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Items: 1 to 50 of 182

1.

Single cell measurement of calpain activity in neutrophils reveals link to cytosolic Ca2+ elevation and individual phagocytotic events.

Jennings S, Hallett MB.

Biochem Biophys Res Commun. 2019 Jul 12;515(1):163-168. doi: 10.1016/j.bbrc.2019.05.125. Epub 2019 May 24.

PMID:
31130232
2.

Neutrophil Cell Shape Change: Mechanism and Signalling during Cell Spreading and Phagocytosis.

Roberts RE, Hallett MB.

Int J Mol Sci. 2019 Mar 19;20(6). pii: E1383. doi: 10.3390/ijms20061383. Review.

3.

Corrigendum to "Defective rapid cell shape and transendothelial migration by calpain-1 null neutrophils" [Biochemical and Biophysical Research Communications 506 (2018) pp. 1065-1070].

Ishak R, Hallett MB.

Biochem Biophys Res Commun. 2019 Jan 22;508(4):1292. doi: 10.1016/j.bbrc.2018.12.085. Epub 2018 Dec 17. No abstract available.

PMID:
30573359
4.

Defective rapid cell shape and transendothelial migration by calpain-1 null neutrophils.

Ishak R, Hallett MB.

Biochem Biophys Res Commun. 2018 Dec 2;506(4):1065-1070. doi: 10.1016/j.bbrc.2018.10.174. Epub 2018 Nov 5. Erratum in: Biochem Biophys Res Commun. 2019 Jan 22;508(4):1292.

PMID:
30409431
5.

Phagocytosis and Motility in Human Neutrophils is Competent but Compromised by Pharmacological Inhibition of Ezrin Phosphorylation.

Roberts RE, Elumalai GL, Hallett MB.

Curr Mol Pharmacol. 2018;11(4):305-315. doi: 10.2174/1874467211666180516100613.

PMID:
29766831
6.

Topographical interrogation of the living cell surface reveals its role in rapid cell shape changes during phagocytosis and spreading.

Jumaa MAA, Dewitt S, Hallett MB.

Sci Rep. 2017 Aug 29;7(1):9790. doi: 10.1038/s41598-017-09761-6.

7.

Conformationally restricted calpain inhibitors.

Adams SE, Robinson EJ, Miller DJ, Rizkallah PJ, Hallett MB, Allemann RK.

Chem Sci. 2015 Dec 1;6(12):6865-6871. doi: 10.1039/c5sc01158b. Epub 2015 Aug 24.

8.

Active calpain in phagocytically competent human neutrophils: electroinjection of fluorogenic calpain substrate.

Campbell JS, Hallett MB.

Biochem Biophys Res Commun. 2015 Feb 13;457(3):341-6. doi: 10.1016/j.bbrc.2014.12.113. Epub 2015 Jan 7.

PMID:
25576867
9.

The structural basis of differential inhibition of human calpain by indole and phenyl α-mercaptoacrylic acids.

Adams SE, Rizkallah PJ, Miller DJ, Robinson EJ, Hallett MB, Allemann RK.

J Struct Biol. 2014 Sep;187(3):236-241. doi: 10.1016/j.jsb.2014.07.004. Epub 2014 Jul 30.

PMID:
25086406
10.

Minimal impact electro-injection of cells undergoing dynamic shape change reveals calpain activation.

Lewis KJ, Masterman B, Laffafian I, Dewitt S, Campbell JS, Hallett MB.

Biochim Biophys Acta. 2014 Jun;1843(6):1182-7. doi: 10.1016/j.bbamcr.2014.02.020. Epub 2014 Mar 7.

11.

Microinjection methods for neutrophils.

Laffafian I, Lewis KJ, Masterman KB, Hallett MB.

Methods Mol Biol. 2014;1124:181-7. doi: 10.1007/978-1-62703-845-4_11.

PMID:
24504952
12.

Optical methods for the measurement and manipulation of cytosolic calcium signals in neutrophils.

Hallett MB, Al-Jumaa M, Dewitt S.

Methods Mol Biol. 2014;1124:107-20. doi: 10.1007/978-1-62703-845-4_8.

PMID:
24504949
13.

Calpain-1 inhibitors for selective treatment of rheumatoid arthritis: what is the future?

Miller DJ, Adams SE, Hallett MB, Allemann RK.

Future Med Chem. 2013 Nov;5(17):2057-74. doi: 10.4155/fmc.13.172. Review.

PMID:
24215346
14.

Ca²⁺ and calpain control membrane expansion during the rapid cell spreading of neutrophils.

Dewitt S, Francis RJ, Hallett MB.

J Cell Sci. 2013 Oct 15;126(Pt 20):4627-35. doi: 10.1242/jcs.124917. Epub 2013 Aug 13.

15.

Transforming growth factor-β1 (TGF-β1)-stimulated fibroblast to myofibroblast differentiation is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization in lipid rafts.

Midgley AC, Rogers M, Hallett MB, Clayton A, Bowen T, Phillips AO, Steadman R.

J Biol Chem. 2013 May 24;288(21):14824-38. doi: 10.1074/jbc.M113.451336. Epub 2013 Apr 15.

16.

Ca2+ activation of cytosolic calpain induces the transition from apoptosis to necrosis in neutrophils with externalized phosphatidylserine.

Francis RJ, Kotecha S, Hallett MB.

J Leukoc Biol. 2013 Jan;93(1):95-100. doi: 10.1189/jlb.0412212. Epub 2012 Oct 22.

PMID:
23089743
17.

Extracellular ATP induces spikes in cytosolic free Ca(2+) but not in NADPH oxidase activity in neutrophils.

Brasen JC, Olsen LF, Hallett MB.

Biochim Biophys Acta. 2011 Aug;1813(8):1446-52. doi: 10.1016/j.bbamcr.2011.05.002. Epub 2011 May 8.

18.

In vivo functional analysis and genetic modification of in vitro-derived mouse neutrophils.

McDonald JU, Cortini A, Rosas M, Fossati-Jimack L, Ling GS, Lewis KJ, Dewitt S, Liddiard K, Brown GD, Jones SA, Hallett MB, Botto M, Taylor PR.

FASEB J. 2011 Jun;25(6):1972-82. doi: 10.1096/fj.10-178517. Epub 2011 Mar 2.

PMID:
21368104
19.

A trick of the light: the optical properties of living cytoplasm which can mislead.

Hallett MB, Dewitt S.

Integr Biol (Camb). 2011 Mar;3(3):180-4. doi: 10.1039/c0ib00039f. Epub 2011 Jan 4. Review.

PMID:
21206939
20.

Optical complexities of living cytoplasm--implications for live cell imaging and photo-micromanipulation techniques.

Dewitt S, Hallett MB.

J Microsc. 2011 Mar;241(3):221-4. doi: 10.1111/j.1365-2818.2010.03451.x. Epub 2010 Sep 27. Review.

21.

A reporter of UV intensity delivered to the cytosol during photolytic uncaging.

Brasen JC, Dewitt S, Hallett MB.

Biophys J. 2010 Apr 7;98(7):L25-7. doi: 10.1016/j.bpj.2009.12.4271.

22.

Cell surface topology creates high Ca2+ signalling microdomains.

Brasen JC, Olsen LF, Hallett MB.

Cell Calcium. 2010 Apr;47(4):339-49. doi: 10.1016/j.ceca.2010.01.005. Epub 2010 Feb 13.

23.

Fantastic Ca2+ "z-waves" fade out quietly.

Hallett MB, Lebiedz D, Mommer MS, Reble C, Saltmarsh EJ.

Cell Calcium. 2009 Jul;46(1):85-6. doi: 10.1016/j.ceca.2009.04.003. Epub 2009 May 17. Review.

PMID:
19450875
24.

Translocation or just location? Pseudopodia affect fluorescent signals.

Dewitt S, Darley RL, Hallett MB.

J Cell Biol. 2009 Jan 26;184(2):197-203. doi: 10.1083/jcb.200806047.

25.

Stopping the traffic: a route to arthritis therapy.

Hallett MB, Williams AS.

Eur J Immunol. 2008 Oct;38(10):2650-3. doi: 10.1002/eji.200838786.

26.

Perturbing plasma membrane hemichannels attenuates calcium signalling in cardiac cells and HeLa cells expressing connexins.

Verma V, Hallett MB, Leybaert L, Martin PE, Evans WH.

Eur J Cell Biol. 2009 Feb;88(2):79-90. doi: 10.1016/j.ejcb.2008.08.005. Epub 2008 Oct 31.

PMID:
18951659
27.

Chemotaxis and the cell surface-area problem.

Hallett MB, von Ruhland CJ, Dewitt S.

Nat Rev Mol Cell Biol. 2008 Aug;9(8):662; author reply 662. doi: 10.1038/nrm2419-c1. No abstract available.

PMID:
18648376
28.

Immature circulating neutrophils in sepsis have impaired phagocytosis and calcium signaling.

Taneja R, Sharma AP, Hallett MB, Findlay GP, Morris MR.

Shock. 2008 Dec;30(6):618-22. doi: 10.1097/SHK.0b013e318173ef9c.

PMID:
18496237
29.

Optical methods for the measurement and manipulation of cytosolic free calcium in neutrophils.

Hillson EJ, Dewitt S, Hallett MB.

Methods Mol Biol. 2007;412:125-37. doi: 10.1007/978-1-59745-467-4_10.

PMID:
18453110
30.

Ironing out the wrinkles of neutrophil phagocytosis.

Hallett MB, Dewitt S.

Trends Cell Biol. 2007 May;17(5):209-14. Epub 2007 Mar 12.

PMID:
17350842
31.
32.

Phagocytosis of optically-trapped particles: delivery of the pure phagocytic signal.

Hallett MB.

Cell Res. 2006 Nov;16(11):852-4. No abstract available.

33.
34.
35.

Reduced iC3b-mediated phagocytotic capacity of pulmonary neutrophils in cystic fibrosis.

Morris MR, Doull IJ, Dewitt S, Hallett MB.

Clin Exp Immunol. 2005 Oct;142(1):68-75.

36.
37.

Signalling shutdown strategies in aging immune cells.

Ayub K, Hallett MB.

Aging Cell. 2004 Aug;3(4):145-9. Review.

38.

Ca influx shutdown in neutrophils induced by Fas (CD95) cross-linking.

Ayub K, Laffafian I, Dewitt S, Hallett MB.

Immunology. 2004 Jul;112(3):454-60. Erratum in: Immunology. 2007 Dec;122(4):634.

39.

Ca(2+), calpain and 3-phosphorylated phosphatidyl inositides; decision-making signals in neutrophils as potential targets for therapeutics.

Tian W, Dewitt S, Laffafian I, Hallett MB.

J Pharm Pharmacol. 2004 May;56(5):565-71. Review.

PMID:
15142332
40.

Adhesion and signaling by B cell-derived exosomes: the role of integrins.

Clayton A, Turkes A, Dewitt S, Steadman R, Mason MD, Hallett MB.

FASEB J. 2004 Jun;18(9):977-9. Epub 2004 Apr 1.

PMID:
15059973
41.

Ca2+ influx shutdown during neutrophil apoptosis: importance and possible mechanism.

Ayub K, Hallett MB.

Immunology. 2004 Jan;111(1):8-12. Review. No abstract available.

43.
44.

Detection and visualization of oxidase activity in phagocytes.

Hallett MB, Cole C, Dewitt S.

Methods Mol Biol. 2003;225:61-7. Review. No abstract available.

PMID:
12769474
45.

Cytosolic Ca2+ measurement and imaging in inflammatory cells.

Dewitt S, Laffafian I, Morris MR, Hallett MB.

Methods Mol Biol. 2003;225:47-59. Review. No abstract available.

PMID:
12769473
46.

Phagocytosis by inflammatory phagocytes: experimental strategies for stimulation and quantification.

Morris MR, Dewitt S, Laffafian I, Hallett MB.

Methods Mol Biol. 2003;225:35-46. Review. No abstract available.

PMID:
12769472
47.

Intranuclear Ca2+ signals within individual nuclear lobes of neutrophils.

Hodges R, Laffafian I, Hallett MB.

Cell Biol Int. 2003;27(5):395-402.

PMID:
12758086
48.

Holding back neutrophil aggression; the oxidase has potential.

Hallett MB.

Clin Exp Immunol. 2003 May;132(2):181-4. Review. No abstract available.

49.
50.

Factor VIIa induced release of von Willebrand factor from human umbilical vein endothelial cells by a tyrosine kinase dependent pathway.

Brown SA, Bowen DJ, Hallett MB, Giddings JC, Collins PW.

Thromb Haemost. 2002 Jun;87(6):1057-61.

PMID:
12083486

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