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Items: 1 to 50 of 688

1.

Synthesis of Artemisinin-Estrogen Hybrids Highly Active against HCMV, P. falciparum, and Cervical and Breast Cancer.

Fröhlich T, Kiss A, Wölfling J, Mernyák E, Kulmány ÁE, Minorics R, Zupkó I, Leidenberger M, Friedrich O, Kappes B, Hahn F, Marschall M, Schneider G, Tsogoeva SB.

ACS Med Chem Lett. 2018 Oct 19;9(11):1128-1133. doi: 10.1021/acsmedchemlett.8b00381. eCollection 2018 Nov 8.

PMID:
30429957
2.

CRISPR/Cas precision: do we need to worry about off-targeting in plants?

Hahn F, Nekrasov V.

Plant Cell Rep. 2018 Nov 13. doi: 10.1007/s00299-018-2355-9. [Epub ahead of print]

PMID:
30426198
3.

Site-selective metallation of dicarbene precursors.

Bente S, Kampert F, Tan TTY, Hahn FE.

Chem Commun (Camb). 2018 Nov 13;54(91):12887-12890. doi: 10.1039/c8cc08440h.

PMID:
30379174
4.

Homo- and Heteroligand Poly-NHC Metal Assemblies: Synthesis by Narcissistic and Social Self-Sorting.

Wang YS, Feng T, Wang YY, Hahn FE, Han YF.

Angew Chem Int Ed Engl. 2018 Oct 11. doi: 10.1002/anie.201810010. [Epub ahead of print]

PMID:
30306679
5.

Introduction: Carbene Chemistry.

Hahn FE.

Chem Rev. 2018 Oct 10;118(19):9455-9456. doi: 10.1021/acs.chemrev.8b00495. No abstract available.

PMID:
30301355
6.

Total Synthesis of Complex Biosynthetic Late-Stage Intermediates and Bioconversion by a Tailoring Enzyme from Jerangolid Biosynthesis.

Lindner F, Friedrich S, Hahn F.

J Org Chem. 2018 Oct 26. doi: 10.1021/acs.joc.8b02047. [Epub ahead of print]

PMID:
30284827
7.

Novel cytomegalovirus-inhibitory compounds of the class pyrrolopyridines show a complex pattern of target binding that suggests an unusual mechanism of antiviral activity.

Hahn F, Hutterer C, Henry C, Hamilton ST, Strojan H, Kraut A, Schulte U, Schütz M, Kohrt S, Wangen C, Pfizer J, Couté Y, Rawlinson WD, Strobl S, Marschall M.

Antiviral Res. 2018 Nov;159:84-94. doi: 10.1016/j.antiviral.2018.09.012. Epub 2018 Sep 27.

PMID:
30268914
8.

Seasonal variation of BMI at admission in German adolescents with anorexia nervosa.

Kolar DR, Bühren K, Herpertz-Dahlmann B, Becker K, Egberts K, Ehrlich S, Fleischhaker C, von Gontard A, Hahn F, Huss M, Jaite C, Kaess M, Legenbauer T, Renner TJ, Roessner V, Schulze U, Sinzig J, Wessing I, Hebebrand J, Föcker M, Jenetzky E.

PLoS One. 2018 Sep 11;13(9):e0203844. doi: 10.1371/journal.pone.0203844. eCollection 2018.

9.

Supervision in der Weiterbildung zum Facharzt für Kinder- und Jugendpsychiatrie – welche Rolle spielt die dienstliche Abhängigkeit?

Schaff C, Flechtner HH, von Klitzing K, Martens R, Walter J, Hahn F, Schimansky G, Konrad Gemeinsame Kommission Psychotherapie der Drei Fachverbände Kjpp K.

Z Kinder Jugendpsychiatr Psychother. 2018 Sep;46(5):453. doi: 10.1024/1422-4917/a000618. German. No abstract available.

PMID:
30204070
10.

Preparation and Post-Assembly Modification of Metallosupramolecular Assemblies from Poly( N-Heterocyclic Carbene) Ligands.

Gan MM, Liu JQ, Zhang L, Wang YY, Hahn FE, Han YF.

Chem Rev. 2018 Oct 10;118(19):9587-9641. doi: 10.1021/acs.chemrev.8b00119. Epub 2018 Jul 5.

PMID:
29975040
11.

Preparation of polynuclear NHC complexes by post-synthetic modification of half-sandwich rhodium and iridium complexes bearing C-azolato ligands.

Aznarez F, Gao WX, Lin YJ, Hahn FE, Jin GX.

Dalton Trans. 2018 Jul 17;47(28):9442-9452. doi: 10.1039/c8dt02212g.

PMID:
29955744
12.

Complexes Bearing Protic N-Heterocyclic Carbene Ligands.

Kuwata S, Hahn FE.

Chem Rev. 2018 Oct 10;118(19):9642-9677. doi: 10.1021/acs.chemrev.8b00176. Epub 2018 Jun 25.

PMID:
29939023
13.

Synthesis of Thymoquinone-Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial Agents.

Fröhlich T, Reiter C, Saeed MEM, Hutterer C, Hahn F, Leidenberger M, Friedrich O, Kappes B, Marschall M, Efferth T, Tsogoeva SB.

ACS Med Chem Lett. 2017 Dec 21;9(6):534-539. doi: 10.1021/acsmedchemlett.7b00412. eCollection 2018 Jun 14.

PMID:
29937978
14.

Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin.

Çapcı Karagöz A, Reiter C, Seo EJ, Gruber L, Hahn F, Leidenberger M, Klein V, Hampel F, Friedrich O, Marschall M, Kappes B, Efferth T, Tsogoeva SB.

Bioorg Med Chem. 2018 Jul 23;26(12):3610-3618. doi: 10.1016/j.bmc.2018.05.041. Epub 2018 May 24.

PMID:
29887512
15.

Homology-Directed Repair of a Defective Glabrous Gene in Arabidopsis With Cas9-Based Gene Targeting.

Hahn F, Eisenhut M, Mantegazza O, Weber APM.

Front Plant Sci. 2018 Apr 5;9:424. doi: 10.3389/fpls.2018.00424. eCollection 2018.

16.

Synthesis of Artemisinin-Derived Dimers, Trimers and Dendrimers: Investigation of Their Antimalarial and Antiviral Activities Including Putative Mechanisms of Action.

Fröhlich T, Hahn F, Belmudes L, Leidenberger M, Friedrich O, Kappes B, Couté Y, Marschall M, Tsogoeva SB.

Chemistry. 2018 Jun 7;24(32):8103-8113. doi: 10.1002/chem.201800729. Epub 2018 May 14.

PMID:
29570874
17.

An Unusual Fatty Acyl:Adenylate Ligase (FAAL)-Acyl Carrier Protein (ACP) Didomain in Ambruticin Biosynthesis.

Hemmerling F, Lebe KE, Wunderlich J, Hahn F.

Chembiochem. 2018 May 18;19(10):1006-1011. doi: 10.1002/cbic.201800084. Epub 2018 Apr 18.

PMID:
29517170
18.

Artesunate-derived monomeric, dimeric and trimeric experimental drugs - Their unique mechanistic basis and pronounced antiherpesviral activity.

Hahn F, Fröhlich T, Frank T, Bertzbach LD, Kohrt S, Kaufer BB, Stamminger T, Tsogoeva SB, Marschall M.

Antiviral Res. 2018 Apr;152:104-110. doi: 10.1016/j.antiviral.2018.02.013. Epub 2018 Feb 16.

PMID:
29458133
19.

Template Synthesis of Three-Dimensional Hexakisimidazolium Cages.

Sun LY, Sinha N, Yan T, Wang YS, Tan TTY, Yu L, Han YF, Hahn FE.

Angew Chem Int Ed Engl. 2018 Apr 23;57(18):5161-5165. doi: 10.1002/anie.201713240. Epub 2018 Mar 24.

PMID:
29394472
20.

Host-guest capability of a three-dimensional heterometallic macrocycle.

Fan QJ, Lin YJ, Hahn FE, Jin GX.

Dalton Trans. 2018 Feb 13;47(7):2240-2246. doi: 10.1039/c7dt04453d.

PMID:
29363692
21.

Imidazole-stabilized, electron-deficient boron cations.

Sato K, Tan TTY, Schäfers F, Hahn FE, Stephan DW.

Dalton Trans. 2017 Dec 21;46(47):16404-16407. doi: 10.1039/c7dt04030j. Epub 2017 Nov 15.

PMID:
29138766
22.

Insights into the Dual Activity of a Bifunctional Dehydratase-Cyclase Domain.

Sung KH, Berkhan G, Hollmann T, Wagner L, Blankenfeldt W, Hahn F.

Angew Chem Int Ed Engl. 2018 Jan 2;57(1):343-347. doi: 10.1002/anie.201707774. Epub 2017 Dec 6.

PMID:
29084363
23.

Metallosupramolecular Architectures Obtained from Poly-N-heterocyclic Carbene Ligands.

Sinha N, Hahn FE.

Acc Chem Res. 2017 Sep 19;50(9):2167-2184. doi: 10.1021/acs.accounts.7b00158. Epub 2017 Aug 25.

PMID:
28841284
24.

[The inpatient treatment of patients with anorexia nervosa in German clinics].

Föcker M, Heidemann-Eggert E, Antony G, Becker K, Egberts K, Ehrlich S, Fleischhaker C, Hahn F, Jaite C, Kaess M, M E Schulze U, Sinzig J, Wagner C, Legenbauer T, Renner T, Wessing I, Herpertz-Dahlmann B, Hebebrand J, Bühren K.

Z Kinder Jugendpsychiatr Psychother. 2017 Sep;45(5):381-390. doi: 10.1024/1422-4917/a000545. Epub 2017 Aug 21. German.

PMID:
28825877
25.

First Sociodemographic, Pretreatment and Clinical Data from a German Web-Based Registry for Child and Adolescent Anorexia Nervosa.

Bühren K, Herpertz-Dahlmann B, Dempfle A, Becker K, Egberts KM, Ehrlich S, Fleischhaker C, von Gontard A, Hahn F, Jaite C, Kaess M, Legenbauer T, Renner TJ, Schrötter E, Schulze U, Sinzig J, Antony G, Hebebrand J, Föcker M.

Z Kinder Jugendpsychiatr Psychother. 2017 Sep;45(5):393-400. doi: 10.1024/1422-4917/a000544. Epub 2017 Aug 21.

26.

Diagnostic performance and reproducibility of T2w based and diffusion weighted imaging (DWI) based PI-RADSv2 lexicon descriptors for prostate MRI.

Benndorf M, Hahn F, Krönig M, Jilg CA, Krauss T, Langer M, Dovi-Akué P.

Eur J Radiol. 2017 Aug;93:9-15. doi: 10.1016/j.ejrad.2017.05.015. Epub 2017 May 18.

PMID:
28668436
27.

Unkorrigierte Pulmonalatresie mit Ventrikelseptumdefekt bei einer 31-jährigen Patientin: MRT-Untersuchung des Herzens zur Bestimmung der Anatomie und der Flüsse der aberranten Gefäße.

Hahn F, Russe MF, Langer M.

Rofo. 2017 Jun;189(6):547-548. doi: 10.1055/s-0043-101524. Epub 2017 Jun 7. German. No abstract available.

PMID:
28591888
28.

High-Fidelity, Narcissistic Self-Sorting in the Synthesis of Organometallic Assemblies from Poly-NHC Ligands.

Sinha N, Tan TTY, Peris E, Hahn FE.

Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7393-7397. doi: 10.1002/anie.201702637. Epub 2017 May 23.

PMID:
28544306
29.

Pyogenic Arthritis of the Fingers and the Wrist: Can We Shorten Antimicrobial Treatment Duration?

Meier R, Wirth T, Hahn F, Vögelin E, Sendi P.

Open Forum Infect Dis. 2017 Mar 25;4(2):ofx058. doi: 10.1093/ofid/ofx058. eCollection 2017 Spring.

30.

Correction: Regioselective C8-metalation of N-phosphine tethered adenine derivatives via C8-H activation.

Brackemeyer D, Schulte To Brinke C, Roelfes F, Hahn FE.

Dalton Trans. 2017 May 9;46(18):6129. doi: 10.1039/c7dt90068f.

PMID:
28443938
31.

Proteolysis of mature HIV-1 p6 Gag protein by the insulin-degrading enzyme (IDE) regulates virus replication in an Env-dependent manner.

Hahn F, Schmalen A, Setz C, Friedrich M, Schlößer S, Kölle J, Spranger R, Rauch P, Fraedrich K, Reif T, Karius-Fischer J, Balasubramanyam A, Henklein P, Fossen T, Schubert U.

PLoS One. 2017 Apr 7;12(4):e0174254. doi: 10.1371/journal.pone.0174254. eCollection 2017.

32.

Regioselective C8-metalation of N-phosphine tethered adenine derivatives via C8-H activation.

Brackemeyer D, Schulte To Brinke C, Roelfes F, Hahn FE.

Dalton Trans. 2017 Apr 5;46(14):4510-4513. doi: 10.1039/c7dt00682a.

PMID:
28304048
33.

An Efficient Visual Screen for CRISPR/Cas9 Activity in Arabidopsis thaliana.

Hahn F, Mantegazza O, Greiner A, Hegemann P, Eisenhut M, Weber AP.

Front Plant Sci. 2017 Jan 24;8:39. doi: 10.3389/fpls.2017.00039. eCollection 2017.

34.

Turn-On Fluorescence in Tetra-NHC Ligands by Rigidification through Metal Complexation: An Alternative to Aggregation-Induced Emission.

Sinha N, Stegemann L, Tan TT, Doltsinis NL, Strassert CA, Hahn FE.

Angew Chem Int Ed Engl. 2017 Mar 1;56(10):2785-2789. doi: 10.1002/anie.201610971. Epub 2017 Jan 27.

PMID:
28128484
35.

Small Molecule Activation with N,NR-MIC Platinum Complexes.

Jin H, Mück-Lichtenfeld C, Hepp A, Stephan DW, Hahn FE.

Chemistry. 2017 May 2;23(25):5943-5947. doi: 10.1002/chem.201700065. Epub 2017 Feb 6.

PMID:
28084055
36.

Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue.

Snowden E, Porter W, Hahn F, Ferguson M, Tong F, Parker JS, Middlebrook A, Ghanekar S, Dillmore WS, Blaesius R.

Mol Cancer Res. 2017 Apr;15(4):429-438. doi: 10.1158/1541-7786.MCR-16-0286-T. Epub 2016 Dec 30.

37.

Multiple behavioral factors are associated with occurrence of large, flat colorectal polyps.

Zhan T, Hahn F, Hielscher T, Bilge A, Grüger J, Weers J, Betge J, Gaiser T, Kähler G, Ebert MP, Belle S.

Int J Colorectal Dis. 2017 Apr;32(4):575-582. doi: 10.1007/s00384-016-2717-0. Epub 2016 Nov 28.

PMID:
27896421
38.

Characterisation of the Broadly-Specific O-Methyl-transferase JerF from the Late Stages of Jerangolid Biosynthesis.

Friedrich S, Hemmerling F, Lindner F, Warnke A, Wunderlich J, Berkhan G, Hahn F.

Molecules. 2016 Oct 29;21(11). pii: E1443.

39.

Single-Step Synthesis of Organometallic Molecular Squares from NR,NR',NR'',NR'''-Substituted Benzobiscarbenes.

Sinha N, Roelfes F, Hepp A, Hahn FE.

Chemistry. 2017 May 2;23(25):5939-5942. doi: 10.1002/chem.201604996. Epub 2016 Nov 10.

PMID:
27786392
40.

The Interplay between a Multifunctional Dehydratase Domain and a C-Methyltransferase Effects Olefin Shift in Ambruticin Biosynthesis.

Berkhan G, Merten C, Holec C, Hahn F.

Angew Chem Int Ed Engl. 2016 Oct 17;55(43):13589-13592. doi: 10.1002/anie.201607827. Epub 2016 Sep 27.

PMID:
27670141
41.

Biosynthesis of oxygen and nitrogen-containing heterocycles in polyketides.

Hemmerling F, Hahn F.

Beilstein J Org Chem. 2016 Jul 20;12:1512-50. doi: 10.3762/bjoc.12.148. eCollection 2016. Review.

42.

Modular "Click" Preparation of Bifunctional Polymeric Heterometallic Catalysts.

Wang W, Zhao L, Lv H, Zhang G, Xia C, Hahn FE, Li F.

Angew Chem Int Ed Engl. 2016 Jun 27;55(27):7665-70. doi: 10.1002/anie.201600999. Epub 2016 Mar 11.

PMID:
27331787
43.

Risk Factors for Local Recurrence of Large, Flat Colorectal Polyps after Endoscopic Mucosal Resection.

Zhan T, Hielscher T, Hahn F, Hauf C, Betge J, Ebert MP, Belle S.

Digestion. 2016;93(4):311-7. doi: 10.1159/000446364. Epub 2016 Jun 7.

PMID:
27271329
44.

Glutamic Acid Residues in HIV-1 p6 Regulate Virus Budding and Membrane Association of Gag.

Friedrich M, Setz C, Hahn F, Matthaei A, Fraedrich K, Rauch P, Henklein P, Traxdorf M, Fossen T, Schubert U.

Viruses. 2016 Apr 25;8(4):117. doi: 10.3390/v8040117.

45.

Synthesis of Complexes with Abnormal "Protic" N-Heterocyclic Carbenes.

Jin H, Tan TT, Hahn FE.

Angew Chem Int Ed Engl. 2015 Nov 9;54(46):13811-5. doi: 10.1002/anie.201507206. Epub 2015 Sep 25.

PMID:
26403225
46.

Reversible Formation and Transmetalation of Schiff-Base Complexes in Subcomponent Self-Assembly Reactions.

Lewing D, Koppetz H, Hahn FE.

Inorg Chem. 2015 Aug 3;54(15):7653-9. doi: 10.1021/acs.inorgchem.5b01334. Epub 2015 Jul 10.

PMID:
26161894
47.

Frequent co-occurrence of high-grade dysplasia in large flat colonic polyps (>20 mm) and synchronous polyps.

Zhan T, Hahn F, Hielscher T, Betge J, Kähler G, Ebert MP, Belle S.

BMC Gastroenterol. 2015 Jul 10;15:82. doi: 10.1186/s12876-015-0312-4.

48.

Synthesis of a new type of alkene metal complex using face-capping thione-alkene ligands.

Zhang L, Yan T, Han YF, Hahn FE, Jin GX.

Dalton Trans. 2015 May 21;44(19):8797-800. doi: 10.1039/c5dt01311a.

PMID:
25900251
49.

Diagnosing fractures: pain intensity and subjective functional impairment are unreliable markers for initial assessment of possible extremity fractures.

Tsitsilonis S, Lindner T, Haas NP, Hahn FM, Marnitz T, Wichlas F.

Eur J Emerg Med. 2016 Apr;23(2):155-8. doi: 10.1097/MEJ.0000000000000267.

PMID:
25886777
50.

Reversible photochemical modifications in dicarbene-derived metallacycles with coumarin pendants.

Han YF, Jin GX, Daniliuc CG, Hahn FE.

Angew Chem Int Ed Engl. 2015 Apr 13;54(16):4958-62. doi: 10.1002/anie.201411006. Epub 2015 Feb 25.

PMID:
25712481

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