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Items: 33

1.

An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity.

Schmidt N, Domingues P, Golebiowski F, Patzina C, Tatham MH, Hay RT, Hale BG.

Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17399-17408. doi: 10.1073/pnas.1907031116. Epub 2019 Aug 7.

2.

Profiling host ANP32A splicing landscapes to predict influenza A virus polymerase adaptation.

Domingues P, Eletto D, Magnus C, Turkington HL, Schmutz S, Zagordi O, Lenk M, Beer M, Stertz S, Hale BG.

Nat Commun. 2019 Jul 30;10(1):3396. doi: 10.1038/s41467-019-11388-2.

3.

MHC class II proteins mediate cross-species entry of bat influenza viruses.

Karakus U, Thamamongood T, Ciminski K, Ran W, Günther SC, Pohl MO, Eletto D, Jeney C, Hoffmann D, Reiche S, Schinköthe J, Ulrich R, Wiener J, Hayes MGB, Chang MW, Hunziker A, Yángüez E, Aydillo T, Krammer F, Oderbolz J, Meier M, Oxenius A, Halenius A, Zimmer G, Benner C, Hale BG, García-Sastre A, Beer M, Schwemmle M, Stertz S.

Nature. 2019 Mar;567(7746):109-112. doi: 10.1038/s41586-019-0955-3. Epub 2019 Feb 20.

PMID:
30787439
4.

Unexpected Functional Divergence of Bat Influenza Virus NS1 Proteins.

Turkington HL, Juozapaitis M, Tsolakos N, Corrales-Aguilar E, Schwemmle M, Hale BG.

J Virol. 2018 Feb 12;92(5). pii: e02097-17. doi: 10.1128/JVI.02097-17. Print 2018 Mar 1.

5.

Functional Insights into ANP32A-Dependent Influenza A Virus Polymerase Host Restriction.

Domingues P, Hale BG.

Cell Rep. 2017 Sep 12;20(11):2538-2546. doi: 10.1016/j.celrep.2017.08.061.

6.

Human interactome of the influenza B virus NS1 protein.

Patzina C, Botting CH, García-Sastre A, Randall RE, Hale BG.

J Gen Virol. 2017 Sep;98(9):2267-2273. doi: 10.1099/jgv.0.000909. Epub 2017 Sep 4.

7.

Structure-Guided Functional Annotation of the Influenza A Virus NS1 Protein Reveals Dynamic Evolution of the p85β-Binding Site during Circulation in Humans.

Lopes AM, Domingues P, Zell R, Hale BG.

J Virol. 2017 Oct 13;91(21). pii: e01081-17. doi: 10.1128/JVI.01081-17. Print 2017 Nov 1.

8.

Global Reprogramming of Host SUMOylation during Influenza Virus Infection.

Domingues P, Golebiowski F, Tatham MH, Lopes AM, Taggart A, Hay RT, Hale BG.

Cell Rep. 2015 Nov 17;13(7):1467-1480. doi: 10.1016/j.celrep.2015.10.001. Epub 2015 Nov 5.

9.

Antigen presentation kinetics control T cell/dendritic cell interactions and follicular helper T cell generation in vivo.

Benson RA, MacLeod MK, Hale BG, Patakas A, Garside P, Brewer JM.

Elife. 2015 Aug 10;4. doi: 10.7554/eLife.06994.

10.

Novel Bat Influenza Virus NS1 Proteins Bind Double-Stranded RNA and Antagonize Host Innate Immunity.

Turkington HL, Juozapaitis M, Kerry PS, Aydillo T, Ayllon J, García-Sastre A, Schwemmle M, Hale BG.

J Virol. 2015 Oct;89(20):10696-701. doi: 10.1128/JVI.01430-15. Epub 2015 Aug 5.

11.

A single amino acid substitution in the novel H7N9 influenza A virus NS1 protein increases CPSF30 binding and virulence.

Ayllon J, Domingues P, Rajsbaum R, Miorin L, Schmolke M, Hale BG, García-Sastre A.

J Virol. 2014 Oct;88(20):12146-51. doi: 10.1128/JVI.01567-14. Epub 2014 Jul 30.

12.

Conformational plasticity of the influenza A virus NS1 protein.

Hale BG.

J Gen Virol. 2014 Oct;95(Pt 10):2099-105. doi: 10.1099/vir.0.066282-0. Epub 2014 Jun 13. Review.

PMID:
24928909
13.

Viral and host factors required for avian H5N1 influenza A virus replication in mammalian cells.

Zhang H, Hale BG, Xu K, Sun B.

Viruses. 2013 Jun 10;5(6):1431-46. doi: 10.3390/v5061431. Review.

14.

Interplay between viruses and host sumoylation pathways.

Everett RD, Boutell C, Hale BG.

Nat Rev Microbiol. 2013 Jun;11(6):400-11. doi: 10.1038/nrmicro3015. Epub 2013 Apr 29. Review.

PMID:
23624814
15.

Contribution of NS1 effector domain dimerization to influenza A virus replication and virulence.

Ayllon J, Russell RJ, García-Sastre A, Hale BG.

J Virol. 2012 Dec;86(23):13095-8. doi: 10.1128/JVI.02237-12. Epub 2012 Sep 19.

16.

Influenza A viruses and PI3K: are there time, place and manner restrictions?

Ayllon J, García-Sastre A, Hale BG.

Virulence. 2012 Jul 1;3(4):411-4. Epub 2012 Jun 22. Review. No abstract available.

17.

Influenza virus sequence feature variant type analysis: evidence of a role for NS1 in influenza virus host range restriction.

Noronha JM, Liu M, Squires RB, Pickett BE, Hale BG, Air GM, Galloway SE, Takimoto T, Schmolke M, Hunt V, Klem E, García-Sastre A, McGee M, Scheuermann RH.

J Virol. 2012 May;86(10):5857-66. doi: 10.1128/JVI.06901-11. Epub 2012 Mar 7.

18.

Strain-specific contribution of NS1-activated phosphoinositide 3-kinase signaling to influenza A virus replication and virulence.

Ayllon J, Hale BG, García-Sastre A.

J Virol. 2012 May;86(9):5366-70. doi: 10.1128/JVI.06722-11. Epub 2012 Feb 15.

19.

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species.

Schmolke M, Manicassamy B, Pena L, Sutton T, Hai R, Varga ZT, Hale BG, Steel J, Pérez DR, García-Sastre A.

PLoS Pathog. 2011 Aug;7(8):e1002186. doi: 10.1371/journal.ppat.1002186. Epub 2011 Aug 11.

20.

A transient homotypic interaction model for the influenza A virus NS1 protein effector domain.

Kerry PS, Ayllon J, Taylor MA, Hass C, Lewis A, García-Sastre A, Randall RE, Hale BG, Russell RJ.

PLoS One. 2011 Mar 28;6(3):e17946. doi: 10.1371/journal.pone.0017946.

21.

Inefficient control of host gene expression by the 2009 pandemic H1N1 influenza A virus NS1 protein.

Hale BG, Steel J, Medina RA, Manicassamy B, Ye J, Hickman D, Hai R, Schmolke M, Lowen AC, Perez DR, García-Sastre A.

J Virol. 2010 Jul;84(14):6909-22. doi: 10.1128/JVI.00081-10. Epub 2010 May 5.

22.

Mutations in the NS1 C-terminal tail do not enhance replication or virulence of the 2009 pandemic H1N1 influenza A virus.

Hale BG, Steel J, Manicassamy B, Medina RA, Ye J, Hickman D, Lowen AC, Perez DR, García-Sastre A.

J Gen Virol. 2010 Jul;91(Pt 7):1737-42. doi: 10.1099/vir.0.020925-0. Epub 2010 Mar 17.

23.

Species-specific antagonism of host ISGylation by the influenza B virus NS1 protein.

Versteeg GA, Hale BG, van Boheemen S, Wolff T, Lenschow DJ, García-Sastre A.

J Virol. 2010 May;84(10):5423-30. doi: 10.1128/JVI.02395-09. Epub 2010 Mar 10.

24.

Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein.

Hale BG, Kerry PS, Jackson D, Precious BL, Gray A, Killip MJ, Randall RE, Russell RJ.

Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):1954-9. doi: 10.1073/pnas.0910715107. Epub 2010 Jan 19.

25.

Innate immune evasion strategies of influenza viruses.

Hale BG, Albrecht RA, García-Sastre A.

Future Microbiol. 2010 Jan;5(1):23-41. doi: 10.2217/fmb.09.108. Review.

26.

Cation currents in human airway epithelial cells induced by infection with influenza A virus.

Gallacher M, Brown SG, Hale BG, Fearns R, Olver RE, Randall RE, Wilson SM.

J Physiol. 2009 Jul 1;587(Pt 13):3159-73. doi: 10.1113/jphysiol.2009.171223. Epub 2009 Apr 29.

27.

CDK/ERK-mediated phosphorylation of the human influenza A virus NS1 protein at threonine-215.

Hale BG, Knebel A, Botting CH, Galloway CS, Precious BL, Jackson D, Elliott RM, Randall RE.

Virology. 2009 Jan 5;383(1):6-11. doi: 10.1016/j.virol.2008.10.002. Epub 2008 Nov 13.

28.

The multifunctional NS1 protein of influenza A viruses.

Hale BG, Randall RE, Ortín J, Jackson D.

J Gen Virol. 2008 Oct;89(Pt 10):2359-76. doi: 10.1099/vir.0.2008/004606-0. Review.

PMID:
18796704
29.

Structure of an avian influenza A virus NS1 protein effector domain.

Hale BG, Barclay WS, Randall RE, Russell RJ.

Virology. 2008 Aug 15;378(1):1-5. doi: 10.1016/j.virol.2008.05.026. Epub 2008 Jun 27.

30.

Binding of influenza A virus NS1 protein to the inter-SH2 domain of p85 suggests a novel mechanism for phosphoinositide 3-kinase activation.

Hale BG, Batty IH, Downes CP, Randall RE.

J Biol Chem. 2008 Jan 18;283(3):1372-80. Epub 2007 Nov 20.

31.

PI3K signalling during influenza A virus infections.

Hale BG, Randall RE.

Biochem Soc Trans. 2007 Apr;35(Pt 2):186-7.

PMID:
17371234
32.

Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling.

Hale BG, Jackson D, Chen YH, Lamb RA, Randall RE.

Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14194-9. Epub 2006 Sep 8.

33.

Blood platelet size distribution in the Missouri bleeder swine.

Cooper RG, Hale BG, Cornell CN, Muhrer ME.

Life Sci II. 1971 Nov 8;10(21):1247-54. No abstract available.

PMID:
5138349

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