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Biopsy-proven recurrent, acute, familial hypersensitivity pneumonitis: A case report and literature review.

Winstone T, Hague CJ, Churg A, Wright JL, Schellenberg R, Ryerson C.

Respir Med Case Rep. 2018 May 17;24:173-175. doi: 10.1016/j.rmcr.2018.05.007. eCollection 2018.


Oesophageal diameter is associated with severity but not progression of systemic sclerosis-associated interstitial lung disease.

Winstone TA, Hague CJ, Soon J, Sulaiman N, Murphy D, Leipsic J, Dunne JV, Wilcox PG, Ryerson CJ.

Respirology. 2018 Apr 11. doi: 10.1111/resp.13309. [Epub ahead of print]


Prospective evaluation of relationships between radiotherapy dose to masticatory apparatus and trismus.

Hague C, Beasley W, Garcez K, Lee LW, McPartlin A, McWilliam A, Ryder D, Sykes AJ, Thomson D, van Herk M, West C, Slevin NJ.

Acta Oncol. 2018 Aug;57(8):1038-1042. doi: 10.1080/0284186X.2018.1459047. Epub 2018 Apr 9.


Patient Involvement in the Design of a Phase III Trial Comparing Intensity-modulated Proton Therapy and Intensity-modulated Radiotherapy for Oropharyngeal Cancer.

Hague C, Foran B, Hall E, Guild S, Joseph O, Moule R, Nutting C, Parsons S, Prestwich R, Slevin N, West C, Thomson D.

Clin Oncol (R Coll Radiol). 2018 May;30(5):274-276. doi: 10.1016/j.clon.2018.01.018. Epub 2018 Feb 17. No abstract available.


Phenotyping COPD exacerbations using imaging and blood-based biomarkers.

Alotaibi NM, Chen V, Hollander Z, Hague CJ, Murphy DT, Leipsic JA, DeMarco ML, FitzGerald JM, McManus BM, Ng RT, Sin DD.

Int J Chron Obstruct Pulmon Dis. 2018 Jan 8;13:217-229. doi: 10.2147/COPD.S152484. eCollection 2018.


Dual energy computed tomography should be a first line preoperative localization imaging test for primary hyperparathyroidism patients.

Hiebert J, Hague C, Hou S, Wiseman SM.

Am J Surg. 2018 May;215(5):788-792. doi: 10.1016/j.amjsurg.2017.11.048. Epub 2018 Jan 5.


Coronary lumen volume to myocardial mass ratio in primary microvascular angina.

Grover R, Leipsic JA, Mooney J, Kueh SH, Ohana M, Nørgaard BL, Eftekhari A, Bax JJ, Murphy DT, Hague CJ, Seidman MA, Blanke P, Sedlak T, Sellers SL.

J Cardiovasc Comput Tomogr. 2017 Nov;11(6):423-428. doi: 10.1016/j.jcct.2017.09.015. Epub 2017 Sep 22.


Fractional flow reserve derived from coronary computed tomography angiography reclassification rate using value distal to lesion compared to lowest value.

Kueh SH, Mooney J, Ohana M, Kim U, Blanke P, Grover R, Sellers S, Ellis J, Murphy D, Hague C, Bax JJ, Nørgaard BL, Rabbat M, Leipsic JA.

J Cardiovasc Comput Tomogr. 2017 Nov;11(6):462-467. doi: 10.1016/j.jcct.2017.09.009. Epub 2017 Sep 21.


Total Airway Count on Computed Tomography and the Risk of Chronic Obstructive Pulmonary Disease Progression. Findings from a Population-based Study.

Kirby M, Tanabe N, Tan WC, Zhou G, Obeidat M, Hague CJ, Leipsic J, Bourbeau J, Sin DD, Hogg JC, Coxson HO; CanCOLD Collaborative Research Group; Canadian Respiratory Research Network; CanCOLD Collaborative Research Group, the Canadian Respiratory Research Network.

Am J Respir Crit Care Med. 2018 Jan 1;197(1):56-65. doi: 10.1164/rccm.201704-0692OC.


A Novel Method of Estimating Small Airway Disease Using Inspiratory-to-Expiratory Computed Tomography.

Kirby M, Yin Y, Tschirren J, Tan WC, Leipsic J, Hague CJ, Bourbeau J, Sin DD, Hogg JC, Coxson HO; CanCOLD Collaborative Research Group and the Canadian Respiratory Research Network.

Respiration. 2017;94(4):336-345. doi: 10.1159/000478865. Epub 2017 Aug 23.


Utility of Magnetic Resonance Imaging for the Diagnosis of Appendicitis During Pregnancy: A Canadian Experience.

Burns M, Hague CJ, Vos P, Tiwari P, Wiseman SM.

Can Assoc Radiol J. 2017 Nov;68(4):392-400. doi: 10.1016/j.carj.2017.02.004. Epub 2017 Jul 18.


Neuropsychological outcomes of pediatric demyelinating diseases: a review.

Tan A, Hague C, Greenberg BM, Harder L.

Child Neuropsychol. 2018 Jul;24(5):575-597. doi: 10.1080/09297049.2017.1339785. Epub 2017 Jun 21.


Cough is less common and less severe in systemic sclerosis-associated interstitial lung disease compared to other fibrotic interstitial lung diseases.

Cheng JZ, Wilcox PG, Glaspole I, Corte TJ, Murphy D, Hague CJ, Ryerson CJ.

Respirology. 2017 Nov;22(8):1592-1597. doi: 10.1111/resp.13084. Epub 2017 May 23.


Evaluation of endorectal ultrasound (ERUS) and MRI for prediction of circumferential resection margin (CRM) for rectal cancer.

Tsai C, Hague C, Xiong W, Raval M, Karimuddin A, Brown C, Phang PT.

Am J Surg. 2017 May;213(5):936-942. doi: 10.1016/j.amjsurg.2017.03.029. Epub 2017 Mar 27.


C-reactive protein and N-terminal prohormone brain natriuretic peptide as biomarkers in acute exacerbations of COPD leading to hospitalizations.

Chen YR, Chen V, Hollander Z, Leipsic JA, Hague CJ, DeMarco ML, FitzGerald JM, McManus BM, Ng RT, Sin DD.

PLoS One. 2017 Mar 22;12(3):e0174063. doi: 10.1371/journal.pone.0174063. eCollection 2017.


Testicular Vasculitis: A Sonographic and Pathologic Diagnosis.

Dixit A, Hague C, Bicknell S.

Case Rep Radiol. 2017;2017:8923621. doi: 10.1155/2017/8923621. Epub 2017 Jan 26.


Label-Free Dynamic Mass Redistribution Reveals Low-Density, Prosurvival α1B-Adrenergic Receptors in Human SW480 Colon Carcinoma Cells.

Harris DA, Park JM, Lee KS, Xu C, Stella N, Hague C.

J Pharmacol Exp Ther. 2017 May;361(2):219-228. doi: 10.1124/jpet.116.237255. Epub 2017 Feb 14.


Comparison of low-dose coronary artery calcium scoring using low tube current technique and hybrid iterative reconstruction vs. filtered back projection.

Sulaiman N, Soon J, Park JK, Naoum C, Kueh SH, Blanke P, Murphy D, Ellis J, Hague CJ, Leipsic J.

Clin Imaging. 2017 May - Jun;43:19-23. doi: 10.1016/j.clinimag.2017.01.017. Epub 2017 Feb 2.


Cellular Uptake and Delivery of Myeloperoxidase to Lysosomes Promote Lipofuscin Degradation and Lysosomal Stress in Retinal Cells.

Yogalingam G, Lee AR, Mackenzie DS, Maures TJ, Rafalko A, Prill H, Berguig GY, Hague C, Christianson T, Bell SM, LeBowitz JH.

J Biol Chem. 2017 Mar 10;292(10):4255-4265. doi: 10.1074/jbc.M116.739441. Epub 2017 Jan 23.


Emphysema Distribution and Diffusion Capacity Predict Emphysema Progression in Human Immunodeficiency Virus Infection.

Leung JM, Malagoli A, Santoro A, Besutti G, Ligabue G, Scaglioni R, Dai D, Hague C, Leipsic J, Sin DD, Man SP, Guaraldi G.

PLoS One. 2016 Nov 30;11(11):e0167247. doi: 10.1371/journal.pone.0167247. eCollection 2016.


Findings on Thoracic Computed Tomography Scans and Respiratory Outcomes in Persons with and without Chronic Obstructive Pulmonary Disease: A Population-Based Cohort Study.

Tan WC, Hague CJ, Leipsic J, Bourbeau J, Zheng L, Li PZ, Sin DD, Coxson HO, Kirby M, Hogg JC, Raju R, Road J, O'Donnell DE, Maltais F, Hernandez P, Cowie R, Chapman KR, Marciniuk DD, FitzGerald JM, Aaron SD; Canadian Respiratory Research Network and the CanCOLD Collaborative Research group.

PLoS One. 2016 Nov 18;11(11):e0166745. doi: 10.1371/journal.pone.0166745. eCollection 2016.


The bronchial epithelial cell bacterial microbiome and host response in patients infected with human immunodeficiency virus.

Sze MA, Xu S, Leung JM, Vucic EA, Shaipanich T, Moghadam A, Harris M, Guillemi S, Sinha S, Nislow C, Murphy D, Hague C, Leipsic J, Lam S, Lam W, Montaner JS, Sin DD, Man SF.

BMC Pulm Med. 2016 Nov 9;16(1):142.


The effect of a whole heart motion-correction algorithm on CT image quality and measurement reproducibility in Pre-TAVR aortic annulus evaluation.

Soon J, Sulaiman N, Park JK, Kueh SH, Naoum C, Murphy D, Ellis J, Hague CJ, Blanke P, Leipsic J.

J Cardiovasc Comput Tomogr. 2016 Sep-Oct;10(5):386-90. doi: 10.1016/j.jcct.2016.08.001. Epub 2016 Aug 21.


Aggressive angiomyxoma presenting as massive irreducible vaginal prolapse.

Larouche M, Hague CJ, Masoudi H, Geoffrion R.

Int Urogynecol J. 2016 Dec;27(12):1933-1934. Epub 2016 Aug 10. No abstract available.


Endogenous N-terminal Domain Cleavage Modulates α1D-Adrenergic Receptor Pharmacodynamics.

Kountz TS, Lee KS, Aggarwal-Howarth S, Curran E, Park JM, Harris DA, Stewart A, Hendrickson J, Camp ND, Wolf-Yadlin A, Wang EH, Scott JD, Hague C.

J Biol Chem. 2016 Aug 26;291(35):18210-21. doi: 10.1074/jbc.M116.729517. Epub 2016 Jul 5.


Clinical experience with radium-223 in the treatment of patients with advanced castrate-resistant prostate cancer and symptomatic bone metastases.

Hague C, Logue JP.

Ther Adv Urol. 2016 Jun;8(3):175-80. doi: 10.1177/1756287216629870. Epub 2016 Feb 25. Review.


The current utility of ultrasound in the diagnosis of acute appendicitis.

Lourenco P, Brown J, Leipsic J, Hague C.

Clin Imaging. 2016 Sep-Oct;40(5):944-8. doi: 10.1016/j.clinimag.2016.03.012. Epub 2016 Apr 2.


Current Views on Clinical Oncology Training from the 2015 Oncology Registrars' Forum Survey.

Kosmin M, Brown S, Hague C, Said J, Wells L, Wilson C.

Clin Oncol (R Coll Radiol). 2016 Sep;28(9):e121-5. doi: 10.1016/j.clon.2016.04.043. Epub 2016 May 12.


Implementation of a Longitudinal Introduction to Radiology Course During Internship Year Improves Diagnostic Radiology Residents' Academic and Clinical Skills: A Canadian Experience.

Darras KE, Worthington A, Russell D, Hou DJ, Forster BB, Hague CJ, Mar C, Chang SD.

Acad Radiol. 2016 Jul;23(7):848-60. doi: 10.1016/j.acra.2016.03.007. Epub 2016 May 10.


Rapid automatized naming (RAN) in children with ADHD: An ex-Gaussian analysis.

Ryan M, Jacobson LA, Hague C, Bellows A, Denckla MB, Mahone EM.

Child Neuropsychol. 2017 Jul;23(5):571-587. doi: 10.1080/09297049.2016.1172560. Epub 2016 Apr 24.


Development of a new categorization system for pesticides exposure to support harmonized reporting between EU Member States.

Settimi L, Orford R, Davanzo F, Hague C, Desel H, Pelclova D, Dragelyte G, Mathieu-Nolf M, Adams R, Duarte-Davidson R.

Environ Int. 2016 May;91:332-40. doi: 10.1016/j.envint.2016.02.034. Epub 2016 Mar 24.


Transthoracic Computed Tomography-Guided Lung Nodule Biopsy: Comparison of Core Needle and Fine Needle Aspiration Techniques.

Sangha BS, Hague CJ, Jessup J, O'Connor R, Mayo JR.

Can Assoc Radiol J. 2016 Aug;67(3):284-9. doi: 10.1016/j.carj.2015.10.005. Epub 2016 Mar 19.


Dual-energy computed tomography: a promising novel preoperative localization study for treatment of primary hyperparathyroidism.

Seyednejad N, Healy C, Tiwari P, Vos P, Sexsmith G, Melck A, Hague C, Wiseman SM.

Am J Surg. 2016 May;211(5):839-45. doi: 10.1016/j.amjsurg.2016.01.003. Epub 2016 Feb 26.


Comparison of image quality, and diagnostic interpretability of a new volumetric high temporal resolution scanner versus 64-slice MDCT.

Raju R, Cury RC, Precious B, Blanke P, Naoum C, Arepalli C, Batlle JC, Murphy D, Hague C, Leipsic JA.

Clin Imaging. 2016 Mar-Apr;40(2):205-11. doi: 10.1016/j.clinimag.2015.10.009. Epub 2015 Oct 27.


Mitral Annular Dimensions and Geometry in Patients With Functional Mitral Regurgitation and Mitral Valve Prolapse: Implications for Transcatheter Mitral Valve Implantation.

Naoum C, Leipsic J, Cheung A, Ye J, Bilbey N, Mak G, Berger A, Dvir D, Arepalli C, Grewal J, Muller D, Murphy D, Hague C, Piazza N, Webb J, Blanke P.

JACC Cardiovasc Imaging. 2016 Mar;9(3):269-80. doi: 10.1016/j.jcmg.2015.08.022. Epub 2016 Feb 17.


Dynamic mass redistribution reveals diverging importance of PDZ-ligands for G protein-coupled receptor pharmacodynamics.

Camp ND, Lee KS, Cherry A, Wacker-Mhyre JL, Kountz TS, Park JM, Harris DA, Estrada M, Stewart A, Stella N, Wolf-Yadlin A, Hague C.

Pharmacol Res. 2016 Mar;105:13-21. doi: 10.1016/j.phrs.2016.01.003. Epub 2016 Jan 7.


Individual protomers of a G protein-coupled receptor dimer integrate distinct functional modules.

Camp ND, Lee KS, Wacker-Mhyre JL, Kountz TS, Park JM, Harris DA, Estrada M, Stewart A, Wolf-Yadlin A, Hague C.

Cell Discov. 2015;1. pii: 15011. Epub 2015 Jun 16.


Safety and efficiency of outpatient versus emergency department-based coronary CT angiography for evaluation of patients with potential ischemic chest pain.

Scheuermeyer FX, Grunau B, Raju R, Choy S, Naoum C, Blanke P, Hague C, Heilbron B, Taylor C, Kalla D, Christenson J, Innes G, Hanakova M, Leipsic J.

J Cardiovasc Comput Tomogr. 2015 Nov-Dec;9(6):534-7. doi: 10.1016/j.jcct.2015.08.001. Epub 2015 Aug 17.


Characteristics of COPD in never-smokers and ever-smokers in the general population: results from the CanCOLD study.

Tan WC, Sin DD, Bourbeau J, Hernandez P, Chapman KR, Cowie R, FitzGerald JM, Marciniuk DD, Maltais F, Buist AS, Road J, Hogg JC, Kirby M, Coxson H, Hague C, Leipsic J, O'Donnell DE, Aaron SD; CanCOLD Collaborative Research Group.

Thorax. 2015 Sep;70(9):822-9. doi: 10.1136/thoraxjnl-2015-206938. Epub 2015 Jun 5.


Predicting Mortality in Systemic Sclerosis-Associated Interstitial Lung Disease Using Risk Prediction Models Derived From Idiopathic Pulmonary Fibrosis.

Ryerson CJ, O'Connor D, Dunne JV, Schooley F, Hague CJ, Murphy D, Leipsic J, Wilcox PG.

Chest. 2015 Nov;148(5):1268-1275. doi: 10.1378/chest.15-0003.


Absolute leukocyte telomere length in HIV-infected and uninfected individuals: evidence of accelerated cell senescence in HIV-associated chronic obstructive pulmonary disease.

Liu JC, Leung JM, Ngan DA, Nashta NF, Guillemi S, Harris M, Lima VD, Um SJ, Li Y, Tam S, Shaipanich T, Raju R, Hague C, Leipsic JA, Bourbeau J, Tan WC, Harrigan PR, Sin DD, Montaner J, Man SF.

PLoS One. 2015 Apr 17;10(4):e0124426. doi: 10.1371/journal.pone.0124426. eCollection 2015.


A case of coronary vasospasm after repeat rituximab infusion.

Ke C, Khosla A, Davis MK, Hague C, Toma M.

Case Rep Cardiol. 2015;2015:523149. doi: 10.1155/2015/523149. Epub 2015 Mar 18.


A simplified D-shaped model of the mitral annulus to facilitate CT-based sizing before transcatheter mitral valve implantation.

Blanke P, Dvir D, Cheung A, Ye J, Levine RA, Precious B, Berger A, Stub D, Hague C, Murphy D, Thompson C, Munt B, Moss R, Boone R, Wood D, Pache G, Webb J, Leipsic J.

J Cardiovasc Comput Tomogr. 2014 Nov-Dec;8(6):459-67. doi: 10.1016/j.jcct.2014.09.009. Epub 2014 Oct 7.


Qualitative and quantitative assessment of smoking-related lung disease: effect of iterative reconstruction on low-dose computed tomographic examinations.

Hague CJ, Krowchuk N, Alhassan D, Ho K, Leipsic J, Sin DD, Mayo JR, Coxson HO.

J Thorac Imaging. 2014 Nov;29(6):350-6. doi: 10.1097/RTI.0000000000000118.


Delivery of an enzyme-IGFII fusion protein to the mouse brain is therapeutic for mucopolysaccharidosis type IIIB.

Kan SH, Aoyagi-Scharber M, Le SQ, Vincelette J, Ohmi K, Bullens S, Wendt DJ, Christianson TM, Tiger PM, Brown JR, Lawrence R, Yip BK, Holtzinger J, Bagri A, Crippen-Harmon D, Vondrak KN, Chen Z, Hague CM, Woloszynek JC, Cheung DS, Webster KA, Adintori EG, Lo MJ, Wong W, Fitzpatrick PA, LeBowitz JH, Crawford BE, Bunting S, Dickson PI, Neufeld EF.

Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14870-5. doi: 10.1073/pnas.1416660111. Epub 2014 Sep 29.


Reduced iodine load with CT coronary angiography using dual-energy imaging: a prospective randomized trial compared with standard coronary CT angiography.

Raju R, Thompson AG, Lee K, Precious B, Yang TH, Berger A, Taylor C, Heilbron B, Nguyen G, Earls J, Min J, Carrascosa P, Murphy D, Hague C, Leipsic JA.

J Cardiovasc Comput Tomogr. 2014 Jul-Aug;8(4):282-8. doi: 10.1016/j.jcct.2014.06.003. Epub 2014 Jun 17.


EU alerting and reporting systems for potential chemical public health threats and hazards.

Orford R, Crabbe H, Hague C, Schaper A, Duarte-Davidson R.

Environ Int. 2014 Nov;72:15-25. doi: 10.1016/j.envint.2014.05.006. Epub 2014 Jul 12. Review.


Modulation of triglyceride and cholesterol ester synthesis impairs assembly of infectious hepatitis C virus.

Liefhebber JM, Hague CV, Zhang Q, Wakelam MJ, McLauchlan J.

J Biol Chem. 2014 Aug 1;289(31):21276-88. doi: 10.1074/jbc.M114.582999. Epub 2014 Jun 10.


Design and performance of AERHA, a high acceptance high resolution soft x-ray spectrometer.

Chiuzbăian SG, Hague CF, Avila A, Delaunay R, Jaouen N, Sacchi M, Polack F, Thomasset M, Lagarde B, Nicolaou A, Brignolo S, Baumier C, Lüning J, Mariot JM.

Rev Sci Instrum. 2014 Apr;85(4):043108. doi: 10.1063/1.4871362.


The determinants of poor respiratory health status in adults living with human immunodeficiency virus infection.

Leung JM, Liu JC, Mtambo A, Ngan D, Nashta N, Guillemi S, Harris M, Lima VD, Mattman A, Shaipanich T, Raju R, Hague C, Leipsic JA, Sin DD, Montaner JS, Man SF.

AIDS Patient Care STDS. 2014 May;28(5):240-7. doi: 10.1089/apc.2013.0373. Epub 2014 Apr 17.


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