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Items: 1 to 50 of 426

1.

Surface functionalization of gold nanoclusters with arginine: a trade-off between microtumor uptake and radiotherapy enhancement.

Broekgaarden M, Bulin AL, Porret E, Musnier B, Chovelon B, Ravelet C, Sancey L, Elleaume H, Hainaut P, Coll JL, Le Guével X.

Nanoscale. 2020 Apr 3;12(13):6959-6963. doi: 10.1039/d0nr01138j.

PMID:
32187249
2.

Extracellular vesicles from myelodysplastic mesenchymal stromal cells induce DNA damage and mutagenesis of hematopoietic stem cells through miRNA transfer.

Meunier M, Guttin A, Ancelet S, Laurin D, Zannoni J, Lefebvre C, Tondeur S, Persoons V, Pezet M, Pernet-Gallay K, Chuffart F, Rousseaux S, Testard Q, Thevenon J, Jouzier C, Deleuze JF, Laulagnier K, Sadoul R, Chatellard C, Hainaut P, Polack B, Cahn JY, Issartel JP, Park S.

Leukemia. 2020 Feb 12. doi: 10.1038/s41375-020-0738-8. [Epub ahead of print] No abstract available.

PMID:
32051530
3.

Expression of p53 N-terminal isoforms in B-cell precursor acute lymphoblastic leukemia and its correlation with clinicopathological profiles.

Oh L, Hainaut P, Blanchet S, Ariffin H.

BMC Cancer. 2020 Feb 10;20(1):110. doi: 10.1186/s12885-020-6599-8.

4.

Editorial: Dissecting the pathological bone marrow niche through single-cell omics and artificial intelligence.

Park S, Hainaut P.

Curr Opin Oncol. 2020 Mar;32(2):137-138. doi: 10.1097/CCO.0000000000000604. No abstract available.

PMID:
32022757
5.

Deciphering the Impact of Early-Life Exposures to Highly Variable Environmental Factors on Foetal and Child Health: Design of SEPAGES Couple-Child Cohort.

Lyon-Caen S, Siroux V, Lepeule J, Lorimier P, Hainaut P, Mossuz P, Quentin J, Supernant K, Meary D, Chaperot L, Bayat S, Cassee F, Valentino S, Couturier-Tarrade A, Rousseau-Ralliard D, Chavatte-Palmer P, Philippat C, Pin I, Slama R, Study Group TS.

Int J Environ Res Public Health. 2019 Oct 14;16(20). pii: E3888. doi: 10.3390/ijerph16203888.

6.

Cancer prevention and control: hepatocellular carcinoma.

Hainaut P, Amadou A, Gormally E.

Ecancermedicalscience. 2019 Jul 25;13:949. doi: 10.3332/ecancer.2019.949. eCollection 2019.

7.

A global view of hepatocellular carcinoma: trends, risk, prevention and management.

Yang JD, Hainaut P, Gores GJ, Amadou A, Plymoth A, Roberts LR.

Nat Rev Gastroenterol Hepatol. 2019 Oct;16(10):589-604. doi: 10.1038/s41575-019-0186-y. Epub 2019 Aug 22. Review.

8.

An Empirical Validation of the Within-subject Biospecimens Pooling Approach to Minimize Exposure Misclassification in Biomarker-based Studies.

Vernet C, Philippat C, Agier L, Calafat AM, Ye X, Lyon-Caen S, Hainaut P, Siroux V, Schisterman EF, Slama R.

Epidemiology. 2019 Sep;30(5):756-767. doi: 10.1097/EDE.0000000000001056.

PMID:
31373935
9.

LKB1 specifies neural crest cell fates through pyruvate-alanine cycling.

Radu AG, Torch S, Fauvelle F, Pernet-Gallay K, Lucas A, Blervaque R, Delmas V, Schlattner U, Lafanechère L, Hainaut P, Tricaud N, Pingault V, Bondurand N, Bardeesy N, Larue L, Thibert C, Billaud M.

Sci Adv. 2019 Jul 17;5(7):eaau5106. doi: 10.1126/sciadv.aau5106. eCollection 2019 Jul.

10.

[Dyspnea in a 64 year-old woman].

Pothen L, Yildiz H, Aydin S, Camboni A, Lambert M, Hainaut P, Ebbo M.

Rev Med Interne. 2020 Jan;41(1):58-61. doi: 10.1016/j.revmed.2019.06.009. Epub 2019 Jul 13. French. No abstract available.

PMID:
31311673
11.

Nephrotic syndrome without kidney injury revealing intravascular large B cell lymphoma.

Pothen L, Aydin S, Camboni A, Hainaut P.

BMJ Case Rep. 2019 Jun 12;12(6). pii: e229359. doi: 10.1136/bcr-2019-229359.

PMID:
31196971
12.

Pulmonary Edema: Consider an Unusual Suspect.

Jopart C, Hainaut P, Ghaye B.

J Belg Soc Radiol. 2019 May 15;103(1):33. doi: 10.5334/jbsr.1819. No abstract available.

13.

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome caused by first-line antituberculosis drugs: Two case reports and a review of the literature.

Coster A, Aerts O, Herman A, Marot L, Horst N, Kenyon C, Vlieghe E, Hainaut P, Baeck M.

Contact Dermatitis. 2019 Nov;81(5):325-331. doi: 10.1111/cod.13296. Epub 2019 May 22. Review.

PMID:
31021423
14.

Response to: Concern regarding classification of germlineTP53 variants as likely pathogenic.

de Andrade KC, Frone MN, Wegman-Ostrosky T, Khincha PP, Kim J, Amadou A, Santiago KM, Fortes FP, Lemonnier N, Mirabello L, Stewart DR, Hainaut P, Kowalski LP, Savage SA, Achatz MI.

Hum Mutat. 2019 Jun;40(6):832-833. doi: 10.1002/humu.23749. Epub 2019 Apr 18. No abstract available.

PMID:
30997946
15.

Cost-effectiveness of early cancer surveillance for patients with Li-Fraumeni syndrome.

Tak CR, Biltaji E, Kohlmann W, Maese L, Hainaut P, Villani A, Malkin D, Sherwin CMT, Brixner DI, Schiffman JD.

Pediatr Blood Cancer. 2019 May;66(5):e27629. doi: 10.1002/pbc.27629. Epub 2019 Feb 4.

PMID:
30719841
16.

p53, stem cell biology and childhood blastomas.

Oh L, Hafsi H, Hainaut P, Ariffin H.

Curr Opin Oncol. 2019 Mar;31(2):84-91. doi: 10.1097/CCO.0000000000000504. Review.

PMID:
30585860
17.

Variable population prevalence estimates of germline TP53 variants: A gnomAD-based analysis.

de Andrade KC, Frone MN, Wegman-Ostrosky T, Khincha PP, Kim J, Amadou A, Santiago KM, Fortes FP, Lemonnier N, Mirabello L, Stewart DR, Hainaut P, Kowalski LP, Savage SA, Achatz MI.

Hum Mutat. 2019 Jan;40(1):97-105. doi: 10.1002/humu.23673. Epub 2018 Nov 19.

18.

Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms.

Mazein A, Ostaszewski M, Kuperstein I, Watterson S, Le Novère N, Lefaudeux D, De Meulder B, Pellet J, Balaur I, Saqi M, Nogueira MM, He F, Parton A, Lemonnier N, Gawron P, Gebel S, Hainaut P, Ollert M, Dogrusoz U, Barillot E, Zinovyev A, Schneider R, Balling R, Auffray C.

NPJ Syst Biol Appl. 2018 Jun 2;4:21. doi: 10.1038/s41540-018-0059-y. eCollection 2018.

19.

Correction to: Design and rationale of the non-interventional, edoxaban treatment in routiNe clinical prActice in patients with venous ThromboEmbolism in Europe (ETNA-VTE-Europe) study.

Cohen AT, Ay C, Hainaut P, Décousus H, Hoffmann U, Gaine S, Coppens M, da Silva PM, Jimenez D, Amann-Vesti B, Brüggenjürgen B, Levy P, Bastida JL, Vicaut E, Laeis P, Fronk EM, Zierhut W, Malzer T, Bramlage P, Agnelli G; ETNA-VTE-Europe investigators.

Thromb J. 2018 May 31;16:18. doi: 10.1186/s12959-018-0173-5. eCollection 2018.

20.

Design and rationale of the non-interventional, edoxaban treatment in routiNe clinical prActice in patients with venous ThromboEmbolism in Europe (ETNA-VTE-Europe) study.

Cohen AT, Ay C, Hainaut P, Décousus H, Hoffmann U, Gaine S, Coppens M, da Silva PM, Castro DJ, Amann-Vesti B, Brüggenjürgen B, Levy P, Bastida JL, Vicaut E, Laeis P, Fronk EM, Zierhut W, Malzer T, Bramlage P, Agnelli G; ETNA-VTE-Europe investigators.

Thromb J. 2018 May 1;16:9. doi: 10.1186/s12959-018-0163-7. eCollection 2018. Erratum in: Thromb J. 2018 May 31;16:18.

21.

Pulmonary Tumor Microembolism: When the Pathologist Looks Further Than the Radiologist.

De Greef J, Hainaut P.

Am J Med. 2018 Aug;131(8):e323. doi: 10.1016/j.amjmed.2018.03.007. Epub 2018 Mar 27. No abstract available.

PMID:
29596785
22.

Combination of AKT inhibitor ARQ 092 and sorafenib potentiates inhibition of tumor progression in cirrhotic rat model of hepatocellular carcinoma.

Jilkova ZM, Kuyucu AZ, Kurma K, Ahmad Pour ST, Roth GS, Abbadessa G, Yu Y, Schwartz B, Sturm N, Marche PN, Hainaut P, Decaens T.

Oncotarget. 2018 Jan 23;9(13):11145-11158. doi: 10.18632/oncotarget.24298. eCollection 2018 Feb 16.

23.

ALK fusion variants detection by targeted RNA-next generation sequencing and clinical responses to crizotinib in ALK-positive non-small cell lung cancer.

McLeer-Florin A, Duruisseaux M, Pinsolle J, Dubourd S, Mondet J, Phillips Houlbracq M, Magnat N, Fauré J, Chatagnon A, de Fraipont F, Giaj Levra M, Toffart AC, Ferretti G, Hainaut P, Brambilla E, Moro-Sibilot D, Lantuejoul S.

Lung Cancer. 2018 Feb;116:15-24. doi: 10.1016/j.lungcan.2017.12.004. Epub 2017 Dec 8.

PMID:
29413046
24.
25.

Training the Next Generation of Biobankers: A Two-Year Master's Course in the Management of Biobanks.

Gormally E, Hardy I, Caboux E, di Donato JH, Hainaut P, Hofman P.

Biopreserv Biobank. 2017 Oct;15(5):438-450. doi: 10.1089/bio.2017.0002. Epub 2017 Sep 18.

PMID:
28922617
26.

Higher-than-expected population prevalence of potentially pathogenic germline TP53 variants in individuals unselected for cancer history.

de Andrade KC, Mirabello L, Stewart DR, Karlins E, Koster R, Wang M, Gapstur SM, Gaudet MM, Freedman ND, Landi MT, Lemonnier N, Hainaut P, Savage SA, Achatz MI.

Hum Mutat. 2017 Dec;38(12):1723-1730. doi: 10.1002/humu.23320. Epub 2017 Sep 21.

27.

Cancer Diagnostic and Predictive Biomarkers 2016.

Buonaguro FM, Pauza CD, Tornesello ML, Hainaut P, Franco R, Tommasino M.

Biomed Res Int. 2017;2017:7362721. doi: 10.1155/2017/7362721. Epub 2017 Jun 18. No abstract available.

28.

Young adult survivors of childhood acute lymphoblastic leukemia show evidence of chronic inflammation and cellular aging.

Ariffin H, Azanan MS, Abd Ghafar SS, Oh L, Lau KH, Thirunavakarasu T, Sedan A, Ibrahim K, Chan A, Chin TF, Liew FF, Jeyamogan S, Rosli ES, Baharudin R, Yap TY, Skinner R, Lum SH, Hainaut P.

Cancer. 2017 Nov 1;123(21):4207-4214. doi: 10.1002/cncr.30857. Epub 2017 Jun 27.

29.

Plasma Circulating Tumor DNA Levels for the Monitoring of Melanoma Patients: Landscape of Available Technologies and Clinical Applications.

Busser B, Lupo J, Sancey L, Mouret S, Faure P, Plumas J, Chaperot L, Leccia MT, Coll JL, Hurbin A, Hainaut P, Charles J.

Biomed Res Int. 2017;2017:5986129. doi: 10.1155/2017/5986129. Epub 2017 Apr 6. Review.

30.

Mutant p53 targeting by the low molecular weight compound STIMA-1.

Zache N, Lambert JMR, Rökaeus N, Shen J, Hainaut P, Bergman J, Wiman KG, Bykov VJN.

Mol Oncol. 2017 May;11(5):595. doi: 10.1002/1878-0261.12065. No abstract available.

31.

Pooled Analysis of the Prognostic and Predictive Effects of TP53 Comutation Status Combined With KRAS or EGFR Mutation in Early-Stage Resected Non-Small-Cell Lung Cancer in Four Trials of Adjuvant Chemotherapy.

Shepherd FA, Lacas B, Le Teuff G, Hainaut P, Jänne PA, Pignon JP, Le Chevalier T, Seymour L, Douillard JY, Graziano S, Brambilla E, Pirker R, Filipits M, Kratzke R, Soria JC, Tsao MS; LACE-Bio Collaborative Group.

J Clin Oncol. 2017 Jun 20;35(18):2018-2027. doi: 10.1200/JCO.2016.71.2893. Epub 2017 Apr 28.

32.

Targeted deep sequencing of plasma circulating cell-free DNA reveals Vimentin and Fibulin 1 as potential epigenetic biomarkers for hepatocellular carcinoma.

Holmila R, Sklias A, Muller DC, Degli Esposti D, Guilloreau P, Mckay J, Sangrajrang S, Srivatanakul P, Hainaut P, Merle P, Herceg Z, Nogueira da Costa A.

PLoS One. 2017 Mar 23;12(3):e0174265. doi: 10.1371/journal.pone.0174265. eCollection 2017.

33.

Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice.

Leroy B, Ballinger ML, Baran-Marszak F, Bond GL, Braithwaite A, Concin N, Donehower LA, El-Deiry WS, Fenaux P, Gaidano G, Langerød A, Hellstrom-Lindberg E, Iggo R, Lehmann-Che J, Mai PL, Malkin D, Moll UM, Myers JN, Nichols KE, Pospisilova S, Ashton-Prolla P, Rossi D, Savage SA, Strong LC, Tonin PN, Zeillinger R, Zenz T, Fraumeni JF Jr, Taschner PE, Hainaut P, Soussi T.

Cancer Res. 2017 Mar 15;77(6):1250-1260. doi: 10.1158/0008-5472.CAN-16-2179. Review.

34.

PD-L1 protein expression assessed by immunohistochemistry is neither prognostic nor predictive of benefit from adjuvant chemotherapy in resected non-small cell lung cancer.

Tsao MS, Le Teuff G, Shepherd FA, Landais C, Hainaut P, Filipits M, Pirker R, Le Chevalier T, Graziano S, Kratze R, Soria JC, Pignon JP, Seymour L, Brambilla E.

Ann Oncol. 2017 Apr 1;28(4):882-889. doi: 10.1093/annonc/mdx003.

35.

More chinks in the armor of cancer: potential for new therapies.

Hainaut P, Plymoth A.

Curr Opin Oncol. 2017 Jan;29(1):33-34. No abstract available.

PMID:
27875343
36.

Somatic TP53 Mutations in the Era of Genome Sequencing.

Hainaut P, Pfeifer GP.

Cold Spring Harb Perspect Med. 2016 Nov 1;6(11). pii: a026179. doi: 10.1101/cshperspect.a026179. Review.

37.

The Role of the p53 Protein in Stem-Cell Biology and Epigenetic Regulation.

Levine AJ, Puzio-Kuter AM, Chan CS, Hainaut P.

Cold Spring Harb Perspect Med. 2016 Sep 1;6(9). pii: a026153. doi: 10.1101/cshperspect.a026153. Review.

38.

Circulating Osteopontin and Prediction of Hepatocellular Carcinoma Development in a Large European Population.

Duarte-Salles T, Misra S, Stepien M, Plymoth A, Muller D, Overvad K, Olsen A, Tjønneland A, Baglietto L, Severi G, Boutron-Ruault MC, Turzanski-Fortner R, Kaaks R, Boeing H, Aleksandrova K, Trichopoulou A, Lagiou P, Bamia C, Pala V, Palli D, Mattiello A, Tumino R, Naccarati A, Bueno-de-Mesquita HB, Peeters PH, Weiderpass E, Quirós JR, Agudo A, Sánchez-Cantalejo E, Ardanaz E, Gavrila D, Dorronsoro M, Werner M, Hemmingsson O, Ohlsson B, Sjöberg K, Wareham NJ, Khaw KT, Bradbury KE, Gunter MJ, Cross AJ, Riboli E, Jenab M, Hainaut P, Beretta L.

Cancer Prev Res (Phila). 2016 Sep;9(9):758-65. doi: 10.1158/1940-6207.CAPR-15-0434. Epub 2016 Jun 23.

39.

Screening for germline BRCA1, BRCA2, TP53 and CHEK2 mutations in families at-risk for hereditary breast cancer identified in a population-based study from Southern Brazil.

Palmero EI, Alemar B, Schüler-Faccini L, Hainaut P, Moreira-Filho CA, Ewald IP, Santos PK, Ribeiro PL, Oliveira CB, Calvez-Kelm FL, Tavtigian S, Cossio SL, Giugliani R, Caleffi M, Ashton-Prolla P.

Genet Mol Biol. 2016 May 24;39(2):210-22. doi: 10.1590/1678-4685-GMB-2014-0363. Erratum in: Genet Mol Biol. 2017 Mar 16;:0.

40.

Venous thromboembolism associated with acute cytomegalovirus infection: epidemiology and predisposing conditions.

Yildiz H, Zech F, Hainaut P.

Acta Clin Belg. 2016 Aug;71(4):231-4. doi: 10.1080/17843286.2016.1177265. Epub 2016 May 3.

PMID:
27141959
41.

Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer.

Reynoird N, Mazur PK, Stellfeld T, Flores NM, Lofgren SM, Carlson SM, Brambilla E, Hainaut P, Kaznowska EB, Arrowsmith CH, Khatri P, Stresemann C, Gozani O, Sage J.

Genes Dev. 2016 Apr 1;30(7):772-85. doi: 10.1101/gad.275529.115. Epub 2016 Mar 17.

42.

Prognostic and Predictive Effect of TP53 Mutations in Patients with Non-Small Cell Lung Cancer from Adjuvant Cisplatin-Based Therapy Randomized Trials: A LACE-Bio Pooled Analysis.

Ma X, Le Teuff G, Lacas B, Tsao MS, Graziano S, Pignon JP, Douillard JY, Le Chevalier T, Seymour L, Filipits M, Pirker R, Jänne PA, Shepherd FA, Brambilla E, Soria JC, Hainaut P; LACE-Bio Collaborative Group.

J Thorac Oncol. 2016 Jun;11(6):850-61. doi: 10.1016/j.jtho.2016.02.002. Epub 2016 Feb 17.

43.

Rare germline variant (rs78378222) in the TP53 3' UTR: Evidence for a new mechanism of cancer predisposition in Li-Fraumeni syndrome.

Macedo GS, Araujo Vieira I, Brandalize AP, Giacomazzi J, Inez Palmero E, Volc S, Rodrigues Paixão-Côrtes V, Caleffi M, Silva Alves M, Achatz MI, Hainaut P, Ashton-Prolla P.

Cancer Genet. 2016 Mar;209(3):97-106. doi: 10.1016/j.cancergen.2015.12.012. Epub 2016 Jan 7.

PMID:
26823150
44.

Patterns of Benign and Malignant Lesions of the Thyroid in Two Wilayahs of Northeastern Algeria.

Guidoum M, Kherfi-Kadi H, Benharkat-Boughaba O, Djemaa-Bendjazia A, Keghouche S, Abedi-Ardekani B, Azzouz A, Kadi Y, Hainaut P, Bouslama Z.

J Cancer Epidemiol. 2015;2015:849416. doi: 10.1155/2015/849416. Epub 2015 Nov 22.

45.

The Evolution of Tumors in Mice and Humans with Germline p53 Mutations.

Levine AJ, Chan CS, Dudgeon C, Puzio-Kuter A, Hainaut P.

Cold Spring Harb Symp Quant Biol. 2015;80:139-45. doi: 10.1101/sqb.2015.80.027631. Epub 2015 Dec 7. Review.

PMID:
26642854
46.

Ancestry of the Brazilian TP53 c.1010G>A (p.Arg337His, R337H) Founder Mutation: Clues from Haplotyping of Short Tandem Repeats on Chromosome 17p.

Paskulin DD, Giacomazzi J, Achatz MI, Costa S, Reis RM, Hainaut P, dos Santos SE, Ashton-Prolla P.

PLoS One. 2015 Nov 30;10(11):e0143262. doi: 10.1371/journal.pone.0143262. eCollection 2015.

47.

Editorial: from cancer genotypes to phenotypes: a never-ending complexity.

Hainaut P, Plymoth A.

Curr Opin Oncol. 2016 Jan;28(1):50-1. doi: 10.1097/CCO.0000000000000256. No abstract available.

PMID:
26599294
48.

Cancer Diagnostic and Predictive Biomarkers 2015.

Buonaguro FM, Pauza CD, Tornesello ML, Hainaut P, Franco R.

Biomed Res Int. 2015;2015:235985. doi: 10.1155/2015/235985. Epub 2015 Oct 12. No abstract available.

49.

Dietary Carbohydrate, Glycemic Index, Glycemic Load, and Breast Cancer Risk Among Mexican Women.

Amadou A, Degoul J, Hainaut P, Chajes V, Biessy C, Torres Mejia G, Huybrechts I, Moreno Macia H, Ortega C, Angeles-Llerenas A, Romieu I.

Epidemiology. 2015 Nov;26(6):917-24. doi: 10.1097/EDE.0000000000000374.

PMID:
26340313
50.

Molecular characteristics of Hepatitis B and chronic liver disease in a cohort of HB carriers from Bamako, Mali.

Traoré F, Gormally E, Villar S, Friesen MD, Groopman JD, Vernet G, Diallo S, Hainaut P, Maiga MY.

BMC Infect Dis. 2015 Apr 11;15:180. doi: 10.1186/s12879-015-0916-x.

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