi: 10.1016/j.bbrc.2012.05.100. Epub 2012 May 24.

PMID:
22634311
46.

Sustained expression of heme oxygenase-1 alters iron homeostasis in nonerythroid cells.

Li C, Lönn ME, Xu X, Maghzal GJ, Frazer DM, Thomas SR, Halliwell B, Richardson DR, Anderson GJ, Stocker R.

Free Radic Biol Med. 2012 Jul 15;53(2):366-74. doi: 10.1016/j.freeradbiomed.2012.03.007. Epub 2012 Apr 18.

PMID:
22579918
47.

Free radicals and antioxidants: updating a personal view.

Halliwell B.

Nutr Rev. 2012 May;70(5):257-65. doi: 10.1111/j.1753-4887.2012.00476.x. Review.

PMID:
22537212
48.

Role of direct repeat and stem-loop motifs in mtDNA deletions: cause or coincidence?

Lakshmanan LN, Gruber J, Halliwell B, Gunawan R.

PLoS One. 2012;7(4):e35271. doi: 10.1371/journal.pone.0035271. Epub 2012 Apr 18.

49.

The antioxidant paradox: less paradoxical now?

Halliwell B.

Br J Clin Pharmacol. 2013 Mar;75(3):637-44. doi: 10.1111/j.1365-2125.2012.04272.x.

50.

Maximizing signal-to-noise ratio in the random mutation capture assay.

Poovathingal SK, Gruber J, Ng LF, Halliwell B, Gunawan R.

Nucleic Acids Res. 2012 Mar;40(5):e35. doi: 10.1093/nar/gkr1221. Epub 2011 Dec 17.

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