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Items: 1 to 50 of 619

1.

Stage-specific embryonic antigen-4 is a histological marker reflecting the malignant behavior of prostate cancer.

Nakamura Y, Miyata Y, Matsuo T, Shida Y, Hakariya T, Ohba K, Taima T, Ito A, Suda T, Hakomori SI, Saito S, Sakai H.

Glycoconj J. 2019 Oct;36(5):409-418. doi: 10.1007/s10719-019-09882-2. Epub 2019 Jun 26.

2.

Functional role of glycosphingolipids in contact inhibition of growth in a human mammary epithelial cell line.

Huang X, Schurman N, Handa K, Hakomori S.

FEBS Lett. 2017 Jul;591(13):1918-1928. doi: 10.1002/1873-3468.12709. Epub 2017 Jun 22.

3.

Changes of glycoconjugate expression profiles during early development.

Handa K, Hakomori SI.

Glycoconj J. 2017 Dec;34(6):693-699. doi: 10.1007/s10719-016-9684-0. Epub 2016 Jun 18. Review.

PMID:
27318475
4.

GM3 and cancer.

Hakomori SI, Handa K.

Glycoconj J. 2015 Feb;32(1-2):1-8. doi: 10.1007/s10719-014-9572-4. Epub 2015 Jan 23. Review.

PMID:
25613425
5.

Obituary: Steven Bruce Levery (1949–2014).

Clausen H, Nudelman E, Hakomori SI.

Glycoconj J. 2014 Jul;31(5):339-40. No abstract available.

PMID:
25105190
6.

Efficient synthesis of chloro-derivatives of sialosyllactosylceramide, and their enhanced inhibitory effect on epidermal growth factor receptor activation.

Kawashima N, Qu H, Lobaton M, Zhu Z, Sollogoub M, Cavenee WK, Handa K, Hakomori SI, Zhang Y.

Oncol Lett. 2014 Apr;7(4):933-940. Epub 2014 Feb 17.

7.

Sialic acid-binding lectin (leczyme) induces apoptosis to malignant mesothelioma and exerts synergistic antitumor effects with TRAIL.

Tatsuta T, Hosono M, Takahashi K, Omoto T, Kariya Y, Sugawara S, Hakomori S, Nitta K.

Int J Oncol. 2014 Feb;44(2):377-84. doi: 10.3892/ijo.2013.2192. Epub 2013 Nov 28.

8.

Involvement of ER stress in apoptosis induced by sialic acid-binding lectin (leczyme) from bullfrog eggs.

Tatsuta T, Hosono M, Miura Y, Sugawara S, Kariya Y, Hakomori S, Nitta K.

Int J Oncol. 2013 Dec;43(6):1799-808. doi: 10.3892/ijo.2013.2128. Epub 2013 Oct 4.

9.

Sialic acid-binding lectin (leczyme) induces caspase-dependent apoptosis-mediated mitochondrial perturbation in Jurkat cells.

Tatsuta T, Hosono M, Sugawara S, Kariya Y, Ogawa Y, Hakomori S, Nitta K.

Int J Oncol. 2013 Nov;43(5):1402-12. doi: 10.3892/ijo.2013.2092. Epub 2013 Sep 5.

10.

Domain composition of rhamnose-binding lectin from shishamo smelt eggs and its carbohydrate-binding profiles.

Hosono M, Sugawara S, Tatsuta T, Hikita T, Kominami J, Nakamura-Tsuruta S, Hirabayashi J, Kawsar SM, Ozeki Y, Hakomori SI, Nitta K.

Fish Physiol Biochem. 2013 Dec;39(6):1619-30. doi: 10.1007/s10695-013-9814-6. Epub 2013 Jun 6.

PMID:
23740100
11.

Differential expression profiles of glycosphingolipids in human breast cancer stem cells vs. cancer non-stem cells.

Liang YJ, Ding Y, Levery SB, Lobaton M, Handa K, Hakomori SI.

Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):4968-73. doi: 10.1073/pnas.1302825110. Epub 2013 Mar 11.

12.

Self-recognition of high-mannose type glycans mediating adhesion of embryonal fibroblasts.

Yoon SJ, Utkina N, Sadilek M, Yagi H, Kato K, Hakomori SI.

Glycoconj J. 2013 Jul;30(5):485-96. doi: 10.1007/s10719-012-9449-3. Epub 2012 Sep 25.

PMID:
23007868
13.

Glycosylation effects on cancer development.

Hakomori SI, Cummings RD.

Glycoconj J. 2012 Dec;29(8-9):565-6. doi: 10.1007/s10719-012-9448-4. No abstract available.

PMID:
22996057
14.

Induction of epithelial-mesenchymal transition with O-glycosylated oncofetal fibronectin.

Ding Y, Gelfenbeyn K, Freire-de-Lima L, Handa K, Hakomori SI.

FEBS Lett. 2012 Jun 21;586(13):1813-20. doi: 10.1016/j.febslet.2012.05.020. Epub 2012 May 26.

15.

Carbohydrate to carbohydrate interaction in development process and cancer progression.

Handa K, Hakomori SI.

Glycoconj J. 2012 Dec;29(8-9):627-37. doi: 10.1007/s10719-012-9380-7. Epub 2012 May 18. Review. Erratum in: Glycoconj J. 2012 Dec;29(8-9):639.

PMID:
22610315
16.

MRP1 expressed on Burkitt's lymphoma cells was depleted by catfish egg lectin through Gb3-glycosphingolipid and enhanced cytotoxic effect of drugs.

Fujii Y, Sugawara S, Araki D, Kawano T, Tatsuta T, Takahashi K, Kawsar SM, Matsumoto R, Kanaly RA, Yasumitsu H, Ozeki Y, Hosono M, Miyagi T, Hakomori SI, Takayanagi M, Nitta K.

Protein J. 2012 Jan;31(1):15-26. doi: 10.1007/s10930-011-9369-2.

PMID:
22083453
17.

Involvement of O-glycosylation defining oncofetal fibronectin in epithelial-mesenchymal transition process.

Freire-de-Lima L, Gelfenbeyn K, Ding Y, Mandel U, Clausen H, Handa K, Hakomori SI.

Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17690-5. doi: 10.1073/pnas.1115191108. Epub 2011 Oct 17.

18.

Regulation of epidermal growth factor receptor through interaction of ganglioside GM3 with GlcNAc of N-linked glycan of the receptor: demonstration in ldlD cells.

Guan F, Handa K, Hakomori SI.

Neurochem Res. 2011 Sep;36(9):1645-53. doi: 10.1007/s11064-010-0379-9. Epub 2011 Jan 4.

PMID:
21203834
19.

Functional role of gangliotetraosylceramide in epithelial-to-mesenchymal transition process induced by hypoxia and by TGF-{beta}.

Guan F, Schaffer L, Handa K, Hakomori SI.

FASEB J. 2010 Dec;24(12):4889-903. doi: 10.1096/fj.10-162107. Epub 2010 Aug 18.

20.

Glycosyl conjugates of biotinylated diaminopyridine applied for study of carbohydrate-to-carbohydrate interaction.

Utkina N, Yoon SJ, Hakomori SI.

Glycoconj J. 2010 Aug;27(6):601-11. doi: 10.1007/s10719-010-9304-3. Epub 2010 Aug 10.

PMID:
20697955
21.

Dimeric Le(a) (Le(a)-on-Le(a)) status of beta-haptoglobin in sera of colon cancer, chronic inflammatory disease and normal subjects.

Park SY, Yoon SJ, Hakomori SI, Kim JM, Kim JY, Bernert B, Ullman T, Itzkowitz SH, Kim JH.

Int J Oncol. 2010 May;36(5):1291-7.

PMID:
20372805
22.

Human monoclonal antibody GNX-8 directed to extended type 1 chain: Specific binding to human colorectal cancer.

Yang MC, Hsu FL, Handa K, Hakomori S, Lee MH, Liu LY, Chang SY, Ting J, Wen JY, Ishida I, Chang TH.

Int J Cancer. 2009 Dec 21. [Epub ahead of print]

23.

N-glycosylation status of beta-haptoglobin in sera of patients with prostate cancer vs. benign prostate diseases.

Yoon SJ, Park SY, Pang PC, Gallagher J, Gottesman JE, Dell A, Kim JH, Hakomori SI.

Int J Oncol. 2010 Jan;36(1):193-203.

24.

Glycosynaptic microdomains controlling tumor cell phenotype through alteration of cell growth, adhesion, and motility.

Hakomori SI.

FEBS Lett. 2010 May 3;584(9):1901-6. doi: 10.1016/j.febslet.2009.10.065. Epub 2009 Oct 27. Review.

25.

Control of cell motility by interaction of gangliosides, tetraspanins, and epidermal growth factor receptor in A431 versus KB epidermoid tumor cells.

Park SY, Yoon SJ, Freire-de-Lima L, Kim JH, Hakomori SI.

Carbohydr Res. 2009 Aug 17;344(12):1479-86. doi: 10.1016/j.carres.2009.04.032. Epub 2009 May 13.

PMID:
19559406
26.

N-glycosylation status of beta-haptoglobin in sera of patients with colon cancer, chronic inflammatory diseases and normal subjects.

Park SY, Yoon SJ, Jeong YT, Kim JM, Kim JY, Bernert B, Ullman T, Itzkowitz SH, Kim JH, Hakomori SI.

Int J Cancer. 2010 Jan 1;126(1):142-55. doi: 10.1002/ijc.24685.

27.

Specific glycosphingolipids mediate epithelial-to-mesenchymal transition of human and mouse epithelial cell lines.

Guan F, Handa K, Hakomori SI.

Proc Natl Acad Sci U S A. 2009 May 5;106(18):7461-6. doi: 10.1073/pnas.0902368106. Epub 2009 Apr 20.

28.

Quantitative analysis of EGFR affinity to immobilized glycolipids by surface plasmon resonance.

Haga Y, Hakomori SI, Hatanaka K.

Carbohydr Res. 2008 Dec 8;343(18):3034-8. doi: 10.1016/j.carres.2008.09.002. Epub 2008 Sep 9.

PMID:
18828994
29.

Ganglioside GM2/GM3 complex affixed on silica nanospheres strongly inhibits cell motility through CD82/cMet-mediated pathway.

Todeschini AR, Dos Santos JN, Handa K, Hakomori SI.

Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1925-30. doi: 10.1073/pnas.0709619104. Epub 2008 Feb 6.

30.

Effect of lipid mimetics of GM3 and lyso-GM3 dimer on EGF receptor tyrosine kinase and EGF-induced signal transduction.

Haga Y, Hatanaka K, Hakomori SI.

Biochim Biophys Acta. 2008 Mar;1780(3):393-404. Epub 2007 Nov 5.

31.

Functional role of glycosphingolipids and gangliosides in control of cell adhesion, motility, and growth, through glycosynaptic microdomains.

Regina Todeschini A, Hakomori SI.

Biochim Biophys Acta. 2008 Mar;1780(3):421-33. Epub 2007 Oct 22. Review.

32.

Structure and function of glycosphingolipids and sphingolipids: recollections and future trends.

Hakomori SI.

Biochim Biophys Acta. 2008 Mar;1780(3):325-46. Epub 2007 Sep 6. Review.

33.

Glycosylation status of haptoglobin in sera of patients with prostate cancer vs. benign prostate disease or normal subjects.

Fujimura T, Shinohara Y, Tissot B, Pang PC, Kurogochi M, Saito S, Arai Y, Sadilek M, Murayama K, Dell A, Nishimura S, Hakomori SI.

Int J Cancer. 2008 Jan 1;122(1):39-49.

34.

Lyso-GM3, its dimer, and multimer: their synthesis, and their effect on epidermal growth factor-induced receptor tyrosine kinase.

Murozuka Y, Watanabe N, Hatanaka K, Hakomori SI.

Glycoconj J. 2007 Dec;24(9):551-63. Epub 2007 Jul 19.

PMID:
17638075
35.

Self-recognition of N-linked glycans with multivalent GlcNAc, determined as ceramide mimetic conjugate.

Yoon SJ, Ikeda S, Sadilek M, Hakomori SI, Ishida H, Kiso M.

Glycobiology. 2007 Sep;17(9):1007-14. Epub 2007 Jul 2.

PMID:
17609198
36.

Le(x) glycan mediates homotypic adhesion of embryonal cells independently from E-cadherin: a preliminary note.

Handa K, Takatani-Nakase T, Larue L, Stemmler MP, Kemler R, Hakomori SI.

Biochem Biophys Res Commun. 2007 Jun 22;358(1):247-52. Epub 2007 Apr 24.

PMID:
17481582
37.

Ganglioside GM2-tetraspanin CD82 complex inhibits met and its cross-talk with integrins, providing a basis for control of cell motility through glycosynapse.

Todeschini AR, Dos Santos JN, Handa K, Hakomori SI.

J Biol Chem. 2007 Mar 16;282(11):8123-33. Epub 2007 Jan 10.

38.

Epidermal growth factor receptor tyrosine kinase is modulated by GM3 interaction with N-linked GlcNAc termini of the receptor.

Yoon SJ, Nakayama K, Hikita T, Handa K, Hakomori SI.

Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):18987-91. Epub 2006 Dec 1.

39.

Interaction of N-linked glycans, having multivalent GlcNAc termini, with GM3 ganglioside.

Yoon SJ, Nakayama K, Takahashi N, Yagi H, Utkina N, Wang HY, Kato K, Sadilek M, Hakomori SI.

Glycoconj J. 2006 Dec;23(9):639-49. Epub 2006 Nov 18. Erratum in: Glycoconj J. 2007 Apr;24(2-3):181.

PMID:
17115280
40.

A catalytic carbohydrate contributes to bacterial antibiotic resistance.

de Figueiredo P, Terra B, Anand JK, Hikita T, Sadilek M, Monks DE, Lenskiy A, Hakomori S, Nester EW.

Extremophiles. 2007 Jan;11(1):133-43. Epub 2006 Oct 18.

PMID:
17048043
41.

Introduction. Professor Yasuo Inoue: 1934-2005.

Kitajima K, Khoo KH, Hakomori SI.

Glycoconj J. 2006 Jul;23(5-6):273-6. No abstract available.

PMID:
16897171
42.

Establishment and characterization of a new erythroblastic leukemia cell line, EEB: phosphatidylglucoside-mediated erythroid differentiation and apoptosis.

Kawano-Yamamoto C, Muroi K, Nagatsuka Y, Higuchi M, Kikuchi S, Nagai T, Hakomori SI, Ozawa K.

Leuk Res. 2006 Jul;30(7):829-39. Epub 2005 Dec 5.

PMID:
16332389
43.
44.

De-N-acetyllactotriaosylceramide as a novel cationic glycosphingolipid of bovine brain white matter: isolation and characterization.

Hikita T, Tadano-Aritomi K, Iida-Tanaka N, Ishizuka I, Hakomori S.

Biochemistry. 2005 Jul 12;44(27):9555-62.

PMID:
15996110
45.

Effect of ganglioside and tetraspanins in microdomains on interaction of integrins with fibroblast growth factor receptor.

Toledo MS, Suzuki E, Handa K, Hakomori S.

J Biol Chem. 2005 Apr 22;280(16):16227-34. Epub 2005 Feb 14.

46.

RM2 antigen (beta1,4-GalNAc-disialyl-Lc4) as a new marker for prostate cancer.

Saito S, Egawa S, Endoh M, Ueno S, Ito A, Numahata K, Satoh M, Kuwao S, Baba S, Hakomori S, Arai Y.

Int J Cancer. 2005 May 20;115(1):105-13.

47.

Reversion of the Jun-induced oncogenic phenotype by enhanced synthesis of sialosyllactosylceramide (GM3 ganglioside).

Miura Y, Kainuma M, Jiang H, Velasco H, Vogt PK, Hakomori S.

Proc Natl Acad Sci U S A. 2004 Nov 16;101(46):16204-9. Epub 2004 Nov 8.

49.

Sphingosine-dependent apoptosis: a unified concept based on multiple mechanisms operating in concert.

Suzuki E, Handa K, Toledo MS, Hakomori S.

Proc Natl Acad Sci U S A. 2004 Oct 12;101(41):14788-93. Epub 2004 Oct 4.

50.

Glycosynapses: microdomains controlling carbohydrate-dependent cell adhesion and signaling.

Hakomori S.

An Acad Bras Cienc. 2004 Sep;76(3):553-72. Epub 2004 Aug 23. Review.

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