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Items: 26

1.

Why Do Countries Regulate Environmental Health Risks Differently? A Theoretical Perspective.

Clahsen SCS, van Kamp I, Hakkert BC, Vermeire TG, Piersma AH, Lebret E.

Risk Anal. 2019 Feb;39(2):439-461. doi: 10.1111/risa.13165. Epub 2018 Aug 15.

PMID:
30110518
2.

International regulatory needs for development of an IATA for non-genotoxic carcinogenic chemical substances.

Jacobs MN, Colacci A, Louekari K, Luijten M, Hakkert BC, Paparella M, Vasseur P.

ALTEX. 2016;33(4):359-392. doi: 10.14573/altex.1601201. Epub 2016 Apr 27.

3.

An integrative test strategy for cancer hazard identification.

Luijten M, Olthof ED, Hakkert BC, Rorije E, van der Laan JW, Woutersen RA, van Benthem J.

Crit Rev Toxicol. 2016 Aug;46(7):615-39. doi: 10.3109/10408444.2016.1171294. Epub 2016 May 3.

PMID:
27142259
4.

Evaluation of the performance of the reduced local lymph node assay for skin sensitization testing.

Ezendam J, Muller A, Hakkert BC, van Loveren H.

Regul Toxicol Pharmacol. 2013 Jun;66(1):66-71. doi: 10.1016/j.yrtph.2013.02.006. Epub 2013 Feb 28.

PMID:
23459101
5.

On the impact of second generation mating and offspring in multi-generation reproductive toxicity studies on classification and labelling of substances in Europe.

Rorije E, Muller A, Beekhuijzen ME, Hass U, Heinrich-Hirsch B, Paparella M, Schenk E, Ulbrich B, Hakkert BC, Piersma AH.

Regul Toxicol Pharmacol. 2011 Nov;61(2):251-60. doi: 10.1016/j.yrtph.2011.08.005. Epub 2011 Aug 23.

PMID:
21878359
6.

Combined retrospective analysis of 498 rat multi-generation reproductive toxicity studies: on the impact of parameters related to F1 mating and F2 offspring.

Piersma AH, Rorije E, Beekhuijzen ME, Cooper R, Dix DJ, Heinrich-Hirsch B, Martin MT, Mendez E, Muller A, Paparella M, Ramsingh D, Reaves E, Ridgway P, Schenk E, Stachiw L, Ulbrich B, Hakkert BC.

Reprod Toxicol. 2011 May;31(4):392-401. doi: 10.1016/j.reprotox.2010.11.013. Epub 2010 Dec 3.

PMID:
21130863
7.

Finding maximal transcriptome differences between reprotoxic and non-reprotoxic phthalate responses in rat testis.

Yuan X, Jonker MJ, de Wilde J, Verhoef A, Wittink FR, van Benthem J, Bessems JG, Hakkert BC, Kuiper RV, van Steeg H, Breit TM, Luijten M.

J Appl Toxicol. 2011 Jul;31(5):421-30. doi: 10.1002/jat.1601. Epub 2010 Nov 9.

PMID:
21061450
8.

Retrospective analysis of relative parameter sensitivity in multi-generation reproductive toxicity studies.

Dang ZC, Rorije E, Esch TH, Muller A, Hakkert BC, Piersma AH.

Reprod Toxicol. 2009 Sep;28(2):196-202. doi: 10.1016/j.reprotox.2009.04.009. Epub 2009 Apr 22.

PMID:
19393313
9.

A retrospective analysis of developmental toxicity studies in rat and rabbit: what is the added value of the rabbit as an additional test species?

Janer G, Slob W, Hakkert BC, Vermeire T, Piersma AH.

Regul Toxicol Pharmacol. 2008 Mar;50(2):206-17. doi: 10.1016/j.yrtph.2007.11.007. Epub 2007 Nov 28.

PMID:
18171599
10.

Quantitative extrapolation of in vitro whole embryo culture embryotoxicity data to developmental toxicity in vivo using the benchmark dose approach.

Piersma AH, Janer G, Wolterink G, Bessems JG, Hakkert BC, Slob W.

Toxicol Sci. 2008 Jan;101(1):91-100. Epub 2007 Sep 27.

PMID:
17905734
11.

A retrospective analysis of the added value of the rat two-generation reproductive toxicity study versus the rat subchronic toxicity study.

Janer G, Hakkert BC, Piersma AH, Vermeire T, Slob W.

Reprod Toxicol. 2007 Jul;24(1):103-13. Epub 2007 May 18.

PMID:
17600672
12.

A retrospective analysis of the two-generation study: what is the added value of the second generation?

Janer G, Hakkert BC, Slob W, Vermeire T, Piersma AH.

Reprod Toxicol. 2007 Jul;24(1):97-102. Epub 2007 May 6.

PMID:
17572063
13.

Comparative in vitro-in vivo percutaneous penetration of the fungicide ortho-phenylphenol.

Cnubben NH, Elliott GR, Hakkert BC, Meuling WJ, van de Sandt JJ.

Regul Toxicol Pharmacol. 2002 Apr;35(2 Pt 1):198-208.

PMID:
12052004
14.
15.

Comparative in vitro-in vivo percutaneous absorption of the pesticide propoxur.

van de Sandt JJ, Meuling WJ, Elliott GR, Cnubben NH, Hakkert BC.

Toxicol Sci. 2000 Nov;58(1):15-22.

PMID:
11053536
16.

Assessment factors for human health risk assessment: a discussion paper.

Vermeire T, Stevenson H, Peiters MN, Rennen M, Slob W, Hakkert BC.

Crit Rev Toxicol. 1999 Sep;29(5):439-90. Review.

PMID:
10521133
17.

Toxicological risk assessment of worker exposure to pesticides: some general principles.

de Raat WK, Stevenson H, Hakkert BC, van Hemmen JJ.

Regul Toxicol Pharmacol. 1997 Jun;25(3):204-10. Review. No abstract available.

PMID:
9237322
18.
20.
22.

Monocytes enhance the bidirectional release of type I plasminogen activator inhibitor by endothelial cells.

Hakkert BC, Rentenaar JM, van Mourik JA.

Blood. 1990 Dec 1;76(11):2272-8.

PMID:
2257301
23.

A three-dimensional model system to study the interactions between human leukocytes and endothelial cells.

Hakkert BC, Rentenaar JM, Van Aken WG, Roos D, Van Mourik JA.

Eur J Immunol. 1990 Dec;20(12):2775-81.

PMID:
1980113
24.

Distinct adhesive properties of granulocytes and monocytes to endothelial cells under static and stirred conditions.

Kuijpers TW, Hakkert BC, van Mourik JA, Roos D.

J Immunol. 1990 Oct 15;145(8):2588-94.

PMID:
1976697
25.
26.

Genotoxicity testing of cigarette-smoke condensate in the SCE and HGPRT assays with V79 Chinese hamster cells.

Jongen WM, Hakkert BC, van der Hoeven JC.

Food Chem Toxicol. 1985 Jun;23(6):603-7.

PMID:
4040105

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