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Best matches for Hajnóczky G[au]:

Mitochondrial Nanotunnels. Vincent AE et al. Trends Cell Biol. (2017)

Intracellular Ca<sup>2+</sup> Sensing: Its Role in Calcium Homeostasis and Signaling. Bagur R et al. Mol Cell. (2017)

ROS Control Mitochondrial Motility through p38 and the Motor Adaptor Miro/Trak. Debattisti V et al. Cell Rep. (2017)

Search results

Items: 1 to 50 of 122

1.

Coming together to define membrane contact sites.

Scorrano L, De Matteis MA, Emr S, Giordano F, Hajnóczky G, Kornmann B, Lackner LL, Levine TP, Pellegrini L, Reinisch K, Rizzuto R, Simmen T, Stenmark H, Ungermann C, Schuldiner M.

Nat Commun. 2019 Mar 20;10(1):1287. doi: 10.1038/s41467-019-09253-3. Review.

2.

Redox regulation of ER and mitochondrial Ca2+ signaling in cell survival and death.

Joseph SK, Booth DM, Young MP, Hajnóczky G.

Cell Calcium. 2019 May;79:89-97. doi: 10.1016/j.ceca.2019.02.006. Epub 2019 Feb 16. Review.

PMID:
30889512
3.

MICU1 Interacts with the D-Ring of the MCU Pore to Control Its Ca2+ Flux and Sensitivity to Ru360.

Paillard M, Csordás G, Huang KT, Várnai P, Joseph SK, Hajnóczky G.

Mol Cell. 2018 Nov 15;72(4):778-785.e3. doi: 10.1016/j.molcel.2018.09.008. Epub 2018 Oct 25.

PMID:
30454562
4.

MICU1 Confers Protection from MCU-Dependent Manganese Toxicity.

Wettmarshausen J, Goh V, Huang KT, Arduino DM, Tripathi U, Leimpek A, Cheng Y, Pittis AA, Gabaldón T, Mokranjac D, Hajnóczky G, Perocchi F.

Cell Rep. 2018 Nov 6;25(6):1425-1435.e7. doi: 10.1016/j.celrep.2018.10.037.

5.

Mitochondrial fusion and Bid-mediated mitochondrial apoptosis are perturbed by alcohol with distinct dependence on its metabolism.

Naghdi S, Slovinsky WS, Madesh M, Rubin E, Hajnóczky G.

Cell Death Dis. 2018 Oct 9;9(10):1028. doi: 10.1038/s41419-018-1070-3.

6.

Redox regulation of type-I inositol trisphosphate receptors in intact mammalian cells.

Joseph SK, Young MP, Alzayady K, Yule DI, Ali M, Booth DM, Hajnóczky G.

J Biol Chem. 2018 Nov 9;293(45):17464-17476. doi: 10.1074/jbc.RA118.005624. Epub 2018 Sep 18.

PMID:
30228182
7.

Mitochondrial dynamics in adaptive and maladaptive cellular stress responses.

Eisner V, Picard M, Hajnóczky G.

Nat Cell Biol. 2018 Jul;20(7):755-765. doi: 10.1038/s41556-018-0133-0. Epub 2018 Jun 27. Review. No abstract available.

PMID:
29950571
8.

Endoplasmic Reticulum-Mitochondrial Contactology: Structure and Signaling Functions.

Csordás G, Weaver D, Hajnóczky G.

Trends Cell Biol. 2018 Jul;28(7):523-540. doi: 10.1016/j.tcb.2018.02.009. Epub 2018 Mar 24. Review.

9.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G.

Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Review.

10.

Choosing proper fluorescent dyes, proteins, and imaging techniques to study mitochondrial dynamics in mammalian cells.

Liu X, Yang L, Long Q, Weaver D, Hajnóczky G.

Biophys Rep. 2017;3(4):64-72. doi: 10.1007/s41048-017-0037-8. Epub 2017 Mar 24.

11.

ROS Control Mitochondrial Motility through p38 and the Motor Adaptor Miro/Trak.

Debattisti V, Gerencser AA, Saotome M, Das S, Hajnóczky G.

Cell Rep. 2017 Nov 7;21(6):1667-1680. doi: 10.1016/j.celrep.2017.10.060.

12.

Mitochondrial Nanotunnels.

Vincent AE, Turnbull DM, Eisner V, Hajnóczky G, Picard M.

Trends Cell Biol. 2017 Nov;27(11):787-799. doi: 10.1016/j.tcb.2017.08.009. Epub 2017 Sep 19. Review.

13.

Intracellular Ca2+ Sensing: Its Role in Calcium Homeostasis and Signaling.

Bagur R, Hajnóczky G.

Mol Cell. 2017 Jun 15;66(6):780-788. doi: 10.1016/j.molcel.2017.05.028. Review.

14.

MSTO1 is a cytoplasmic pro-mitochondrial fusion protein, whose mutation induces myopathy and ataxia in humans.

Gal A, Balicza P, Weaver D, Naghdi S, Joseph SK, Várnai P, Gyuris T, Horváth A, Nagy L, Seifert EL, Molnar MJ, Hajnóczky G.

EMBO Mol Med. 2017 Jul;9(7):967-984. doi: 10.15252/emmm.201607058.

15.

Recessive mutations in MSTO1 cause mitochondrial dynamics impairment, leading to myopathy and ataxia.

Nasca A, Scotton C, Zaharieva I, Neri M, Selvatici R, Magnusson OT, Gal A, Weaver D, Rossi R, Armaroli A, Pane M, Phadke R, Sarkozy A, Muntoni F, Hughes I, Cecconi A, Hajnóczky G, Donati A, Mercuri E, Zeviani M, Ferlini A, Ghezzi D.

Hum Mutat. 2017 Aug;38(8):970-977. doi: 10.1002/humu.23262. Epub 2017 Jun 6.

16.

Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca2+ Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU.

Paillard M, Csordás G, Szanda G, Golenár T, Debattisti V, Bartok A, Wang N, Moffat C, Seifert EL, Spät A, Hajnóczky G.

Cell Rep. 2017 Mar 7;18(10):2291-2300. doi: 10.1016/j.celrep.2017.02.032.

17.

Increased mitochondrial nanotunneling activity, induced by calcium imbalance, affects intermitochondrial matrix exchanges.

Lavorato M, Iyer VR, Dewight W, Cupo RR, Debattisti V, Gomez L, De la Fuente S, Zhao YT, Valdivia HH, Hajnóczky G, Franzini-Armstrong C.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):E849-E858. doi: 10.1073/pnas.1617788113. Epub 2017 Jan 17.

18.

Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity.

Eisner V, Cupo RR, Gao E, Csordás G, Slovinsky WS, Paillard M, Cheng L, Ibetti J, Chen SR, Chuprun JK, Hoek JB, Koch WJ, Hajnóczky G.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):E859-E868. doi: 10.1073/pnas.1617288114. Epub 2017 Jan 17.

19.

Natural and Induced Mitochondrial Phosphate Carrier Loss: DIFFERENTIAL DEPENDENCE OF MITOCHONDRIAL METABOLISM AND DYNAMICS AND CELL SURVIVAL ON THE EXTENT OF DEPLETION.

Seifert EL, Gál A, Acoba MG, Li Q, Anderson-Pullinger L, Golenár T, Moffat C, Sondheimer N, Claypool SM, Hajnóczky G.

J Biol Chem. 2016 Dec 9;291(50):26126-26137. Epub 2016 Oct 25.

20.

Redox Nanodomains Are Induced by and Control Calcium Signaling at the ER-Mitochondrial Interface.

Booth DM, Enyedi B, Geiszt M, Várnai P, Hajnóczky G.

Mol Cell. 2016 Jul 21;63(2):240-248. doi: 10.1016/j.molcel.2016.05.040. Epub 2016 Jul 7.

21.

Subcellular ROS imaging methods: Relevance for the study of calcium signaling.

Booth DM, Joseph SK, Hajnóczky G.

Cell Calcium. 2016 Aug;60(2):65-73. doi: 10.1016/j.ceca.2016.05.001. Epub 2016 May 4. Review.

22.

VDAC2-specific cellular functions and the underlying structure.

Naghdi S, Hajnóczky G.

Biochim Biophys Acta. 2016 Oct;1863(10):2503-14. doi: 10.1016/j.bbamcr.2016.04.020. Epub 2016 Apr 23. Review.

23.

MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration.

Antony AN, Paillard M, Moffat C, Juskeviciute E, Correnti J, Bolon B, Rubin E, Csordás G, Seifert EL, Hoek JB, Hajnóczky G.

Nat Commun. 2016 Mar 9;7:10955. doi: 10.1038/ncomms10955.

24.

Motifs of VDAC2 required for mitochondrial Bak import and tBid-induced apoptosis.

Naghdi S, Várnai P, Hajnóczky G.

Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):E5590-9. doi: 10.1073/pnas.1510574112. Epub 2015 Sep 28.

25.

MCUR1 is an essential component of mitochondrial Ca(2+) uptake that regulates cellular metabolism.

Mallilankaraman K, Cárdenas C, Doonan PJ, Chandramoorthy HC, Irrinki KM, Golenár T, Csordás G, Madireddi P, Yang J, Müller M, Miller R, Kolesar JE, Molgó J, Kaufman B, Hajnóczky G, Foskett JK, Madesh M.

Nat Cell Biol. 2015 Jul;17(7):953. doi: 10.1038/ncb3202. No abstract available.

PMID:
26123113
26.

The mitochondrial phosphate carrier: Role in oxidative metabolism, calcium handling and mitochondrial disease.

Seifert EL, Ligeti E, Mayr JA, Sondheimer N, Hajnóczky G.

Biochem Biophys Res Commun. 2015 Aug 21;464(2):369-75. doi: 10.1016/j.bbrc.2015.06.031. Epub 2015 Jun 16. Review.

PMID:
26091567
27.

Trans-mitochondrial coordination of cristae at regulated membrane junctions.

Picard M, McManus MJ, Csordás G, Várnai P, Dorn GW 2nd, Williams D, Hajnóczky G, Wallace DC.

Nat Commun. 2015 Feb 17;6:6259. doi: 10.1038/ncomms7259.

28.

Mitochondrial Ca(2+) uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity.

Shimizu H, Schredelseker J, Huang J, Lu K, Naghdi S, Lu F, Franklin S, Fiji HD, Wang K, Zhu H, Tian C, Lin B, Nakano H, Ehrlich A, Nakai J, Stieg AZ, Gimzewski JK, Nakano A, Goldhaber JI, Vondriska TM, Hajnóczky G, Kwon O, Chen JN.

Elife. 2015 Jan 15;4. doi: 10.7554/eLife.04801.

29.

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Campanella M, Candi E, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, Di Daniele N, Dixit VM, Dynlacht BD, El-Deiry WS, Fimia GM, Flavell RA, Fulda S, Garrido C, Gougeon ML, Green DR, Gronemeyer H, Hajnoczky G, Hardwick JM, Hengartner MO, Ichijo H, Joseph B, Jost PJ, Kaufmann T, Kepp O, Klionsky DJ, Knight RA, Kumar S, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lugli E, Madeo F, Malorni W, Marine JC, Martin SJ, Martinou JC, Medema JP, Meier P, Melino S, Mizushima N, Moll U, Muñoz-Pinedo C, Nuñez G, Oberst A, Panaretakis T, Penninger JM, Peter ME, Piacentini M, Pinton P, Prehn JH, Puthalakath H, Rabinovich GA, Ravichandran KS, Rizzuto R, Rodrigues CM, Rubinsztein DC, Rudel T, Shi Y, Simon HU, Stockwell BR, Szabadkai G, Tait SW, Tang HL, Tavernarakis N, Tsujimoto Y, Vanden Berghe T, Vandenabeele P, Villunger A, Wagner EF, Walczak H, White E, Wood WG, Yuan J, Zakeri Z, Zhivotovsky B, Melino G, Kroemer G.

Cell Death Differ. 2015 Jan;22(1):58-73. doi: 10.1038/cdd.2014.137. Epub 2014 Sep 19. Review.

30.

Loss of Miro1-directed mitochondrial movement results in a novel murine model for neuron disease.

Nguyen TT, Oh SS, Weaver D, Lewandowska A, Maxfield D, Schuler MH, Smith NK, Macfarlane J, Saunders G, Palmer CA, Debattisti V, Koshiba T, Pulst S, Feldman EL, Hajnóczky G, Shaw JM.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):E3631-40. doi: 10.1073/pnas.1402449111. Epub 2014 Aug 18.

31.

Reliance of ER-mitochondrial calcium signaling on mitochondrial EF-hand Ca2+ binding proteins: Miros, MICUs, LETM1 and solute carriers.

Hajnóczky G, Booth D, Csordás G, Debattisti V, Golenár T, Naghdi S, Niknejad N, Paillard M, Seifert EL, Weaver D.

Curr Opin Cell Biol. 2014 Aug;29:133-41. doi: 10.1016/j.ceb.2014.06.002. Epub 2014 Jul 10. Review.

32.

Distribution and apoptotic function of outer membrane proteins depend on mitochondrial fusion.

Weaver D, Eisner V, Liu X, Várnai P, Hunyady L, Gross A, Hajnóczky G.

Mol Cell. 2014 Jun 5;54(5):870-8. doi: 10.1016/j.molcel.2014.03.048. Epub 2014 May 8.

33.

Mitochondrial fusion is frequent in skeletal muscle and supports excitation-contraction coupling.

Eisner V, Lenaers G, Hajnóczky G.

J Cell Biol. 2014 Apr 28;205(2):179-95. doi: 10.1083/jcb.201312066. Epub 2014 Apr 21.

34.

Isoform- and species-specific control of inositol 1,4,5-trisphosphate (IP3) receptors by reactive oxygen species.

Bánsághi S, Golenár T, Madesh M, Csordás G, RamachandraRao S, Sharma K, Yule DI, Joseph SK, Hajnóczky G.

J Biol Chem. 2014 Mar 21;289(12):8170-81. doi: 10.1074/jbc.M113.504159. Epub 2014 Jan 27.

35.

Interactions between sarco-endoplasmic reticulum and mitochondria in cardiac and skeletal muscle - pivotal roles in Ca²⁺ and reactive oxygen species signaling.

Eisner V, Csordás G, Hajnóczky G.

J Cell Sci. 2013 Jul 15;126(Pt 14):2965-78. doi: 10.1242/jcs.093609. Epub 2013 Jul 10. Review.

36.

MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca²⁺ uniporter.

Csordás G, Golenár T, Seifert EL, Kamer KJ, Sancak Y, Perocchi F, Moffat C, Weaver D, de la Fuente Perez S, Bogorad R, Koteliansky V, Adijanto J, Mootha VK, Hajnóczky G.

Cell Metab. 2013 Jun 4;17(6):976-87. doi: 10.1016/j.cmet.2013.04.020.

37.

MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism.

Mallilankaraman K, Cárdenas C, Doonan PJ, Chandramoorthy HC, Irrinki KM, Golenár T, Csordás G, Madireddi P, Yang J, Müller M, Miller R, Kolesar JE, Molgó J, Kaufman B, Hajnóczky G, Foskett JK, Madesh M.

Nat Cell Biol. 2012 Dec;14(12):1336-43. doi: 10.1038/ncb2622. Epub 2012 Nov 25. Erratum in: Nat Cell Biol. 2013 Jan;15(1):123. Nat Cell Biol. 2015 Jul;17(7):953.

38.

Switch from ER-mitochondrial to SR-mitochondrial calcium coupling during muscle differentiation.

Yi M, Weaver D, Eisner V, Várnai P, Hunyady L, Ma J, Csordás G, Hajnóczky G.

Cell Calcium. 2012 Nov;52(5):355-65. doi: 10.1016/j.ceca.2012.05.012. Epub 2012 Jul 10.

39.

Mitochondrial morphology and dynamics in hepatocytes from normal and ethanol-fed rats.

Das S, Hajnóczky N, Antony AN, Csordás G, Gaspers LD, Clemens DL, Hoek JB, Hajnóczky G.

Pflugers Arch. 2012 Jul;464(1):101-9. doi: 10.1007/s00424-012-1100-4. Epub 2012 Apr 19.

40.

Bid-induced mitochondrial membrane permeabilization waves propagated by local reactive oxygen species (ROS) signaling.

Garcia-Perez C, Roy SS, Naghdi S, Lin X, Davies E, Hajnóczky G.

Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4497-502. doi: 10.1073/pnas.1118244109. Epub 2012 Mar 5.

41.

Calcium transport across the inner mitochondrial membrane: molecular mechanisms and pharmacology.

Csordás G, Várnai P, Golenár T, Sheu SS, Hajnóczky G.

Mol Cell Endocrinol. 2012 Apr 28;353(1-2):109-13. doi: 10.1016/j.mce.2011.11.011. Epub 2011 Nov 22. Review.

42.

Alignment of sarcoplasmic reticulum-mitochondrial junctions with mitochondrial contact points.

García-Pérez C, Schneider TG, Hajnóczky G, Csordás G.

Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H1907-15. doi: 10.1152/ajpheart.00397.2011. Epub 2011 Aug 19.

43.

Altered fusion dynamics underlie unique morphological changes in mitochondria during hypoxia-reoxygenation stress.

Liu X, Hajnóczky G.

Cell Death Differ. 2011 Oct;18(10):1561-72. doi: 10.1038/cdd.2011.13. Epub 2011 Mar 4.

44.

Activation of the mitochondrial permeability transition pore modulates Ca2+ responses to physiological stimuli in adult neurons.

Barsukova A, Komarov A, Hajnóczky G, Bernardi P, Bourdette D, Forte M.

Eur J Neurosci. 2011 Mar;33(5):831-42. doi: 10.1111/j.1460-9568.2010.07576.x. Epub 2011 Jan 24.

45.

Calcium signalling: fishing out molecules of mitochondrial calcium transport.

Hajnóczky G, Csordás G.

Curr Biol. 2010 Oct 26;20(20):R888-91. doi: 10.1016/j.cub.2010.09.035.

46.

Imaging interorganelle contacts and local calcium dynamics at the ER-mitochondrial interface.

Csordás G, Várnai P, Golenár T, Roy S, Purkins G, Schneider TG, Balla T, Hajnóczky G.

Mol Cell. 2010 Jul 9;39(1):121-32. doi: 10.1016/j.molcel.2010.06.029.

47.

Biophysical properties of mitochondrial fusion events in pancreatic beta-cells and cardiac cells unravel potential control mechanisms of its selectivity.

Twig G, Liu X, Liesa M, Wikstrom JD, Molina AJ, Las G, Yaniv G, Hajnóczky G, Shirihai OS.

Am J Physiol Cell Physiol. 2010 Aug;299(2):C477-87. doi: 10.1152/ajpcell.00427.2009. Epub 2010 May 5.

48.

MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria.

Zaltsman Y, Shachnai L, Yivgi-Ohana N, Schwarz M, Maryanovich M, Houtkooper RH, Vaz FM, De Leonardis F, Fiermonte G, Palmieri F, Gillissen B, Daniel PT, Jimenez E, Walsh S, Koehler CM, Roy SS, Walter L, Hajnóczky G, Gross A.

Nat Cell Biol. 2010 Jun;12(6):553-562. doi: 10.1038/ncb2057. Epub 2010 May 2.

49.

VDAC2 is required for truncated BID-induced mitochondrial apoptosis by recruiting BAK to the mitochondria.

Roy SS, Ehrlich AM, Craigen WJ, Hajnóczky G.

EMBO Rep. 2009 Dec;10(12):1341-7. doi: 10.1038/embor.2009.219. Epub 2009 Oct 9.

50.

Mitochondrial 'kiss-and-run': interplay between mitochondrial motility and fusion-fission dynamics.

Liu X, Weaver D, Shirihai O, Hajnóczky G.

EMBO J. 2009 Oct 21;28(20):3074-89. doi: 10.1038/emboj.2009.255. Epub 2009 Sep 10.

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