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Items: 48

1.

Processes discriminating adaptive and maladaptive Internet use among European adolescents highly engaged online.

Tzavela EC, Karakitsou C, Dreier M, Mavromati F, Wölfling K, Halapi E, Macarie G, Wójcik S, Veldhuis L, Tsitsika AK.

J Adolesc. 2015 Apr;40:34-47. doi: 10.1016/j.adolescence.2014.12.003. Epub 2015 Jan 22.

PMID:
25617526
2.

A sequence variant on 17q21 is associated with age at onset and severity of asthma.

Halapi E, Gudbjartsson DF, Jonsdottir GM, Bjornsdottir US, Thorleifsson G, Helgadottir H, Williams C, Koppelman GH, Heinzmann A, Boezen HM, Jonasdottir A, Blondal T, Gudjonsson SA, Jonasdottir A, Thorlacius T, Henry AP, Altmueller J, Krueger M, Shin HD, Uh ST, Cheong HS, Jonsdottir B, Ludviksson BR, Ludviksdottir D, Gislason D, Park CS, Deichmann K, Thompson PJ, Wjst M, Hall IP, Postma DS, Gislason T, Kong A, Jonsdottir I, Thorsteinsdottir U, Stefansson K.

Eur J Hum Genet. 2010 Aug;18(8):902-8. doi: 10.1038/ejhg.2010.38. Epub 2010 Apr 7.

3.

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction.

Gudbjartsson DF, Bjornsdottir US, Halapi E, Helgadottir A, Sulem P, Jonsdottir GM, Thorleifsson G, Helgadottir H, Steinthorsdottir V, Stefansson H, Williams C, Hui J, Beilby J, Warrington NM, James A, Palmer LJ, Koppelman GH, Heinzmann A, Krueger M, Boezen HM, Wheatley A, Altmuller J, Shin HD, Uh ST, Cheong HS, Jonsdottir B, Gislason D, Park CS, Rasmussen LM, Porsbjerg C, Hansen JW, Backer V, Werge T, Janson C, Jönsson UB, Ng MC, Chan J, So WY, Ma R, Shah SH, Granger CB, Quyyumi AA, Levey AI, Vaccarino V, Reilly MP, Rader DJ, Williams MJ, van Rij AM, Jones GT, Trabetti E, Malerba G, Pignatti PF, Boner A, Pescollderungg L, Girelli D, Olivieri O, Martinelli N, Ludviksson BR, Ludviksdottir D, Eyjolfsson GI, Arnar D, Thorgeirsson G, Deichmann K, Thompson PJ, Wjst M, Hall IP, Postma DS, Gislason T, Gulcher J, Kong A, Jonsdottir I, Thorsteinsdottir U, Stefansson K.

Nat Genet. 2009 Mar;41(3):342-7. doi: 10.1038/ng.323. Epub 2009 Feb 8.

PMID:
19198610
4.

Overview on the current status of asthma genetics.

Halapi E, Bjornsdottir US.

Clin Respir J. 2009 Jan;3(1):2-7. doi: 10.1111/j.1752-699X.2008.00119.x. Review.

PMID:
20298365
5.

Functional polymorphism and differential regulation of CYSLTR1 transcription in human airway smooth muscle and monocytes.

Duroudier NP, Sayers I, Castagna CC, Fenech AG, Halapi E, Swan C, Hall IP.

Cell Biochem Biophys. 2007;47(1):119-30.

PMID:
17406065
6.

Profiling of genes expressed in peripheral blood mononuclear cells predicts glucocorticoid sensitivity in asthma patients.

Hakonarson H, Bjornsdottir US, Halapi E, Bradfield J, Zink F, Mouy M, Helgadottir H, Gudmundsdottir AS, Andrason H, Adalsteinsdottir AE, Kristjansson K, Birkisson I, Arnason T, Andresdottir M, Gislason D, Gislason T, Gulcher JR, Stefansson K.

Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14789-94. Epub 2005 Oct 3.

7.

Contribution of ADAM33 polymorphisms to the population risk of asthma.

Blakey J, Halapi E, Bjornsdottir US, Wheatley A, Kristinsson S, Upmanyu R, Stefansson K, Hakonarson H, Hall IP.

Thorax. 2005 Apr;60(4):274-6.

8.

Population genomics of drug response.

Halapi E, Stefansson K, Hakonarson H.

Am J Pharmacogenomics. 2004;4(2):73-82. Review.

PMID:
15059030
9.

Association of vitamin D binding protein variants with chronic mucus hypersecretion in Iceland.

Laufs J, Andrason H, Sigvaldason A, Halapi E, Thorsteinsson L, Jónasson K, Söebech E, Gislason T, Gulcher JR, Stefansson K, Hakonarson H.

Am J Pharmacogenomics. 2004;4(1):63-8.

PMID:
14987123
10.

Genetic approaches to assessing evidence for a T helper type 1 cytokine defect in adult asthma.

Birkisson IF, Halapi E, Bjornsdottir US, Shkolny DL, Adalsteinsdottir E, Arnason T, Gislason D, Gislason T, Gulcher J, Stefansson K, Hakonarson H.

Am J Respir Crit Care Med. 2004 May 1;169(9):1007-13. Epub 2004 Feb 12.

PMID:
14962816
11.

Recent development in genomic and proteomic research for asthma.

Halapi E, Hakonarson H.

Curr Opin Pulm Med. 2004 Jan;10(1):22-30. Review.

PMID:
14749602
12.

Genetic analyses in asthma: current concepts and future directions.

Hakonarson H, Halapi E.

Am J Pharmacogenomics. 2002;2(3):155-66. Review.

PMID:
12383022
13.

Advances in the development of genetic markers for the diagnosis of disease and drug response.

Halapi E, Hakonarson H.

Expert Rev Mol Diagn. 2002 Sep;2(5):411-21. Review.

PMID:
12271813
14.

A major susceptibility gene for asthma maps to chromosome 14q24.

Hakonarson H, Bjornsdottir US, Halapi E, Palsson S, Adalsteinsdottir E, Gislason D, Finnbogason G, Gislason T, Kristjansson K, Arnason T, Birkisson I, Frigge ML, Kong A, Gulcher JR, Stefansson K.

Am J Hum Genet. 2002 Sep;71(3):483-91. Epub 2002 Jul 15.

15.

Allelic frequencies and patterns of single-nucleotide polymorphisms in candidate genes for asthma and atopy in Iceland.

Hakonarson H, Bjornsdottir US, Ostermann E, Arnason T, Adalsteinsdottir AE, Halapi E, Shkolny D, Kristjansson K, Gudnadottir SA, Frigge ML, Gislason D, Gislason T, Kong A, Gulcher J, Stefansson K.

Am J Respir Crit Care Med. 2001 Dec 1;164(11):2036-44.

PMID:
11739132
16.

Association between IL-1beta/TNF-alpha-induced glucocorticoid-sensitive changes in multiple gene expression and altered responsiveness in airway smooth muscle.

Hakonarson H, Halapi E, Whelan R, Gulcher J, Stefansson K, Grunstein MM.

Am J Respir Cell Mol Biol. 2001 Dec;25(6):761-71.

PMID:
11726403
17.

Kinetics of the T-cell receptor CD4 and CD8 V beta repertoire in HIV-1 vertically infected infants early treated with HAART.

Romiti ML, Cancrini C, Castelli-Gattinara G, Di Cesare S, Ciaffi P, Bernardi S, De Gasperi MR, Halapi E, Rossi P.

AIDS. 2001 Nov 9;15(16):2075-84.

PMID:
11684926
18.

T cell receptor usage in malignant diseases.

Halapi E, Jeddi-Tehrani M, Osterborg A, Mellstedt H.

Springer Semin Immunopathol. 1999;21(1):19-35. Review. No abstract available.

PMID:
10389230
19.

Diverse T-cell receptor CDR3 length patterns in human CD4+ and CD8+ T lymphocytes from newborns and adults.

Halapi E, Jeddi-Tehrani M, Blücher A, Andersson R, Rossi P, Wigzell H, Grunewald J.

Scand J Immunol. 1999 Feb;49(2):149-54.

20.

Oligoclonal T cells in human cancer.

Halapi E.

Med Oncol. 1998 Dec;15(4):203-11. Review.

PMID:
9951682
21.

T-cell expansions with conserved T-cell receptor beta chain motifs in the peripheral blood of HLA-DRB1*0401 positive patients with necrotizing vasculitis.

Grunewald J, Halapi E, Wahlström J, Giscombe R, Nityanand S, Sanjeevi C, Lefvert AK.

Blood. 1998 Nov 15;92(10):3737-44.

PMID:
9808568
22.

Correlation between HIV sequence evolution, specific immune response and clinical outcome in vertically infected infants.

Halapi E, Leitner T, Jansson M, Scarlatti G, Orlandi P, Plebani A, Romiti L, Albert J, Wigzell H, Rossi P.

AIDS. 1997 Nov 15;11(14):1709-17.

PMID:
9386805
23.

The role of virologic and immunologic factors in mother-to-child transmission of HIV-1.

Colognesi C, Halapi E, Jansson M, Hodara V, Steuer G, Tresoldi E, Leitner T, Scarlatti G.

Am J Reprod Immunol. 1997 Sep;38(3):197-200.

PMID:
9325492
24.

T cell repertoire in patients with multiple myeloma and monoclonal gammopathy of undetermined significance: clonal CD8+ T cell expansions are found preferentially in patients with a low tumor burden.

Halapi E, Werner A, Wahlström J, Osterborg A, Jeddi-Tehrani M, Yi Q, Janson CH, Wigzell H, Grunewald J, Mellstedt H.

Eur J Immunol. 1997 Sep;27(9):2245-52.

PMID:
9341766
25.

Role of immunity in maternal-infant HIV-1 transmission.

Jansson M, Orlandi P, Scarlatti G, Moschese V, Romiti ML, Cancrini C, Mancia L, Livadiotti S, Castelli-Gattinara G, Rossi P, Halapi E.

Acta Paediatr Suppl. 1997 Jun;421:39-45. Review.

PMID:
9240856
26.

RT-PCR topography of chronic psoriasis skin based on analysis of T-cell receptor B variable region gene usage.

Ahangari G, Halapi E, Tehrani MJ, Fransson J, Hammar H, Wigzell H.

Scand J Immunol. 1997 May;45(5):534-40.

27.
28.

Clonal CD8+ and CD52- T cells are induced in responding B cell lymphoma patients treated with Campath-1H (anti-CD52).

Osterborg A, Werner A, Halapi E, Lundin J, Harmenberg U, Wigzell H, Mellstedt H.

Eur J Haematol. 1997 Jan;58(1):5-13.

PMID:
9020367
29.

Detection of CD8 T-cell expansions with restricted T-cell receptor V gene usage in infants vertically infected by HIV-1.

Halapi E, Gigliotti D, Hodara V, Scarlatti G, Tovo PA, DeMaria A, Wigzell H, Rossi P.

AIDS. 1996 Dec;10(14):1621-6.

PMID:
8970681
30.

Genetic analysis of V3 domain sequences obtained from Uruguayan HIV type 1-infected individuals.

Fernández Medina RD, Jansson M, Halapi E, Russi JC, Libonatti O, Wigzell H.

AIDS Res Hum Retroviruses. 1996 Oct 10;12(15):1491-3. No abstract available.

PMID:
8893057
31.

RT-PCR based analysis of T-cell receptor B variable region gene usage in normal human breast skin resident T lymphocytes (SRT).

Ahangari G, Berg A, Jeddi-Tehrani M, Halapi E, Hammar H, Wigzell H.

Scand J Immunol. 1996 Oct;44(4):330-4.

PMID:
8845025
32.

Increased frequency of abnormal gamma delta T cells in blood of patients with inflammatory bowel diseases.

Söderström K, Bucht A, Halapi E, Grönberg A, Magnusson I, Kiessling R.

J Immunol. 1996 Mar 15;156(6):2331-9.

PMID:
8690925
33.

Lack of interleukin-2 (IL-2) expression and selective expression of IL-10 mRNA in human renal cell carcinoma.

Nakagomi H, Pisa P, Pisa EK, Yamamoto Y, Halapi E, Backlin K, Juhlin C, Kiessling R.

Int J Cancer. 1995 Nov 3;63(3):366-71.

PMID:
7591233
34.

Human gamma delta T-cells in the epithelium of the gut and in the inflamed synovial tissue preferentially express the V gamma 8 T-cell receptor chain.

Söderström K, Bucht A, Halapi E, Lundqvist C, Grönberg A, Nilsson E, Orsini DL, van de Wal Y, Koning F, Hammarström ML, et al.

Ann N Y Acad Sci. 1995 Jul 7;756:406-9. No abstract available.

PMID:
7645859
35.

CD8+ T lymphocytes provide helper activity for IgE synthesis in human immunodeficiency virus-infected patients with hyper-IgE.

Paganelli R, Scala E, Ansotegui IJ, Ausiello CM, Halapi E, Fanales-Belasio E, D'Offizi G, Mezzaroma I, Pandolfi F, Fiorilli M, Cassone A, Aiuti F.

J Exp Med. 1995 Jan 1;181(1):423-8.

36.

High expression of V gamma 8 is a shared feature of human gamma delta T cells in the epithelium of the gut and in the inflamed synovial tissue.

Söderström K, Bucht A, Halapi E, Lundqvist C, Grönberg A, Nilsson E, Orsini DL, van de Wal Y, Koning F, Hammarström ML, et al.

J Immunol. 1994 Jun 15;152(12):6017-27.

PMID:
8207227
37.

Neutralizing antibodies and viral characteristics in mother-to-child transmission of HIV-1.

Scarlatti G, Leitner T, Hodara V, Halapi E, Rossi P, Albert J, Fenyö EM.

AIDS. 1993 Nov;7 Suppl 2:S45-8.

PMID:
8161445
38.

Analysis of the HIV-1 envelope V3-loop sequences from ten mother-child pairs.

Scarlatti G, Leitner T, Halapi E, Wahlberg J, Jansson M, Wigzell H, Fenyö EM, Albert J, Uhlén M, Rossi P.

Ann N Y Acad Sci. 1993 Oct 29;693:277-80. No abstract available.

PMID:
8267278
39.

Cytotoxic activity and T cell receptor repertoire in tumor-infiltrating lymphocytes of adrenal cell carcinomas.

Yamamoto Y, Backlin K, Nakagomi H, Halapi E, Juhlin C, Bucht A, Kiessling R.

Cancer Immunol Immunother. 1993 Aug;37(3):163-8.

PMID:
8334679
40.

Analysis of heterogeneous viral populations by direct DNA sequencing.

Leitner T, Halapi E, Scarlatti G, Rossi P, Albert J, Fenyö EM, Uhlén M.

Biotechniques. 1993 Jul;15(1):120-7.

PMID:
8363827
41.

Comparison of variable region 3 sequences of human immunodeficiency virus type 1 from infected children with the RNA and DNA sequences of the virus populations of their mothers.

Scarlatti G, Leitner T, Halapi E, Wahlberg J, Marchisio P, Clerici-Schoeller MA, Wigzell H, Fenyö EM, Albert J, Uhlén M, et al.

Proc Natl Acad Sci U S A. 1993 Mar 1;90(5):1721-5.

42.

Regulation of lymphocyte aggregation and proliferation through adhesion molecule CD54 (ICAM-1).

Grönberg A, Halapi E, Ferm M, Petersson M, Patarroyo M.

Cell Immunol. 1993 Mar;147(1):12-24.

PMID:
8096436
43.

Restricted T cell receptor V-beta and J-beta usage in T cells from interleukin-2-cultured lymphocytes of ovarian and renal carcinomas.

Halapi E, Yamamoto Y, Juhlin C, Jeddi-Tehrani M, Grunewald J, Andersson R, Hising C, Masucci G, Mellstedt H, Kiessling R.

Cancer Immunol Immunother. 1993;36(3):191-7.

PMID:
8439980
44.

Selective expression of interleukin 10, interferon gamma, and granulocyte-macrophage colony-stimulating factor in ovarian cancer biopsies.

Pisa P, Halapi E, Pisa EK, Gerdin E, Hising C, Bucht A, Gerdin B, Kiessling R.

Proc Natl Acad Sci U S A. 1992 Aug 15;89(16):7708-12.

45.
46.

Diverse effect of cytokine treatment of tumor cells on specific versus non-specific cytotoxicity.

Naganuma H, Halapi E, Masucci G, Hansson M, Wersäll P, Hising C, Venkateswaran S, Mellstedt H, Kiessling R.

Med Oncol Tumor Pharmacother. 1992;9(1):25-33.

PMID:
1341317
47.

Mycobacterial-induced cytotoxic T cells as well as nonspecific killer cells derived from healthy individuals and leprosy patients.

Kaleab B, Ottenoff T, Converse P, Halapi E, Tadesse G, Rottenberg M, Kiessling R.

Eur J Immunol. 1990 Dec;20(12):2651-9.

PMID:
2269329
48.

Synovial cells responding to a 65-kDa mycobacterial heat shock protein have a high proportion of a TcR gamma delta subtype uncommon in peripheral blood.

Söderström K, Halapi E, Nilsson E, Grönberg A, van Embden J, Klareskog L, Kiessling R.

Scand J Immunol. 1990 Nov;32(5):503-15.

PMID:
2148638

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