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Items: 1 to 50 of 72

1.

FXR1 Is an IL-19-Responsive RNA-Binding Protein that Destabilizes Pro-inflammatory Transcripts in Vascular Smooth Muscle Cells.

Herman AB, Vrakas CN, Ray M, Kelemen SE, Sweredoski MJ, Moradian A, Haines DS, Autieri MV.

Cell Rep. 2018 Jul 31;24(5):1176-1189. doi: 10.1016/j.celrep.2018.07.002.

2.

JNK-associated Leucine Zipper Protein Functions as a Docking Platform for Polo-like Kinase 1 and Regulation of the Associating Transcription Factor Forkhead Box Protein K1.

Ramkumar P, Lee CM, Moradian A, Sweredoski MJ, Hess S, Sharrocks AD, Haines DS, Reddy EP.

J Biol Chem. 2015 Dec 4;290(49):29617-28. doi: 10.1074/jbc.M115.664649. Epub 2015 Oct 14.

3.

Oncogenic protein MTBP interacts with MYC to promote tumorigenesis.

Grieb BC, Gramling MW, Arrate MP, Chen X, Beauparlant SL, Haines DS, Xiao H, Eischen CM.

Cancer Res. 2014 Jul 1;74(13):3591-602. doi: 10.1158/0008-5472.CAN-13-2149. Epub 2014 May 1.

4.

Activation of p107 by fibroblast growth factor, which is essential for chondrocyte cell cycle exit, is mediated by the protein phosphatase 2A/B55α holoenzyme.

Kurimchak A, Haines DS, Garriga J, Wu S, De Luca F, Sweredoski MJ, Deshaies RJ, Hess S, Graña X.

Mol Cell Biol. 2013 Aug;33(16):3330-42. doi: 10.1128/MCB.00082-13. Epub 2013 Jun 17.

5.

Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking.

Haines DS, Lee JE, Beauparlant SL, Kyle DB, den Besten W, Sweredoski MJ, Graham RL, Hess S, Deshaies RJ.

Mol Cell Proteomics. 2012 Jun;11(6):M111.016444. doi: 10.1074/mcp.M111.016444. Epub 2012 Feb 14.

6.

Ubiquitin and cancer: new discussions for a new journal.

Diehl JA, Fuchs SY, Haines DS.

Genes Cancer. 2010 Jul;1(7):679-80. doi: 10.1177/1947601910383565. No abstract available.

8.

B55alpha PP2A holoenzymes modulate the phosphorylation status of the retinoblastoma-related protein p107 and its activation.

Jayadeva G, Kurimchak A, Garriga J, Sotillo E, Davis AJ, Haines DS, Mumby M, Graña X.

J Biol Chem. 2010 Sep 24;285(39):29863-73. doi: 10.1074/jbc.M110.162354. Epub 2010 Jul 27.

9.

A deficiency in Mdm2 binding protein inhibits Myc-induced B-cell proliferation and lymphomagenesis.

Odvody J, Vincent T, Arrate MP, Grieb B, Wang S, Garriga J, Lozano G, Iwakuma T, Haines DS, Eischen CM.

Oncogene. 2010 Jun 3;29(22):3287-96. doi: 10.1038/onc.2010.82. Epub 2010 Mar 22.

10.

Generation and characterization of novel monoclonal antibodies recognizing UBXD1.

Ramkumar P, Smith BA, Akinbamidele AC, Kapcia J, Beauparlant SL, Haines DS.

Hybridoma (Larchmt). 2009 Dec;28(6):459-62. doi: 10.1089/hyb.2009.0035.

PMID:
20025508
11.

Identification of lysines within membrane-anchored Mga2p120 that are targets of Rsp5p ubiquitination and mediate mobilization of tethered Mga2p90.

Bhattacharya S, Shcherbik N, Vasilescu J, Smith JC, Figeys D, Haines DS.

J Mol Biol. 2009 Jan 23;385(3):718-25. doi: 10.1016/j.jmb.2008.11.018. Epub 2008 Nov 24.

12.

Nedd4, a human ubiquitin ligase, affects actin cytoskeleton in yeast cells.

Stawiecka-Mirota M, Kamińska J, Urban-Grimal D, Haines DS, Zoładek T.

Exp Cell Res. 2008 Nov 1;314(18):3318-25. doi: 10.1016/j.yexcr.2008.08.017. Epub 2008 Sep 9.

PMID:
18804462
13.

Retraction for D. R. Zweitzig, N. Shcherbik, and D. S. Haines: AAA ATPase P97 and adaptor UBXD1 suppress MDM2 ubiquitination and degradation and promote constitutive P53 turnover.

Zweitzig DR, Shcherbik N, Haines DS.

Mol Biol Cell. 2008 Nov;19(11):5029. doi: 10.1091/mbc.E08-01-0067. Epub 2008 Sep 3. No abstract available.

14.

Agonist-promoted Lys63-linked polyubiquitination of the human kappa-opioid receptor is involved in receptor down-regulation.

Li JG, Haines DS, Liu-Chen LY.

Mol Pharmacol. 2008 Apr;73(4):1319-30. doi: 10.1124/mol.107.042846. Epub 2008 Jan 22.

15.

Systematic determination of ion score cutoffs based on calculated false positive rates: application for identifying ubiquitinated proteins by tandem mass spectrometry.

Vasilescu J, Smith JC, Zweitzig DR, Denis NJ, Haines DS, Figeys D.

J Mass Spectrom. 2008 Mar;43(3):296-304.

PMID:
17957819
16.

WW domains 2 and 3 of Rsp5p play overlapping roles in binding to the LPKY motif of Spt23p and Mga2p.

Bhattacharya S, Zoladek T, Haines DS.

Int J Biochem Cell Biol. 2008;40(1):147-57. Epub 2007 Jul 22.

19.

Screening marine fungi for inhibitors of the C4 plant enzyme pyruvate phosphate dikinase: unguinol as a potential novel herbicide candidate.

Motti CA, Bourne DG, Burnell JN, Doyle JR, Haines DS, Liptrot CH, Llewellyn LE, Ludke S, Muirhead A, Tapiolas DM.

Appl Environ Microbiol. 2007 Mar;73(6):1921-7. Epub 2007 Jan 12.

20.

The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells.

Vasilescu J, Zweitzig DR, Denis NJ, Smith JC, Ethier M, Haines DS, Figeys D.

J Proteome Res. 2007 Jan;6(1):298-305.

PMID:
17203973
21.

The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest.

Nagl NG Jr, Patsialou A, Haines DS, Dallas PB, Beck GR Jr, Moran E.

Cancer Res. 2005 Oct 15;65(20):9236-44.

22.

Translation of in vitro inhibition by marine natural products of the C4 acid cycle enzyme pyruvate P(i) dikinase to in vivo C4 plant tissue death.

Haines DS, Burnell JN, Doyle JR, Llewellyn LE, Motti CA, Tapiolas DM.

J Agric Food Chem. 2005 May 18;53(10):3856-62. Erratum in: J Agric Food Chem. 2005 Nov 30;53(24):9638.

PMID:
15884807
23.

A rapid screening method to detect specific inhibitors of pyruvate orthophosphate dikinase as leads for C4 plant-selective herbicides.

Doyle JR, Burnell JN, Haines DS, Llewellyn LE, Motti CA, Tapiolas DM.

J Biomol Screen. 2005 Feb;10(1):67-75.

PMID:
15695345
24.

A single PXY motif located within the carboxyl terminus of Spt23p and Mga2p mediates a physical and functional interaction with ubiquitin ligase Rsp5p.

Shcherbik N, Kee Y, Lyon N, Huibregtse JM, Haines DS.

J Biol Chem. 2004 Dec 17;279(51):53892-8. Epub 2004 Oct 5.

25.

Ub on the move.

Shcherbik N, Haines DS.

J Cell Biochem. 2004 Sep 1;93(1):11-9. Review.

PMID:
15352157
26.

Rsp5p is required for ER bound Mga2p120 polyubiquitination and release of the processed/tethered transactivator Mga2p90.

Shcherbik N, Zoladek T, Nickels JT, Haines DS.

Curr Biol. 2003 Jul 15;13(14):1227-33.

27.

CDK9 is constitutively expressed throughout the cell cycle, and its steady-state expression is independent of SKP2.

Garriga J, Bhattacharya S, Calbó J, Marshall RM, Truongcao M, Haines DS, Graña X.

Mol Cell Biol. 2003 Aug;23(15):5165-73.

28.

Kinetics of inhibition of sperm beta-acrosin activity by suramin.

Hermans JM, Haines DS, James PS, Jones R.

FEBS Lett. 2003 Jun 5;544(1-3):119-22.

29.

SKP2 associates with p130 and accelerates p130 ubiquitylation and degradation in human cells.

Bhattacharya S, Garriga J, Calbó J, Yong T, Haines DS, Graña X.

Oncogene. 2003 Apr 24;22(16):2443-51.

PMID:
12717421
30.

Stimulation of human DNA polymerase epsilon by MDM2.

Asahara H, Li Y, Fuss J, Haines DS, Vlatkovic N, Boyd MT, Linn S.

Nucleic Acids Res. 2003 May 1;31(9):2451-9.

31.

Functional analysis of the human orthologue of the RSP5-encoded ubiquitin protein ligase, hNedd4, in yeast.

Gajewska B, Shcherbik N, Oficjalska D, Haines DS, Zoładek T.

Curr Genet. 2003 Apr;43(1):1-10. Epub 2003 Feb 8.

PMID:
12684839
32.
33.
34.

Assignment of the MDM2 binding protein gene (MTBP) to human chromosome band 8q24 by in situ hybridization.

Boyd MT, Zimonjic DB, Popescu NC, Athwal R, Haines DS.

Cytogenet Cell Genet. 2000;90(1-2):64-5. No abstract available.

PMID:
11060448
35.

MDM2 interacts with the C-terminus of the catalytic subunit of DNA polymerase epsilon.

Vlatkovic N, Guerrera S, Li Y, Linn S, Haines DS, Boyd MT.

Nucleic Acids Res. 2000 Sep 15;28(18):3581-6.

36.

A novel cellular protein (MTBP) binds to MDM2 and induces a G1 arrest that is suppressed by MDM2.

Boyd MT, Vlatkovic N, Haines DS.

J Biol Chem. 2000 Oct 13;275(41):31883-90.

37.
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40.

mdm2-P2 transcript levels predict the functional activity of the p53 tumor suppressor in primary leukemic cells.

Bull EK, Chakrabarty S, Brodsky I, Haines DS.

Oncogene. 1998 Apr 30;16(17):2249-57.

41.

The mdm2 proto-oncogene.

Haines DS.

Leuk Lymphoma. 1997 Jul;26(3-4):227-38. Review.

PMID:
9322885
42.

Altered expression of p53 and mdm-2 proteins at diagnosis is associated with early treatment failure in childhood acute lymphoblastic leukemia.

Marks DI, Kurz BW, Link MP, Ng E, Shuster JJ, Lauer SJ, Carroll D, Brodsky I, Haines DS.

J Clin Oncol. 1997 Mar;15(3):1158-62.

PMID:
9060559
43.

Expression of 14-3-3 gamma in injured arteries and growth factor- and cytokine-stimulated human vascular smooth muscle cells.

Autieri MV, Haines DS, Romanic AM, Ohlstein EH.

Cell Growth Differ. 1996 Nov;7(11):1453-60.

44.

Analysis of p53 and mdm-2 expression in 18 patients with Sézary syndrome.

Marks DI, Vonderheid EC, Kurz BW, Bigler RD, Sinha K, Morgan DA, Sukman A, Nowell PC, Haines DS.

Br J Haematol. 1996 Mar;92(4):890-9.

PMID:
8616082
45.

High incidence of potential p53 inactivation in poor outcome childhood acute lymphoblastic leukemia at diagnosis.

Marks DI, Kurz BW, Link MP, Ng E, Shuster JJ, Lauer SJ, Brodsky I, Haines DS.

Blood. 1996 Feb 1;87(3):1155-61.

PMID:
8562942
46.

Enhanced translation: a novel mechanism of mdm2 oncogene overexpression identified in human tumor cells.

Landers JE, Haines DS, Strauss JF 3rd, George DL.

Oncogene. 1994 Sep;9(9):2745-50.

PMID:
8058341
47.

Physical and functional interaction between wild-type p53 and mdm2 proteins.

Haines DS, Landers JE, Engle LJ, George DL.

Mol Cell Biol. 1994 Feb;14(2):1171-8.

48.

Interleukin-1 alpha mediates an alternative pathway for the antiproliferative action of poly(I.C) on human endothelial cells.

Garfinkel S, Haines DS, Brown S, Wessendorf J, Gillespie DH, Maciag T.

J Biol Chem. 1992 Dec 5;267(34):24375-8.

49.

Cellular and enzymatic activities of a synthetic heteropolymer double-stranded RNA of defined size.

Haines DS, Suhadolnik RJ, Hubbell HR, Gillespie DH.

J Biol Chem. 1992 Sep 15;267(26):18315-9. Erratum in: J Biol Chem 1994 Jun 10;269(23):16518.

50.

RNA abundance measured by a lysate RNase protection assay.

Haines DS, Gillespie DH.

Biotechniques. 1992 May;12(5):736-41.

PMID:
1381196

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