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Items: 1 to 50 of 80

1.

Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues.

Eraslan B, Wang D, Gusic M, Prokisch H, Hallström BM, Uhlén M, Asplund A, Pontén F, Wieland T, Hopf T, Hahne H, Kuster B, Gagneur J.

Mol Syst Biol. 2019 Feb 18;15(2):e8513. doi: 10.15252/msb.20188513.

2.

A deep proteome and transcriptome abundance atlas of 29 healthy human tissues.

Wang D, Eraslan B, Wieland T, Hallström B, Hopf T, Zolg DP, Zecha J, Asplund A, Li LH, Meng C, Frejno M, Schmidt T, Schnatbaum K, Wilhelm M, Ponten F, Uhlen M, Gagneur J, Hahne H, Kuster B.

Mol Syst Biol. 2019 Feb 18;15(2):e8503. doi: 10.15252/msb.20188503.

3.

Increased Pancreatic Protease Activity in Response to Antibiotics Impairs Gut Barrier and Triggers Colitis.

Yoon H, Schaubeck M, Lagkouvardos I, Blesl A, Heinzlmeir S, Hahne H, Clavel T, Panda S, Ludwig C, Kuster B, Manichanh C, Kump P, Haller D, Hörmannsperger G.

Cell Mol Gastroenterol Hepatol. 2018 May 29;6(3):370-388.e3. doi: 10.1016/j.jcmgh.2018.05.008. eCollection 2018.

4.

Mining the Human Tissue Proteome for Protein Citrullination.

Lee CY, Wang D, Wilhelm M, Zolg DP, Schmidt T, Schnatbaum K, Reimer U, Pontén F, Uhlén M, Hahne H, Kuster B.

Mol Cell Proteomics. 2018 Jul;17(7):1378-1391. doi: 10.1074/mcp.RA118.000696. Epub 2018 Apr 2.

PMID:
29610271
5.

Protease signaling through protease activated receptor 1 mediate nerve activation by mucosal supernatants from irritable bowel syndrome but not from ulcerative colitis patients.

Buhner S, Hahne H, Hartwig K, Li Q, Vignali S, Ostertag D, Meng C, Hörmannsperger G, Braak B, Pehl C, Frieling T, Barbara G, De Giorgio R, Demir IE, Ceyhan GO, Zeller F, Boeckxstaens G, Haller D, Kuster B, Schemann M.

PLoS One. 2018 Mar 12;13(3):e0193943. doi: 10.1371/journal.pone.0193943. eCollection 2018.

6.

The target landscape of clinical kinase drugs.

Klaeger S, Heinzlmeir S, Wilhelm M, Polzer H, Vick B, Koenig PA, Reinecke M, Ruprecht B, Petzoldt S, Meng C, Zecha J, Reiter K, Qiao H, Helm D, Koch H, Schoof M, Canevari G, Casale E, Depaolini SR, Feuchtinger A, Wu Z, Schmidt T, Rueckert L, Becker W, Huenges J, Garz AK, Gohlke BO, Zolg DP, Kayser G, Vooder T, Preissner R, Hahne H, Tõnisson N, Kramer K, Götze K, Bassermann F, Schlegl J, Ehrlich HC, Aiche S, Walch A, Greif PA, Schneider S, Felder ER, Ruland J, Médard G, Jeremias I, Spiekermann K, Kuster B.

Science. 2017 Dec 1;358(6367). pii: eaan4368. doi: 10.1126/science.aan4368.

7.

Quantitative Proteomics for the Comprehensive Analysis of Stress Responses of Lactobacillus paracasei subsp. paracasei F19.

Schott AS, Behr J, Geißler AJ, Kuster B, Hahne H, Vogel RF.

J Proteome Res. 2017 Oct 6;16(10):3816-3829. doi: 10.1021/acs.jproteome.7b00474. Epub 2017 Sep 18.

PMID:
28862000
8.

Wilhelm et al. reply.

Wilhelm M, Hahne H, Savitski M, Marx H, Lemeer S, Bantscheff M, Kuster B.

Nature. 2017 Jul 26;547(7664):E23. doi: 10.1038/nature22294. No abstract available.

PMID:
28748931
9.

Bacterial Cellulose Shifts Transcriptome and Proteome of Cultured Endothelial Cells Towards Native Differentiation.

Feil G, Horres R, Schulte J, Mack AF, Petzoldt S, Arnold C, Meng C, Jost L, Boxleitner J, Kiessling-Wolf N, Serbest E, Helm D, Kuster B, Hartmann I, Korff T, Hahne H.

Mol Cell Proteomics. 2017 Sep;16(9):1563-1577. doi: 10.1074/mcp.RA117.000001. Epub 2017 Jun 21.

10.

Annotation of the Domestic Pig Genome by Quantitative Proteogenomics.

Marx H, Hahne H, Ulbrich SE, Schnieke A, Rottmann O, Frishman D, Kuster B.

J Proteome Res. 2017 Aug 4;16(8):2887-2898. doi: 10.1021/acs.jproteome.7b00184. Epub 2017 Jun 29.

PMID:
28625053
11.

Hydrophilic Strong Anion Exchange (hSAX) Chromatography Enables Deep Fractionation of Tissue Proteomes.

Ruprecht B, Wang D, Chiozzi RZ, Li LH, Hahne H, Kuster B.

Methods Mol Biol. 2017;1550:69-82. doi: 10.1007/978-1-4939-6747-6_7.

PMID:
28188524
12.

Ethylene glycol improves electrospray ionization efficiency in bottom-up proteomics.

Yu P, Hahne H, Wilhelm M, Kuster B.

Anal Bioanal Chem. 2017 Feb;409(4):1049-1057. doi: 10.1007/s00216-016-0023-x. Epub 2016 Oct 20.

PMID:
27766361
13.

Semi-supervised Learning Predicts Approximately One Third of the Alternative Splicing Isoforms as Functional Proteins.

Hao Y, Colak R, Teyra J, Corbi-Verge C, Ignatchenko A, Hahne H, Wilhelm M, Kuster B, Braun P, Kaida D, Kislinger T, Kim PM.

Cell Rep. 2015 Jul 14;12(2):183-9. doi: 10.1016/j.celrep.2015.06.031. Epub 2015 Jul 2.

14.

A Scalable Approach for Protein False Discovery Rate Estimation in Large Proteomic Data Sets.

Savitski MM, Wilhelm M, Hahne H, Kuster B, Bantscheff M.

Mol Cell Proteomics. 2015 Sep;14(9):2394-404. doi: 10.1074/mcp.M114.046995. Epub 2015 May 17.

15.

Molecular mechanisms behind the antimicrobial activity of hop iso-α-acids in Lactobacillus brevis.

Schurr BC, Hahne H, Kuster B, Behr J, Vogel RF.

Food Microbiol. 2015 Apr;46:553-563. doi: 10.1016/j.fm.2014.09.017. Epub 2014 Oct 21.

PMID:
25475328
16.

Ion mobility tandem mass spectrometry enhances performance of bottom-up proteomics.

Helm D, Vissers JP, Hughes CJ, Hahne H, Ruprecht B, Pachl F, Grzyb A, Richardson K, Wildgoose J, Maier SK, Marx H, Wilhelm M, Becher I, Lemeer S, Bantscheff M, Langridge JI, Kuster B.

Mol Cell Proteomics. 2014 Dec;13(12):3709-15. doi: 10.1074/mcp.M114.041038. Epub 2014 Aug 8.

17.

Mass-spectrometry-based draft of the human proteome.

Wilhelm M, Schlegl J, Hahne H, Gholami AM, Lieberenz M, Savitski MM, Ziegler E, Butzmann L, Gessulat S, Marx H, Mathieson T, Lemeer S, Schnatbaum K, Reimer U, Wenschuh H, Mollenhauer M, Slotta-Huspenina J, Boese JH, Bantscheff M, Gerstmair A, Faerber F, Kuster B.

Nature. 2014 May 29;509(7502):582-7. doi: 10.1038/nature13319.

PMID:
24870543
18.

Phosphoramidates as novel activity-based probes for serine proteases.

Haedke UR, Frommel SC, Hansen F, Hahne H, Kuster B, Bogyo M, Verhelst SH.

Chembiochem. 2014 May 26;15(8):1106-10. doi: 10.1002/cbic.201400013. Epub 2014 May 9.

PMID:
24817682
19.

A hydrodynamically optimized nano-electrospray ionization source and vacuum interface.

Pauly M, Sroka M, Reiss J, Rinke G, Albarghash A, Vogelgesang R, Hahne H, Kuster B, Sesterhenn J, Kern K, Rauschenbach S.

Analyst. 2014 Apr 21;139(8):1856-67. doi: 10.1039/c3an01836a.

PMID:
24479126
20.

Modulation of vitamin d status and dietary calcium affects bone mineral density and mineral metabolism in göttingen minipigs.

Scholz-Ahrens KE, Glüer CC, Bronner F, Delling G, Açil Y, Hahne HJ, Hassenpflug J, Timm W, Schrezenmeir J.

ISRN Rheumatol. 2013 Aug 24;2013:460512. doi: 10.1155/2013/460512. eCollection 2013.

21.

High-fat diet alters gut microbiota physiology in mice.

Daniel H, Gholami AM, Berry D, Desmarchelier C, Hahne H, Loh G, Mondot S, Lepage P, Rothballer M, Walker A, Böhm C, Wenning M, Wagner M, Blaut M, Schmitt-Kopplin P, Kuster B, Haller D, Clavel T.

ISME J. 2014 Feb;8(2):295-308. doi: 10.1038/ismej.2013.155. Epub 2013 Sep 12.

22.

DMSO enhances electrospray response, boosting sensitivity of proteomic experiments.

Hahne H, Pachl F, Ruprecht B, Maier SK, Klaeger S, Helm D, Médard G, Wilm M, Lemeer S, Kuster B.

Nat Methods. 2013 Oct;10(10):989-91. doi: 10.1038/nmeth.2610. Epub 2013 Aug 25.

PMID:
23975139
23.

Global proteome analysis of the NCI-60 cell line panel.

Gholami AM, Hahne H, Wu Z, Auer FJ, Meng C, Wilhelm M, Kuster B.

Cell Rep. 2013 Aug 15;4(3):609-20. doi: 10.1016/j.celrep.2013.07.018. Epub 2013 Aug 8.

24.

Comprehensive identification of proteins from MALDI imaging.

Maier SK, Hahne H, Gholami AM, Balluff B, Meding S, Schoene C, Walch AK, Kuster B.

Mol Cell Proteomics. 2013 Oct;12(10):2901-10. doi: 10.1074/mcp.M113.027599. Epub 2013 Jun 19.

25.

Co-immunoprecipitation-based identification of putative BAX INHIBITOR-1-interacting proteins involved in cell death regulation and plant-powdery mildew interactions.

Weis C, Pfeilmeier S, Glawischnig E, Isono E, Pachl F, Hahne H, Kuster B, Eichmann R, Hückelhoven R.

Mol Plant Pathol. 2013 Oct;14(8):791-802. doi: 10.1111/mpp.12050. Epub 2013 Jun 19.

PMID:
23782494
26.

Proteome wide purification and identification of O-GlcNAc-modified proteins using click chemistry and mass spectrometry.

Hahne H, Sobotzki N, Nyberg T, Helm D, Borodkin VS, van Aalten DM, Agnew B, Kuster B.

J Proteome Res. 2013 Feb 1;12(2):927-36. doi: 10.1021/pr300967y. Epub 2013 Jan 18.

27.

A simple and effective cleavable linker for chemical proteomics applications.

Yang Y, Hahne H, Kuster B, Verhelst SH.

Mol Cell Proteomics. 2013 Jan;12(1):237-44. doi: 10.1074/mcp.M112.021014. Epub 2012 Oct 1.

28.

Discovery of O-GlcNAc-6-phosphate modified proteins in large-scale phosphoproteomics data.

Hahne H, Kuster B.

Mol Cell Proteomics. 2012 Oct;11(10):1063-9. Epub 2012 Jul 23.

29.

MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancer.

Grüner BM, Hahne H, Mazur PK, Trajkovic-Arsic M, Maier S, Esposito I, Kalideris E, Michalski CW, Kleeff J, Rauser S, Schmid RM, Küster B, Walch A, Siveke JT.

PLoS One. 2012;7(6):e39424. doi: 10.1371/journal.pone.0039424. Epub 2012 Jun 26.

30.

Software tools for MS-based quantitative proteomics: a brief overview.

Lemeer S, Hahne H, Pachl F, Kuster B.

Methods Mol Biol. 2012;893:489-99. doi: 10.1007/978-1-61779-885-6_29. Review.

PMID:
22665318
31.

Discovery of O-GlcNAc-modified proteins in published large-scale proteome data.

Hahne H, Gholami AM, Kuster B.

Mol Cell Proteomics. 2012 Oct;11(10):843-50. Epub 2012 Jun 1.

32.

Lactocepin secreted by Lactobacillus exerts anti-inflammatory effects by selectively degrading proinflammatory chemokines.

von Schillde MA, Hörmannsperger G, Weiher M, Alpert CA, Hahne H, Bäuerl C, van Huynegem K, Steidler L, Hrncir T, Pérez-Martínez G, Kuster B, Haller D.

Cell Host Microbe. 2012 Apr 19;11(4):387-96. doi: 10.1016/j.chom.2012.02.006.

33.

Carbonyl-reactive tandem mass tags for the proteome-wide quantification of N-linked glycans.

Hahne H, Neubert P, Kuhn K, Etienne C, Bomgarden R, Rogers JC, Kuster B.

Anal Chem. 2012 Apr 17;84(8):3716-24. doi: 10.1021/ac300197c. Epub 2012 Apr 4.

PMID:
22455665
34.

Combined proteomic and transcriptomic analysis of the response of Bacillus anthracis to oxidative stress.

Pohl S, Tu WY, Aldridge PD, Gillespie C, Hahne H, Mäder U, Read TD, Harwood CR.

Proteomics. 2011 Aug;11(15):3036-55. doi: 10.1002/pmic.201100085. Epub 2011 Jul 4.

PMID:
21726052
35.

Enterococcus faecalis metalloprotease compromises epithelial barrier and contributes to intestinal inflammation.

Steck N, Hoffmann M, Sava IG, Kim SC, Hahne H, Tonkonogy SL, Mair K, Krueger D, Pruteanu M, Shanahan F, Vogelmann R, Schemann M, Kuster B, Sartor RB, Haller D.

Gastroenterology. 2011 Sep;141(3):959-71. doi: 10.1053/j.gastro.2011.05.035. Epub 2011 May 26.

PMID:
21699778
36.

A guide through the computational analysis of isotope-labeled mass spectrometry-based quantitative proteomics data: an application study.

Albaum SP, Hahne H, Otto A, Haußmann U, Becher D, Poetsch A, Goesmann A, Nattkemper TW.

Proteome Sci. 2011 Jun 11;9:30. doi: 10.1186/1477-5956-9-30.

37.

A novel two-stage tandem mass spectrometry approach and scoring scheme for the identification of O-GlcNAc modified peptides.

Hahne H, Kuster B.

J Am Soc Mass Spectrom. 2011 May;22(5):931-42. doi: 10.1007/s13361-011-0107-y. Epub 2011 Mar 26.

PMID:
21472528
38.

Bacterial production and functional characterization of the Fab fragment of the murine IgG1/lambda monoclonal antibody cmHsp70.1, a reagent for tumour diagnostics.

Friedrich L, Stangl S, Hahne H, Küster B, Köhler P, Multhoff G, Skerra A.

Protein Eng Des Sel. 2010 Apr;23(4):161-8. doi: 10.1093/protein/gzp095. Epub 2010 Feb 1.

PMID:
20123884
39.

A comprehensive proteomics and transcriptomics analysis of Bacillus subtilis salt stress adaptation.

Hahne H, Mäder U, Otto A, Bonn F, Steil L, Bremer E, Hecker M, Becher D.

J Bacteriol. 2010 Feb;192(3):870-82. doi: 10.1128/JB.01106-09. Epub 2009 Nov 30.

40.

From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches.

Hahne H, Wolff S, Hecker M, Becher D.

Proteomics. 2008 Oct;8(19):4123-36. doi: 10.1002/pmic.200800258.

PMID:
18763711
41.

Complementary analysis of the vegetative membrane proteome of the human pathogen Staphylococcus aureus.

Wolff S, Hahne H, Hecker M, Becher D.

Mol Cell Proteomics. 2008 Aug;7(8):1460-8. doi: 10.1074/mcp.M700554-MCP200. Epub 2008 May 6.

42.

In-patient, short-term group psychotherapy - a therapeutic option for Bundeswehr soldiers?

Zimmermann P, Kröger N, Willmund G, Ströhle A, Heinz A, Hahne HH.

Psychosoc Med. 2008 Dec 19;5:Doc11.

43.

Glucocorticosteroid-induced osteoporosis in adult primiparous Göttingen miniature pigs: effects on bone mineral and mineral metabolism.

Scholz-Ahrens KE, Delling G, Stampa B, Helfenstein A, Hahne HJ, Açil Y, Timm W, Barkmann R, Hassenpflug J, Schrezenmeir J, Glüer CC.

Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E385-95. Epub 2007 Apr 24.

44.

The objective determination of compliance in treatment of adolescent idiopathic scoliosis with spinal orthoses.

Helfenstein A, Lankes M, Ohlert K, Varoga D, Hahne HJ, Ulrich HW, Hassenpflug J.

Spine (Phila Pa 1976). 2006 Feb 1;31(3):339-44.

PMID:
16449908
45.

Comparing ultrasound measurements of neonatal hips using the methods of Graf and Terjesen.

Falliner A, Schwinzer D, Hahne HJ, Hedderich J, Hassenpflug J.

J Bone Joint Surg Br. 2006 Jan;88(1):104-6.

PMID:
16365130
46.
47.

[Psychogenic Disorders in German soldiers during World War I and II].

Zimmermann P, Hahne HH, Biesold KH, Lanczik M.

Fortschr Neurol Psychiatr. 2005 Feb;73(2):91-101. Review. German.

PMID:
15685493
48.

A long-term follow-up study of high tibial osteotomy for medial compartment osteoarthrosis.

Wu LD, Hahne HJ, Hassenpflug T.

Chin J Traumatol. 2004 Dec;7(6):348-53.

PMID:
15566691
49.

The dimensional accuracy of preparation of femoral cavity in cementless total hip arthroplasty.

Wu LD, Hahne HJ, Hassenpflug J.

J Zhejiang Univ Sci. 2004 Oct;5(10):1270-8.

50.

Early age of onset in fatal familial insomnia. Two novel cases and review of the literature.

Harder A, Gregor A, Wirth T, Kreuz F, Schulz-Schaeffer WJ, Windl O, Plotkin M, Amthauer H, Neukirch K, Kretzschmar HA, Kuhlmann T, Braas R, Hahne HH, Jendroska K.

J Neurol. 2004 Jun;251(6):715-24.

PMID:
15311348

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