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Is neutrophilia the key to diagnosing appendicitis in pregnancy?

Gentles JQ, Meglei G, Chen L, Hague CJ, Melck AL.

Am J Surg. 2020 Mar 26. pii: S0002-9610(20)30174-4. doi: 10.1016/j.amjsurg.2020.03.018. [Epub ahead of print]


Association of Computed Tomography Densitometry with Disease Severity, Functional Decline, and Survival in SSc-ILD.

Castillo Saldana D, Hague CJ, Murphy D, Coxson HO, Tschirren J, Peterson S, Sieren JP, Kirby M, Ryerson CJ.

Ann Am Thorac Soc. 2020 Mar 19. doi: 10.1513/AnnalsATS.201910-741OC. [Epub ahead of print]


MRI-guided pelvic lymph node biopsy via transrectal approach in prostate cancer.

Hague C, O'Connor LP, Wang AZ, Gomella PT, Yerram NK, Merino MJ, Pinto PA.

Urol Case Rep. 2020 Jan 27;30:101129. doi: 10.1016/j.eucr.2020.101129. eCollection 2020 May.


Inter-fraction robustness of intensity-modulated proton therapy in the post-operative treatment of oropharyngeal and oral cavity squamous cell carcinomas.

Hague C, Aznar M, Dong L, Fotouhi-Ghiam A, Lee LW, Li T, Lin A, Lowe M, Lukens JN, McPartlin A, O'Reilly S, Slevin N, Swisher-Mcclure S, Thomson D, Van Herk M, West C, Zou W, Teo BK.

Br J Radiol. 2020 Mar;93(1107):20190638. doi: 10.1259/bjr.20190638. Epub 2019 Dec 23.


Two indoleamines are secreted from rat pineal gland at night and act on melatonin receptors but are not night hormones.

Lee BH, Bussi IL, de la Iglesia HO, Hague C, Koh DS, Hille B.

J Pineal Res. 2020 Mar;68(2):e12622. doi: 10.1111/jpi.12622. Epub 2019 Dec 30.


Gender Disparity Among Leaders of Canadian Academic Radiology Departments.

Qamar SR, Khurshid K, Jalal S, McInnes MDF, Probyn L, Finlay K, Hague CJ, Hibbert RM, Joshi M, Rybicki FJ, Harris A, Nicolaou S, Khosa F.

AJR Am J Roentgenol. 2020 Jan;214(1):3-9. doi: 10.2214/AJR.18.20992. Epub 2019 Nov 6.


Pathologic separation of idiopathic pulmonary fibrosis from fibrotic hypersensitivity pneumonitis.

Wright JL, Churg A, Hague CJ, Wong A, Ryerson CJ.

Mod Pathol. 2020 Apr;33(4):616-625. doi: 10.1038/s41379-019-0389-3. Epub 2019 Oct 28.


Scribble co-operatively binds multiple α1D-adrenergic receptor C-terminal PDZ ligands.

Janezic EM, Harris DA, Dinh D, Lee KS, Stewart A, Hinds TR, Hsu PL, Zheng N, Hague C.

Sci Rep. 2019 Oct 1;9(1):14073. doi: 10.1038/s41598-019-50671-6.


Intracerebroventricular enzyme replacement therapy with Beta-Galactosidase reverses brain pathologies due to GM1 gangliosidosis in mice.

Chen JC, Luu AR, Wise N, Angelis R, Agrawal V, Mangini L, Vincelette J, Handyside B, Sterling HJ, Lo MJ, Wong H, Galicia N, Pacheco G, Van Vleet J, Giaramita A, Fong S, Roy SM, Hague C, Lawrence R, Bullens S, Christianson TM, d'Azzo A, Crawford BE, Bunting S, Lebowitz JH, Yogalingam G.

J Biol Chem. 2019 Sep 3. pii: jbc.RA119.009811. doi: 10.1074/jbc.RA119.009811. [Epub ahead of print]


Using Quantitative Computed Tomographic Imaging to Understand Chronic Obstructive Pulmonary Disease and Fibrotic Interstitial Lung Disease: State of the Art and Future Directions.

Castillo-Saldana D, Hague CJ, Coxson HO, Ryerson CJ.

J Thorac Imaging. 2019 Aug 7. doi: 10.1097/RTI.0000000000000440. [Epub ahead of print]


Effect of a calcium deblooming algorithm on accuracy of coronary computed tomography angiography.

Weir-McCall JR, Wang R, Halankar J, Hsieh J, Hague CJ, Rosenblatt S, Fan Z, Sellers SL, Murphy DT, Blanke P, Xu L, Leipsic JA.

J Cardiovasc Comput Tomogr. 2019 Jul 25. pii: S1934-5925(19)30063-2. doi: 10.1016/j.jcct.2019.07.007. [Epub ahead of print]


CT of Kidney Volume in Autosomal Dominant Polycystic Kidney Disease: Accuracy, Reproducibility, and Radiation Dose.

Bevilacqua MU, Hague CJ, Romann A, Sheitt H, Vasilescu DM, Yi TW, Levin A.

Radiology. 2019 Jun;291(3):660-667. doi: 10.1148/radiol.2019181830. Epub 2019 Apr 9.


Pulmonary physiology is poorly associated with radiological extent of disease in systemic sclerosis-associated interstitial lung disease.

Jhajj A, Gill HP, Hague CJ, Murphy D, Elicker B, Soon J, Sulaiman N, Castillo-Saldana D, Wilcox PG, Dunne J, Lee JS, Wolters PJ, Ley B, Jones KD, Morisset J, Ryerson CJ.

Eur Respir J. 2019 May 2;53(5). pii: 1802182. doi: 10.1183/13993003.02182-2018. Print 2019 May. No abstract available.


Current State of the Literature on Psychological and Social Sequelae of Sports-Related Concussion in School-Aged Children and Adolescents.

Wilmoth K, Tan A, Hague C, Tarkenton T, Silver CH, Didehbani N, Rossetti HC, Batjer H, Bell KR, Cullum CM.

J Exp Neurosci. 2019 Feb 20;13:1179069519830421. doi: 10.1177/1179069519830421. eCollection 2019. Review.


Phenotyping and outcomes of hospitalized COPD patients using rapid molecular diagnostics on sputum samples.

Alotaibi NM, Chen V, Hollander Z, Leipsic JA, Hague CJ, Murphy DT, DeMarco ML, FitzGerald JM, McManus BM, Ng RT, Sin DD.

Int J Chron Obstruct Pulmon Dis. 2019 Jan 23;14:311-319. doi: 10.2147/COPD.S188186. eCollection 2019.


Role of a Regional Multidisciplinary Conference in the Diagnosis of Interstitial Lung Disease.

Grewal JS, Morisset J, Fisher JH, Churg AM, Bilawich AM, Ellis J, English JC, Hague CJ, Khalil N, Leipsic J, Mayo J, Muller NL, Murphy D, Wright JL, Ryerson CJ.

Ann Am Thorac Soc. 2019 Apr;16(4):455-462. doi: 10.1513/AnnalsATS.201811-794OC.


Use of a novel atlas for muscles of mastication to reduce inter observer variability in head and neck radiotherapy contouring.

Hague C, Beasley W, Dixon L, Gaito S, Garcez K, Green A, Lee LW, Maranzano M, McPartlin A, Mistry H, Mullan D, Sykes AJ, Thomson D, Van Herk M, West CM, Slevin N.

Radiother Oncol. 2019 Jan;130:56-61. doi: 10.1016/j.radonc.2018.10.030. Epub 2018 Nov 9.


Development and Evaluation of a Competency-Based Anatomy Rotation for Diagnostic Radiology Residents During Internship Year: A Canadian Experience.

Darras KE, Spouge R, de Bruin A, Hu J, Guest W, Mar C, Hatala R, Hague C, Forster BB, Chang SD.

Can Assoc Radiol J. 2018 Nov;69(4):356-361. doi: 10.1016/j.carj.2018.07.004.


Does Systemic Sclerosis-associated Interstitial Lung Disease Burn Out? Specific Phenotypes of Disease Progression.

Guler SA, Winstone TA, Murphy D, Hague C, Soon J, Sulaiman N, Li KH, Dunne J, Wilcox PG, Ryerson CJ.

Ann Am Thorac Soc. 2018 Dec;15(12):1427-1433. doi: 10.1513/AnnalsATS.201806-362OC.


Biopsy-proven recurrent, acute, familial hypersensitivity pneumonitis: A case report and literature review.

Winstone T, Hague CJ, Churg A, Wright JL, Schellenberg R, Ryerson C.

Respir Med Case Rep. 2018 May 17;24:173-175. doi: 10.1016/j.rmcr.2018.05.007. eCollection 2018.


Oesophageal diameter is associated with severity but not progression of systemic sclerosis-associated interstitial lung disease.

Winstone TA, Hague CJ, Soon J, Sulaiman N, Murphy D, Leipsic J, Dunne JV, Wilcox PG, Ryerson CJ.

Respirology. 2018 Oct;23(10):921-926. doi: 10.1111/resp.13309. Epub 2018 Apr 11.


Prospective evaluation of relationships between radiotherapy dose to masticatory apparatus and trismus.

Hague C, Beasley W, Garcez K, Lee LW, McPartlin A, McWilliam A, Ryder D, Sykes AJ, Thomson D, van Herk M, West C, Slevin NJ.

Acta Oncol. 2018 Aug;57(8):1038-1042. doi: 10.1080/0284186X.2018.1459047. Epub 2018 Apr 9.


Patient Involvement in the Design of a Phase III Trial Comparing Intensity-modulated Proton Therapy and Intensity-modulated Radiotherapy for Oropharyngeal Cancer.

Hague C, Foran B, Hall E, Guild S, Joseph O, Moule R, Nutting C, Parsons S, Prestwich R, Slevin N, West C, Thomson D.

Clin Oncol (R Coll Radiol). 2018 May;30(5):274-276. doi: 10.1016/j.clon.2018.01.018. Epub 2018 Feb 17. No abstract available.


Phenotyping COPD exacerbations using imaging and blood-based biomarkers.

Alotaibi NM, Chen V, Hollander Z, Hague CJ, Murphy DT, Leipsic JA, DeMarco ML, FitzGerald JM, McManus BM, Ng RT, Sin DD.

Int J Chron Obstruct Pulmon Dis. 2018 Jan 8;13:217-229. doi: 10.2147/COPD.S152484. eCollection 2018.


Dual energy computed tomography should be a first line preoperative localization imaging test for primary hyperparathyroidism patients.

Hiebert J, Hague C, Hou S, Wiseman SM.

Am J Surg. 2018 May;215(5):788-792. doi: 10.1016/j.amjsurg.2017.11.048. Epub 2018 Jan 5.


Coronary lumen volume to myocardial mass ratio in primary microvascular angina.

Grover R, Leipsic JA, Mooney J, Kueh SH, Ohana M, Nørgaard BL, Eftekhari A, Bax JJ, Murphy DT, Hague CJ, Seidman MA, Blanke P, Sedlak T, Sellers SL.

J Cardiovasc Comput Tomogr. 2017 Nov;11(6):423-428. doi: 10.1016/j.jcct.2017.09.015. Epub 2017 Sep 22.


Fractional flow reserve derived from coronary computed tomography angiography reclassification rate using value distal to lesion compared to lowest value.

Kueh SH, Mooney J, Ohana M, Kim U, Blanke P, Grover R, Sellers S, Ellis J, Murphy D, Hague C, Bax JJ, Nørgaard BL, Rabbat M, Leipsic JA.

J Cardiovasc Comput Tomogr. 2017 Nov;11(6):462-467. doi: 10.1016/j.jcct.2017.09.009. Epub 2017 Sep 21.


Total Airway Count on Computed Tomography and the Risk of Chronic Obstructive Pulmonary Disease Progression. Findings from a Population-based Study.

Kirby M, Tanabe N, Tan WC, Zhou G, Obeidat M, Hague CJ, Leipsic J, Bourbeau J, Sin DD, Hogg JC, Coxson HO; CanCOLD Collaborative Research Group; Canadian Respiratory Research Network; CanCOLD Collaborative Research Group, the Canadian Respiratory Research Network.

Am J Respir Crit Care Med. 2018 Jan 1;197(1):56-65. doi: 10.1164/rccm.201704-0692OC.


A Novel Method of Estimating Small Airway Disease Using Inspiratory-to-Expiratory Computed Tomography.

Kirby M, Yin Y, Tschirren J, Tan WC, Leipsic J, Hague CJ, Bourbeau J, Sin DD, Hogg JC, Coxson HO; CanCOLD Collaborative Research Group and the Canadian Respiratory Research Network.

Respiration. 2017;94(4):336-345. doi: 10.1159/000478865. Epub 2017 Aug 23.


Utility of Magnetic Resonance Imaging for the Diagnosis of Appendicitis During Pregnancy: A Canadian Experience.

Burns M, Hague CJ, Vos P, Tiwari P, Wiseman SM.

Can Assoc Radiol J. 2017 Nov;68(4):392-400. doi: 10.1016/j.carj.2017.02.004. Epub 2017 Jul 18.


Neuropsychological outcomes of pediatric demyelinating diseases: a review.

Tan A, Hague C, Greenberg BM, Harder L.

Child Neuropsychol. 2018 Jul;24(5):575-597. doi: 10.1080/09297049.2017.1339785. Epub 2017 Jun 21. Review.


Cough is less common and less severe in systemic sclerosis-associated interstitial lung disease compared to other fibrotic interstitial lung diseases.

Cheng JZ, Wilcox PG, Glaspole I, Corte TJ, Murphy D, Hague CJ, Ryerson CJ.

Respirology. 2017 Nov;22(8):1592-1597. doi: 10.1111/resp.13084. Epub 2017 May 23.


Evaluation of endorectal ultrasound (ERUS) and MRI for prediction of circumferential resection margin (CRM) for rectal cancer.

Tsai C, Hague C, Xiong W, Raval M, Karimuddin A, Brown C, Phang PT.

Am J Surg. 2017 May;213(5):936-942. doi: 10.1016/j.amjsurg.2017.03.029. Epub 2017 Mar 27.


C-reactive protein and N-terminal prohormone brain natriuretic peptide as biomarkers in acute exacerbations of COPD leading to hospitalizations.

Chen YR, Chen V, Hollander Z, Leipsic JA, Hague CJ, DeMarco ML, FitzGerald JM, McManus BM, Ng RT, Sin DD.

PLoS One. 2017 Mar 22;12(3):e0174063. doi: 10.1371/journal.pone.0174063. eCollection 2017.


Testicular Vasculitis: A Sonographic and Pathologic Diagnosis.

Dixit A, Hague C, Bicknell S.

Case Rep Radiol. 2017;2017:8923621. doi: 10.1155/2017/8923621. Epub 2017 Jan 26.


Label-Free Dynamic Mass Redistribution Reveals Low-Density, Prosurvival α1B-Adrenergic Receptors in Human SW480 Colon Carcinoma Cells.

Harris DA, Park JM, Lee KS, Xu C, Stella N, Hague C.

J Pharmacol Exp Ther. 2017 May;361(2):219-228. doi: 10.1124/jpet.116.237255. Epub 2017 Feb 14.


Comparison of low-dose coronary artery calcium scoring using low tube current technique and hybrid iterative reconstruction vs. filtered back projection.

Sulaiman N, Soon J, Park JK, Naoum C, Kueh SH, Blanke P, Murphy D, Ellis J, Hague CJ, Leipsic J.

Clin Imaging. 2017 May - Jun;43:19-23. doi: 10.1016/j.clinimag.2017.01.017. Epub 2017 Feb 2.


Cellular Uptake and Delivery of Myeloperoxidase to Lysosomes Promote Lipofuscin Degradation and Lysosomal Stress in Retinal Cells.

Yogalingam G, Lee AR, Mackenzie DS, Maures TJ, Rafalko A, Prill H, Berguig GY, Hague C, Christianson T, Bell SM, LeBowitz JH.

J Biol Chem. 2017 Mar 10;292(10):4255-4265. doi: 10.1074/jbc.M116.739441. Epub 2017 Jan 23.


Emphysema Distribution and Diffusion Capacity Predict Emphysema Progression in Human Immunodeficiency Virus Infection.

Leung JM, Malagoli A, Santoro A, Besutti G, Ligabue G, Scaglioni R, Dai D, Hague C, Leipsic J, Sin DD, Man SP, Guaraldi G.

PLoS One. 2016 Nov 30;11(11):e0167247. doi: 10.1371/journal.pone.0167247. eCollection 2016.


Findings on Thoracic Computed Tomography Scans and Respiratory Outcomes in Persons with and without Chronic Obstructive Pulmonary Disease: A Population-Based Cohort Study.

Tan WC, Hague CJ, Leipsic J, Bourbeau J, Zheng L, Li PZ, Sin DD, Coxson HO, Kirby M, Hogg JC, Raju R, Road J, O'Donnell DE, Maltais F, Hernandez P, Cowie R, Chapman KR, Marciniuk DD, FitzGerald JM, Aaron SD; Canadian Respiratory Research Network and the CanCOLD Collaborative Research group.

PLoS One. 2016 Nov 18;11(11):e0166745. doi: 10.1371/journal.pone.0166745. eCollection 2016.


The bronchial epithelial cell bacterial microbiome and host response in patients infected with human immunodeficiency virus.

Sze MA, Xu S, Leung JM, Vucic EA, Shaipanich T, Moghadam A, Harris M, Guillemi S, Sinha S, Nislow C, Murphy D, Hague C, Leipsic J, Lam S, Lam W, Montaner JS, Sin DD, Man SF.

BMC Pulm Med. 2016 Nov 9;16(1):142.


The effect of a whole heart motion-correction algorithm on CT image quality and measurement reproducibility in Pre-TAVR aortic annulus evaluation.

Soon J, Sulaiman N, Park JK, Kueh SH, Naoum C, Murphy D, Ellis J, Hague CJ, Blanke P, Leipsic J.

J Cardiovasc Comput Tomogr. 2016 Sep-Oct;10(5):386-90. doi: 10.1016/j.jcct.2016.08.001. Epub 2016 Aug 21.


Aggressive angiomyxoma presenting as massive irreducible vaginal prolapse.

Larouche M, Hague CJ, Masoudi H, Geoffrion R.

Int Urogynecol J. 2016 Dec;27(12):1933-1934. Epub 2016 Aug 10. No abstract available.


Endogenous N-terminal Domain Cleavage Modulates α1D-Adrenergic Receptor Pharmacodynamics.

Kountz TS, Lee KS, Aggarwal-Howarth S, Curran E, Park JM, Harris DA, Stewart A, Hendrickson J, Camp ND, Wolf-Yadlin A, Wang EH, Scott JD, Hague C.

J Biol Chem. 2016 Aug 26;291(35):18210-21. doi: 10.1074/jbc.M116.729517. Epub 2016 Jul 5.


Clinical experience with radium-223 in the treatment of patients with advanced castrate-resistant prostate cancer and symptomatic bone metastases.

Hague C, Logue JP.

Ther Adv Urol. 2016 Jun;8(3):175-80. doi: 10.1177/1756287216629870. Epub 2016 Feb 25. Review.


The current utility of ultrasound in the diagnosis of acute appendicitis.

Lourenco P, Brown J, Leipsic J, Hague C.

Clin Imaging. 2016 Sep-Oct;40(5):944-8. doi: 10.1016/j.clinimag.2016.03.012. Epub 2016 Apr 2.


Current Views on Clinical Oncology Training from the 2015 Oncology Registrars' Forum Survey.

Kosmin M, Brown S, Hague C, Said J, Wells L, Wilson C.

Clin Oncol (R Coll Radiol). 2016 Sep;28(9):e121-5. doi: 10.1016/j.clon.2016.04.043. Epub 2016 May 12.


Implementation of a Longitudinal Introduction to Radiology Course During Internship Year Improves Diagnostic Radiology Residents' Academic and Clinical Skills: A Canadian Experience.

Darras KE, Worthington A, Russell D, Hou DJ, Forster BB, Hague CJ, Mar C, Chang SD.

Acad Radiol. 2016 Jul;23(7):848-60. doi: 10.1016/j.acra.2016.03.007. Epub 2016 May 10.


Rapid automatized naming (RAN) in children with ADHD: An ex-Gaussian analysis.

Ryan M, Jacobson LA, Hague C, Bellows A, Denckla MB, Mahone EM.

Child Neuropsychol. 2017 Jul;23(5):571-587. doi: 10.1080/09297049.2016.1172560. Epub 2016 Apr 24.


Development of a new categorization system for pesticides exposure to support harmonized reporting between EU Member States.

Settimi L, Orford R, Davanzo F, Hague C, Desel H, Pelclova D, Dragelyte G, Mathieu-Nolf M, Adams R, Duarte-Davidson R.

Environ Int. 2016 May;91:332-40. doi: 10.1016/j.envint.2016.02.034. Epub 2016 Mar 24.


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