Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 111

1.

Impact of a clinical decision support tool on prediction of progression in early-stage dementia: a prospective validation study.

Bruun M, Frederiksen KS, Rhodius-Meester HFM, Baroni M, Gjerum L, Koikkalainen J, Urhemaa T, Tolonen A, van Gils M, Rueckert D, Dyremose N, Andersen BB, Lemstra AW, Hallikainen M, Kurl S, Herukka SK, Remes AM, Waldemar G, Soininen H, Mecocci P, van der Flier WM, Lötjönen J, Hasselbalch SG.

Alzheimers Res Ther. 2019 Mar 20;11(1):25. doi: 10.1186/s13195-019-0482-3.

2.

Effects of morphological family on word recognition in normal aging, mild cognitive impairment, and Alzheimer's disease.

Nikolaev A, Ashaie S, Hallikainen M, Hänninen T, Higby E, Hyun J, Lehtonen M, Soininen H.

Cortex. 2019 Jul;116:91-103. doi: 10.1016/j.cortex.2018.10.028. Epub 2018 Dec 11.

3.

Impact of a Clinical Decision Support Tool on Dementia Diagnostics in Memory Clinics: The PredictND Validation Study.

Bruun M, Frederiksen KS, Rhodius-Meester HFM, Baroni M, Gjerum L, Koikkalainen J, Urhemaa T, Tolonen A, van Gils M, Tong T, Guerrero R, Rueckert D, Dyremose N, Andersen BB, Simonsen AH, Lemstra A, Hallikainen M, Kurl S, Herukka SK, Remes AM, Waldemar G, Soininen H, Mecocci P, van der Flier WM, Lötjönen J, Hasselbalch SG.

Curr Alzheimer Res. 2019;16(2):91-101. doi: 10.2174/1567205016666190103152425.

PMID:
30605060
4.

Safety, tolerability and efficacy of the glutaminyl cyclase inhibitor PQ912 in Alzheimer's disease: results of a randomized, double-blind, placebo-controlled phase 2a study.

Scheltens P, Hallikainen M, Grimmer T, Duning T, Gouw AA, Teunissen CE, Wink AM, Maruff P, Harrison J, van Baal CM, Bruins S, Lues I, Prins ND.

Alzheimers Res Ther. 2018 Oct 12;10(1):107. doi: 10.1186/s13195-018-0431-6.

5.

The effects of acceptance and commitment therapy on eating behavior and diet delivered through face-to-face contact and a mobile app: a randomized controlled trial.

Järvelä-Reijonen E, Karhunen L, Sairanen E, Muotka J, Lindroos S, Laitinen J, Puttonen S, Peuhkuri K, Hallikainen M, Pihlajamäki J, Korpela R, Ermes M, Lappalainen R, Kolehmainen M.

Int J Behav Nutr Phys Act. 2018 Feb 27;15(1):22. doi: 10.1186/s12966-018-0654-8.

6.

Subtle Cognitive Impairment and Alzheimer's Disease-Type Pathological Changes in Cerebrospinal Fluid are Common Among Neurologically Healthy Subjects.

Haapalinna F, Kokki M, Jääskeläinen O, Hallikainen M, Helisalmi S, Koivisto A, Kokki H, Paajanen T, Penttinen J, Pikkarainen M, Rautiainen M, Soininen H, Solje E, Remes AM, Herukka SK.

J Alzheimers Dis. 2018;62(1):165-174. doi: 10.3233/JAD-170534.

PMID:
29439329
7.

Tolerability of ORM-12741 and effects on episodic memory in patients with Alzheimer's disease.

Rinne JO, Wesnes K, Cummings JL, Hakulinen P, Hallikainen M, Hänninen J, Murphy M, Riordan H, Scheinin M, Soininen H, Rouru J.

Alzheimers Dement (N Y). 2016 Dec 8;3(1):1-9. doi: 10.1016/j.trci.2016.11.004. eCollection 2017 Jan.

8.

The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimer's pathology.

Westwood S, Liu B, Baird AL, Anand S, Nevado-Holgado AJ, Newby D, Pikkarainen M, Hallikainen M, Kuusisto J, Streffer JR, Novak G, Blennow K, Andreasson U, Zetterberg H, Smith U, Laakso M, Soininen H, Lovestone S.

Alzheimers Res Ther. 2017 Apr 26;9(1):31. doi: 10.1186/s13195-017-0258-6. Review.

9.

Cardiorespiratory fitness and brain volumes in men and women in the FINGER study.

Pentikäinen H, Ngandu T, Liu Y, Savonen K, Komulainen P, Hallikainen M, Kivipelto M, Rauramaa R, Soininen H.

Age Ageing. 2017 Mar 1;46(2):310-313. doi: 10.1093/ageing/afw191.

PMID:
28064170
10.

Using the Disease State Fingerprint Tool for Differential Diagnosis of Frontotemporal Dementia and Alzheimer's Disease.

Muñoz-Ruiz MÁ, Hall A, Mattila J, Koikkalainen J, Herukka SK, Husso M, Hänninen T, Vanninen R, Liu Y, Hallikainen M, Lötjönen J, Remes AM, Alafuzoff I, Soininen H, Hartikainen P.

Dement Geriatr Cogn Dis Extra. 2016 Jul 22;6(2):313-329. eCollection 2016 May-Aug.

11.

High perceived stress is associated with unfavorable eating behavior in overweight and obese Finns of working age.

Järvelä-Reijonen E, Karhunen L, Sairanen E, Rantala S, Laitinen J, Puttonen S, Peuhkuri K, Hallikainen M, Juvonen K, Myllymäki T, Föhr T, Pihlajamäki J, Korpela R, Ermes M, Lappalainen R, Kolehmainen M.

Appetite. 2016 Aug 1;103:249-258. doi: 10.1016/j.appet.2016.04.023. Epub 2016 Apr 21.

PMID:
27108837
12.

[Will memory be lost with menopause--can an ageing woman be protected from memory disorder?].

Remes A, Tanila H, Hallikainen M.

Duodecim. 2015;131(16):1499-505. Review. Finnish.

PMID:
26485943
13.

Use of Anti-Dementia Drugs in Relation to Change in Cognition, Behavior, and Functioning in Alzheimer's Disease over a Three-Year Period: Kuopio ALSOVA Study.

Törmälehto SM, Martikainen JA, Väätäinen ST, Hallikainen IT, Hallikainen M, Bell JS, Koivisto AM.

J Alzheimers Dis. 2015;48(4):1033-41. doi: 10.3233/JAD-150092.

PMID:
26444756
14.

Dietary plant stanols or sterols neither accumulate in stenotic aortic valves nor influence their structure or inflammatory status.

Simonen P, Lommi J, Hallikainen M, Helske-Suihko S, Werkkala K, Kupari M, Kovanen PT, Gylling H.

Clin Nutr. 2015 Dec;34(6):1251-7. doi: 10.1016/j.clnu.2015.01.001. Epub 2015 Jan 7.

PMID:
25614126
15.

The use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey.

Bocchetta M, Galluzzi S, Kehoe PG, Aguera E, Bernabei R, Bullock R, Ceccaldi M, Dartigues JF, de Mendonça A, Didic M, Eriksdotter M, Félician O, Frölich L, Gertz HJ, Hallikainen M, Hasselbalch SG, Hausner L, Heuser I, Jessen F, Jones RW, Kurz A, Lawlor B, Lleo A, Martinez-Lage P, Mecocci P, Mehrabian S, Monsch A, Nobili F, Nordberg A, Rikkert MO, Orgogozo JM, Pasquier F, Peters O, Salmon E, Sánchez-Castellano C, Santana I, Sarazin M, Traykov L, Tsolaki M, Visser PJ, Wallin ÅK, Wilcock G, Wilkinson D, Wolf H, Yener G, Zekry D, Frisoni GB.

Alzheimers Dement. 2015 Feb;11(2):195-206.e1. doi: 10.1016/j.jalz.2014.06.006. Epub 2014 Aug 20.

PMID:
25150733
16.

Cholesterol metabolism and serum non-cholesterol sterols: summary of 13 plant stanol ester interventions.

Hallikainen M, Simonen P, Gylling H.

Lipids Health Dis. 2014 Apr 27;13:72. doi: 10.1186/1476-511X-13-72.

17.

CERAD Neuropsychological Total Scores Reflect Cortical Thinning in Prodromal Alzheimer's Disease.

Paajanen T, Hänninen T, Aitken A, Hallikainen M, Westman E, Wahlund LO, Sobow T, Mecocci P, Tsolaki M, Vellas B, Muehlboeck S, Spenger C, Lovestone S, Simmons A, Soininen H; AddNeuroMed Consortium.

Dement Geriatr Cogn Dis Extra. 2013 Nov 30;3(1):446-58. doi: 10.1159/000356725. eCollection 2013 Jan.

18.

Diet and cardiovascular health in asymptomatic normo- and mildly-to-moderately hypercholesterolemic participants - baseline data from the BLOOD FLOW intervention study.

Hallikainen M, Halonen J, Konttinen J, Lindholm H, Simonen P, Nissinen MJ, Gylling H.

Nutr Metab (Lond). 2013 Oct 7;10(1):62. doi: 10.1186/1743-7075-10-62.

19.

CERAD neuropsychological compound scores are accurate in detecting prodromal alzheimer's disease: a prospective AddNeuroMed study.

Paajanen T, Hänninen T, Tunnard C, Hallikainen M, Mecocci P, Sobow T, Tsolaki M, Vellas B, Lovestone S, Soininen H.

J Alzheimers Dis. 2014;39(3):679-90. doi: 10.3233/JAD-122110.

PMID:
24246420
20.
21.

Validity of dementia and Alzheimer's disease diagnoses in Finnish national registers.

Solomon A, Ngandu T, Soininen H, Hallikainen MM, Kivipelto M, Laatikainen T.

Alzheimers Dement. 2014 May;10(3):303-9. doi: 10.1016/j.jalz.2013.03.004. Epub 2013 Jul 10.

PMID:
23849592
22.

The effects of plant stanol ester consumption on arterial stiffness and endothelial function in adults: a randomised controlled clinical trial.

Gylling H, Halonen J, Lindholm H, Konttinen J, Simonen P, Nissinen MJ, Savolainen A, Talvi A, Hallikainen M.

BMC Cardiovasc Disord. 2013 Jul 10;13:50. doi: 10.1186/1471-2261-13-50.

23.

Cholesterol metabolism and weight reduction in subjects with mild obstructive sleep apnoea: a randomised, controlled study.

Hallikainen M, Tuomilehto H, Martikainen T, Vanninen E, Seppä J, Kokkarinen J, Randell J, Gylling H.

Cholesterol. 2013;2013:769457. doi: 10.1155/2013/769457. Epub 2013 May 16.

24.

[Posterior variant of Alzheimer's disease and other atypical symptom pictures].

Remes AM, Vanninen R, Jokinen H, Hallikainen M, Erkinjuntti T.

Duodecim. 2013;129(3):244-50. Review. Finnish.

PMID:
23457775
25.

Application of the PredictAD software tool to predict progression in patients with mild cognitive impairment.

Simonsen AH, Mattila J, Hejl AM, Frederiksen KS, Herukka SK, Hallikainen M, van Gils M, Lötjönen J, Soininen H, Waldemar G.

Dement Geriatr Cogn Disord. 2012;34(5-6):344-50. doi: 10.1159/000345554. Epub 2012 Dec 6.

26.

Bilberries reduce low-grade inflammation in individuals with features of metabolic syndrome.

Kolehmainen M, Mykkänen O, Kirjavainen PV, Leppänen T, Moilanen E, Adriaens M, Laaksonen DE, Hallikainen M, Puupponen-Pimiä R, Pulkkinen L, Mykkänen H, Gylling H, Poutanen K, Törrönen R.

Mol Nutr Food Res. 2012 Oct;56(10):1501-10. doi: 10.1002/mnfr.201200195. Epub 2012 Sep 7.

PMID:
22961907
27.

Mild cognitive impairment associates with concurrent decreases in serum cholesterol and cholesterol-related lipoprotein subclasses.

Tukiainen T, Jylänki P, Mäkinen VP, Gröhn O, Hallikainen M, Soininen H, Kivipelto M, Kaski K, Groop PH, Savolainen MJ, Pirttilä T, Soininen P, Ala-Korpela M.

J Nutr Health Aging. 2012 Jul;16(7):631-5.

PMID:
22836705
28.

Conjugated bile acids associate with altered rates of glucose and lipid oxidation after Roux-en-Y gastric bypass.

Simonen M, Dali-Youcef N, Kaminska D, Venesmaa S, Käkelä P, Pääkkönen M, Hallikainen M, Kolehmainen M, Uusitupa M, Moilanen L, Laakso M, Gylling H, Patti ME, Auwerx J, Pihlajamäki J.

Obes Surg. 2012 Sep;22(9):1473-80. doi: 10.1007/s11695-012-0673-5.

29.

Cortical thickness in frontotemporal dementia, mild cognitive impairment, and Alzheimer's disease.

Hartikainen P, Räsänen J, Julkunen V, Niskanen E, Hallikainen M, Kivipelto M, Vanninen R, Remes AM, Soininen H.

J Alzheimers Dis. 2012;30(4):857-74. doi: 10.3233/JAD-2012-112060.

PMID:
22466003
30.

Evolution of global and local grey matter atrophy on serial MRI scans during the progression from MCI to AD.

Spulber G, Niskanen E, Macdonald S, Kivipelto M, Padilla DF, Julkunen V, Hallikainen M, Vanninen R, Wahlund LO, Soininen H.

Curr Alzheimer Res. 2012 May;9(4):516-24.

PMID:
22191564
31.

New insights into Alzheimer's disease progression: a combined TMS and structural MRI study.

Niskanen E, Könönen M, Määttä S, Hallikainen M, Kivipelto M, Casarotto S, Massimini M, Vanninen R, Mervaala E, Karhu J, Soininen H.

PLoS One. 2011;6(10):e26113. doi: 10.1371/journal.pone.0026113. Epub 2011 Oct 12. Erratum in: PLoS One. 2014;9(2):e91271.

32.

Serum and lipoprotein sitostanol and non-cholesterol sterols after an acute dose of plant stanol ester on its long-term consumption.

Gylling H, Hallikainen M, Simonen P, Miettinen HE, Nissinen MJ, Miettinen TA.

Eur J Nutr. 2012 Aug;51(5):615-22. doi: 10.1007/s00394-011-0249-5. Epub 2011 Sep 23.

PMID:
21947207
33.

Plant stanol esters lower LDL cholesterol level in statin-treated subjects with type 1 diabetes by interfering the absorption and synthesis of cholesterol.

Hallikainen M, Kurl S, Laakso M, Miettinen TA, Gylling H.

Atherosclerosis. 2011 Aug;217(2):473-8. doi: 10.1016/j.atherosclerosis.2011.03.041. Epub 2011 Apr 5.

PMID:
21514589
34.

Metabolome in progression to Alzheimer's disease.

Orešič M, Hyötyläinen T, Herukka SK, Sysi-Aho M, Mattila I, Seppänan-Laakso T, Julkunen V, Gopalacharyulu PV, Hallikainen M, Koikkalainen J, Kivipelto M, Helisalmi S, Lötjönen J, Soininen H.

Transl Psychiatry. 2011 Dec 13;1:e57. doi: 10.1038/tp.2011.55.

35.

Cholesterol synthesis is increased and absorption decreased in non-alcoholic fatty liver disease independent of obesity.

Simonen P, Kotronen A, Hallikainen M, Sevastianova K, Makkonen J, Hakkarainen A, Lundbom N, Miettinen TA, Gylling H, Yki-Järvinen H.

J Hepatol. 2011 Jan;54(1):153-9. doi: 10.1016/j.jhep.2010.05.037. Epub 2010 Aug 22.

PMID:
20947198
36.

Plasma Abeta42 and Abeta40 as markers of cognitive change in follow-up: a prospective, longitudinal, population-based cohort study.

Seppälä TT, Herukka SK, Hänninen T, Tervo S, Hallikainen M, Soininen H, Pirttilä T.

J Neurol Neurosurg Psychiatry. 2010 Oct;81(10):1123-7. doi: 10.1136/jnnp.2010.205757. Epub 2010 May 16.

37.

Insulin sensitivity regulates cholesterol metabolism to a greater extent than obesity: lessons from the METSIM Study.

Gylling H, Hallikainen M, Pihlajamäki J, Simonen P, Kuusisto J, Laakso M, Miettinen TA.

J Lipid Res. 2010 Aug;51(8):2422-7. doi: 10.1194/jlr.P006619. Epub 2010 May 1.

38.

Differences in cortical thickness in healthy controls, subjects with mild cognitive impairment, and Alzheimer's disease patients: a longitudinal study.

Julkunen V, Niskanen E, Koikkalainen J, Herukka SK, Pihlajamäki M, Hallikainen M, Kivipelto M, Muehlboeck S, Evans AC, Vanninen R, Hilkka Soininen.

J Alzheimers Dis. 2010;21(4):1141-51.

PMID:
21504134
39.

Relation of non-cholesterol sterols to coronary risk factors and carotid intima-media thickness: the Cardiovascular Risk in Young Finns Study.

Miettinen TA, Gylling H, Hallikainen M, Juonala M, Räsänen L, Viikari J, Raitakari OT.

Atherosclerosis. 2010 Apr;209(2):592-7. doi: 10.1016/j.atherosclerosis.2009.10.013. Epub 2009 Oct 20.

PMID:
19963215
40.

Diffusion tensor imaging and tract-based spatial statistics in Alzheimer's disease and mild cognitive impairment.

Liu Y, Spulber G, Lehtimäki KK, Könönen M, Hallikainen I, Gröhn H, Kivipelto M, Hallikainen M, Vanninen R, Soininen H.

Neurobiol Aging. 2011 Sep;32(9):1558-71. doi: 10.1016/j.neurobiolaging.2009.10.006. Epub 2009 Nov 12.

PMID:
19913331
41.

Cortical thickness analysis to detect progressive mild cognitive impairment: a reference to Alzheimer's disease.

Julkunen V, Niskanen E, Muehlboeck S, Pihlajamäki M, Könönen M, Hallikainen M, Kivipelto M, Tervo S, Vanninen R, Evans A, Soininen H.

Dement Geriatr Cogn Disord. 2009;28(5):404-12. doi: 10.1159/000256274. Epub 2009 Nov 10.

42.

Very high plant stanol intake and serum plant stanols and non-cholesterol sterols.

Gylling H, Hallikainen M, Nissinen MJ, Simonen P, Miettinen TA.

Eur J Nutr. 2010 Mar;49(2):111-7. doi: 10.1007/s00394-009-0055-5. Epub 2009 Sep 23.

PMID:
19774436
43.

The effect of a very high daily plant stanol ester intake on serum lipids, carotenoids, and fat-soluble vitamins.

Gylling H, Hallikainen M, Nissinen MJ, Miettinen TA.

Clin Nutr. 2010 Feb;29(1):112-8. doi: 10.1016/j.clnu.2009.08.005. Epub 2009 Aug 26.

PMID:
19709787
44.

Olfactory identification in non-demented elderly population and in mild cognitive impairment: a comparison of performance in clinical odor identification versus Boston Naming Test.

Laakso MP, Tervo S, Hänninen T, Vanhanen M, Hallikainen M, Soininen H.

J Neural Transm (Vienna). 2009 Jul;116(7):891-5. doi: 10.1007/s00702-009-0235-8. Epub 2009 May 7.

PMID:
19551462
45.

The metabolism of plant sterols is disturbed in postmenopausal women with coronary artery disease.

Gylling H, Hallikainen M, Rajaratnam RA, Simonen P, Pihlajamäki J, Laakso M, Miettinen TA.

Metabolism. 2009 Mar;58(3):401-7. doi: 10.1016/j.metabol.2008.10.015.

PMID:
19217458
46.

Twenty-one year tracking of serum non-cholesterol sterols. The Cardiovascular Risk in Young Finns study.

Miettinen TA, Hallikainen M, Raitakari OT, Viikari J, Gylling H.

Nutr Metab Cardiovasc Dis. 2009 Oct;19(8):525-31. doi: 10.1016/j.numecd.2008.10.009. Epub 2009 Jan 29.

PMID:
19185477
47.

Long-term consumption of plant stanol and sterol esters, vascular function and genetic regulation.

Gylling H, Hallikainen M, Raitakari OT, Laakso M, Vartiainen E, Salo P, Korpelainen V, Sundvall J, Miettinen TA.

Br J Nutr. 2009 Jun;101(11):1688-95. doi: 10.1017/S0007114508116300. Epub 2008 Nov 19.

PMID:
19019257
48.

PET amyloid ligand [11C]PIB uptake and cerebrospinal fluid beta-amyloid in mild cognitive impairment.

Koivunen J, Pirttilä T, Kemppainen N, Aalto S, Herukka SK, Jauhianen AM, Hänninen T, Hallikainen M, Någren K, Rinne JO, Soininen H.

Dement Geriatr Cogn Disord. 2008;26(4):378-83. doi: 10.1159/000163927. Epub 2008 Oct 16.

PMID:
18931497
49.

Whole brain atrophy rate predicts progression from MCI to Alzheimer's disease.

Spulber G, Niskanen E, MacDonald S, Smilovici O, Chen K, Reiman EM, Jauhiainen AM, Hallikainen M, Tervo S, Wahlund LO, Vanninen R, Kivipelto M, Soininen H.

Neurobiol Aging. 2010 Sep;31(9):1601-5. doi: 10.1016/j.neurobiolaging.2008.08.018. Epub 2008 Oct 1.

PMID:
18829136
50.

A multi-metabolite analysis of serum by 1H NMR spectroscopy: early systemic signs of Alzheimer's disease.

Tukiainen T, Tynkkynen T, Mäkinen VP, Jylänki P, Kangas A, Hokkanen J, Vehtari A, Gröhn O, Hallikainen M, Soininen H, Kivipelto M, Groop PH, Kaski K, Laatikainen R, Soininen P, Pirttilä T, Ala-Korpela M.

Biochem Biophys Res Commun. 2008 Oct 24;375(3):356-61. doi: 10.1016/j.bbrc.2008.08.007. Epub 2008 Aug 26.

PMID:
18700135

Supplemental Content

Loading ...
Support Center