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Items: 1 to 50 of 104

1.

Drivers of persistent infection: pathogen-induced extracellular vesicles.

Cipriano MJ, Hajduk SL.

Essays Biochem. 2018 May 15;62(2):135-147. doi: 10.1042/EBC20170083. Print 2018 May 15. Review.

PMID:
29666211
2.

Sending a message: extracellular vesicles of pathogenic protozoan parasites.

Szempruch AJ, Dennison L, Kieft R, Harrington JM, Hajduk SL.

Nat Rev Microbiol. 2016 Nov;14(11):669-675. doi: 10.1038/nrmicro.2016.110. Epub 2016 Sep 12. Review.

PMID:
27615028
3.

Extracellular Vesicles from Trypanosoma brucei Mediate Virulence Factor Transfer and Cause Host Anemia.

Szempruch AJ, Sykes SE, Kieft R, Dennison L, Becker AC, Gartrell A, Martin WJ, Nakayasu ES, Almeida IC, Hajduk SL, Harrington JM.

Cell. 2016 Jan 14;164(1-2):246-257. doi: 10.1016/j.cell.2015.11.051.

4.

Trypanosome Lytic Factor-1 Initiates Oxidation-stimulated Osmotic Lysis of Trypanosoma brucei brucei.

Greene AS, Hajduk SL.

J Biol Chem. 2016 Feb 5;291(6):3063-75. doi: 10.1074/jbc.M115.680371. Epub 2015 Dec 8.

5.

In vivo analysis of trypanosome mitochondrial RNA function by artificial site-specific RNA endonuclease-mediated knockdown.

Szempruch AJ, Choudhury R, Wang Z, Hajduk SL.

RNA. 2015 Oct;21(10):1781-9. doi: 10.1261/rna.052084.115. Epub 2015 Aug 11.

6.

A retained secretory signal peptide mediates high density lipoprotein (HDL) assembly and function of haptoglobin-related protein.

Harrington JM, Nishanova T, Pena SR, Hess M, Scelsi CL, Widener J, Hajduk SL.

J Biol Chem. 2014 Sep 5;289(36):24811-20. doi: 10.1074/jbc.M114.567578. Epub 2014 Jul 17.

7.

A single amino acid substitution in the group 1 Trypanosoma brucei gambiense haptoglobin-hemoglobin receptor abolishes TLF-1 binding.

DeJesus E, Kieft R, Albright B, Stephens NA, Hajduk SL.

PLoS Pathog. 2013;9(4):e1003317. doi: 10.1371/journal.ppat.1003317. Epub 2013 Apr 18.

8.

Individual variation in levels of haptoglobin-related protein in children from Gabon.

Imrie HJ, Fowkes FJ, Migot-Nabias F, Luty AJ, Deloron P, Hajduk SL, Day KP.

PLoS One. 2012;7(11):e49816. doi: 10.1371/journal.pone.0049816. Epub 2012 Nov 20.

9.

Dual functions of α-ketoglutarate dehydrogenase E2 in the Krebs cycle and mitochondrial DNA inheritance in Trypanosoma brucei.

Sykes SE, Hajduk SL.

Eukaryot Cell. 2013 Jan;12(1):78-90. doi: 10.1128/EC.00269-12. Epub 2012 Nov 2.

10.

Trypanosome resistance to human innate immunity: targeting Achilles' heel.

Stephens NA, Kieft R, Macleod A, Hajduk SL.

Trends Parasitol. 2012 Dec;28(12):539-45. doi: 10.1016/j.pt.2012.09.002. Epub 2012 Oct 8. Review.

11.

Haptoglobin-hemoglobin receptor independent killing of African trypanosomes by human serum and trypanosome lytic factors.

Bullard W, Kieft R, Capewell P, Veitch NJ, Macleod A, Hajduk SL.

Virulence. 2012 Jan-Feb;3(1):72-6. doi: 10.4161/viru.3.1.18295. Epub 2012 Jan 1.

12.

Role of expression site switching in the development of resistance to human Trypanosome Lytic Factor-1 in Trypanosoma brucei brucei.

Kieft R, Stephens NA, Capewell P, MacLeod A, Hajduk SL.

Mol Biochem Parasitol. 2012 May;183(1):8-14. doi: 10.1016/j.molbiopara.2011.12.004. Epub 2011 Dec 29.

13.

Late endosomal Rab7 regulates lysosomal trafficking of endocytic but not biosynthetic cargo in Trypanosoma brucei.

Silverman JS, Schwartz KJ, Hajduk SL, Bangs JD.

Mol Microbiol. 2011 Nov;82(3):664-78. doi: 10.1111/j.1365-2958.2011.07842.x. Epub 2011 Sep 30.

14.

Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by trypanolytic factor 1.

Capewell P, Veitch NJ, Turner CM, Raper J, Berriman M, Hajduk SL, MacLeod A.

PLoS Negl Trop Dis. 2011 Sep;5(9):e1287. doi: 10.1371/journal.pntd.0001287. Epub 2011 Sep 6.

15.

Endosomal localization of the serum resistance-associated protein in African trypanosomes confers human infectivity.

Stephens NA, Hajduk SL.

Eukaryot Cell. 2011 Aug;10(8):1023-33. doi: 10.1128/EC.05112-11. Epub 2011 Jun 24.

16.

The plasma membrane of bloodstream-form African trypanosomes confers susceptibility and specificity to killing by hydrophobic peptides.

Harrington JM, Widener J, Stephens N, Johnson T, Francia M, Capewell P, Macleod A, Hajduk SL.

J Biol Chem. 2010 Sep 10;285(37):28659-66. doi: 10.1074/jbc.M110.151886. Epub 2010 Jul 8.

17.

Membrane permeabilization by trypanosome lytic factor, a cytolytic human high density lipoprotein.

Harrington JM, Howell S, Hajduk SL.

J Biol Chem. 2009 May 15;284(20):13505-12. doi: 10.1074/jbc.M900151200. Epub 2009 Mar 26.

18.

Alternative RNA editing produces a novel protein involved in mitochondrial DNA maintenance in trypanosomes.

Ochsenreiter T, Anderson S, Wood ZA, Hajduk SL.

Mol Cell Biol. 2008 Sep;28(18):5595-604. doi: 10.1128/MCB.00637-08. Epub 2008 Jul 7.

19.

The LAMP-like protein p67 plays an essential role in the lysosome of African trypanosomes.

Peck RF, Shiflett AM, Schwartz KJ, McCann A, Hajduk SL, Bangs JD.

Mol Microbiol. 2008 May;68(4):933-46. doi: 10.1111/j.1365-2958.2008.06195.x.

20.

Alternative mRNA editing in trypanosomes is extensive and may contribute to mitochondrial protein diversity.

Ochsenreiter T, Cipriano M, Hajduk SL.

PLoS One. 2008 Feb 13;3(2):e1566. doi: 10.1371/journal.pone.0001566.

21.

RNA-editing-associated protein 1 null mutant reveals link to mitochondrial RNA stability.

Hans J, Hajduk SL, Madison-Antenucci S.

RNA. 2007 Jun;13(6):881-9. Epub 2007 Apr 6.

22.

African trypanosomes: intracellular trafficking of host defense molecules.

Shiflett AM, Faulkner SD, Cotlin LF, Widener J, Stephens N, Hajduk SL.

J Eukaryot Microbiol. 2007 Jan-Feb;54(1):18-21.

PMID:
17300512
23.

KISS: the kinetoplastid RNA editing sequence search tool.

Ochsenreiter T, Cipriano M, Hajduk SL.

RNA. 2007 Jan;13(1):1-4. Epub 2006 Nov 22.

24.
25.

In vitro generation of human high-density-lipoprotein-resistant Trypanosoma brucei brucei.

Faulkner SD, Oli MW, Kieft R, Cotlin L, Widener J, Shiflett A, Cipriano MJ, Pacocha SE, Birkeland SR, Hajduk SL, McArthur AG.

Eukaryot Cell. 2006 Aug;5(8):1276-86.

26.

Microbiology. Timing the sexual development of parasites.

Hajduk SL.

Science. 2006 Aug 4;313(5787):626-7. No abstract available.

PMID:
16888130
27.
28.
29.

Human high density lipoproteins are platforms for the assembly of multi-component innate immune complexes.

Shiflett AM, Bishop JR, Pahwa A, Hajduk SL.

J Biol Chem. 2005 Sep 23;280(38):32578-85. Epub 2005 Jul 26.

31.

Cis Editing in Trypanosoma brucei brucei as a Model for Understanding Guide-RNA Structural and Functional Requirements.

Golden DE, Hajduk SL.

Biol Bull. 2004 Oct;207(2):169. No abstract available.

PMID:
27690603
32.

Light and electron microscopical observations of the effects of high-density lipoprotein on growth of Plasmodium falciparum in vitro.

Imrie H, Ferguson DJ, Carter M, Drain J, Schiflett A, Hajduk SL, Day KP.

Parasitology. 2004 Jun;128(Pt 6):577-84.

PMID:
15206459
33.

RNA ligase; picking up the pieces.

Wood ZA, Sabatini RS, Hajduk SL.

Mol Cell. 2004 Feb 27;13(4):455-6. Review.

34.

A sequence motif within trypanosome precursor tRNAs influences abundance and mitochondrial localization.

Sherrer RL, Yermovsky-Kammerer AE, Hajduk SL.

Mol Cell Biol. 2003 Dec;23(24):9061-72.

35.

Trypanosoma brucei cytochrome c1 is imported into mitochondria along an unusual pathway.

Priest JW, Hajduk SL.

J Biol Chem. 2003 Apr 25;278(17):15084-94. Epub 2003 Feb 10.

36.

Editing machines: the complexities of trypanosome RNA editing.

Madison-Antenucci S, Grams J, Hajduk SL.

Cell. 2002 Feb 22;108(4):435-8. Review.

37.

A trypanosome mitochondrial RNA polymerase is required for transcription and replication.

Grams J, Morris JC, Drew ME, Wang Z, Englund PT, Hajduk SL.

J Biol Chem. 2002 May 10;277(19):16952-9. Epub 2002 Feb 21.

38.

No trypanosome lytic activity in the sera of mice producing human haptoglobin-related protein.

Hatada S, Seed JR, Barker C, Hajduk SL, Black S, Maeda N.

Mol Biochem Parasitol. 2002 Feb;119(2):291-4. No abstract available.

PMID:
11814582
39.

Insight into the mechanism of trypanosome lytic factor-1 killing of Trypanosoma brucei brucei.

Bishop JR, Shimamura M, Hajduk SL.

Mol Biochem Parasitol. 2001 Nov;118(1):33-40.

PMID:
11704271
40.

Activity of human trypanosome lytic factor in mice.

Barker C, Barbour KW, Berger FG, Hajduk SL.

Mol Biochem Parasitol. 2001 Oct;117(2):129-36.

PMID:
11606222
41.

The lysosomal targeting and intracellular metabolism of trypanosome lytic factor by Trypanosoma brucei brucei.

Shimamura M, Hager KM, Hajduk SL.

Mol Biochem Parasitol. 2001 Jul;115(2):227-37.

PMID:
11420109
42.

Haptoglobin-related protein mediates trypanosome lytic factor binding to trypanosomes.

Drain J, Bishop JR, Hajduk SL.

J Biol Chem. 2001 Aug 10;276(32):30254-60. Epub 2001 May 14.

43.
44.

Identification of candidate mitochondrial RNA editing ligases from Trypanosoma brucei.

McManus MT, Shimamura M, Grams J, Hajduk SL.

RNA. 2001 Feb;7(2):167-75.

45.
46.
47.

Trypanosoma brucei guide RNA poly(U) tail formation is stabilized by cognate mRNA.

McManus MT, Adler BK, Pollard VW, Hajduk SL.

Mol Cell Biol. 2000 Feb;20(3):883-91.

48.

Expression and localization of serum resistance associated protein in Trypanosoma brucei rhodesiense.

Milner JD, Hajduk SL.

Mol Biochem Parasitol. 1999 Nov 30;104(2):271-83.

PMID:
10593181
49.

In vitro import of a nuclearly encoded tRNA into the mitochondrion of Trypanosoma brucei.

Yermovsky-Kammerer AE, Hajduk SL.

Mol Cell Biol. 1999 Sep;19(9):6253-9.

50.

A nuclear encoded and mitochondrial imported dicistronic tRNA precursor in Trypanosoma brucei.

LeBlanc AJ, Yermovsky-Kammerer AE, Hajduk SL.

J Biol Chem. 1999 Jul 23;274(30):21071-7.

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