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Items: 1 to 50 of 193

1.

Human MX2/MxB: a Potent Interferon-Induced Postentry Inhibitor of Herpesviruses and HIV-1.

Staeheli P, Haller O.

J Virol. 2018 Nov 27;92(24). pii: e00709-18. doi: 10.1128/JVI.00709-18. Print 2018 Dec 15. Review.

2.

The Discovery of the Antiviral Resistance Gene Mx: A Story of Great Ideas, Great Failures, and Some Success.

Haller O, Arnheiter H, Pavlovic J, Staeheli P.

Annu Rev Virol. 2018 Sep 29;5(1):33-51. doi: 10.1146/annurev-virology-092917-043525. Epub 2018 Jun 29. Review.

PMID:
29958082
3.

Follow-up after endovascular aortic aneurysm repair can be stratified based on first postoperative imaging.

Baderkhan H, Haller O, Wanhainen A, Björck M, Mani K.

Br J Surg. 2018 May;105(6):709-718. doi: 10.1002/bjs.10766. Epub 2018 Mar 26.

PMID:
29579326
4.

In vivo evasion of MxA by avian influenza viruses requires human signature in the viral nucleoprotein.

Deeg CM, Hassan E, Mutz P, Rheinemann L, Götz V, Magar L, Schilling M, Kallfass C, Nürnberger C, Soubies S, Kochs G, Haller O, Schwemmle M, Staeheli P.

J Exp Med. 2017 May 1;214(5):1239-1248. doi: 10.1084/jem.20161033. Epub 2017 Apr 10.

5.

Corrigendum: Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import.

Götz V, Magar L, Dornfeld D, Giese S, Pohlmann A, Höper D, Kong BW, Jans DA, Beer M, Haller O, Schwemmle M.

Sci Rep. 2016 May 9;6:25428. doi: 10.1038/srep25428. No abstract available.

6.

Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import.

Götz V, Magar L, Dornfeld D, Giese S, Pohlmann A, Höper D, Kong BW, Jans DA, Beer M, Haller O, Schwemmle M.

Sci Rep. 2016 Mar 18;6:23138. doi: 10.1038/srep23138. Erratum in: Sci Rep. 2016 May 09;6:25428.

7.

A tribute to Jean Lindenmann, co-discoverer of interferon (1924-2015).

Haller O.

Cytokine. 2015 Nov;76(1):113-5. doi: 10.1016/j.cyto.2015.02.029. Epub 2015 Apr 30.

PMID:
25937629
8.

Jean Lindenmann: from viral interference to interferon and beyond (1924-2015).

Haller O.

J Interferon Cytokine Res. 2015 Apr;35(4):239-41. doi: 10.1089/jir.2015.1500. No abstract available.

PMID:
25839326
9.

Mx GTPases: dynamin-like antiviral machines of innate immunity.

Haller O, Staeheli P, Schwemmle M, Kochs G.

Trends Microbiol. 2015 Mar;23(3):154-63. doi: 10.1016/j.tim.2014.12.003. Epub 2015 Jan 6. Review.

PMID:
25572883
10.

The nucleoprotein of newly emerged H7N9 influenza A virus harbors a unique motif conferring resistance to antiviral human MxA.

Riegger D, Hai R, Dornfeld D, Mänz B, Leyva-Grado V, Sánchez-Aparicio MT, Albrecht RA, Palese P, Haller O, Schwemmle M, García-Sastre A, Kochs G, Schmolke M.

J Virol. 2015 Feb;89(4):2241-52. doi: 10.1128/JVI.02406-14. Epub 2014 Dec 10.

11.

Structural requirements for the antiviral activity of the human MxA protein against Thogoto and influenza A virus.

Patzina C, Haller O, Kochs G.

J Biol Chem. 2014 Feb 28;289(9):6020-7. doi: 10.1074/jbc.M113.543892. Epub 2014 Jan 21.

12.

Dynamins are forever: MxB inhibits HIV-1.

Haller O.

Cell Host Microbe. 2013 Oct 16;14(4):371-3. doi: 10.1016/j.chom.2013.10.002.

13.

Emergence of a C-terminal seven-amino-acid elongation of NS1 in around 1950 conferred a minor growth advantage to former seasonal influenza A viruses.

Lohrmann F, Dijkman R, Stertz S, Thiel V, Haller O, Staeheli P, Kochs G.

J Virol. 2013 Oct;87(20):11300-3. doi: 10.1128/JVI.01271-13. Epub 2013 Aug 7.

14.

Pandemic influenza A viruses escape from restriction by human MxA through adaptive mutations in the nucleoprotein.

Mänz B, Dornfeld D, Götz V, Zell R, Zimmermann P, Haller O, Kochs G, Schwemmle M.

PLoS Pathog. 2013 Mar;9(3):e1003279. doi: 10.1371/journal.ppat.1003279. Epub 2013 Mar 28.

15.

Evolution-guided identification of antiviral specificity determinants in the broadly acting interferon-induced innate immunity factor MxA.

Mitchell PS, Patzina C, Emerman M, Haller O, Malik HS, Kochs G.

Cell Host Microbe. 2012 Oct 18;12(4):598-604. doi: 10.1016/j.chom.2012.09.005.

16.

[Implementation of the laryngeal tube for prehospital airway management: training of 1,069 emergency physicians and paramedics].

Schalk R, Auhuber T, Haller O, Latasch L, Wetzel S, Weber CF, Ruesseler M, Byhahn C.

Anaesthesist. 2012 Jan;61(1):35-40. doi: 10.1007/s00101-011-1966-0. Epub 2012 Jan 25. German.

PMID:
22273823
17.

Altered receptor specificity and fusion activity of the haemagglutinin contribute to high virulence of a mouse-adapted influenza A virus.

Koerner I, Matrosovich MN, Haller O, Staeheli P, Kochs G.

J Gen Virol. 2012 May;93(Pt 5):970-9. doi: 10.1099/vir.0.035782-0. Epub 2012 Jan 18.

PMID:
22258863
18.

Structure of myxovirus resistance protein a reveals intra- and intermolecular domain interactions required for the antiviral function.

Gao S, von der Malsburg A, Dick A, Faelber K, Schröder GF, Haller O, Kochs G, Daumke O.

Immunity. 2011 Oct 28;35(4):514-25. doi: 10.1016/j.immuni.2011.07.012. Epub 2011 Sep 29.

19.

Stalk domain of the dynamin-like MxA GTPase protein mediates membrane binding and liposome tubulation via the unstructured L4 loop.

von der Malsburg A, Abutbul-Ionita I, Haller O, Kochs G, Danino D.

J Biol Chem. 2011 Oct 28;286(43):37858-65. doi: 10.1074/jbc.M111.249037. Epub 2011 Sep 7.

20.

Structure of the MxA stalk elucidates the assembly of ring-like units of an antiviral module.

Daumke O, Gao S, von der Malsburg A, Haller O, Kochs G.

Small GTPases. 2010 Jul;1(1):62-64.

21.

The viral nucleoprotein determines Mx sensitivity of influenza A viruses.

Zimmermann P, Mänz B, Haller O, Schwemmle M, Kochs G.

J Virol. 2011 Aug;85(16):8133-40. doi: 10.1128/JVI.00712-11. Epub 2011 Jun 15.

22.

Human MxA protein: an interferon-induced dynamin-like GTPase with broad antiviral activity.

Haller O, Kochs G.

J Interferon Cytokine Res. 2011 Jan;31(1):79-87. doi: 10.1089/jir.2010.0076. Epub 2010 Dec 19. Review.

PMID:
21166595
23.

Neurogenic characteristics of placental stem cells in preeclampsia.

Portmann-Lanz CB, Baumann MU, Mueller M, Wagner AM, Weiss S, Haller O, Sager R, Reinhart U, Surbek DV.

Am J Obstet Gynecol. 2010 Oct;203(4):399.e1-7. doi: 10.1016/j.ajog.2010.06.054. Epub 2010 Aug 17.

PMID:
20723871
24.

Dynamin-like MxA GTPase: structural insights into oligomerization and implications for antiviral activity.

Haller O, Gao S, von der Malsburg A, Daumke O, Kochs G.

J Biol Chem. 2010 Sep 10;285(37):28419-24. doi: 10.1074/jbc.R110.145839. Epub 2010 Jun 10. Review.

25.

Structural basis of oligomerization in the stalk region of dynamin-like MxA.

Gao S, von der Malsburg A, Paeschke S, Behlke J, Haller O, Kochs G, Daumke O.

Nature. 2010 May 27;465(7297):502-6. doi: 10.1038/nature08972. Epub 2010 Apr 28.

PMID:
20428112
26.

Can low-dose abdominal CT replace abdominal plain film in evaluation of acute abdominal pain?

Haller O, Karlsson L, Nyman R.

Ups J Med Sci. 2010 May;115(2):113-20. doi: 10.3109/03009730903294871.

27.

The interferon response circuit in antiviral host defense.

Haller O, Weber F.

Verh K Acad Geneeskd Belg. 2009;71(1-2):73-86. Review.

PMID:
19739399
28.

Protective role of interferon-induced Mx GTPases against influenza viruses.

Haller O, Staeheli P, Kochs G.

Rev Sci Tech. 2009 Apr;28(1):219-31. Review.

29.

Adaptive mutations resulting in enhanced polymerase activity contribute to high virulence of influenza A virus in mice.

Rolling T, Koerner I, Zimmermann P, Holz K, Haller O, Staeheli P, Kochs G.

J Virol. 2009 Jul;83(13):6673-80. doi: 10.1128/JVI.00212-09. Epub 2009 Apr 29.

30.

Intranasal administration of alpha interferon reduces seasonal influenza A virus morbidity in ferrets.

Kugel D, Kochs G, Obojes K, Roth J, Kobinger GP, Kobasa D, Haller O, Staeheli P, von Messling V.

J Virol. 2009 Apr;83(8):3843-51. doi: 10.1128/JVI.02453-08. Epub 2009 Feb 4.

31.

Inhibition of a large double-stranded DNA virus by MxA protein.

Netherton CL, Simpson J, Haller O, Wileman TE, Takamatsu HH, Monaghan P, Taylor G.

J Virol. 2009 Mar;83(5):2310-20. doi: 10.1128/JVI.00781-08. Epub 2008 Dec 24.

32.

Influenza A virus strains differ in sensitivity to the antiviral action of Mx-GTPase.

Dittmann J, Stertz S, Grimm D, Steel J, García-Sastre A, Haller O, Kochs G.

J Virol. 2008 Apr;82(7):3624-31. doi: 10.1128/JVI.01753-07. Epub 2008 Jan 16.

33.
34.

The Mx GTPase family of interferon-induced antiviral proteins.

Haller O, Stertz S, Kochs G.

Microbes Infect. 2007 Nov-Dec;9(14-15):1636-43. Epub 2007 Sep 14. Review.

PMID:
18062906
35.

The antiviral potential of interferon-induced cotton rat Mx proteins against orthomyxovirus (influenza), rhabdovirus, and bunyavirus.

Stertz S, Dittmann J, Blanco JC, Pletneva LM, Haller O, Kochs G.

J Interferon Cytokine Res. 2007 Oct;27(10):847-55.

PMID:
17970694
36.

Pathogenic viruses: smart manipulators of the interferon system.

Haller O, Weber F.

Curr Top Microbiol Immunol. 2007;316:315-34. Review.

PMID:
17969454
37.

Interferon, Mx, and viral countermeasures.

Haller O, Kochs G, Weber F.

Cytokine Growth Factor Rev. 2007 Oct-Dec;18(5-6):425-33. Epub 2007 Aug 1. Review.

PMID:
17683972
38.

The Mx1 gene protects mice against the pandemic 1918 and highly lethal human H5N1 influenza viruses.

Tumpey TM, Szretter KJ, Van Hoeven N, Katz JM, Kochs G, Haller O, García-Sastre A, Staeheli P.

J Virol. 2007 Oct;81(19):10818-21. Epub 2007 Jul 25.

39.

Interferon-induced Mx proteins in antiviral host defense.

Haller O, Staeheli P, Kochs G.

Biochimie. 2007 Jun-Jul;89(6-7):812-8. Epub 2007 May 8. Review.

PMID:
17570575
40.

Induction of MxA gene expression by influenza A virus requires type I or type III interferon signaling.

Holzinger D, Jorns C, Stertz S, Boisson-Dupuis S, Thimme R, Weidmann M, Casanova JL, Haller O, Kochs G.

J Virol. 2007 Jul;81(14):7776-85. Epub 2007 May 9.

41.

Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance gene.

Grimm D, Staeheli P, Hufbauer M, Koerner I, Martínez-Sobrido L, Solórzano A, García-Sastre A, Haller O, Kochs G.

Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6806-11. Epub 2007 Apr 10.

42.

Viral suppression of the interferon system.

Weber F, Haller O.

Biochimie. 2007 Jun-Jul;89(6-7):836-42. Epub 2007 Jan 27. Review.

PMID:
17336442
43.

Interferon-inducible Mx gene expression in cotton rats: cloning, characterization, and expression during influenza viral infection.

Pletneva LM, Haller O, Porter DD, Prince GA, Blanco JC.

J Interferon Cytokine Res. 2006 Dec;26(12):914-21.

PMID:
17238834
44.

Interferon-induced, antiviral human MxA protein localizes to a distinct subcompartment of the smooth endoplasmic reticulum.

Stertz S, Reichelt M, Krijnse-Locker J, Mackenzie J, Simpson JC, Haller O, Kochs G.

J Interferon Cytokine Res. 2006 Sep;26(9):650-60.

PMID:
16978069
45.

Induction of interferon synthesis by the PKR-inhibitory VA RNAs of adenoviruses.

Weber F, Wagner V, Kessler N, Haller O.

J Interferon Cytokine Res. 2006 Jan;26(1):1-7.

PMID:
16426142
46.

Assay and functional analysis of dynamin-like Mx proteins.

Kochs G, Reichelt M, Danino D, Hinshaw JE, Haller O.

Methods Enzymol. 2005;404:632-43.

PMID:
16413306
47.

Type I interferon inhibits Crimean-Congo hemorrhagic fever virus in human target cells.

Andersson I, Lundkvist A, Haller O, Mirazimi A.

J Med Virol. 2006 Feb;78(2):216-22.

PMID:
16372299
48.

The interferon response circuit: induction and suppression by pathogenic viruses.

Haller O, Kochs G, Weber F.

Virology. 2006 Jan 5;344(1):119-30. Review.

49.

Rapid and simple detection of IFN-neutralizing antibodies in chronic hepatitis C non-responsive to IFN-alpha.

Jorns C, Holzinger D, Thimme R, Spangenberg HC, Weidmann M, Rasenack J, Blum HE, Haller O, Kochs G.

J Med Virol. 2006 Jan;78(1):74-82.

PMID:
16299717
50.

Type I interferon-associated recruitment of cytotoxic lymphocytes: a common mechanism in regressive melanocytic lesions.

Wenzel J, Bekisch B, Uerlich M, Haller O, Bieber T, Tüting T.

Am J Clin Pathol. 2005 Jul;124(1):37-48.

PMID:
15923172

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