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Items: 1 to 50 of 260

1.

Mass Spectrometry Amyloid Typing Is Reproducible across Multiple Organ Sites.

Holub D, Flodrova P, Pika T, Flodr P, Hajduch M, Dzubak P.

Biomed Res Int. 2019 Jan 31;2019:3689091. doi: 10.1155/2019/3689091. eCollection 2019.

2.

Correction to "Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides".

Tokarenko A, Lišková B, Smoleń S, Táborská N, Tichý M, Gurská S, Perlíková P, Frydrych I, Tloušt'ová E, Znojek P, Mertlíková-Kaiserová H, Poštová Slavětínská L, Pohl R, Klepetářová B, Khalid NU, Wenren Y, Laposa RR, Džubák P, Hajdúch M, Hocek M.

J Med Chem. 2019 Feb 14;62(3):1698. doi: 10.1021/acs.jmedchem.9b00114. Epub 2019 Jan 25. No abstract available.

3.

MLPA is a practical and complementary alternative to CMA for diagnostic testing in patients with autism spectrum disorders and identifying new candidate CNVs associated with autism.

Capkova P, Srovnal J, Capkova Z, Staffova K, Becvarova V, Trkova M, Adamova K, Santava A, Curtisova V, Hajduch M, Prochazka M.

PeerJ. 2019 Jan 9;6:e6183. doi: 10.7717/peerj.6183. eCollection 2019.

4.

The absence of high-risk human papillomavirus in Czech non-small cell lung cancer cases.

Jaworek H, Koudelakova V, Slavkovsky R, Drabek J, Hajduch M.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2019 Jan 10. doi: 10.5507/bp.2018.079. [Epub ahead of print]

PMID:
30631209
5.

Bioavailability and structural study of 20-hydroxyecdysone complexes with cyclodextrins.

Temirgaziyev BS, Kučáková K, Baizhigit YA, Jurášek M, Džubák P, Hajdúch M, Dolenský B, Drašar PB, Tuleuov BI, Adekenov SM.

Steroids. 2019 Jul;147:37-41. doi: 10.1016/j.steroids.2018.11.007. Epub 2018 Nov 17.

PMID:
30458190
6.

Implantation and diagnostics of endometrial receptivity.

Dvořan M, Vodička J, Dostál J, Hajdůch M, Džubák P, Pešková M, Pilka R.

Ceska Gynekol. Fall 2018;83(4):291-298. Review.

PMID:
30441961
7.

Imaging of Pseudomonas aeruginosa infection with Ga-68 labelled pyoverdine for positron emission tomography.

Petrik M, Umlaufova E, Raclavsky V, Palyzova A, Havlicek V, Haas H, Novy Z, Dolezal D, Hajduch M, Decristoforo C.

Sci Rep. 2018 Oct 24;8(1):15698. doi: 10.1038/s41598-018-33895-w.

8.

Early and Non-invasive Diagnosis of Aspergillosis Revealed by Infection Kinetics Monitored in a Rat Model.

Skriba A, Pluhacek T, Palyzova A, Novy Z, Lemr K, Hajduch M, Petrik M, Havlicek V.

Front Microbiol. 2018 Oct 8;9:2356. doi: 10.3389/fmicb.2018.02356. eCollection 2018.

9.

Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides.

Tokarenko A, Lišková B, Smoleń S, Táborská N, Tichý M, Gurská S, Perlíková P, Frydrych I, Tloušt'ová E, Znojek P, Mertlíková-Kaiserová H, Poštová Slavětínská L, Pohl R, Klepetářová B, Khalid NU, Wenren Y, Laposa RR, Džubák P, Hajdúch M, Hocek M.

J Med Chem. 2018 Oct 25;61(20):9347-9359. doi: 10.1021/acs.jmedchem.8b01258. Epub 2018 Oct 16. Erratum in: J Med Chem. 2019 Feb 14;62(3):1698.

10.

Pentamethinium salts as ligands for cancer: Sulfated polysaccharide co-receptors as possible therapeutic target.

Bříza T, Králová J, Rimpelová S, Havlík M, Kaplánek R, Kejík Z, Martásek P, Mikula I, Džubák P, Hajdúch M, Ruml T, Král V.

Bioorg Chem. 2019 Feb;82:74-85. doi: 10.1016/j.bioorg.2018.02.011. Epub 2018 Feb 16.

PMID:
30273836
11.

A Head-to-Head Analytical Comparison of Cobas 4800 HPV, PapilloCheck HPV Screening, and LMNX Genotyping Kit HPV GP for Detection of Human Papillomavirus DNA in Cervical and Cervicovaginal Swabs.

Jaworek H, Koudelakova V, Drabek J, Vrbkova J, Zborilova B, Oborna I, Brezinova J, Marek R, Huml K, Vanek P, Hajduch M.

J Mol Diagn. 2018 Nov;20(6):849-858. doi: 10.1016/j.jmoldx.2018.07.004. Epub 2018 Aug 28.

PMID:
30165205
12.

Differential Regulation of Methylation-Regulating Enzymes by Senescent Stromal Cells Drives Colorectal Cancer Cell Response to DNA-Demethylating Epi-Drugs.

Agrawal K, Das V, Táborská N, Gurský J, Džubák P, Hajdúch M.

Stem Cells Int. 2018 Aug 12;2018:6013728. doi: 10.1155/2018/6013728. eCollection 2018.

13.

Genetic Markers in Triple-Negative Breast Cancer.

Sporikova Z, Koudelakova V, Trojanec R, Hajduch M.

Clin Breast Cancer. 2018 Oct;18(5):e841-e850. doi: 10.1016/j.clbc.2018.07.023. Epub 2018 Aug 4. Review.

14.

Sugar modified pyrimido[4,5-b]indole nucleosides: synthesis and antiviral activity.

Konč J, Tichý M, Pohl R, Hodek J, Džubák P, Hajdúch M, Hocek M.

Medchemcomm. 2017 Aug 25;8(9):1856-1862. doi: 10.1039/c7md00319f. eCollection 2017 Sep 1.

15.

Estradiol dimer inhibits tubulin polymerization and microtubule dynamics.

Jurášek M, Černohorská M, Řehulka J, Spiwok V, Sulimenko T, Dráberová E, Darmostuk M, Gurská S, Frydrych I, Buriánová R, Ruml T, Hajdúch M, Bartůněk P, Dráber P, Džubák P, Drašar PB, Sedlák D.

J Steroid Biochem Mol Biol. 2018 Oct;183:68-79. doi: 10.1016/j.jsbmb.2018.05.008. Epub 2018 May 24.

PMID:
29803726
16.

Proteomics study of silver nanoparticles on Caco-2 cells.

Gioria S, Urbán P, Hajduch M, Barboro P, Cabaleiro N, La Spina R, Chassaigne H.

Toxicol In Vitro. 2018 Aug;50:347-372. doi: 10.1016/j.tiv.2018.03.015. Epub 2018 Apr 4.

17.

Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence.

Mrazkova B, Dzijak R, Imrichova T, Kyjacova L, Barath P, Dzubak P, Holub D, Hajduch M, Nahacka Z, Andera L, Holicek P, Vasicova P, Sapega O, Bartek J, Hodny Z.

Aging (Albany NY). 2018 Mar 28;10(3):434-462. doi: 10.18632/aging.101404.

18.

IDH Mutation Analysis in Glioma Patients by CADMA Compared with SNaPshot Assay and two Immunohistochemical Methods.

Urbanovska I, Megova MH, Dwight Z, Kalita O, Uvirova M, Simova J, Tuckova L, Buzrla P, Palecek T, Hajduch M, Dvorackova J, Drabek J.

Pathol Oncol Res. 2019 Jul;25(3):971-978. doi: 10.1007/s12253-018-0413-9. Epub 2018 Mar 19.

PMID:
29556922
19.

Integrated physical map of bread wheat chromosome arm 7DS to facilitate gene cloning and comparative studies.

Tulpová Z, Luo MC, Toegelová H, Visendi P, Hayashi S, Vojta P, Paux E, Kilian A, Abrouk M, Bartoš J, Hajdúch M, Batley J, Edwards D, Doležel J, Šimková H.

N Biotechnol. 2019 Jan 25;48:12-19. doi: 10.1016/j.nbt.2018.03.003. Epub 2018 Mar 8.

PMID:
29526810
20.

Identification of Eukaryotic Translation Elongation Factor 1-α 1 Gamendazole-Binding Site for Binding of 3-Hydroxy-4(1 H)-quinolinones as Novel Ligands with Anticancer Activity.

Burglová K, Rylová G, Markos A, Prichystalova H, Soural M, Petracek M, Medvedikova M, Tejral G, Sopko B, Hradil P, Dzubak P, Hajduch M, Hlavac J.

J Med Chem. 2018 Apr 12;61(7):3027-3036. doi: 10.1021/acs.jmedchem.8b00078. Epub 2018 Mar 16.

PMID:
29498519
21.

Acute lymphoblastic leukemia in a child with Leri-Weill syndrome and complete SHOX gene deletion: A Case Report.

Volejnikova J, Zapletalova J, Jarosova M, Urbankova H, Petr V, Klaskova E, Horwitz MS, Hajduch M, Mihal V.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2018 Mar;162(1):65-70. doi: 10.5507/bp.2018.002. Epub 2018 Feb 21.

22.

Newly designed 11-gene panel reveals first case of hereditary amyloidosis captured by massive parallel sequencing.

Chyra Kufova Z, Sevcikova T, Januska J, Vojta P, Boday A, Vanickova P, Filipova J, Growkova K, Jelinek T, Hajduch M, Hajek R.

J Clin Pathol. 2018 Aug;71(8):687-694. doi: 10.1136/jclinpath-2017-204978. Epub 2018 Feb 17.

23.

Nucleosidic DNA demethylating epigenetic drugs - A comprehensive review from discovery to clinic.

Agrawal K, Das V, Vyas P, Hajdúch M.

Pharmacol Ther. 2018 Aug;188:45-79. doi: 10.1016/j.pharmthera.2018.02.006. Epub 2018 Feb 15. Review.

24.

Cardiac amyloidosis: from clinical suspicion to morphological diagnosis.

Flodrova P, Flodr P, Pika T, Vymetal J, Holub D, Dzubak P, Hajduch M, Scudla V.

Pathology. 2018 Apr;50(3):261-268. doi: 10.1016/j.pathol.2017.10.012. Epub 2018 Feb 12. Review.

PMID:
29448998
25.

[The effect of circulating tumor cells on the survival of patients with pancreatic cancer 5-year results].

Bébarová L, Skalický P, Srovnal J, Prokopová A, Zapletalová J, Hajdúch M, Loveček M.

Rozhl Chir. Winter 2018;97(2):94-98. Czech.

PMID:
29444581
26.

Triterpenic azines, a new class of compounds with selective cytotoxicity to leukemia cells CCRF-CEM.

Pokorny J, Krajcovicova S, Hajduch M, Holoubek M, Gurska S, Dzubak P, Volna T, Popa I, Urban M.

Future Med Chem. 2018 Mar 1;10(5):483-491. doi: 10.4155/fmc-2017-0171. Epub 2018 Feb 9.

PMID:
29424548
27.

A Synthetic Approach for the Rapid Preparation of BODIPY Conjugates and their use in Imaging of Cellular Drug Uptake and Distribution.

Krajcovicova S, Stankova J, Dzubak P, Hajduch M, Soural M, Urban M.

Chemistry. 2018 Apr 3;24(19):4957-4966. doi: 10.1002/chem.201706093. Epub 2018 Mar 12.

PMID:
29411907
28.

Peloruside A-Induced Cell Death in Hypoxia Is p53 Dependent in HCT116 Colorectal Cancer Cells.

Řehulka J, Annadurai N, Frydrych I, Džubák P, Miller JH, Hajdúch M, Das V.

J Nat Prod. 2018 Mar 23;81(3):634-640. doi: 10.1021/acs.jnatprod.7b00961. Epub 2018 Feb 5.

PMID:
29400463
29.

N-Benzyl Substitution of Polyhydroxypyrrolidines: The Way to Selective Inhibitors of Golgi α-Mannosidase II.

Šesták S, Bella M, Klunda T, Gurská S, Džubák P, Wöls F, Wilson IBH, Sladek V, Hajdúch M, Poláková M, Kóňa J.

ChemMedChem. 2018 Feb 20;13(4):373-383. doi: 10.1002/cmdc.201700607. Epub 2018 Feb 6.

30.

Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.

Skrott Z, Mistrik M, Andersen KK, Friis S, Majera D, Gursky J, Ozdian T, Bartkova J, Turi Z, Moudry P, Kraus M, Michalova M, Vaclavkova J, Dzubak P, Vrobel I, Pouckova P, Sedlacek J, Miklovicova A, Kutt A, Li J, Mattova J, Driessen C, Dou QP, Olsen J, Hajduch M, Cvek B, Deshaies RJ, Bartek J.

Nature. 2017 Dec 14;552(7684):194-199. doi: 10.1038/nature25016. Epub 2017 Dec 6.

31.

Isocitrate Dehydrogenase Mutations are Better Prognostic Marker than O6-methylguanine-DNA Methyltransferase Promoter Methylation in Glioblastomas - a Retrospective, Single-centre Molecular Genetics Study of Gliomas.

Houdova Megova M, Drábek J, Dwight Z, Trojanec R, Koudeláková V, Vrbková J, Kalita O, Mlcochova S, Rabcanova M, Hajdúch M.

Klin Onkol. Fall 2017;30(5):361-371. doi: 10.14735/amko2017361.

PMID:
29031038
32.

Synthesis and antiproliferative properties of new hydrophilic esters of triterpenic acids.

Eignerova B, Tichy M, Krasulova J, Kvasnica M, Rarova L, Christova R, Urban M, Bednarczyk-Cwynar B, Hajduch M, Sarek J.

Eur J Med Chem. 2017 Nov 10;140:403-420. doi: 10.1016/j.ejmech.2017.09.041. Epub 2017 Sep 21.

PMID:
28987603
33.

In Search of System-Wide Productivity Gains - The Role of Global Collaborations in Preclinical Translation.

Ussi AE, de Kort M, Coussens NP, Aittokallio T, Hajduch M.

Clin Transl Sci. 2017 Nov;10(6):423-425. doi: 10.1111/cts.12498. Epub 2017 Sep 19. No abstract available.

34.

Whole Exome Sequencing of Aberrant Plasma Cells in a Patient with Multiple Myeloma Minimal Residual Disease.

Zatopkova M, Filipová J, Jelínek T, Vojta P, Sevcikova T, Simicek M, Rihova L, Bezdekova R, Growkova K, Kufová Z, Smejkalová J, Hajdúch M, Pour L, Minárik J, Jungová A, Maisnar V, Kryukov F, Hájek R.

Klin Onkol. Summer 2017;30(Supplementum2):75-80. doi: 10.14735/amko20172S75.

PMID:
28903574
35.

Biomarkers in Immunoglobulin Light Chain Amyloidosis.

Kufová Z, Sevcikova T, Growkova K, Vojta P, Filipová J, Adam Z, Pour L, Penka M, Rysava R, Němec P, Brozova L, Vychytilova P, Jurczyszyn A, Grosicki S, Barchnicka A, Hajdúch M, Simicek M, Hájek R.

Klin Onkol. Summer 2017;30(Supplementum2):60-67. doi: 10.14735/amko20172S60.

PMID:
28903572
36.

Toll-Like Receptor 7/8 Ligand, S28463, Suppresses Ascaris suum-induced Allergic Asthma in Nonhuman Primates.

Camateros P, Kanagaratham C, Najdekr L, Holub D, Vrbkova J, Coté L, Fournier J, Gourdon J, Creery D, Olivenstein R, Kopriva F, Adam T, Friedecký D, Džubák P, Hajdúch M, Radzioch D.

Am J Respir Cell Mol Biol. 2018 Jan;58(1):55-65. doi: 10.1165/rcmb.2017-0184OC.

PMID:
28850259
37.

Fenretinide differentially modulates the levels of long- and very long-chain ceramides by downregulating Cers5 enzyme: evidence from bench to bedside.

Garić D, De Sanctis JB, Wojewodka G, Houle D, Cupri S, Abu-Arish A, Hanrahan JW, Hajduch M, Matouk E, Radzioch D.

J Mol Med (Berl). 2017 Oct;95(10):1053-1064. doi: 10.1007/s00109-017-1564-y. Epub 2017 Jul 10.

PMID:
28695226
38.

Microtubule affinity-regulating kinases are potential druggable targets for Alzheimer's disease.

Annadurai N, Agrawal K, Džubák P, Hajdúch M, Das V.

Cell Mol Life Sci. 2017 Nov;74(22):4159-4169. doi: 10.1007/s00018-017-2574-1. Epub 2017 Jun 20. Review.

PMID:
28634681
39.

YAP regulates cell mechanics by controlling focal adhesion assembly.

Nardone G, Oliver-De La Cruz J, Vrbsky J, Martini C, Pribyl J, Skládal P, Pešl M, Caluori G, Pagliari S, Martino F, Maceckova Z, Hajduch M, Sanz-Garcia A, Pugno NM, Stokin GB, Forte G.

Nat Commun. 2017 May 15;8:15321. doi: 10.1038/ncomms15321.

40.

Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells.

Ozdian T, Holub D, Maceckova Z, Varanasi L, Rylova G, Rehulka J, Vaclavkova J, Slavik H, Moudry P, Znojek P, Stankova J, de Sanctis JB, Hajduch M, Dzubak P.

J Proteomics. 2017 Jun 6;162:73-85. doi: 10.1016/j.jprot.2017.05.005. Epub 2017 May 3.

PMID:
28478306
41.

Bridging the translational innovation gap through good biomarker practice.

van Gool AJ, Bietrix F, Caldenhoven E, Zatloukal K, Scherer A, Litton JE, Meijer G, Blomberg N, Smith A, Mons B, Heringa J, Koot WJ, Smit MJ, Hajduch M, Rijnders T, Ussi A.

Nat Rev Drug Discov. 2017 Sep;16(9):587-588. doi: 10.1038/nrd.2017.72. Epub 2017 Apr 28. No abstract available.

PMID:
28450744
42.

Cellular effects of the microtubule-targeting agent peloruside A in hypoxia-conditioned colorectal carcinoma cells.

Řehulka J, Annadurai N, Frydrych I, Znojek P, Džubák P, Northcote P, Miller JH, Hajdúch M, Das V.

Biochim Biophys Acta Gen Subj. 2017 Jul;1861(7):1833-1843. doi: 10.1016/j.bbagen.2017.03.023. Epub 2017 Mar 31.

PMID:
28366502
43.

Evaporation-reducing Culture Condition Increases the Reproducibility of Multicellular Spheroid Formation in Microtiter Plates.

Das V, Fürst T, Gurská S, Džubák P, Hajdúch M.

J Vis Exp. 2017 Mar 7;(121). doi: 10.3791/55403.

44.

Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides.

Tichý M, Smoleń S, Tloušt'ová E, Pohl R, Oždian T, Hejtmánková K, Lišková B, Gurská S, Džubák P, Hajdúch M, Hocek M.

J Med Chem. 2017 Mar 23;60(6):2411-2424. doi: 10.1021/acs.jmedchem.6b01766. Epub 2017 Mar 3.

45.

[Tumor cells transfer between the patient and laboratory animal as a basic methodological approach to the study of cancerogenesis and identification of biomarkers].

Klos D, Stašek M, Loveček M, Skalický P, Vrba R, Aujeský R, Havlík R, Neoral Č, Varanashi L, Hajdúch M, Vrbková J, Džubák P.

Rozhl Chir. Winter 2016;95(12):432-438. Czech.

PMID:
28182438
46.

Cytotoxic conjugates of betulinic acid and substituted triazoles prepared by Huisgen Cycloaddition from 30-azidoderivatives.

Sidova V, Zoufaly P, Pokorny J, Dzubak P, Hajduch M, Popa I, Urban M.

PLoS One. 2017 Feb 3;12(2):e0171621. doi: 10.1371/journal.pone.0171621. eCollection 2017.

47.

The natural cytokinin 2OH3MeOBAR induces cell death by a mechanism that is different from that of the "classical" cytokinin ribosides.

Voller J, Béres T, Zatloukal M, Kaminski PA, Niemann P, Doležal K, Džubák P, Hajdúch M, Strnad M.

Phytochemistry. 2017 Apr;136:156-164. doi: 10.1016/j.phytochem.2017.01.004. Epub 2017 Jan 30.

PMID:
28153445
48.

Synthesis and Cytotoxic Activity of Triterpenoid Thiazoles Derived from Allobetulin, Methyl Betulonate, Methyl Oleanonate, and Oleanonic Acid.

Borkova L, Adamek R, Kalina P, Drašar P, Dzubak P, Gurska S, Rehulka J, Hajduch M, Urban M, Sarek J.

ChemMedChem. 2017 Mar 7;12(5):390-398. doi: 10.1002/cmdc.201600626. Epub 2017 Jan 27.

PMID:
28084676
49.

DNA damage, repair monitoring and epigenetic DNA methylation changes in seedlings of Chernobyl soybeans.

Georgieva M, Rashydov NM, Hajduch M.

DNA Repair (Amst). 2017 Feb;50:14-21. doi: 10.1016/j.dnarep.2016.12.002. Epub 2016 Dec 16.

PMID:
28017527
50.

Assessing opportunities for coordinated R&D in early cancer detection and management in Europe.

Ussi AE, Rebolj M, Thorat MA, Bietrix F, Fauvel AC, Hajdúch M, Hill C, Walker I, van Engeland M, Cuzick J, Meijer G.

Int J Cancer. 2017 Apr 1;140(7):1700-1701. doi: 10.1002/ijc.30564. Epub 2016 Dec 27. No abstract available.

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