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Items: 1 to 50 of 74

1.

Thy-1 as an Integrator of Diverse Extracellular Signals.

Hagood JS.

Front Cell Dev Biol. 2019 Feb 25;7:26. doi: 10.3389/fcell.2019.00026. eCollection 2019. Review.

2.

Outsourcing Invasion, a Novel Function for Extracellular Vesicles in the Lung.

Shentu TP, Hagood JS.

Am J Respir Cell Mol Biol. 2019 Mar;60(3):251-252. doi: 10.1165/rcmb.2018-0345ED. No abstract available.

PMID:
30372117
3.

αvβ3 Integrin drives fibroblast contraction and strain stiffening of soft provisional matrix during progressive fibrosis.

Fiore VF, Wong SS, Tran C, Tan C, Xu W, Sulchek T, White ES, Hagood JS, Barker TH.

JCI Insight. 2018 Oct 18;3(20). pii: 97597. doi: 10.1172/jci.insight.97597.

4.

Epigenetic Regulation of Myofibroblast Phenotypes in Fibrosis.

Duong TE, Hagood JS.

Curr Pathobiol Rep. 2018 Mar;6(1):79-96. doi: 10.1007/s40139-018-0155-0. Epub 2018 Mar 16.

5.

iDREM: Interactive visualization of dynamic regulatory networks.

Ding J, Hagood JS, Ambalavanan N, Kaminski N, Bar-Joseph Z.

PLoS Comput Biol. 2018 Mar 14;14(3):e1006019. doi: 10.1371/journal.pcbi.1006019. eCollection 2018 Mar.

6.

Extracellular matrix in lung development, homeostasis and disease.

Zhou Y, Horowitz JC, Naba A, Ambalavanan N, Atabai K, Balestrini J, Bitterman PB, Corley RA, Ding BS, Engler AJ, Hansen KC, Hagood JS, Kheradmand F, Lin QS, Neptune E, Niklason L, Ortiz LA, Parks WC, Tschumperlin DJ, White ES, Chapman HA, Thannickal VJ.

Matrix Biol. 2018 Nov;73:77-104. doi: 10.1016/j.matbio.2018.03.005. Epub 2018 Mar 8. Review.

PMID:
29524630
7.

Thy-1 dependent uptake of mesenchymal stem cell-derived extracellular vesicles blocks myofibroblastic differentiation.

Shentu TP, Huang TS, Cernelc-Kohan M, Chan J, Wong SS, Espinoza CR, Tan C, Gramaglia I, van der Heyde H, Chien S, Hagood JS.

Sci Rep. 2017 Dec 22;7(1):18052. doi: 10.1038/s41598-017-18288-9.

8.

Rac2 is required for alternative macrophage activation and bleomycin induced pulmonary fibrosis; a macrophage autonomous phenotype.

Joshi S, Singh AR, Wong SS, Zulcic M, Jiang M, Pardo A, Selman M, Hagood JS, Durden DL.

PLoS One. 2017 Aug 17;12(8):e0182851. doi: 10.1371/journal.pone.0182851. eCollection 2017.

9.

LungMAP: The Molecular Atlas of Lung Development Program.

Ardini-Poleske ME, Clark RF, Ansong C, Carson JP, Corley RA, Deutsch GH, Hagood JS, Kaminski N, Mariani TJ, Potter SS, Pryhuber GS, Warburton D, Whitsett JA, Palmer SM, Ambalavanan N; LungMAP Consortium.

Am J Physiol Lung Cell Mol Physiol. 2017 Nov 1;313(5):L733-L740. doi: 10.1152/ajplung.00139.2017. Epub 2017 Aug 10. Review.

10.

Thy-1 interaction with Fas in lipid rafts regulates fibroblast apoptosis and lung injury resolution.

Liu X, Wong SS, Taype CA, Kim J, Shentu TP, Espinoza CR, Finley JC, Bradley JE, Head BP, Patel HH, Mah EJ, Hagood JS.

Lab Invest. 2017 Mar;97(3):256-267. doi: 10.1038/labinvest.2016.145. Epub 2017 Feb 6.

11.

Selecting the most appropriate time points to profile in high-throughput studies.

Kleyman M, Sefer E, Nicola T, Espinoza C, Chhabra D, Hagood JS, Kaminski N, Ambalavanan N, Bar-Joseph Z.

Elife. 2017 Jan 26;6. pii: e18541. doi: 10.7554/eLife.18541.

12.

Risk and impact of pulmonary complications in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study.

Dietz AC, Chen Y, Yasui Y, Ness KK, Hagood JS, Chow EJ, Stovall M, Neglia JP, Oeffinger KC, Mertens AC, Robison LL, Armstrong GT, Mulrooney DA.

Cancer. 2016 Dec 1;122(23):3687-3696. doi: 10.1002/cncr.30200. Epub 2016 Aug 9.

13.

Mechanisms of Lung Fibrosis Resolution.

Glasser SW, Hagood JS, Wong S, Taype CA, Madala SK, Hardie WD.

Am J Pathol. 2016 May;186(5):1066-77. doi: 10.1016/j.ajpath.2016.01.018. Epub 2016 Mar 25. Review.

14.

Cigarette Smoke Enhances the Expression of Profibrotic Molecules in Alveolar Epithelial Cells.

Checa M, Hagood JS, Velazquez-Cruz R, Ruiz V, García-De-Alba C, Rangel-Escareño C, Urrea F, Becerril C, Montaño M, García-Trejo S, Cisneros Lira J, Aquino-Gálvez A, Pardo A, Selman M.

PLoS One. 2016 Mar 2;11(3):e0150383. doi: 10.1371/journal.pone.0150383. eCollection 2016.

15.

Conformational coupling of integrin and Thy-1 regulates Fyn priming and fibroblast mechanotransduction.

Fiore VF, Strane PW, Bryksin AV, White ES, Hagood JS, Barker TH.

J Cell Biol. 2015 Oct 12;211(1):173-90. doi: 10.1083/jcb.201505007.

16.

Matrix metalloproteinases as therapeutic targets for idiopathic pulmonary fibrosis.

Craig VJ, Zhang L, Hagood JS, Owen CA.

Am J Respir Cell Mol Biol. 2015 Nov;53(5):585-600. doi: 10.1165/rcmb.2015-0020TR. Review.

17.
18.

Beyond the genome: epigenetic mechanisms in lung remodeling.

Hagood JS.

Physiology (Bethesda). 2014 May;29(3):177-85. doi: 10.1152/physiol.00048.2013. Review.

19.

Histone deacetylase inhibition promotes fibroblast apoptosis and ameliorates pulmonary fibrosis in mice.

Sanders YY, Hagood JS, Liu H, Zhang W, Ambalavanan N, Thannickal VJ.

Eur Respir J. 2014 May;43(5):1448-58. doi: 10.1183/09031936.00095113. Epub 2014 Mar 6.

20.

Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report.

Blackwell TS, Tager AM, Borok Z, Moore BB, Schwartz DA, Anstrom KJ, Bar-Joseph Z, Bitterman P, Blackburn MR, Bradford W, Brown KK, Chapman HA, Collard HR, Cosgrove GP, Deterding R, Doyle R, Flaherty KR, Garcia CK, Hagood JS, Henke CA, Herzog E, Hogaboam CM, Horowitz JC, King TE Jr, Loyd JE, Lawson WE, Marsh CB, Noble PW, Noth I, Sheppard D, Olsson J, Ortiz LA, O'Riordan TG, Oury TD, Raghu G, Roman J, Sime PJ, Sisson TH, Tschumperlin D, Violette SM, Weaver TE, Wells RG, White ES, Kaminski N, Martinez FJ, Wynn TA, Thannickal VJ, Eu JP.

Am J Respir Crit Care Med. 2014 Jan 15;189(2):214-22. doi: 10.1164/rccm.201306-1141WS.

21.

Pulmonary interstitial glycogenosis in a patient ultimately diagnosed with Noonan syndrome.

Ross MK, Ellis LS, Bird LM, Hagood JS.

Pediatr Pulmonol. 2014 May;49(5):508-11. doi: 10.1002/ppul.22871. Epub 2013 Sep 3.

PMID:
24039098
22.

Myofibroblast differentiation and enhanced TGF-B signaling in cystic fibrosis lung disease.

Harris WT, Kelly DR, Zhou Y, Wang D, MacEwen M, Hagood JS, Clancy JP, Ambalavanan N, Sorscher EJ.

PLoS One. 2013 Aug 12;8(8):e70196. doi: 10.1371/journal.pone.0070196. eCollection 2013. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/d0132de3-56ca-4258-9119-bdab0ceb2cff. Macewen, Mark [corrected to MacEwen, Mark].

23.

An official American Thoracic Society clinical practice guideline: classification, evaluation, and management of childhood interstitial lung disease in infancy.

Kurland G, Deterding RR, Hagood JS, Young LR, Brody AS, Castile RG, Dell S, Fan LL, Hamvas A, Hilman BC, Langston C, Nogee LM, Redding GJ; American Thoracic Society Committee on Childhood Interstitial Lung Disease (chILD) and the chILD Research Network.

Am J Respir Crit Care Med. 2013 Aug 1;188(3):376-94. doi: 10.1164/rccm.201305-0923ST. Review.

24.

The (pediatric pulmonary) world is flat. The spread of Internet-based pediatric pulmonary case conferences.

Stokes DC, McBride JT, Hagood JS, Lesser DJ, Taylor JB.

Ann Am Thorac Soc. 2013 Jun;10(3):274-5. doi: 10.1513/AnnalsATS.201301-005LE. Review. No abstract available.

PMID:
23802832
25.

Diffuse lung disease in children: summary of a scientific conference.

Hamvas A, Deterding R, Balch WE, Schwartz DA, Albertine KH, Whitsett JA, Cardoso WV, Kotton DN, Kourembanas S, Hagood JS.

Pediatr Pulmonol. 2014 Apr;49(4):400-9. doi: 10.1002/ppul.22805. Epub 2013 Jun 24.

26.

Effect of the GPI anchor of human Thy-1 on antibody recognition and function.

Bradley JE, Chan JM, Hagood JS.

Lab Invest. 2013 Mar;93(3):365-74. doi: 10.1038/labinvest.2012.178. Epub 2013 Jan 28.

27.

Systems biology of lung development and regeneration: current knowledge and recommendations for future research.

Hagood JS, Ambalavanan N.

Wiley Interdiscip Rev Syst Biol Med. 2013 Mar-Apr;5(2):125-33. doi: 10.1002/wsbm.1205. Epub 2013 Jan 4. Review.

PMID:
23293056
28.

Diffuse and interstitial lung disease and childhood rheumatologic disorders.

Dell S, Cernelc-Kohan M, Hagood JS.

Curr Opin Rheumatol. 2012 Sep;24(5):530-40. doi: 10.1097/BOR.0b013e328356813e. Review.

PMID:
22820514
29.

Altered DNA methylation profile in idiopathic pulmonary fibrosis.

Sanders YY, Ambalavanan N, Halloran B, Zhang X, Liu H, Crossman DK, Bray M, Zhang K, Thannickal VJ, Hagood JS.

Am J Respir Crit Care Med. 2012 Sep 15;186(6):525-35. doi: 10.1164/rccm.201201-0077OC. Epub 2012 Jun 14.

30.

Biological insights from clinical trials and networks.

Thannickal VJ, Hagood JS.

Am J Respir Crit Care Med. 2012 Mar 1;185(5):475-6. doi: 10.1164/rccm.201201-0047ED. No abstract available.

31.

Thy-1 signals through PPARγ to promote lipofibroblast differentiation in the developing lung.

Varisco BM, Ambalavanan N, Whitsett JA, Hagood JS.

Am J Respir Cell Mol Biol. 2012 Jun;46(6):765-72. doi: 10.1165/rcmb.2011-0316OC. Epub 2012 Jan 20.

32.

The distribution of immunomodulatory cells in the lungs of patients with idiopathic pulmonary fibrosis.

Nuovo GJ, Hagood JS, Magro CM, Chin N, Kapil R, Davis L, Marsh CB, Folcik VA.

Mod Pathol. 2012 Mar;25(3):416-33. doi: 10.1038/modpathol.2011.166. Epub 2011 Oct 28.

33.

Myofibroblast differentiation and survival in fibrotic disease.

Kis K, Liu X, Hagood JS.

Expert Rev Mol Med. 2011 Aug 23;13:e27. doi: 10.1017/S1462399411001967. Review.

34.

Absence of Thy-1 results in TGF-β induced MMP-9 expression and confers a profibrotic phenotype to human lung fibroblasts.

Ramírez G, Hagood JS, Sanders Y, Ramírez R, Becerril C, Segura L, Barrera L, Selman M, Pardo A.

Lab Invest. 2011 Aug;91(8):1206-18. doi: 10.1038/labinvest.2011.80. Epub 2011 May 16.

35.

Epigenetic regulation of thy-1 by histone deacetylase inhibitor in rat lung fibroblasts.

Sanders YY, Tollefsbol TO, Varisco BM, Hagood JS.

Am J Respir Cell Mol Biol. 2011 Jul;45(1):16-23. doi: 10.1165/rcmb.2010-0154OC. Epub 2010 Aug 19.

36.

Signaling pathways in the epithelial origins of pulmonary fibrosis.

Hardie WD, Hagood JS, Dave V, Perl AK, Whitsett JA, Korfhagen TR, Glasser S.

Cell Cycle. 2010 Jul 15;9(14):2769-76. Epub 2010 Jul 3. Review.

37.

Thy-1 attenuates TNF-alpha-activated gene expression in mouse embryonic fibroblasts via Src family kinase.

Shan B, Hagood JS, Zhuo Y, Nguyen HT, MacEwen M, Morris GF, Lasky JA.

PLoS One. 2010 Jul 19;5(7):e11662. doi: 10.1371/journal.pone.0011662.

38.

Thy-1-integrin alphav beta5 interactions inhibit lung fibroblast contraction-induced latent transforming growth factor-beta1 activation and myofibroblast differentiation.

Zhou Y, Hagood JS, Lu B, Merryman WD, Murphy-Ullrich JE.

J Biol Chem. 2010 Jul 16;285(29):22382-93. doi: 10.1074/jbc.M110.126227. Epub 2010 May 12.

39.

Oxidative modification of nuclear mitogen-activated protein kinase phosphatase 1 is involved in transforming growth factor beta1-induced expression of plasminogen activator inhibitor 1 in fibroblasts.

Liu RM, Choi J, Wu JH, Gaston Pravia KA, Lewis KM, Brand JD, Mochel NS, Krzywanski DM, Lambeth JD, Hagood JS, Forman HJ, Thannickal VJ, Postlethwait EM.

J Biol Chem. 2010 May 21;285(21):16239-47. doi: 10.1074/jbc.M110.111732. Epub 2010 Mar 12.

40.

Round Table Discussion: Children's Interstitial Lung Disease.

Deterding RR, Brody AS, Hagood JS, Young LR.

Pediatr Allergy Immunol Pulmonol. 2010 Mar;23(1):91-96. No abstract available.

41.

ChILD Family Education.

McDougal J, Gettys A, Hagood JS.

Pediatr Allergy Immunol Pulmonol. 2010 Mar;23(1):87-90.

42.

Pathogenesis of Interstitial Lung Disease in Children and Adults.

Glasser SW, Hardie WD, Hagood JS.

Pediatr Allergy Immunol Pulmonol. 2010 Mar;23(1):9-14.

43.

Emerging concepts in the pathogenesis of lung fibrosis.

Hardie WD, Glasser SW, Hagood JS.

Am J Pathol. 2009 Jul;175(1):3-16. doi: 10.2353/ajpath.2009.081170. Epub 2009 Jun 4. Review.

44.

Roles and regulation of Thy-1, a context-dependent modulator of cell phenotype.

Bradley JE, Ramirez G, Hagood JS.

Biofactors. 2009 May-Jun;35(3):258-65. doi: 10.1002/biof.41. Review.

45.

Loss of Thy-1 inhibits alveolar development in the newborn mouse lung.

Nicola T, Hagood JS, James ML, Macewen MW, Williams TA, Hewitt MM, Schwiebert L, Bulger A, Oparil S, Chen YF, Ambalavanan N.

Am J Physiol Lung Cell Mol Physiol. 2009 May;296(5):L738-50. doi: 10.1152/ajplung.90603.2008. Epub 2009 Mar 6.

46.

Strategic plan for pediatric respiratory diseases research: an NHLBI working group report.

Castro M, Ramirez MI, Gern JE, Cutting G, Redding G, Hagood JS, Whitsett J, Abman S, Raj JU, Barst R, Kato GJ, Gozal D, Haddad GG, Prabhakar NR, Gauda E, Martinez FD, Tepper R, Wood RE, Accurso F, Teague WG, Venegas J, Cole FS, Wright RJ.

Proc Am Thorac Soc. 2009 Jan 15;6(1):1-10. doi: 10.1513/pats.200810-116CB.

47.

Low intensity shear stress increases endothelial ELR+ CXC chemokine production via a focal adhesion kinase-p38{beta} MAPK-NF-{kappa}B pathway.

Shaik SS, Soltau TD, Chaturvedi G, Totapally B, Hagood JS, Andrews WW, Athar M, Voitenok NN, Killingsworth CR, Patel RP, Fallon MB, Maheshwari A.

J Biol Chem. 2009 Feb 27;284(9):5945-55. doi: 10.1074/jbc.M807205200. Epub 2008 Dec 31.

48.

Strategic plan for pediatric respiratory diseases research: an NHLBI working group report.

Abman S, Jobe A, Chernick V, Blaisdell C, Castro M, Ramirez MI, Gern JE, Cutting G, Redding G, Hagood JS, Whitsett J, Abman S, Raj JU, Barst R, Kato GJ, Gozal D, Haddad GG, Prabhakar NR, Gauda E, Martinez FD, Tepper R, Wood RE, Accurso F, Teague WG, Venegas J, Cole FS, Wright RJ, Gail D, Hamvas A, Kercsmar C, Kiley J, Weinmann G; NHLBI working group report.

Pediatr Pulmonol. 2009 Jan;44(1):2-13. doi: 10.1002/ppul.20973.

49.

Latent transforming growth factor-beta-binding protein-4 regulates transforming growth factor-beta1 bioavailability for activation by fibrogenic lung fibroblasts in response to bleomycin.

Zhou Y, Koli K, Hagood JS, Miao M, Mavalli M, Rifkin DB, Murphy-Ullrich JE.

Am J Pathol. 2009 Jan;174(1):21-33. doi: 10.2353/ajpath.2009.080620. Epub 2008 Dec 4.

50.

Getting a grip on Thy-1 signaling.

Barker TH, Hagood JS.

Biochim Biophys Acta. 2009 May;1793(5):921-3. doi: 10.1016/j.bbamcr.2008.10.004. Epub 2008 Oct 25. Review.

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