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Oesophageal cancer incidence in 20-year follow-up in a population-based sample of 12 000 middle-age men with or without Helicobacter pylori infection in Finland.

Vohlonen IJ, Hakama M, Härkönen M, Malila N, Pukkala E, Koistinen V, Sipponen P.

Gut. 2018 Jun;67(6):1201-1202. doi: 10.1136/gutjnl-2017-314913. Epub 2017 Aug 31. No abstract available.


Spillover improved survival in non-invited patients of the colorectal cancer screening programme.

Miettinen J, Malila N, Hakama M, Pitkäniemi J.

J Med Screen. 2017 Jan 1:969141317718220. doi: 10.1177/0969141317718220. [Epub ahead of print]


Challenges in evaluation of screening for gastric cancer among men based on nonrandomized design.

Vohlonen I, Härkönen M, Malila N, Pukkala E, Sipponen P, Koistinen V, Hakama M.

Acta Oncol. 2017 Jul;56(7):917-922. doi: 10.1080/0284186X.2016.1278304. Epub 2017 Feb 23.


Predicting the effectiveness of the Finnish population-based colorectal cancer screening programme.

Chiu SY, Malila N, Yen AM, Chen SL, Fann JC, Hakama M.

J Med Screen. 2017 Dec;24(4):182-188. doi: 10.1177/0969141316684524. Epub 2017 Jan 13.


Effect of characteristics of women on attendance in blind and non-blind randomised trials: analysis of recruitment data from the EPHT Trial.

Veerus P, Fischer K, Hemminki E, Hovi SL, Hakama M.

BMJ Open. 2016 Oct 18;6(10):e011099. doi: 10.1136/bmjopen-2016-011099.


Design-corrected variation by centre in mortality reduction in the ERSPC randomised prostate cancer screening trial.

Hakama M, Moss SM, Stenman UH, Roobol MJ, Zappa M, Carlsson S, Randazzo M, Nelen V, Hugosson J.

J Med Screen. 2017 Jun;24(2):98-103. doi: 10.1177/0969141316652174. Epub 2016 Aug 9.


Risk of gastric cancer in Helicobacter pylori infection in a 15-year follow-up.

Vohlonen I, Pukkala E, Malila N, Härkönen M, Hakama M, Koistinen V, Sipponen P.

Scand J Gastroenterol. 2016 Oct;51(10):1159-64. doi: 10.1080/00365521.2016.1183225. Epub 2016 Jun 24.


Longitudinal biobanks-based study on the joint effects of infections, nutrition and hormones on risk of prostate cancer.

Lumme S, Tenkanen L, Langseth H, Gislefoss R, Hakama M, Stattin P, Hallmans G, Adlercreutz H, Saikku P, Stenman UH, Tuohimaa P, Luostarinen T, Dillner J.

Acta Oncol. 2016 Jul;55(7):839-45. doi: 10.3109/0284186X.2016.1139178. Epub 2016 Feb 15.


Use of hospital resources in the Finnish colorectal cancer screening programme: a randomised health services study.

Mäklin S, Hakama M, Rissanen P, Malila N.

BMJ Open Gastroenterol. 2015 Dec 21;2(1):e000063. doi: 10.1136/bmjgast-2015-000063. eCollection 2015.


Age-related incidence of cervical cancer supports two aetiological components: a population-based register study.

Seppä K, Pitkäniemi J, Malila N, Hakama M.

BJOG. 2016 Apr;123(5):772-8. doi: 10.1111/1471-0528.13754. Epub 2015 Nov 24.


Effectiveness of screening for colorectal cancer with a faecal occult-blood test, in Finland.

Pitkäniemi J, Seppä K, Hakama M, Malminiemi O, Palva T, Vuoristo MS, Järvinen H, Paimela H, Pikkarainen P, Anttila A, Elovainio L, Hakulinen T, Karjalainen S, Pylkkänen L, Rautalahti M, Sarkeala T, Vertio H, Malila N.

BMJ Open Gastroenterol. 2015 Jun 8;2(1):e000034. doi: 10.1136/bmjgast-2015-000034. eCollection 2015.


Effect of Screening on Variation in Cervical Cancer Survival by Socioeconomic Determinants--a Study from Rural South India.

Thulaseedharan JV, Malila N, Swaminathan R, Esmy PO, Cherian M, Hakama M, Muwonge R, Sankaranarayanan R.

Asian Pac J Cancer Prev. 2015;16(13):5237-42.


Risk of invasive cancer among women visually screened and colposcopy triaged by trained nurses in rural South India.

Thulaseedharan JV, Malila N, Esmy PO, Muwonge R, Hakama M, Sankaranarayanan R.

Int J Gynaecol Obstet. 2015 May;129(2):104-8. doi: 10.1016/j.ijgo.2014.11.019. Epub 2015 Jan 31.


The Finnish prostate cancer screening trial: analyses on the screening failures.

Kilpeläinen TP, Tammela TL, Malila N, Hakama M, Santti H, Määttänen L, Stenman UH, Kujala P, Auvinen A.

Int J Cancer. 2015 May 15;136(10):2437-43. doi: 10.1002/ijc.29300. Epub 2014 Nov 10.


Screening and prostate cancer mortality: results of the European Randomised Study of Screening for Prostate Cancer (ERSPC) at 13 years of follow-up.

Schröder FH, Hugosson J, Roobol MJ, Tammela TL, Zappa M, Nelen V, Kwiatkowski M, Lujan M, Määttänen L, Lilja H, Denis LJ, Recker F, Paez A, Bangma CH, Carlsson S, Puliti D, Villers A, Rebillard X, Hakama M, Stenman UH, Kujala P, Taari K, Aus G, Huber A, van der Kwast TH, van Schaik RH, de Koning HJ, Moss SM, Auvinen A; ERSPC Investigators.

Lancet. 2014 Dec 6;384(9959):2027-35. doi: 10.1016/S0140-6736(14)60525-0. Epub 2014 Aug 6.


Sensitivity, effect and overdiagnosis in screening for cancers with detectable pre-invasive phase.

Hakama M, Pokhrel A, Malila N, Hakulinen T.

Int J Cancer. 2015 Feb 15;136(4):928-35. doi: 10.1002/ijc.29053. Epub 2014 Jul 7.


Effect of a pre-screening survey on attendance in colorectal cancer screening: a double-randomized study in Finland.

Helander S, Hakama M, Malila N.

J Med Screen. 2014 Jun;21(2):82-8. doi: 10.1177/0969141314534229. Epub 2014 May 6.


Outcomes of medical and surgical treatment for lower urinary tract symptoms (benign prostatic obstruction)--a population-based cohort study.

Pöyhönen A, Auvinen A, Häkkinen JT, Koskimäki J, Hakama M, Tammela TL.

Int J Clin Pract. 2014 Mar;68(3):349-55. doi: 10.1111/ijcp.12318. Epub 2013 Dec 22.


My 50 years.

Hakama M.

Acta Oncol. 2013 Jun;52(5):883-5. doi: 10.3109/0284186X.2013.791028. No abstract available.


Effect of screening on the risk estimates of socio demographic factors on cervical cancer - a large cohort study from rural India.

Thulaseedharan JV, Malila N, Hakama M, Esmy PO, Cherian M, Swaminathan R, Muwonge R, Sankaranarayanan R.

Asian Pac J Cancer Prev. 2013;14(1):589-94.


Prostate cancer mortality in the Finnish randomized screening trial.

Kilpeläinen TP, Tammela TL, Malila N, Hakama M, Santti H, Määttänen L, Stenman UH, Kujala P, Auvinen A.

J Natl Cancer Inst. 2013 May 15;105(10):719-25. doi: 10.1093/jnci/djt038. Epub 2013 Mar 11.


Detection rates of precancerous and cancerous cervical lesions within one screening round of primary human papillomavirus DNA testing: prospective randomised trial in Finland.

Leinonen MK, Nieminen P, Lönnberg S, Malila N, Hakama M, Pokhrel A, Laurila P, Tarkkanen J, Anttila A.

BMJ. 2012 Nov 29;345:e7789. doi: 10.1136/bmj.e7789.


Empirical evaluation of grouping of lower urinary tract symptoms: principal component analysis of Tampere Ageing Male Urological Study data.

Pöyhönen A, Häkkinen JT, Koskimäki J, Hakama M, Tammela TL, Auvinen A.

BJU Int. 2013 Mar;111(3):467-73. doi: 10.1111/j.1464-410X.2012.11593.x. Epub 2012 Oct 26.


The HPV test has similar sensitivity but more overdiagnosis than the Pap test--a randomised health services study on cervical cancer screening in Finland.

Malila N, Leinonen M, Kotaniemi-Talonen L, Laurila P, Tarkkanen J, Hakama M.

Int J Cancer. 2013 May 1;132(9):2141-7. doi: 10.1002/ijc.27850. Epub 2012 Oct 12.


Socio demographic and reproductive risk factors for cervical cancer - a large prospective cohort study from rural India.

Thulaseedharan JV, Malila N, Hakama M, Esmy PO, Cheriyan M, Swaminathan R, Muwonge R, Sankaranarayanan R.

Asian Pac J Cancer Prev. 2012;13(6):2991-5.


Tobacco use or body mass--do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study.

Pednekar MS, Hakama M, Gupta PC.

PLoS One. 2012;7(7):e39443. doi: 10.1371/journal.pone.0039443. Epub 2012 Jul 27.


Prevalence and bother of postmicturition dribble in Finnish men aged 30-80 years: Tampere Ageing Male Urologic Study (TAMUS).

Pöyhönen A, Auvinen A, Koskimäki J, Hakama M, Tammela TL, Häkkinen JT.

Scand J Urol Nephrol. 2012 Dec;46(6):418-23. doi: 10.3109/00365599.2012.702786. Epub 2012 Jul 27.


Effect of intervention on decision making of treatment for disease progression, prostate-specific antigen biochemical failure and prostate cancer death.

Huang RC, Auvinen A, Hakama M, Tammela TL, Ala-Opas M, Leppilahti M, Vornanen T, Chen HH.

Health Expect. 2014 Dec;17(6):776-83. doi: 10.1111/j.1369-7625.2012.00802.x. Epub 2012 Jul 19.


Results from a blind and a non-blind randomised trial run in parallel: experience from the Estonian Postmenopausal Hormone Therapy (EPHT) Trial.

Veerus P, Fischer K, Hakama M, Hemminki E; EPHT Trial.

BMC Med Res Methodol. 2012 Apr 4;12:44. doi: 10.1186/1471-2288-12-44.


Randomised health services studies.

Hakama M, Malila N, Dillner J.

Int J Cancer. 2012 Dec 15;131(12):2898-902. doi: 10.1002/ijc.27561. Epub 2012 Apr 24.


Prostate-cancer mortality at 11 years of follow-up.

Schröder FH, Hugosson J, Roobol MJ, Tammela TL, Ciatto S, Nelen V, Kwiatkowski M, Lujan M, Lilja H, Zappa M, Denis LJ, Recker F, Páez A, Määttänen L, Bangma CH, Aus G, Carlsson S, Villers A, Rebillard X, van der Kwast T, Kujala PM, Blijenberg BG, Stenman UH, Huber A, Taari K, Hakama M, Moss SM, de Koning HJ, Auvinen A; ERSPC Investigators.

N Engl J Med. 2012 Mar 15;366(11):981-90. doi: 10.1056/NEJMoa1113135. Erratum in: N Engl J Med. 2012 May 31;366(22):2137.


The impact of interscreening interval and age on prostate cancer screening with prostate-specific antigen.

Wu GH, Auvinen A, Yen AM, Hakama M, Tammela TL, Stenman UH, Kujala P, Ruutu M, Chen HH.

Eur Urol. 2012 May;61(5):1011-8. doi: 10.1016/j.eururo.2012.01.008. Epub 2012 Jan 14.


A stochastic model for survival of early prostate cancer with adjustments for leadtime, length bias, and over-detection.

Wu GH, Auvinen A, Yen AM, Hakama M, Walter SD, Chen HH.

Biom J. 2012 Jan;54(1):20-44. doi: 10.1002/bimj.201000107. Epub 2011 Dec 23.


Number of screens for overdetection as an indicator of absolute risk of overdiagnosis in prostate cancer screening.

Wu GH, Auvinen A, Määttänen L, Tammela TL, Stenman UH, Hakama M, Yen AM, Chen HH.

Int J Cancer. 2012 Sep 15;131(6):1367-75. doi: 10.1002/ijc.27340. Epub 2012 Jan 11.


Effects of annual vs triennial mammography interval on breast cancer incidence and mortality in ages 40-49 in Finland.

Parvinen I, Chiu S, Pylkkänen L, Klemi P, Immonen-Räihä P, Kauhava L, Malila N, Hakama M.

Br J Cancer. 2011 Oct 25;105(9):1388-91. doi: 10.1038/bjc.2011.372. Epub 2011 Sep 20.


Prevalence of hesitancy in 30-80-year-old Finnish men: Tampere Ageing Male Urological Study (TAMUS).

Pöyhönen A, Häkkinen JT, Koskimäki J, Hakama M, Tammela TL, Auvinen A.

BJU Int. 2012 May;109(9):1360-4. doi: 10.1111/j.1464-410X.2011.10443.x. Epub 2011 Aug 24.


Loss-adjusted hospital and population-based survival of cancer patients.

Ganesh B, Swaminathan R, Mathew A, Sankaranarayanan R, Hakama M.

IARC Sci Publ. 2011;(162):15-21.


Coverage and performance of colorectal cancer screening with the faecal occult blood test in Finland.

Malila N, Palva T, Malminiemi O, Paimela H, Anttila A, Hakulinen T, Järvinen H, Kotisaari ML, Pikkarainen P, Rautalahti M, Sankila R, Vertio H, Hakama M.

J Med Screen. 2011;18(1):18-23. doi: 10.1258/jms.2010.010036.


High-throughput epidemiology: combining existing data from the Nordic countries in health-related collaborative research.

Olsen J, Brønnum-Hansen H, Gissler M, Hakama M, Hjern A, Kamper-Jørgensen F, Rafnsson V, Tell GS, Thaulow I, Thygesen LC.

Scand J Public Health. 2010 Nov;38(7):777-9. doi: 10.1177/1403494810377681. No abstract available.


Lead-time in the European Randomised Study of Screening for Prostate Cancer.

Finne P, Fallah M, Hakama M, Ciatto S, Hugosson J, de Koning H, Moss S, Nelen V, Auvinen A.

Eur J Cancer. 2010 Nov;46(17):3102-8. doi: 10.1016/j.ejca.2010.09.034.


The role of parents, friends and teachers in adolescents' cigarette smoking and tombak dipping in Sudan.

El-Amin Sel-T, Nwaru BI, Ginawi I, Pisani P, Hakama M.

Tob Control. 2011 Mar;20(2):94-9. doi: 10.1136/tc.2010.038091. Epub 2010 Oct 13.


Cervical cancer patterns with automation-assisted and conventional cytological screening: a randomized study.

Anttila A, Pokhrel A, Kotaniemi-Talonen L, Hakama M, Malila N, Nieminen P.

Int J Cancer. 2011 Mar 1;128(5):1204-12. doi: 10.1002/ijc.25677. Epub 2010 Nov 12.


Analytical decision model for sample size and effectiveness projections for use in planning a population-based randomized controlled trial of colorectal cancer screening.

Chiu SY, Malila N, Yen AM, Anttila A, Hakama M, Chen HH.

J Eval Clin Pract. 2011 Feb;17(1):123-9. doi: 10.1111/j.1365-2753.2010.01378.x. Epub 2010 Sep 12.


Causes of death among patients with multiple sclerosis.

Sumelahti ML, Hakama M, Elovaara I, Pukkala E.

Mult Scler. 2010 Dec;16(12):1437-42. doi: 10.1177/1352458510379244. Epub 2010 Sep 8.


Lifestyle factors and varicose veins: does cross-sectional design result in underestimate of the risk?

Ahti TM, Mäkivaara LA, Luukkaala T, Hakama M, Laurikka JO.

Phlebology. 2010 Aug;25(4):201-6. doi: 10.1258/phleb.2009.009031.


Intensified screening among high risk women within the organised screening programme for cervical cancer in Finland.

Kotaniemi-Talonen L, Malila N, Anttila A, Nieminen P, Hakama M.

Acta Oncol. 2011 Jan;50(1):106-11. doi: 10.3109/0284186X.2010.496793. Epub 2010 Jun 21.


Rate of cervical cancer, severe intraepithelial neoplasia, and adenocarcinoma in situ in primary HPV DNA screening with cytology triage: randomised study within organised screening programme.

Anttila A, Kotaniemi-Talonen L, Leinonen M, Hakama M, Laurila P, Tarkkanen J, Malila N, Nieminen P.

BMJ. 2010 Apr 27;340:c1804. doi: 10.1136/bmj.c1804.


Ulysses contracts for the doctor and for the patient.

Hansson MG, Hakama M.

Contemp Clin Trials. 2010 May;31(3):202-6. doi: 10.1016/j.cct.2010.03.004. Epub 2010 Mar 19.


The risk of congestive heart failure is increased in persons with varicose veins.

Mäkivaara LA, Ahti TM, Luukkaala T, Hakama M, Laurikka JO.

Int Angiol. 2009 Dec;28(6):452-7.


Effect of family history on the risk of varicose veins is affected by differential misclassification.

Ahti TM, Mäkivaara LA, Luukkaala T, Hakama M, Laurikka JO.

J Clin Epidemiol. 2010 Jun;63(6):686-90. doi: 10.1016/j.jclinepi.2009.10.003. Epub 2010 Jan 8.


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