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Clinical validity and intrarater and test-retest reliability of the Structured Clinical Interview for DSM-5 Disorders-Clinician Version (SCID-5-CV).

de Lima Osório F, Loureiro SR, Hallak JEC, Machado-de-Sousa JP, Ushirohira JM, Baes CVV, Apolinário TD, Donadon MF, Bolsoni L, Guimarães T, Fracon VS, Casagrande AP, Pizzeta F, Mascarenhas R, Sanches RF, Santos RG, Martin-Santos RL, Crippa JAS.

Psychiatry Clin Neurosci. 2019 Sep 6. doi: 10.1111/pcn.12931. [Epub ahead of print]


Application of corneal injury models in dual fluorescent reporter transgenic mice to understand the roles of the cornea and limbus in angiogenic and lymphangiogenic privilege.

Gao X, Guo K, Santosa SM, Montana M, Yamakawa M, Hallak JA, Han KY, Doh SJ, Rosenblatt MI, Chang JH, Azar DT.

Sci Rep. 2019 Aug 23;9(1):12331. doi: 10.1038/s41598-019-48811-z.


Biological bases for a possible effect of cannabidiol in Parkinson's disease.

Ferreira-Junior NC, Campos AC, Guimarães FS, Del-Bel E, Zimmermann PMDR, Brum Junior L, Hallak JE, Crippa JA, Zuardi AW.

Braz J Psychiatry. 2019 Jul 15. pii: S1516-44462019005012104. doi: 10.1590/1516-4446-2019-0460. [Epub ahead of print]


Zone of retinal vascularization and refractive error in premature eyes with and without spontaneously regressed retinopathy of prematurity.

Dikopf MS, Machen LA, Hallak JA, Chau FY, Kassem IS.

J AAPOS. 2019 Jun 20. pii: S1091-8531(19)30140-5. doi: 10.1016/j.jaapos.2019.03.006. [Epub ahead of print]


Ayahuasca, an ancient substance with traditional and contemporary use in neuropsychiatry and neuroscience.

Dos Santos RG, Hallak JEC.

Epilepsy Behav. 2019 Jun 7. pii: S1525-5050(19)30251-3. doi: 10.1016/j.yebeh.2019.04.053. [Epub ahead of print] Review.


Personality Inventory for DSM-5 (PID-5): cross-cultural adaptation and content validity in the Brazilian context.

Barchi-Ferreira AM, Loureiro SR, Torres AR, da Silva TDA, Moreno AL, DeSousa DA, Chagas MHN, Dos Santos RG, Machado-de-Souza JP, Chagas NMS, Hallak JEC, Crippa JAS, Osório FL.

Trends Psychiatry Psychother. 2019 May 30. pii: S2237-60892019005004105. doi: 10.1590/2237-6089-2018-0098. [Epub ahead of print]


An association between large optic nerve cupping and cognitive function.

Vajaranant TS, Hallak J, Espeland MA, Pasquale LR, Klein BE, Meuer SM, Rapp SR, Haan MN, Maki PM.

Am J Ophthalmol. 2019 Jun 1. pii: S0002-9394(19)30251-X. doi: 10.1016/j.ajo.2019.05.019. [Epub ahead of print]


Effects of Parkinson's disease on molar bite force, electromyographic activity and muscle thickness of the masseter, temporal and sternocleidomastoid muscles: A case-control study.

Donizetti Verri E, da Silva GP, Marianetti Fioco E, Soares da Silva N, Valin Fabrin SC, Augusto Bueno Zanella C, Roberta Garrefa C, Faria Júnior M, Siéssere S, Hallak JEC, Palinkas M, Chaves TC, Regalo SCH.

J Oral Rehabil. 2019 Oct;46(10):912-919. doi: 10.1111/joor.12824. Epub 2019 Jun 17.


Role of the endocannabinoid and endovanilloid systems in an animal model of schizophrenia-related emotional processing/cognitive deficit.

Almeida V, Levin R, Peres FF, Suiama MA, Vendramini AM, Santos CM, Silva ND, Zuardi AW, Hallak JEC, Crippa JA, Abílio VC.

Neuropharmacology. 2019 Sep 1;155:44-53. doi: 10.1016/j.neuropharm.2019.05.015. Epub 2019 May 16.


Serotonergic hallucinogens and recognition of facial emotion expressions: a systematic review of the literature.

Rocha JM, Osório FL, Crippa JAS, Bouso JC, Rossi GN, Hallak JEC, Dos Santos RG.

Ther Adv Psychopharmacol. 2019 Apr 26;9:2045125319845774. doi: 10.1177/2045125319845774. eCollection 2019. Review.


Imaging, Genetic, and Demographic Factors Associated With Conversion to Neovascular Age-Related Macular Degeneration: Secondary Analysis of a Randomized Clinical Trial.

Hallak JA, de Sisternes L, Osborne A, Yaspan B, Rubin DL, Leng T.

JAMA Ophthalmol. 2019 Jul 1;137(7):738-744. doi: 10.1001/jamaophthalmol.2019.0868.


Impact of Parkinson's disease on the efficiency of masticatory cycles: Electromyographic analysis.

da Silva N, Verri E, Palinkas M, Hallak J, Regalo S, Siéssere S.

Med Oral Patol Oral Cir Bucal. 2019 May 1;24(3):e314-e318. doi: 10.4317/medoral.22841.


Cannabidiol attenuates mechanical allodynia in streptozotocin-induced diabetic rats via serotonergic system activation through 5-HT1A receptors.

Jesus CHA, Redivo DDB, Gasparin AT, Sotomaior BB, de Carvalho MC, Genaro K, Zuardi AW, Hallak JEC, Crippa JA, Zanoveli JM, da Cunha JM.

Brain Res. 2019 Jul 15;1715:156-164. doi: 10.1016/j.brainres.2019.03.014. Epub 2019 Mar 18.


Primary Health Care Center (PHCC) Location-Allocation with Multi-Objective Modelling: A Case Study in Idleb, Syria.

Miç P, Koyuncu M, Hallak J.

Int J Environ Res Public Health. 2019 Mar 6;16(5). pii: E811. doi: 10.3390/ijerph16050811.


Spinocerebellar ataxia: Functional analysis of the stomatognathic system.

Ferreira B, Palinkas M, Gonçalves L, da Silva G, Arnoni V, Regalo I, Vasconcelos P, Júnior WM, Hallak J, Regalo S, Siéssere S.

Med Oral Patol Oral Cir Bucal. 2019 Mar 1;24(2):e165-e171. doi: 10.4317/medoral.22839.


Ayahuasca and Public Health: Health Status, Psychosocial Well-Being, Lifestyle, and Coping Strategies in a Large Sample of Ritual Ayahuasca Users.

Ona G, Kohek M, Massaguer T, Gomariz A, Jiménez DF, Dos Santos RG, Hallak JEC, Alcázar-Córcoles MÁ, Bouso JC.

J Psychoactive Drugs. 2019 Apr-Jun;51(2):135-145. doi: 10.1080/02791072.2019.1567961. Epub 2019 Feb 7.


Is cannabidiol the ideal drug to treat non-motor Parkinson's disease symptoms?

Crippa JAS, Hallak JEC, Zuardi AW, Guimarães FS, Tumas V, Dos Santos RG.

Eur Arch Psychiatry Clin Neurosci. 2019 Feb;269(1):121-133. doi: 10.1007/s00406-019-00982-6. Epub 2019 Jan 31. Review.


The Influence of Depression on the Psychometric Properties of the Maslach Burnout Inventory-Human Services Survey: A Cross-Sectional Study With Nursing Assistants.

Trigo TR, de Freitas CCS, Wang YP, Ribeiro FG, de Lucia MCS, Siqueira JO, Iosifescu DV, Hallak JEC, Fraguas R.

Front Psychiatry. 2018 Dec 18;9:695. doi: 10.3389/fpsyt.2018.00695. eCollection 2018.


Direct and Indirect Flap Measurements in Femtosecond Laser-Assisted In Situ Keratomileusis.

Crispim J, Allemann N, Hallak JA, Azar DT, De La Cruz J.

Cornea. 2019 Mar;38(3):297-303. doi: 10.1097/ICO.0000000000001836.


Cannabidiol reduces airway inflammation and fibrosis in experimental allergic asthma.

Vuolo F, Abreu SC, Michels M, Xisto DG, Blanco NG, Hallak JE, Zuardi AW, Crippa JA, Reis C, Bahl M, Pizzichinni E, Maurici R, Pizzichinni MMM, Rocco PRM, Dal-Pizzol F.

Eur J Pharmacol. 2019 Jan 15;843:251-259. doi: 10.1016/j.ejphar.2018.11.029. Epub 2018 Nov 24.


Acute effects of ayahuasca in a juvenile non-human primate model of depression.

da Silva FS, Silva EAS, Sousa GM Jr, Maia-de-Oliveira JP, Soares-Rachetti VP, de Araujo DB, Sousa MBC, Lobão-Soares B, Hallak J, Galvão-Coelho NL.

Braz J Psychiatry. 2019 Jul-Aug;41(4):280-288. doi: 10.1590/1516-4446-2018-0140. Epub 2018 Nov 8.


Possible Interactions Between 5-HT2A Receptors and the Endocannabinoid System in Humans: Preliminary Evidence of Interactive Effects of Ayahuasca and Endocannabinoids in a Healthy Human Subject.

Dos Santos RG, Crippa JA, Osório FL, Rocha JM, Rossi GN, Marchioni C, Queiroz MEC, Silveira GO, Yonamine M, Hallak JEC.

J Clin Psychopharmacol. 2018 Dec;38(6):644-646. doi: 10.1097/JCP.0000000000000973. No abstract available.


Cannabidiol Administered During Peri-Adolescence Prevents Behavioral Abnormalities in an Animal Model of Schizophrenia.

Peres FF, Diana MC, Levin R, Suiama MA, Almeida V, Vendramini AM, Santos CM, Zuardi AW, Hallak JEC, Crippa JA, Abílio VC.

Front Pharmacol. 2018 Aug 21;9:901. doi: 10.3389/fphar.2018.00901. eCollection 2018.


Antiapoptotic effects of cannabidiol in an experimental model of cognitive decline induced by brain iron overload.

da Silva VK, de Freitas BS, Garcia RCL, Monteiro RT, Hallak JE, Zuardi AW, Crippa JAS, Schröder N.

Transl Psychiatry. 2018 Sep 3;8(1):176. doi: 10.1038/s41398-018-0232-5.


Cannabinoid-Based Therapies and Brain Development: Potential Harmful Effect of Early Modulation of the Endocannabinoid System.

Schonhofen P, Bristot IJ, Crippa JA, Hallak JEC, Zuardi AW, Parsons RB, Klamt F.

CNS Drugs. 2018 Aug;32(8):697-712. doi: 10.1007/s40263-018-0550-4.


Efficacy, tolerability, and safety of serotonergic psychedelics for the management of mood, anxiety, and substance-use disorders: a systematic review of systematic reviews.

Dos Santos RG, Bouso JC, Alcázar-Córcoles MÁ, Hallak JEC.

Expert Rev Clin Pharmacol. 2018 Sep;11(9):889-902. doi: 10.1080/17512433.2018.1511424. Epub 2018 Aug 23. Review.


Rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression: a randomized placebo-controlled trial.

Palhano-Fontes F, Barreto D, Onias H, Andrade KC, Novaes MM, Pessoa JA, Mota-Rolim SA, Osório FL, Sanches R, Dos Santos RG, Tófoli LF, de Oliveira Silveira G, Yonamine M, Riba J, Santos FR, Silva-Junior AA, Alchieri JC, Galvão-Coelho NL, Lobão-Soares B, Hallak JEC, Arcoverde E, Maia-de-Oliveira JP, Araújo DB.

Psychol Med. 2019 Mar;49(4):655-663. doi: 10.1017/S0033291718001356. Epub 2018 Jun 15.


Cannabidiol did not induce teratogenicity or neurotoxicity in exposed zebrafish embryos.

Valim Brigante TA, Abe FR, Zuardi AW, Hallak JEC, Crippa JAS, de Oliveira DP.

Chem Biol Interact. 2018 Aug 1;291:81-86. doi: 10.1016/j.cbi.2018.06.008. Epub 2018 Jun 11.


Alterations in the stomatognathic system due to amyotrophic lateral sclerosis.

Gonçalves LMN, Palinkas M, Hallak JEC, Marques Júnior W, Vasconcelos PB, Frota NPR, Regalo IH, Siéssere S, Regalo SCH.

J Appl Oral Sci. 2018 Jun 11;26:e20170408. doi: 10.1590/1678-7757-2017-0408.


Cannabidiol as a Promising Strategy to Treat and Prevent Movement Disorders?

Peres FF, Lima AC, Hallak JEC, Crippa JA, Silva RH, Abílio VC.

Front Pharmacol. 2018 May 11;9:482. doi: 10.3389/fphar.2018.00482. eCollection 2018. Review.


Psychedelics and Personality.

Aixalà M, Dos Santos RG, Hallak JEC, Bouso JC.

ACS Chem Neurosci. 2018 Oct 17;9(10):2304-2306. doi: 10.1021/acschemneuro.8b00237. Epub 2018 Jun 4.


An Overview of Animal Models Related to Schizophrenia.

Winship IR, Dursun SM, Baker GB, Balista PA, Kandratavicius L, Maia-de-Oliveira JP, Hallak J, Howland JG.

Can J Psychiatry. 2019 Jan;64(1):5-17. doi: 10.1177/0706743718773728. Epub 2018 May 9.


No Acute Effects of Cannabidiol on the Sleep-Wake Cycle of Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study.

Linares IMP, Guimaraes FS, Eckeli A, Crippa ACS, Zuardi AW, Souza JDS, Hallak JE, Crippa JAS.

Front Pharmacol. 2018 Apr 5;9:315. doi: 10.3389/fphar.2018.00315. eCollection 2018.


Sodium nitroprusside is effective in preventing and/or reversing the development of schizophrenia-related behaviors in an animal model: The SHR strain.

Diana MC, Peres FF, Justi V, Bressan RA, Lacerda ALT, Crippa JA, Hallak JEC, Abilio VC.

CNS Neurosci Ther. 2018 Jul;24(7):624-632. doi: 10.1111/cns.12852. Epub 2018 Apr 14.


Maternal administration of cannabidiol promotes an anti-inflammatory effect on the intestinal wall in a gastroschisis rat model.

Callejas GH, Figueira RL, Gonçalves FLL, Volpe FAP, Zuardi AW, Crippa JA, Hallak JE, Sbragia L.

Braz J Med Biol Res. 2018 Mar 15;51(5):e7132. doi: 10.1590/1414-431X20177132.


Male Sexual Quality Of Life Is Maintained Satisfactorily Throughout Life In The Amazon Rainforest.

Teixeira T, Nazima M, Hallak J.

Sex Med. 2018 Jun;6(2):90-96. doi: 10.1016/j.esxm.2017.11.002. Epub 2018 Mar 6.


Author Correction: Well-being, problematic alcohol consumption and acute subjective drug effects in past-year ayahuasca users: a large, international, self-selecting online survey.

Lawn W, Hallak JE, Crippa JA, Dos Santos R, Porffy L, Barratt MJ, Ferris JA, Winstock AR, Morgan CJA.

Sci Rep. 2018 Mar 1;8(1):4059. doi: 10.1038/s41598-018-21666-6.


Serotonergic psychedelics and personality: A systematic review of contemporary research.

Bouso JC, Dos Santos RG, Alcázar-Córcoles MÁ, Hallak JEC.

Neurosci Biobehav Rev. 2018 Apr;87:118-132. doi: 10.1016/j.neubiorev.2018.02.004. Epub 2018 Feb 13.


Five year outcomes of Boston type I keratoprosthesis as primary versus secondary penetrating corneal procedure in a matched case control study.

Kang KB, Karas FI, Rai R, Hallak JA, Kang JJ, de la Cruz J, Cortina MS.

PLoS One. 2018 Feb 6;13(2):e0192381. doi: 10.1371/journal.pone.0192381. eCollection 2018.


Novel insights into mitochondrial molecular targets of iron-induced neurodegeneration: Reversal by cannabidiol.

da Silva VK, de Freitas BS, Dornelles VC, Kist LW, Bogo MR, Silva MC, Streck EL, Hallak JE, Zuardi AW, Crippa JAS, Schröder N.

Brain Res Bull. 2018 May;139:1-8. doi: 10.1016/j.brainresbull.2018.01.014. Epub 2018 Jan 31.


Ayahuasca: Psychological and Physiologic Effects, Pharmacology and Potential Uses in Addiction and Mental Illness.

Hamill J, Hallak J, Dursun SM, Baker G.

Curr Neuropharmacol. 2019;17(2):108-128. doi: 10.2174/1570159X16666180125095902. Review.


Lipopolysaccharide and lipotheicoic acid differentially modulate epididymal cytokine and chemokine profiles and sperm parameters in experimental acute epididymitis.

Silva EJR, Ribeiro CM, Mirim AFM, Silva AAS, Romano RM, Hallak J, Avellar MCW.

Sci Rep. 2018 Jan 8;8(1):103. doi: 10.1038/s41598-017-17944-4.


Brain functional and perfusional alterations in schizophrenia: an arterial spin labeling study.

Oliveira ÍAF, Guimarães TM, Souza RM, Dos Santos AC, Machado-de-Sousa JP, Hallak JEC, Leoni RF.

Psychiatry Res Neuroimaging. 2018 Feb 28;272:71-78. doi: 10.1016/j.pscychresns.2017.12.001. Epub 2017 Dec 5.


Retroprosthetic Membrane Formation in Boston Keratoprosthesis: A Case-Control-Matched Comparison of Titanium Versus PMMA Backplate.

Talati RK, Hallak JA, Karas FI, de la Cruz J, Cortina MS.

Cornea. 2018 Feb;37(2):145-150. doi: 10.1097/ICO.0000000000001462.


Well-being, problematic alcohol consumption and acute subjective drug effects in past-year ayahuasca users: a large, international, self-selecting online survey.

Lawn W, Hallak JE, Crippa JA, Dos Santos R, Porffy L, Barratt MJ, Ferris JA, Winstock AR, Morgan CJA.

Sci Rep. 2017 Nov 9;7(1):15201. doi: 10.1038/s41598-017-14700-6. Erratum in: Sci Rep. 2018 Mar 1;8(1):4059.


Cannabinoids and Vanilloids in Schizophrenia: Neurophysiological Evidence and Directions for Basic Research.

Ruggiero RN, Rossignoli MT, De Ross JB, Hallak JEC, Leite JP, Bueno-Junior LS.

Front Pharmacol. 2017 Jun 21;8:399. doi: 10.3389/fphar.2017.00399. eCollection 2017. Review.


Ayahuasca intoxication.

Dos Santos RG, Bouso JC, Hallak JEC.

Med Clin (Barc). 2017 Nov 22;149(10):461-462. doi: 10.1016/j.medcli.2017.04.032. Epub 2017 Jun 15. English, Spanish. No abstract available.


Inverted U-Shaped Dose-Response Curve of the Anxiolytic Effect of Cannabidiol during Public Speaking in Real Life.

Zuardi AW, Rodrigues NP, Silva AL, Bernardo SA, Hallak JEC, Guimarães FS, Crippa JAS.

Front Pharmacol. 2017 May 11;8:259. doi: 10.3389/fphar.2017.00259. eCollection 2017.

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