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Items: 1 to 50 of 68

1.

An adjuvant-modulated vaccine response in human whole blood.

Hakimi J, Azizi A, Ausar SF, Todryk SM, Rahman N, Brookes RH.

Hum Vaccin Immunother. 2017 Sep 2;13(9):2130-2134. doi: 10.1080/21645515.2017.1337616. Epub 2017 Jun 12.

2.

Screening Vaccine Formulations in Fresh Human Whole Blood.

Hakimi J, Aboutorabian S, To F, Ausar SF, Rahman N, Brookes RH.

Methods Mol Biol. 2017;1494:295-304.

PMID:
27718203
3.

A high ratio of IC31(®) adjuvant to antigen is necessary for H4 TB vaccine immunomodulation.

Aboutorabian S, Hakimi J, Boudet F, Montano S, Dookie A, Roque C, Ausar SF, Rahman N, Brookes RH.

Hum Vaccin Immunother. 2015;11(6):1449-55. doi: 10.1080/21645515.2015.1023970.

4.

Screening vaccine formulations for biological activity using fresh human whole blood.

Brookes RH, Hakimi J, Ha Y, Aboutorabian S, Ausar SF, Hasija M, Smith SG, Todryk SM, Dockrell HM, Rahman N.

Hum Vaccin Immunother. 2014;10(4):1129-35. Epub 2014 Jan 8.

5.

A sensitive flow cytometry-based cytotoxic T-lymphocyte assay through detection of cleaved caspase 3 in target cells.

He L, Hakimi J, Salha D, Miron I, Dunn P, Radvanyi L.

J Immunol Methods. 2005 Sep;304(1-2):43-59.

PMID:
16076473
6.

The gene associated with trichorhinophalangeal syndrome in humans is overexpressed in breast cancer.

Radvanyi L, Singh-Sandhu D, Gallichan S, Lovitt C, Pedyczak A, Mallo G, Gish K, Kwok K, Hanna W, Zubovits J, Armes J, Venter D, Hakimi J, Shortreed J, Donovan M, Parrington M, Dunn P, Oomen R, Tartaglia J, Berinstein NL.

Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):11005-10. Epub 2005 Jul 25.

7.

Prophylactic and therapeutic effects of a humanized monoclonal antibody against the IL-2 receptor (DACLIZUMAB) on collagen-induced arthritis (CIA) in rhesus monkeys.

Brok HP, Tekoppele JM, Hakimi J, Kerwin JA, Nijenhuis EM, De Groot CW, Bontrop RE, 't Hart BA.

Clin Exp Immunol. 2001 Apr;124(1):134-41.

8.

Is uterine papillary serous adenocarcinoma a manifestation of the hereditary breast-ovarian cancer syndrome?

Goshen R, Chu W, Elit L, Pal T, Hakimi J, Ackerman I, Fyles A, Mitchell M, Narod SA.

Gynecol Oncol. 2000 Dec;79(3):477-81.

PMID:
11104623
9.

Successful in vivo blockade of CD25 (high-affinity interleukin 2 receptor) on T cells by administration of humanized anti-Tac antibody to patients with psoriasis.

Krueger JG, Walters IB, Miyazawa M, Gilleaudeau P, Hakimi J, Light S, Sherr A, Gottlieb AB.

J Am Acad Dermatol. 2000 Sep;43(3):448-58.

PMID:
10954656
10.

Significance of the CAG repeat polymorphism of the androgen receptor gene in prostate cancer progression.

Nam RK, Elhaji Y, Krahn MD, Hakimi J, Ho M, Chu W, Sweet J, Trachtenberg J, Jewett MA, Narod SA.

J Urol. 2000 Aug;164(2):567-72.

PMID:
10893645
11.

A rapid fluorescent multiplexed-PCR analysis (FMPA) for founder mutations in the BRCA1 and BRCA2 genes.

Kuperstein G, Foulkes WD, Ghadirian P, Hakimi J, Narod SA.

Clin Genet. 2000 Mar;57(3):213-20.

PMID:
10782928
12.

Daclizumab rapidly saturates interleukin-2 receptor-alpha (CD25) on lymph node lymphocytes in children.

Savo AM, Book BK, Henson S, Hakimi J, Pescovitz MD.

Transplant Proc. 1999 Feb-Mar;31(1-2):1182-3. No abstract available.

PMID:
10083528
13.

Treatment of uveitis with recombinant human interleukin-13.

Roberge FG, de Smet MD, Benichou J, Kriete MF, Raber J, Hakimi J.

Br J Ophthalmol. 1998 Oct;82(10):1195-8.

14.

Androgen receptor variants with short glutamine or glycine repeats may identify unique subpopulations of men with prostate cancer.

Hakimi JM, Schoenberg MP, Rondinelli RH, Piantadosi S, Barrack ER.

Clin Cancer Res. 1997 Sep;3(9):1599-608.

15.

Collagen-induced arthritis in rhesus monkeys: evaluation of markers for inflammation and joint degradation.

Hart BA, Bank RA, De Roos JA, Brok H, Jonker M, Theuns HM, Hakimi J, Te Koppele JM.

Br J Rheumatol. 1998 Mar;37(3):314-23.

PMID:
9566674
16.

Bispecific humanized anti-IL-2 receptor alpha beta antibodies inhibitory for both IL-2- and IL-15-mediated proliferation.

Pilson RS, Levin W, Desai B, Reik LM, Lin P, Korkmaz-Duffy E, Campbell E, Tso JY, Kerwin JA, Hakimi J.

J Immunol. 1997 Aug 1;159(3):1543-56.

PMID:
9233654
17.

A phase I trial of humanized anti-interleukin 2 receptor antibody in renal transplantation.

Vincenti F, Lantz M, Birnbaum J, Garovoy M, Mould D, Hakimi J, Nieforth K, Light S.

Transplantation. 1997 Jan 15;63(1):33-8.

PMID:
9000657
18.

Humanized antibodies against the alpha-chain of the IL-2 receptor and against the beta-chain shared by the IL-2 and IL-15 receptors in a monkey uveitis model of autoimmune diseases.

Guex-Crosier Y, Raber J, Chan CC, Kriete MS, Benichou J, Pilson RS, Kerwin JA, Waldmann TA, Hakimi J, Roberge FG.

J Immunol. 1997 Jan 1;158(1):452-8.

PMID:
8977222
20.

Androgen-receptor gene structure and function in prostate cancer.

Hakimi JM, Rondinelli RH, Schoenberg MP, Barrack ER.

World J Urol. 1996;14(5):329-37. Review.

PMID:
8912473
21.
22.

Preparation of a bispecific F(ab')2 targeted to the human IL-2 receptor.

Tso JY, Wang SL, Levin W, Hakimi J.

J Hematother. 1995 Oct;4(5):389-94.

PMID:
8581374
23.

IL-12 regulation of parasite antigen-driven IgE production in human helminth infections.

King CL, Hakimi J, Shata MT, Medhat A.

J Immunol. 1995 Jul 1;155(1):454-61.

PMID:
7602117
24.

Activated T cells induce interleukin-12 production by monocytes via CD40-CD40 ligand interaction.

Shu U, Kiniwa M, Wu CY, Maliszewski C, Vezzio N, Hakimi J, Gately M, Delespesse G.

Eur J Immunol. 1995 Apr;25(4):1125-8.

PMID:
7537673
25.

Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity.

Ling P, Gately MK, Gubler U, Stern AS, Lin P, Hollfelder K, Su C, Pan YC, Hakimi J.

J Immunol. 1995 Jan 1;154(1):116-27.

PMID:
7527811
26.
27.

Humanized antibody directed to the IL-2 receptor beta-chain prolongs primate cardiac allograft survival.

Tinubu SA, Hakimi J, Kondas JA, Bailon P, Familletti PC, Spence C, Crittenden MD, Parenteau GL, Dirbas FM, Tsudo M, et al.

J Immunol. 1994 Nov 1;153(9):4330-8.

PMID:
7930631
28.

Interleukin 12 is produced in vivo during endotoxemia and stimulates synthesis of gamma interferon.

Heinzel FP, Rerko RM, Ling P, Hakimi J, Schoenhaut DS.

Infect Immun. 1994 Oct;62(10):4244-9.

29.

Interleukin 12, interferon gamma, and tumor necrosis factor alpha are the key cytokines of the generalized Shwartzman reaction.

Ozmen L, Pericin M, Hakimi J, Chizzonite RA, Wysocka M, Trinchieri G, Gately M, Garotta G.

J Exp Med. 1994 Sep 1;180(3):907-15.

30.

Binding sites for bacteriophage HP1 integrase on its DNA substrates.

Hakimi JM, Scocca JJ.

J Biol Chem. 1994 Aug 19;269(33):21340-5.

31.

IL-12 influences intrathymic T cell development.

Godfrey DI, Kennedy J, Gately MK, Hakimi J, Hubbard BR, Zlotnik A.

J Immunol. 1994 Mar 15;152(6):2729-35.

PMID:
7511624
32.

Neutralization of IL-12 decreases resistance to Listeria in SCID and C.B-17 mice. Reversal by IFN-gamma.

Tripp CS, Gately MK, Hakimi J, Ling P, Unanue ER.

J Immunol. 1994 Feb 15;152(4):1883-7.

PMID:
7907107
33.

Microsatellite mutation (CAG24-->18) in the androgen receptor gene in human prostate cancer.

Schoenberg MP, Hakimi JM, Wang S, Bova GS, Epstein JI, Fischbeck KH, Isaacs WB, Walsh PC, Barrack ER.

Biochem Biophys Res Commun. 1994 Jan 14;198(1):74-80.

PMID:
8292051
34.

Identification of sites on the human Fc epsilon RI alpha subunit which are involved in binding human and rat IgE.

Mallamaci MA, Chizzonite R, Griffin M, Nettleton M, Hakimi J, Tsien WH, Kochan JP.

J Biol Chem. 1993 Oct 15;268(29):22076-83.

35.

Demonstration of the high-affinity IgE receptor on human Langerhans cells in normal and diseased skin.

Grabbe J, Haas N, Hamann K, Kolde G, Hakimi J, Czarnetzki BM.

Br J Dermatol. 1993 Aug;129(2):120-3.

PMID:
7544604
36.

Humanized Mik beta 1, a humanized antibody to the IL-2 receptor beta-chain that acts synergistically with humanized anti-TAC.

Hakimi J, Ha VC, Lin P, Campbell E, Gately MK, Tsudo M, Payne PW, Waldmann TA, Grant AJ, Tsien WH, et al.

J Immunol. 1993 Jul 15;151(2):1075-85.

PMID:
8335891
37.

Purification and characterization of human recombinant IgE-Fc fragments that bind to the human high affinity IgE receptor.

Basu M, Hakimi J, Dharm E, Kondas JA, Tsien WH, Pilson RS, Lin P, Gilfillan A, Haring P, Braswell EH, et al.

J Biol Chem. 1993 Jun 25;268(18):13118-27.

38.

Autoantibodies against the high-affinity IgE receptor as a cause of histamine release in chronic urticaria.

Hide M, Francis DM, Grattan CE, Hakimi J, Kochan JP, Greaves MW.

N Engl J Med. 1993 Jun 3;328(22):1599-604.

39.
40.

A new structure-activity model for Ah receptor binding. Polychlorinated dibenzo-p-dioxins and dibenzofurans.

Kafafi SA, Afeefy HY, Said HK, Hakimi JM.

Chem Res Toxicol. 1992 Nov-Dec;5(6):856-62.

PMID:
1336992
41.

Conservation of signal transduction mechanisms via the human Fc epsilon RI alpha after transfection into a rat mast cell line, RBL 2H3.

Gilfillan AM, Kado-Fong H, Wiggan GA, Hakimi J, Kent U, Kochan JP.

J Immunol. 1992 Oct 1;149(7):2445-51.

PMID:
1382104
42.

Human epidermal Langerhans cells express the high affinity receptor for immunoglobulin E (Fc epsilon RI).

Bieber T, de la Salle H, Wollenberg A, Hakimi J, Chizzonite R, Ring J, Hanau D, de la Salle C.

J Exp Med. 1992 May 1;175(5):1285-90.

43.

Reduced immunogenicity and improved pharmacokinetics of humanized anti-Tac in cynomolgus monkeys.

Hakimi J, Chizzonite R, Luke DR, Familletti PC, Bailon P, Kondas JA, Pilson RS, Lin P, Weber DV, Spence C, et al.

J Immunol. 1991 Aug 15;147(4):1352-9.

PMID:
1869828
44.

High affinity human IgE receptor (Fc epsilon RI). Analysis of functional domains of the alpha-subunit with monoclonal antibodies.

Riske F, Hakimi J, Mallamaci M, Griffin M, Pilson B, Tobkes N, Lin P, Danho W, Kochan J, Chizzonite R.

J Biol Chem. 1991 Jun 15;266(17):11245-51.

45.

Localization in human interleukin 2 of the binding site to the alpha chain (p55) of the interleukin 2 receptor.

Sauvé K, Nachman M, Spence C, Bailon P, Campbell E, Tsien WH, Kondas JA, Hakimi J, Ju G.

Proc Natl Acad Sci U S A. 1991 Jun 1;88(11):4636-40.

46.

Anti-Tac-H, a humanized antibody to the interleukin 2 receptor, prolongs primate cardiac allograft survival.

Brown PS Jr, Parenteau GL, Dirbas FM, Garsia RJ, Goldman CK, Bukowski MA, Junghans RP, Queen C, Hakimi J, Benjamin WR, et al.

Proc Natl Acad Sci U S A. 1991 Apr 1;88(7):2663-7.

47.

The alpha subunit of the human IgE receptor (FcERI) is sufficient for high affinity IgE binding.

Hakimi J, Seals C, Kondas JA, Pettine L, Danho W, Kochan J.

J Biol Chem. 1990 Dec 25;265(36):22079-81.

48.

Human interleukin-2 anti-idiotypes.

Osheroff PL, Gately MK, Skaleris DA, Wilson DE, Seals CM, Hakimi J, Tsien WH.

Hybridoma. 1988 Oct;7(5):417-27.

PMID:
3264260
49.

Identification of specific residues of human interleukin 2 that affect binding to the 70-kDa subunit (p70) of the interleukin 2 receptor.

Collins L, Tsien WH, Seals C, Hakimi J, Weber D, Bailon P, Hoskings J, Greene WC, Toome V, Ju G.

Proc Natl Acad Sci U S A. 1988 Oct;85(20):7709-13.

50.

Isolation of the gene coding for the alpha subunit of the human high affinity IgE receptor.

Kochan J, Pettine LF, Hakimi J, Kishi K, Kinet JP.

Nucleic Acids Res. 1988 Apr 25;16(8):3584. No abstract available.

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