Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 596

1.

Assessment of glucagon receptor occupancy by Positron Emission Tomography in non-human primates.

Eriksson O, Velikyan I, Haack T, Bossart M, Evers A, Laitinen I, Larsen PJ, Plettenburg O, Takano A, Halldin C, Antoni G, Johansson L, Pierrou S, Wagner M.

Sci Rep. 2019 Oct 18;9(1):14960. doi: 10.1038/s41598-019-51530-0.

PMID:
31628379
2.

The NIOSH B Reader Certification Program-An Update Report (1987-2018) and Future Directions.

Halldin CN, Hale J, Weissman D, Attfield M, Parker JE, Petsonk E, Cohen R, Markle T, Blackley D, Wolfe A, Tallaksen R, Laney AS.

J Occup Environ Med. 2019 Oct 15. doi: 10.1097/JOM.0000000000001735. [Epub ahead of print]

PMID:
31626070
3.

The pro-psychotic metabotropic glutamate receptor compounds fenobam and AZD9272 share binding sites with monoamine oxidase-B inhibitors in humans.

Varnäs K, Cselényi Z, Arakawa R, Nag S, Stepanov V, Moein MM, Johnström P, Kingston L, Elmore CS, Halldin C, Farde L.

Neuropharmacology. 2019 Oct 4:107809. doi: 10.1016/j.neuropharm.2019.107809. [Epub ahead of print]

4.

"In-loop" carbonylation - a simplified method for carbon-11 labeling of drugs and radioligands.

Ferrat M, Dahl K, Halldin C, Schou M.

J Labelled Comp Radiopharm. 2019 Sep 16. doi: 10.1002/jlcr.3805. [Epub ahead of print]

PMID:
31524295
5.

Current Review of Pneumoconiosis Among US Coal Miners.

Hall NB, Blackley DJ, Halldin CN, Laney AS.

Curr Environ Health Rep. 2019 Sep 6. doi: 10.1007/s40572-019-00246-4. [Epub ahead of print] Review.

PMID:
31493280
6.

Identification and Development of an Irreversible Monoacylglycerol Lipase (MAGL) Positron Emission Tomography (PET) Radioligand with High Specificity.

Zhang L, Butler CR, Maresca KP, Takano A, Nag S, Jia Z, Arakawa R, Piro JR, Samad T, Smith DL, Nason DM, O'Neil S, McAllister L, Schildknegt K, Trapa P, McCarthy TJ, Villalobos A, Halldin C.

J Med Chem. 2019 Sep 26;62(18):8532-8543. doi: 10.1021/acs.jmedchem.9b00847. Epub 2019 Sep 16.

PMID:
31483137
7.

Validity and reliability of extrastriatal [11C]raclopride binding quantification in the living human brain.

Svensson JE, Schain M, Plavén-Sigray P, Cervenka S, Tiger M, Nord M, Halldin C, Farde L, Lundberg J.

Neuroimage. 2019 Aug 29;202:116143. doi: 10.1016/j.neuroimage.2019.116143. [Epub ahead of print]

PMID:
31473354
8.

Enhanced Sampling Simulations of Ligand Unbinding Kinetics Controlled by Protein Conformational Changes.

Zhou Y, Zou R, Kuang G, Långström B, Halldin C, Ågren H, Tu Y.

J Chem Inf Model. 2019 Sep 23;59(9):3910-3918. doi: 10.1021/acs.jcim.9b00523. Epub 2019 Sep 10.

PMID:
31454236
9.

Effects of age, BMI and sex on the glial cell marker TSPO - a multicentre [11C]PBR28 HRRT PET study.

Tuisku J, Plavén-Sigray P, Gaiser EC, Airas L, Al-Abdulrasul H, Brück A, Carson RE, Chen MK, Cosgrove KP, Ekblad L, Esterlis I, Farde L, Forsberg A, Halldin C, Helin S, Kosek E, Lekander M, Lindgren N, Marjamäki P, Rissanen E, Sucksdorff M, Varrone A; HRRT [11C ]PBR28 study group, Collste K, Gallezot JD, Hillmer A, Huang Y, Höglund CO, Johansson J, Jucaite A, Lampa J, Nabulsi N, Pittman B, Sandiego CM, Stenkrona P, Rinne J, Matuskey D, Cervenka S.

Eur J Nucl Med Mol Imaging. 2019 Oct;46(11):2329-2338. doi: 10.1007/s00259-019-04403-7. Epub 2019 Jul 30.

10.

Current Review of Pneumoconiosis Among US Coal Miners.

Hall NB, Blackley DJ, Halldin CN, Laney AS.

Curr Environ Health Rep. 2019 Sep;6(3):137-147. doi: 10.1007/s40572-019-00237-5. Review.

PMID:
31302880
11.

Performance Evaluation of a High Resolution Non-Human Primate PET/CT System.

Sarnyai Z, Nagy K, Patay G, Molnár M, Rosenqvist G, Tóth M, Takano A, Gulyás B, Major P, Halldin C, Varrone A.

J Nucl Med. 2019 Jul 13. pii: jnumed.117.206243. doi: 10.2967/jnumed.117.206243. [Epub ahead of print]

PMID:
31302634
12.

Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease.

Zeitler B, Froelich S, Marlen K, Shivak DA, Yu Q, Li D, Pearl JR, Miller JC, Zhang L, Paschon DE, Hinkley SJ, Ankoudinova I, Lam S, Guschin D, Kopan L, Cherone JM, Nguyen HB, Qiao G, Ataei Y, Mendel MC, Amora R, Surosky R, Laganiere J, Vu BJ, Narayanan A, Sedaghat Y, Tillack K, Thiede C, Gärtner A, Kwak S, Bard J, Mrzljak L, Park L, Heikkinen T, Lehtimäki KK, Svedberg MM, Häggkvist J, Tari L, Tóth M, Varrone A, Halldin C, Kudwa AE, Ramboz S, Day M, Kondapalli J, Surmeier DJ, Urnov FD, Gregory PD, Rebar EJ, Muñoz-Sanjuán I, Zhang HS.

Nat Med. 2019 Jul;25(7):1131-1142. doi: 10.1038/s41591-019-0478-3. Epub 2019 Jul 1.

PMID:
31263285
13.

Disease activity in rheumatoid arthritis is inversely related to cerebral TSPO binding assessed by [11C]PBR28 positron emission tomography.

Forsberg A, Lampa J, Estelius J, Cervenka S, Farde L, Halldin C, Lekander M, Olgart Höglund C, Kosek E.

J Neuroimmunol. 2019 Sep 15;334:577000. doi: 10.1016/j.jneuroim.2019.577000. Epub 2019 Jun 22.

14.

Effect of clinically relevant doses of vortioxetine and citalopram on serotonergic PET markers in the nonhuman primate brain.

Yang KC, Stepanov V, Amini N, Martinsson S, Takano A, Bundgaard C, Bang-Andersen B, Sanchez C, Halldin C, Farde L, Finnema SJ.

Neuropsychopharmacology. 2019 Sep;44(10):1706-1713. doi: 10.1038/s41386-019-0442-4. Epub 2019 Jun 19.

PMID:
31216565
15.

Patterns of progressive massive fibrosis on modern coal miner chest radiographs.

Halldin CN, Blackley DJ, Markle T, Cohen RA, Laney AS.

Arch Environ Occup Health. 2019 May 20:1-7. doi: 10.1080/19338244.2019.1593099. [Epub ahead of print]

PMID:
31107177
16.

Synthesis and preclinical evaluation of [18F]FSL25.1188, a reversible PET radioligand for monoamine oxidase-B.

Dahl K, Bernard-Gauthier V, Nag S, Varnäs K, Narayanaswami V, Mahdi Moein M, Arakawa R, Vasdev N, Halldin C.

Bioorg Med Chem Lett. 2019 Jul 1;29(13):1624-1627. doi: 10.1016/j.bmcl.2019.04.040. Epub 2019 Apr 27.

PMID:
31060887
17.

Respirable coal mine dust in underground mines, United States, 1982-2017.

Doney BC, Blackley D, Hale JM, Halldin C, Kurth L, Syamlal G, Laney AS.

Am J Ind Med. 2019 Jun;62(6):478-485. doi: 10.1002/ajim.22974. Epub 2019 Apr 29.

PMID:
31033017
18.

Continued increase in prevalence of r-type opacities among underground coal miners in the USA.

Hall NB, Blackley DJ, Halldin CN, Laney AS.

Occup Environ Med. 2019 Jul;76(7):479-481. doi: 10.1136/oemed-2019-105691. Epub 2019 Apr 25.

PMID:
31023786
19.

A PET study in healthy subjects of brain exposure of 11C-labelled osimertinib - A drug intended for treatment of brain metastases in non-small cell lung cancer.

Varrone A, Varnäs K, Jucaite A, Cselényi Z, Johnström P, Schou M, Vazquez-Romero A, Moein MM, Halldin C, Brown AP, Vishwanathan K, Farde L.

J Cereb Blood Flow Metab. 2019 Apr 20:271678X19843776. doi: 10.1177/0271678X19843776. [Epub ahead of print]

PMID:
31006308
20.

D1-Dopamine Receptor Availability in First-Episode Neuroleptic Naive Psychosis Patients.

Stenkrona P, Matheson GJ, Halldin C, Cervenka S, Farde L.

Int J Neuropsychopharmacol. 2019 Jul 1;22(7):415-425. doi: 10.1093/ijnp/pyz017.

21.

Synthesis and evaluation of two new candidate high-affinity full agonist PET radioligands for imaging 5-HT1B receptors.

Lindberg A, Lu S, Nag S, Schou M, Liow JS, Zoghbi SS, Frankland MP, Gladding RL, Morse CL, Takano A, Amini N, Elmore CS, Lee YS, Innis RB, Halldin C, Pike VW.

Nucl Med Biol. 2019 Mar;70:1-13. doi: 10.1016/j.nucmedbio.2019.01.005. Epub 2019 Jan 26.

22.

Occupational exposure and airflow obstruction and self-reported COPD among ever-employed US adults using a COPD-job exposure matrix.

Doney B, Kurth L, Halldin C, Hale J, Frenk SM.

Am J Ind Med. 2019 May;62(5):393-403. doi: 10.1002/ajim.22958. Epub 2019 Feb 18.

PMID:
30775792
23.

Pulmonary PET imaging confirms preferential lung target occupancy of an inhaled bronchodilator.

Schou M, Ewing P, Cselenyi Z, Fridén M, Takano A, Halldin C, Farde L.

EJNMMI Res. 2019 Jan 29;9(1):9. doi: 10.1186/s13550-019-0479-8.

PMID:
30694407
24.

In vitro phosphodiesterase 10A (PDE10A) binding in whole hemisphere human brain using the PET radioligand [18F]MNI-659.

Svedberg MM, Varnäs K, Varrone A, Mitsios N, Mulder J, Gulyás B, Beaumont V, Munoz-Sanjuan I, Zaleska MM, Schmidt CJ, Halldin C, Mrzljak L.

Brain Res. 2019 May 15;1711:140-145. doi: 10.1016/j.brainres.2019.01.021. Epub 2019 Jan 18.

PMID:
30664847
25.

Venlafaxine ER Blocks the Norepinephrine Transporter in the Brain of Patients with Major Depressive Disorder: a PET Study Using [18F]FMeNER-D2.

Arakawa R, Stenkrona P, Takano A, Svensson J, Andersson M, Nag S, Asami Y, Hirano Y, Halldin C, Lundberg J.

Int J Neuropsychopharmacol. 2019 Apr 1;22(4):278-285. doi: 10.1093/ijnp/pyz003.

26.

PET-MR and SPECT-MR multimodality probes: Development and challenges.

Yang CT, Ghosh KK, Padmanabhan P, Langer O, Liu J, Eng DNC, Halldin C, Gulyás B.

Theranostics. 2018 Nov 29;8(22):6210-6232. doi: 10.7150/thno.26610. eCollection 2018. Review.

27.

The development of a GPR44 targeting radioligand [11C]AZ12204657 for in vivo assessment of beta cell mass.

Jahan M, Johnström P, Selvaraju RK, Svedberg M, Winzell MS, Bernström J, Kingston L, Schou M, Jia Z, Skrtic S, Johansson L, Korsgren O, Farde L, Halldin C, Eriksson O.

EJNMMI Res. 2018 Dec 27;8(1):113. doi: 10.1186/s13550-018-0465-6.

28.

Quantitative Analysis of 18F-PF-06684511, a Novel PET Radioligand for Selective β-Secretase 1 Imaging, in Nonhuman Primate Brain.

Takano A, Chen L, Nag S, Brodney MA, Arakawa R, Chang C, Amini N, Doran SD, Dutra JK, McCarthy TJ, Nolan CE, O'Neill BT, Villalobos A, Zhang L, Halldin C.

J Nucl Med. 2019 Jul;60(7):992-997. doi: 10.2967/jnumed.118.217372. Epub 2018 Dec 7.

PMID:
30530832
29.

Airflow obstruction among ever-employed U.S. adults aged 18-79 years by industry and occupation: NHANES 2007-2008 to 2011-2012.

Kurth L, Doney B, Halldin C, Hale J, Frenk SM.

Am J Ind Med. 2019 Jan;62(1):30-42. doi: 10.1002/ajim.22930. Epub 2018 Dec 5.

30.

Serotonin and Norepinephrine Transporter Occupancy of Tramadol in Nonhuman Primate Using Positron Emission Tomography.

Arakawa R, Takano A, Halldin C.

Int J Neuropsychopharmacol. 2019 Jan 1;22(1):53-56. doi: 10.1093/ijnp/pyy089.

31.

GABAA receptor availability is not altered in adults with autism spectrum disorder or in mouse models.

Horder J, Andersson M, Mendez MA, Singh N, Tangen Ä, Lundberg J, Gee A, Halldin C, Veronese M, Bölte S, Farde L, Sementa T, Cash D, Higgins K, Spain D, Turkheimer F, Mick I, Selvaraj S, Nutt DJ, Lingford-Hughes A, Howes OD, Murphy DG, Borg J.

Sci Transl Med. 2018 Oct 3;10(461). pii: eaam8434. doi: 10.1126/scitranslmed.aam8434.

32.

PET imaging of [11C]PBR28 in Parkinson's disease patients does not indicate increased binding to TSPO despite reduced dopamine transporter binding.

Varnäs K, Cselényi Z, Jucaite A, Halldin C, Svenningsson P, Farde L, Varrone A.

Eur J Nucl Med Mol Imaging. 2019 Feb;46(2):367-375. doi: 10.1007/s00259-018-4161-6. Epub 2018 Oct 1.

33.

Brain glial activation in fibromyalgia - A multi-site positron emission tomography investigation.

Albrecht DS, Forsberg A, Sandström A, Bergan C, Kadetoff D, Protsenko E, Lampa J, Lee YC, Höglund CO, Catana C, Cervenka S, Akeju O, Lekander M, Cohen G, Halldin C, Taylor N, Kim M, Hooker JM, Edwards RR, Napadow V, Kosek E, Loggia ML.

Brain Behav Immun. 2019 Jan;75:72-83. doi: 10.1016/j.bbi.2018.09.018. Epub 2018 Sep 14.

34.

An mGlu4-Positive Allosteric Modulator Alleviates Parkinsonism in Primates.

Charvin D, Di Paolo T, Bezard E, Gregoire L, Takano A, Duvey G, Pioli E, Halldin C, Medori R, Conquet F.

Mov Disord. 2018 Oct;33(10):1619-1631. doi: 10.1002/mds.27462. Epub 2018 Sep 14.

PMID:
30216534
35.

Work Practices and Respiratory Health Status of Appalachian Coal Miners With Progressive Massive Fibrosis.

Reynolds LE, Blackley DJ, Colinet JF, Potts JD, Storey E, Short C, Carson R, Clark KA, Laney AS, Halldin CN.

J Occup Environ Med. 2018 Nov;60(11):e575-e581. doi: 10.1097/JOM.0000000000001443.

36.

Progressive Massive Fibrosis Resurgence Identified in U.S. Coal Miners Filing for Black Lung Benefits, 1970-2016.

Almberg KS, Halldin CN, Blackley DJ, Laney AS, Storey E, Rose CS, Go LHT, Cohen RA.

Ann Am Thorac Soc. 2018 Dec;15(12):1420-1426. doi: 10.1513/AnnalsATS.201804-261OC.

37.

[11C]SCH23390 binding to the D1-dopamine receptor in the human brain-a comparison of manual and automated methods for image analysis.

Stenkrona P, Matheson GJ, Cervenka S, Sigray PP, Halldin C, Farde L.

EJNMMI Res. 2018 Aug 2;8(1):74. doi: 10.1186/s13550-018-0416-2.

38.

Characterization of [11C]PXT012253 as a PET Radioligand for mGlu4 Allosteric Modulators in Nonhuman Primates.

Takano A, Nag S, Jia Z, Jahan M, Forsberg A, Arakawa R, Grybäck P, Duvey G, Halldin C, Charvin D.

Mol Imaging Biol. 2019 Jun;21(3):500-508. doi: 10.1007/s11307-018-1257-0.

PMID:
30066121
39.

Continued Increase in Prevalence of Coal Workers' Pneumoconiosis in the United States, 1970-2017.

Blackley DJ, Halldin CN, Laney AS.

Am J Public Health. 2018 Sep;108(9):1220-1222. doi: 10.2105/AJPH.2018.304517. Epub 2018 Jul 19.

40.

Serotonin concentration enhancers at clinically relevant doses reduce [11C]AZ10419369 binding to the 5-HT1B receptors in the nonhuman primate brain.

Yang KC, Takano A, Halldin C, Farde L, Finnema SJ.

Transl Psychiatry. 2018 Jul 16;8(1):132. doi: 10.1038/s41398-018-0178-7.

41.

Late-Stage Isotopic Carbon Labeling of Pharmaceutically Relevant Cyclic Ureas Directly from CO2.

Del Vecchio A, Caillé F, Chevalier A, Loreau O, Horkka K, Halldin C, Schou M, Camus N, Kessler P, Kuhnast B, Taran F, Audisio D.

Angew Chem Int Ed Engl. 2018 Jul 26;57(31):9744-9748. doi: 10.1002/anie.201804838. Epub 2018 Jul 3.

42.

Dual tracer tau PET imaging reveals different molecular targets for 11C-THK5351 and 11C-PBB3 in the Alzheimer brain.

Chiotis K, Stenkrona P, Almkvist O, Stepanov V, Ferreira D, Arakawa R, Takano A, Westman E, Varrone A, Okamura N, Shimada H, Higuchi M, Halldin C, Nordberg A.

Eur J Nucl Med Mol Imaging. 2018 Jul;45(9):1605-1617. doi: 10.1007/s00259-018-4012-5. Epub 2018 May 12.

43.

Continued increase in lung transplantation for coal workers' pneumoconiosis in the United States.

Blackley DJ, Halldin CN, Laney AS.

Am J Ind Med. 2018 Jul;61(7):621-624. doi: 10.1002/ajim.22856. Epub 2018 May 6.

44.

Interstitial Lung Diseases in the U.S. Mining Industry: Using MSHA Data to Examine Trends and the Prevention Effects of Compliance with Health Regulations, 1996-2015.

Yorio PL, Laney AS, Halldin CN, Blackley DJ, Moore SM, Wizner K, Radonovich LJ, Greenawald LA.

Risk Anal. 2018 Sep;38(9):1962-1971. doi: 10.1111/risa.13000. Epub 2018 Apr 12.

45.

The metabotropic glutamate receptor 5 radioligand [11C]AZD9272 identifies unique binding sites in primate brain.

Varnäs K, Juréus A, Finnema SJ, Johnström P, Raboisson P, Amini N, Takano A, Stepanov V, Halldin C, Farde L.

Neuropharmacology. 2018 Jun;135:455-463. doi: 10.1016/j.neuropharm.2018.03.039. Epub 2018 Mar 30.

46.

Is dopamine D1 receptor availability related to social behavior? A positron emission tomography replication study.

Plavén-Sigray P, Matheson GJ, Gustavsson P, Stenkrona P, Halldin C, Farde L, Cervenka S.

PLoS One. 2018 Mar 15;13(3):e0193770. doi: 10.1371/journal.pone.0193770. eCollection 2018.

47.

A Nonhuman Primate PET Study: Measurement of Brain PDE4 Occupancy by Roflumilast Using (R)-[11C]Rolipram.

Takano A, Uz T, Garcia-Segovia J, Tsai M, Lahu G, Amini N, Nakao R, Jia Z, Halldin C.

Mol Imaging Biol. 2018 Aug;20(4):615-622. doi: 10.1007/s11307-018-1168-0.

PMID:
29441434
48.

Nigrostriatal dopamine transporter availability in early Parkinson's disease.

Fazio P, Svenningsson P, Cselényi Z, Halldin C, Farde L, Varrone A.

Mov Disord. 2018 Apr;33(4):592-599. doi: 10.1002/mds.27316. Epub 2018 Feb 13.

PMID:
29436751
49.

Progressive Massive Fibrosis in Coal Miners From 3 Clinics in Virginia.

Blackley DJ, Reynolds LE, Short C, Carson R, Storey E, Halldin CN, Laney AS.

JAMA. 2018 Feb 6;319(5):500-501. doi: 10.1001/jama.2017.18444. No abstract available.

50.

Identification of a Novel Positron Emission Tomography (PET) Ligand for Imaging β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE-1) in Brain.

Zhang L, Chen L, Dutra JK, Beck EM, Nag S, Takano A, Amini N, Arakawa R, Brodney MA, Buzon LM, Doran SD, Lanyon LF, McCarthy TJ, Bales KR, Nolan CE, O'Neill BT, Schildknegt K, Halldin C, Villalobos A.

J Med Chem. 2018 Apr 26;61(8):3296-3308. doi: 10.1021/acs.jmedchem.7b01769. Epub 2018 Feb 2.

PMID:
29356535

Supplemental Content

Loading ...
Support Center