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Items: 15

1.

Potent LpxC Inhibitors with In Vitro Activity Against Multi-Drug Resistant Pseudomonas aeruginosa.

Krause KM, Haglund CM, Hebner C, Serio AW, Lee G, Nieto V, Cohen F, Kane TR, Machajewski TD, Hildebrandt D, Pillar C, Thwaites M, Hall D, Miesel L, Hackel M, Burek A, Andrews LD, Armstrong E, Swem L, Jubb A, Cirz RT.

Antimicrob Agents Chemother. 2019 Aug 26. pii: AAC.00977-19. doi: 10.1128/AAC.00977-19. [Epub ahead of print]

PMID:
31451507
2.

Optimization and Mechanistic Characterization of Pyridopyrimidine Inhibitors of Bacterial Biotin Carboxylase.

Andrews LD, Kane TR, Dozzo P, Haglund CM, Hilderbrandt DJ, Linsell MS, Machajewski T, McEnroe G, Serio AW, Wlasichuk KB, Neau DB, Pakhomova S, Waldrop GL, Sharp M, Pogliano J, Cirz RT, Cohen F.

J Med Chem. 2019 Aug 22;62(16):7489-7505. doi: 10.1021/acs.jmedchem.9b00625. Epub 2019 Aug 9.

PMID:
31306011
3.

Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety.

Cohen F, Aggen JB, Andrews LD, Assar Z, Boggs J, Choi T, Dozzo P, Easterday AN, Haglund CM, Hildebrandt DJ, Holt MC, Joly K, Jubb A, Kamal Z, Kane TR, Konradi AW, Krause KM, Linsell MS, Machajewski TD, Miroshnikova O, Moser HE, Nieto V, Phan T, Plato C, Serio AW, Seroogy J, Shakhmin A, Stein AJ, Sun AD, Sviridov S, Wang Z, Wlasichuk K, Yang W, Zhou X, Zhu H, Cirz RT.

ChemMedChem. 2019 Aug 20;14(16):1560-1572. doi: 10.1002/cmdc.201900287. Epub 2019 Aug 5.

PMID:
31283109
4.

Cardiac channel molecular autopsy: insights from 173 consecutive cases of autopsy-negative sudden unexplained death referred for postmortem genetic testing.

Tester DJ, Medeiros-Domingo A, Will ML, Haglund CM, Ackerman MJ.

Mayo Clin Proc. 2012 Jun;87(6):524-39. doi: 10.1016/j.mayocp.2012.02.017.

5.

Pathogens and polymers: microbe-host interactions illuminate the cytoskeleton.

Haglund CM, Welch MD.

J Cell Biol. 2011 Oct 3;195(1):7-17. doi: 10.1083/jcb.201103148. Review.

6.

Rickettsia Sca2 is a bacterial formin-like mediator of actin-based motility.

Haglund CM, Choe JE, Skau CT, Kovar DR, Welch MD.

Nat Cell Biol. 2010 Nov;12(11):1057-63. doi: 10.1038/ncb2109. Epub 2010 Oct 24.

7.

Implantable cardioverter defibrillator therapy for congenital long QT syndrome: a single-center experience.

Horner JM, Kinoshita M, Webster TL, Haglund CM, Friedman PA, Ackerman MJ.

Heart Rhythm. 2010 Nov;7(11):1616-22. doi: 10.1016/j.hrthm.2010.08.023. Epub 2010 Sep 17.

PMID:
20816872
8.

Defining a core set of actin cytoskeletal proteins critical for actin-based motility of Rickettsia.

Serio AW, Jeng RL, Haglund CM, Reed SC, Welch MD.

Cell Host Microbe. 2010 May 20;7(5):388-98. doi: 10.1016/j.chom.2010.04.008.

9.

Identification of a possible pathogenic link between congenital long QT syndrome and epilepsy.

Johnson JN, Hofman N, Haglund CM, Cascino GD, Wilde AA, Ackerman MJ.

Neurology. 2009 Jan 20;72(3):224-31. doi: 10.1212/01.wnl.0000335760.02995.ca. Epub 2008 Nov 26.

10.

Diagnostic miscues in congenital long-QT syndrome.

Taggart NW, Haglund CM, Tester DJ, Ackerman MJ.

Circulation. 2007 May 22;115(20):2613-20. Epub 2007 May 14.

PMID:
17502575
11.

Genotypic heterogeneity and phenotypic mimicry among unrelated patients referred for catecholaminergic polymorphic ventricular tachycardia genetic testing.

Tester DJ, Arya P, Will M, Haglund CM, Farley AL, Makielski JC, Ackerman MJ.

Heart Rhythm. 2006 Jul;3(7):800-5. Epub 2006 Mar 28.

PMID:
16818210
12.

Effect of clinical phenotype on yield of long QT syndrome genetic testing.

Tester DJ, Will ML, Haglund CM, Ackerman MJ.

J Am Coll Cardiol. 2006 Feb 21;47(4):764-8. Epub 2006 Jan 26.

13.

Compendium of cardiac channel mutations in 541 consecutive unrelated patients referred for long QT syndrome genetic testing.

Tester DJ, Will ML, Haglund CM, Ackerman MJ.

Heart Rhythm. 2005 May;2(5):507-17.

PMID:
15840476
14.

Functional genomics of eukaryotic photosynthesis using insertional mutagenesis of Chlamydomonas reinhardtii.

Dent RM, Haglund CM, Chin BL, Kobayashi MC, Niyogi KK.

Plant Physiol. 2005 Feb;137(2):545-56. Epub 2005 Jan 14.

15.

Spectrum and frequency of cardiac channel defects in swimming-triggered arrhythmia syndromes.

Choi G, Kopplin LJ, Tester DJ, Will ML, Haglund CM, Ackerman MJ.

Circulation. 2004 Oct 12;110(15):2119-24. Epub 2004 Oct 4.

PMID:
15466642

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