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Items: 22

1.

Changes in osteoblast, chondrocyte, and adipocyte lineages mediate the bone anabolic actions of PTH and small molecule GSK-3 inhibitor.

Kulkarni NH, Wei T, Kumar A, Dow ER, Stewart TR, Shou J, N'cho M, Sterchi DL, Gitter BD, Higgs RE, Halladay DL, Engler TA, Martin TJ, Bryant HU, Ma YL, Onyia JE.

J Cell Biochem. 2007 Dec 15;102(6):1504-18.

PMID:
17520664
2.

A proteomic analysis of adult rat bone reveals the presence of cartilage/chondrocyte markers.

Schreiweis MA, Butler JP, Kulkarni NH, Knierman MD, Higgs RE, Halladay DL, Onyia JE, Hale JE.

J Cell Biochem. 2007 May 15;101(2):466-76.

PMID:
17205546
3.

Orally bioavailable GSK-3alpha/beta dual inhibitor increases markers of cellular differentiation in vitro and bone mass in vivo.

Kulkarni NH, Onyia JE, Zeng Q, Tian X, Liu M, Halladay DL, Frolik CA, Engler T, Wei T, Kriauciunas A, Martin TJ, Sato M, Bryant HU, Ma YL.

J Bone Miner Res. 2006 Jun;21(6):910-20.

4.

Expression profiling of rat femur revealed suppression of bone formation genes by treatment with alendronate and estrogen but not raloxifene.

Helvering LM, Liu R, Kulkarni NH, Wei T, Chen P, Huang S, Lawrence F, Halladay DL, Miles RR, Ambrose EM, Sato M, Ma YL, Frolik CA, Dow ER, Bryant HU, Onyia JE.

Mol Pharmacol. 2005 Nov;68(5):1225-38. Epub 2005 Aug 3.

PMID:
16079270
5.

Effects of parathyroid hormone on Wnt signaling pathway in bone.

Kulkarni NH, Halladay DL, Miles RR, Gilbert LM, Frolik CA, Galvin RJ, Martin TJ, Gillespie MT, Onyia JE.

J Cell Biochem. 2005 Aug 15;95(6):1178-90.

PMID:
15962290
6.

High-content screening assay for activators of the Wnt/Fzd pathway in primary human cells.

Borchert KM, Galvin RJ, Frolik CA, Hale LV, Halladay DL, Gonyier RJ, Trask OJ, Nickischer DR, Houck KA.

Assay Drug Dev Technol. 2005 Apr;3(2):133-41.

PMID:
15871688
7.

Molecular profile of catabolic versus anabolic treatment regimens of parathyroid hormone (PTH) in rat bone: an analysis by DNA microarray.

Onyia JE, Helvering LM, Gelbert L, Wei T, Huang S, Chen P, Dow ER, Maran A, Zhang M, Lotinun S, Lin X, Halladay DL, Miles RR, Kulkarni NH, Ambrose EM, Ma YL, Frolik CA, Sato M, Bryant HU, Turner RT.

J Cell Biochem. 2005 May 15;95(2):403-18.

PMID:
15779007
8.

Differential effects of estrogen and raloxifene on messenger RNA and matrix metalloproteinase 2 activity in the rat uterus.

Helvering LM, Adrian MD, Geiser AG, Estrem ST, Wei T, Huang S, Chen P, Dow ER, Calley JN, Dodge JA, Grese TA, Jones SA, Halladay DL, Miles RR, Onyia JE, Ma YL, Sato M, Bryant HU.

Biol Reprod. 2005 Apr;72(4):830-41. Epub 2004 Dec 1.

PMID:
15576828
9.

Novel and selective small molecule stimulators of osteoprotegerin expression inhibit bone resorption.

Onyia JE, Galvin RJ, Ma YL, Halladay DL, Miles RR, Yang X, Fuson T, Cain RL, Zeng QQ, Chandrasekhar S, Emkey R, Xu Y, Thirunavukkarasu K, Bryant HU, Martin TJ.

J Pharmacol Exp Ther. 2004 Apr;309(1):369-79. Epub 2004 Jan 12.

PMID:
14718597
10.

Analysis of regulator of G-protein signaling-2 (RGS-2) expression and function in osteoblastic cells.

Thirunavukkarasu K, Halladay DL, Miles RR, Geringer CD, Onyia JE.

J Cell Biochem. 2002;85(4):837-50.

PMID:
11968023
11.

Parathyroid hormone (hPTH 1-38) stimulates the expression of UBP41, an ubiquitin-specific protease, in bone.

Miles RR, Sluka JP, Halladay DL, Santerre RF, Hale LV, Bloem L, Patanjali SR, Galvin RJ, Ma L, Hock JM, Onyia JE.

J Cell Biochem. 2002;85(2):229-42.

PMID:
11948679
12.

Identification of signal transduction pathways and promoter sequences that mediate parathyroid hormone 1-38 inhibition of osteoprotegerin gene expression.

Halladay DL, Miles RR, Thirunavukkarasu K, Chandrasekhar S, Martin TJ, Onyia JE.

J Cell Biochem. 2001;84(1):1-11.

PMID:
11746511
13.

Catabolic effects of continuous human PTH (1--38) in vivo is associated with sustained stimulation of RANKL and inhibition of osteoprotegerin and gene-associated bone formation.

Ma YL, Cain RL, Halladay DL, Yang X, Zeng Q, Miles RR, Chandrasekhar S, Martin TJ, Onyia JE.

Endocrinology. 2001 Sep;142(9):4047-54.

PMID:
11517184
14.

Stimulation of osteoprotegerin (OPG) gene expression by transforming growth factor-beta (TGF-beta). Mapping of the OPG promoter region that mediates TGF-beta effects.

Thirunavukkarasu K, Miles RR, Halladay DL, Yang X, Galvin RJ, Chandrasekhar S, Martin TJ, Onyia JE.

J Biol Chem. 2001 Sep 28;276(39):36241-50. Epub 2001 Jul 12.

15.

ADAMTS-1: A cellular disintegrin and metalloprotease with thrombospondin motifs is a target for parathyroid hormone in bone.

Miles RR, Sluka JP, Halladay DL, Santerre RF, Hale LV, Bloem L, Thirunavukkarasu K, Galvin RJ, Hock JM, Onyia JE.

Endocrinology. 2000 Dec;141(12):4533-42.

PMID:
11108265
16.

The osteoblast-specific transcription factor Cbfa1 contributes to the expression of osteoprotegerin, a potent inhibitor of osteoclast differentiation and function.

Thirunavukkarasu K, Halladay DL, Miles RR, Yang X, Galvin RJ, Chandrasekhar S, Martin TJ, Onyia JE.

J Biol Chem. 2000 Aug 18;275(33):25163-72.

17.

In vivo demonstration that human parathyroid hormone 1-38 inhibits the expression of osteoprotegerin in bone with the kinetics of an immediate early gene.

Onyia JE, Miles RR, Yang X, Halladay DL, Hale J, Glasebrook A, McClure D, Seno G, Churgay L, Chandrasekhar S, Martin TJ.

J Bone Miner Res. 2000 May;15(5):863-71.

18.

Cryptic enhancer elements in luciferase reporter vectors respond to the osteoblast-specific transcription factor Osf2/Cbfa1.

Thirunavukkarasu K, Miles RR, Halladay DL, Onyia JE.

Biotechniques. 2000 Mar;28(3):506-10.

19.

The human transaldolase gene (TALDO1) is located on chromosome 11 at p15.4-p15.5.

Banki K, Eddy RL, Shows TB, Halladay DL, Bullrich F, Croce CM, Jurecic V, Baldini A, Perl A.

Genomics. 1997 Oct 1;45(1):233-8.

PMID:
9339383
20.

One of three CCArGG box/serum response elements of the beta-actin gene is an insulin-responsive element.

Onyia JE, Halladay DL, Messina JL.

Endocrinology. 1995 Jan;136(1):306-15.

PMID:
7828546
21.

Identification of beta-actin sequences necessary for induction by phorbol esters and calcium ionophores.

Onyia JE, Halladay DL, Messina JL.

Oncogene. 1994 Jun;9(6):1713-22.

PMID:
8183567

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