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Items: 41

1.

Serological analysis of Ebola virus survivors and close contacts in Sierra Leone: A cross-sectional study.

Halfmann PJ, Eisfeld AJ, Watanabe T, Maemura T, Yamashita M, Fukuyama S, Armbrust T, Rozich I, N'jai A, Neumann G, Kawaoka Y, Sahr F.

PLoS Negl Trop Dis. 2019 Aug 1;13(8):e0007654. doi: 10.1371/journal.pntd.0007654. eCollection 2019 Aug.

2.

Isolation of Highly Pathogenic H5N1 Influenza Viruses in 2009-2013 in Vietnam.

Zhong G, Fan S, Lopes TJS, Le MQ, van Bakel H, Dutta J, Smith GJD, Jayakumar J, Nguyen HLK, Hoang PVM, Halfmann P, Hatta M, Su YCF, Neumann G, Kawaoka Y.

Front Microbiol. 2019 Jun 25;10:1411. doi: 10.3389/fmicb.2019.01411. eCollection 2019.

3.

Longitudinal Analysis of the Human B Cell Response to Ebola Virus Infection.

Davis CW, Jackson KJL, McElroy AK, Halfmann P, Huang J, Chennareddy C, Piper AE, Leung Y, Albariño CG, Crozier I, Ellebedy AH, Sidney J, Sette A, Yu T, Nielsen SCA, Goff AJ, Spiropoulou CF, Saphire EO, Cavet G, Kawaoka Y, Mehta AK, Glass PJ, Boyd SD, Ahmed R.

Cell. 2019 May 30;177(6):1566-1582.e17. doi: 10.1016/j.cell.2019.04.036. Epub 2019 May 16.

PMID:
31104840
4.

Plasma lipidome reveals critical illness and recovery from human Ebola virus disease.

Kyle JE, Burnum-Johnson KE, Wendler JP, Eisfeld AJ, Halfmann PJ, Watanabe T, Sahr F, Smith RD, Kawaoka Y, Waters KM, Metz TO.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3919-3928. doi: 10.1073/pnas.1815356116. Epub 2019 Feb 11.

5.

Early Human B Cell Response to Ebola Virus in Four U.S. Survivors of Infection.

Williamson LE, Flyak AI, Kose N, Bombardi R, Branchizio A, Reddy S, Davidson E, Doranz BJ, Fusco ML, Saphire EO, Halfmann PJ, Kawaoka Y, Piper AE, Glass PJ, Crowe JE Jr.

J Virol. 2019 Apr 3;93(8). pii: e01439-18. doi: 10.1128/JVI.01439-18. Print 2019 Apr 15.

6.

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection.

Saphire EO, Schendel SL, Fusco ML, Gangavarapu K, Gunn BM, Wec AZ, Halfmann PJ, Brannan JM, Herbert AS, Qiu X, Wagh K, He S, Giorgi EE, Theiler J, Pommert KBJ, Krause TB, Turner HL, Murin CD, Pallesen J, Davidson E, Ahmed R, Aman MJ, Bukreyev A, Burton DR, Crowe JE Jr, Davis CW, Georgiou G, Krammer F, Kyratsous CA, Lai JR, Nykiforuk C, Pauly MH, Rijal P, Takada A, Townsend AR, Volchkov V, Walker LM, Wang CI, Zeitlin L, Doranz BJ, Ward AB, Korber B, Kobinger GP, Andersen KG, Kawaoka Y, Alter G, Chandran K, Dye JM; Viral Hemorrhagic Fever Immunotherapeutic Consortium.

Cell. 2018 Aug 9;174(4):938-952.e13. doi: 10.1016/j.cell.2018.07.033.

7.

A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus.

Gunn BM, Yu WH, Karim MM, Brannan JM, Herbert AS, Wec AZ, Halfmann PJ, Fusco ML, Schendel SL, Gangavarapu K, Krause T, Qiu X, He S, Das J, Suscovich TJ, Lai J, Chandran K, Zeitlin L, Crowe JE Jr, Lauffenburger D, Kawaoka Y, Kobinger GP, Andersen KG, Dye JM, Saphire EO, Alter G.

Cell Host Microbe. 2018 Aug 8;24(2):221-233.e5. doi: 10.1016/j.chom.2018.07.009.

8.

The Induction of IL-1β Secretion Through the NLRP3 Inflammasome During Ebola Virus Infection.

Halfmann P, Hill-Batorski L, Kawaoka Y.

J Infect Dis. 2018 Nov 22;218(suppl_5):S504-S507. doi: 10.1093/infdis/jiy433.

PMID:
30060221
9.

Mutations in the PA Protein of Avian H5N1 Influenza Viruses Affect Polymerase Activity and Mouse Virulence.

Zhong G, Le MQ, Lopes TJS, Halfmann P, Hatta M, Fan S, Neumann G, Kawaoka Y.

J Virol. 2018 Jan 30;92(4). pii: e01557-17. doi: 10.1128/JVI.01557-17. Print 2018 Feb 15.

10.

Multi-platform 'Omics Analysis of Human Ebola Virus Disease Pathogenesis.

Eisfeld AJ, Halfmann PJ, Wendler JP, Kyle JE, Burnum-Johnson KE, Peralta Z, Maemura T, Walters KB, Watanabe T, Fukuyama S, Yamashita M, Jacobs JM, Kim YM, Casey CP, Stratton KG, Webb-Robertson BM, Gritsenko MA, Monroe ME, Weitz KK, Shukla AK, Tian M, Neumann G, Reed JL, van Bakel H, Metz TO, Smith RD, Waters KM, N'jai A, Sahr F, Kawaoka Y.

Cell Host Microbe. 2017 Dec 13;22(6):817-829.e8. doi: 10.1016/j.chom.2017.10.011. Epub 2017 Nov 16.

11.

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling.

Burnum-Johnson KE, Kyle JE, Eisfeld AJ, Casey CP, Stratton KG, Gonzalez JF, Habyarimana F, Negretti NM, Sims AC, Chauhan S, Thackray LB, Halfmann PJ, Walters KB, Kim YM, Zink EM, Nicora CD, Weitz KK, Webb-Robertson BM, Nakayasu ES, Ahmer B, Konkel ME, Motin V, Baric RS, Diamond MS, Kawaoka Y, Waters KM, Smith RD, Metz TO.

Analyst. 2017 Jan 26;142(3):442-448. doi: 10.1039/c6an02486f.

12.

Ebola Virus Stability Under Hospital and Environmental Conditions.

Westhoff Smith D, Hill-Batorski L, N'jai A, Eisfeld AJ, Neumann G, Halfmann P, Kawaoka Y.

J Infect Dis. 2016 Oct 15;214(suppl 3):S142-S144. Epub 2016 Jun 7.

PMID:
27279525
13.

The Synthetic Antiviral Drug Arbidol Inhibits Globally Prevalent Pathogenic Viruses.

Pécheur EI, Borisevich V, Halfmann P, Morrey JD, Smee DF, Prichard M, Mire CE, Kawaoka Y, Geisbert TW, Polyak SJ.

J Virol. 2016 Jan 6;90(6):3086-92. doi: 10.1128/JVI.02077-15.

14.

Crystal Structure of Marburg Virus VP40 Reveals a Broad, Basic Patch for Matrix Assembly and a Requirement of the N-Terminal Domain for Immunosuppression.

Oda S, Noda T, Wijesinghe KJ, Halfmann P, Bornholdt ZA, Abelson DM, Armbrust T, Stahelin RV, Kawaoka Y, Saphire EO.

J Virol. 2015 Dec 9;90(4):1839-48. doi: 10.1128/JVI.01597-15. Print 2016 Feb 15.

15.

Suppressor of Cytokine Signaling 3 Is an Inducible Host Factor That Regulates Virus Egress during Ebola Virus Infection.

Okumura A, Rasmussen AL, Halfmann P, Feldmann F, Yoshimura A, Feldmann H, Kawaoka Y, Harty RN, Katze MG.

J Virol. 2015 Oct;89(20):10399-406. doi: 10.1128/JVI.01736-15. Epub 2015 Aug 5.

16.

Loss of Interleukin 1 Receptor Antagonist Enhances Susceptibility to Ebola Virus Infection.

Hill-Batorski L, Halfmann P, Marzi A, Lopes TJ, Neumann G, Feldmann H, Kawaoka Y.

J Infect Dis. 2015 Oct 1;212 Suppl 2:S329-35. doi: 10.1093/infdis/jiv335. Epub 2015 Jul 23.

17.

Ebola Conquers West Africa - More to Come?

Halfmann P, Neumann G, Feldmann H, Kawaoka Y.

EBioMedicine. 2014 Oct 13;1(1):2-3. doi: 10.1016/j.ebiom.2014.10.004. eCollection 2014 Nov. No abstract available.

18.

Identification of mammalian-adapting mutations in the polymerase complex of an avian H5N1 influenza virus.

Taft AS, Ozawa M, Fitch A, Depasse JV, Halfmann PJ, Hill-Batorski L, Hatta M, Friedrich TC, Lopes TJ, Maher EA, Ghedin E, Macken CA, Neumann G, Kawaoka Y.

Nat Commun. 2015 Jun 17;6:7491. doi: 10.1038/ncomms8491.

19.

Pseudoparticle neutralization assay for detecting ebola- neutralizing antibodies in biosafety level 2 settings.

Chin AW, Perera RA, Guan Y, Halfmann P, Kawaoka Y, Peiris M, Poon LL.

Clin Chem. 2015 Jun;61(6):885-6. doi: 10.1373/clinchem.2015.238204. Epub 2015 Mar 31. No abstract available.

20.

Vaccines. An Ebola whole-virus vaccine is protective in nonhuman primates.

Marzi A, Halfmann P, Hill-Batorski L, Feldmann F, Shupert WL, Neumann G, Feldmann H, Kawaoka Y.

Science. 2015 Apr 24;348(6233):439-42. doi: 10.1126/science.aaa4919. Epub 2015 Mar 26.

21.

Novel residues in avian influenza virus PB2 protein affect virulence in mammalian hosts.

Fan S, Hatta M, Kim JH, Halfmann P, Imai M, Macken CA, Le MQ, Nguyen T, Neumann G, Kawaoka Y.

Nat Commun. 2014 Oct 7;5:5021. doi: 10.1038/ncomms6021.

22.

The cytoprotective enzyme heme oxygenase-1 suppresses Ebola virus replication.

Hill-Batorski L, Halfmann P, Neumann G, Kawaoka Y.

J Virol. 2013 Dec;87(24):13795-802. doi: 10.1128/JVI.02422-13. Epub 2013 Oct 9.

23.

Structural rearrangement of ebola virus VP40 begets multiple functions in the virus life cycle.

Bornholdt ZA, Noda T, Abelson DM, Halfmann P, Wood MR, Kawaoka Y, Saphire EO.

Cell. 2013 Aug 15;154(4):763-74. doi: 10.1016/j.cell.2013.07.015.

24.

DNA topoisomerase 1 facilitates the transcription and replication of the Ebola virus genome.

Takahashi K, Halfmann P, Oyama M, Kozuka-Hata H, Noda T, Kawaoka Y.

J Virol. 2013 Aug;87(16):8862-9. doi: 10.1128/JVI.03544-12. Epub 2013 May 8.

25.

The spatio-temporal distribution dynamics of Ebola virus proteins and RNA in infected cells.

Nanbo A, Watanabe S, Halfmann P, Kawaoka Y.

Sci Rep. 2013;3:1206. doi: 10.1038/srep01206. Epub 2013 Feb 4.

26.

Marburg virus VP35 can both fully coat the backbone and cap the ends of dsRNA for interferon antagonism.

Bale S, Julien JP, Bornholdt ZA, Kimberlin CR, Halfmann P, Zandonatti MA, Kunert J, Kroon GJ, Kawaoka Y, MacRae IJ, Wilson IA, Saphire EO.

PLoS Pathog. 2012 Sep;8(9):e1002916. doi: 10.1371/journal.ppat.1002916. Epub 2012 Sep 13.

27.

Structure of an antibody in complex with its mucin domain linear epitope that is protective against Ebola virus.

Olal D, Kuehne AI, Bale S, Halfmann P, Hashiguchi T, Fusco ML, Lee JE, King LB, Kawaoka Y, Dye JM Jr, Saphire EO.

J Virol. 2012 Mar;86(5):2809-16. doi: 10.1128/JVI.05549-11. Epub 2011 Dec 14.

28.

A shared structural solution for neutralizing ebolaviruses.

Dias JM, Kuehne AI, Abelson DM, Bale S, Wong AC, Halfmann P, Muhammad MA, Fusco ML, Zak SE, Kang E, Kawaoka Y, Chandran K, Dye JM, Saphire EO.

Nat Struct Mol Biol. 2011 Nov 20;18(12):1424-7. doi: 10.1038/nsmb.2150.

29.

The Ebolavirus VP24 protein blocks phosphorylation of p38 mitogen-activated protein kinase.

Halfmann P, Neumann G, Kawaoka Y.

J Infect Dis. 2011 Nov;204 Suppl 3:S953-6. doi: 10.1093/infdis/jir325.

30.

Contribution of Sec61α to the life cycle of Ebola virus.

Iwasa A, Halfmann P, Noda T, Oyama M, Kozuka-Hata H, Watanabe S, Shimojima M, Watanabe T, Kawaoka Y.

J Infect Dis. 2011 Nov;204 Suppl 3:S919-26. doi: 10.1093/infdis/jir324.

31.

Ebolavirus is internalized into host cells via macropinocytosis in a viral glycoprotein-dependent manner.

Nanbo A, Imai M, Watanabe S, Noda T, Takahashi K, Neumann G, Halfmann P, Kawaoka Y.

PLoS Pathog. 2010 Sep 23;6(9):e1001121. doi: 10.1371/journal.ppat.1001121.

32.

Replication-deficient ebolavirus as a vaccine candidate.

Halfmann P, Ebihara H, Marzi A, Hatta Y, Watanabe S, Suresh M, Neumann G, Feldmann H, Kawaoka Y.

J Virol. 2009 Apr;83(8):3810-5. doi: 10.1128/JVI.00074-09. Epub 2009 Feb 11.

33.

Generation of biologically contained Ebola viruses.

Halfmann P, Kim JH, Ebihara H, Noda T, Neumann G, Feldmann H, Kawaoka Y.

Proc Natl Acad Sci U S A. 2008 Jan 29;105(4):1129-33. doi: 10.1073/pnas.0708057105. Epub 2008 Jan 22.

34.

Ebola virus (EBOV) VP24 inhibits transcription and replication of the EBOV genome.

Watanabe S, Noda T, Halfmann P, Jasenosky L, Kawaoka Y.

J Infect Dis. 2007 Nov 15;196 Suppl 2:S284-90.

PMID:
17940962
35.

Regions in Ebola virus VP24 that are important for nucleocapsid formation.

Noda T, Halfmann P, Sagara H, Kawaoka Y.

J Infect Dis. 2007 Nov 15;196 Suppl 2:S247-50.

PMID:
17940956
36.

Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus.

Kobasa D, Jones SM, Shinya K, Kash JC, Copps J, Ebihara H, Hatta Y, Kim JH, Halfmann P, Hatta M, Feldmann F, Alimonti JB, Fernando L, Li Y, Katze MG, Feldmann H, Kawaoka Y.

Nature. 2007 Jan 18;445(7125):319-23.

PMID:
17230189
37.

Characterization of a human H5N1 influenza A virus isolated in 2003.

Shinya K, Hatta M, Yamada S, Takada A, Watanabe S, Halfmann P, Horimoto T, Neumann G, Kim JH, Lim W, Guan Y, Peiris M, Kiso M, Suzuki T, Suzuki Y, Kawaoka Y.

J Virol. 2005 Aug;79(15):9926-32.

38.

Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus.

Kobasa D, Takada A, Shinya K, Hatta M, Halfmann P, Theriault S, Suzuki H, Nishimura H, Mitamura K, Sugaya N, Usui T, Murata T, Maeda Y, Watanabe S, Suresh M, Suzuki T, Suzuki Y, Feldmann H, Kawaoka Y.

Nature. 2004 Oct 7;431(7009):703-7.

PMID:
15470432
39.

Human influenza a viral genes responsible for the restriction of its replication in duck intestine.

Hatta M, Halfmann P, Wells K, Kawaoka Y.

Virology. 2002 Apr 10;295(2):250-5.

40.

Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses.

Hatta M, Gao P, Halfmann P, Kawaoka Y.

Science. 2001 Sep 7;293(5536):1840-2.

41.

Pragmatic assessment of physical activity.

Halfmann PL, Keller C, Allison M.

Nurse Pract Forum. 1997 Dec;8(4):160-5. Review.

PMID:
9481309

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