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Items: 1 to 50 of 372

1.

Evaluation of toll-like receptors as prognostic biomarkers in gastric cancer: high tissue TLR5 predicts a better outcome.

Kasurinen A, Hagström J, Laitinen A, Kokkola A, Böckelman C, Haglund C.

Sci Rep. 2019 Aug 29;9(1):12553. doi: 10.1038/s41598-019-49111-2.

2.

Potent LpxC Inhibitors with In Vitro Activity Against Multi-Drug Resistant Pseudomonas aeruginosa.

Krause KM, Haglund CM, Hebner C, Serio AW, Lee G, Nieto V, Cohen F, Kane TR, Machajewski TD, Hildebrandt D, Pillar C, Thwaites M, Hall D, Miesel L, Hackel M, Burek A, Andrews LD, Armstrong E, Swem L, Jubb A, Cirz RT.

Antimicrob Agents Chemother. 2019 Aug 26. pii: AAC.00977-19. doi: 10.1128/AAC.00977-19. [Epub ahead of print]

PMID:
31451507
3.

Machine learning application for prediction of locoregional recurrences in early oral tongue cancer: a Web-based prognostic tool.

Alabi RO, Elmusrati M, Sawazaki-Calone I, Kowalski LP, Haglund C, Coletta RD, Mäkitie AA, Salo T, Leivo I, Almangush A.

Virchows Arch. 2019 Aug 17. doi: 10.1007/s00428-019-02642-5. [Epub ahead of print]

PMID:
31422502
4.

Performance of Finnish biobanks in nationwide pulmonary carcinoid tumour research.

Vesterinen T, Salmenkivi K, Mustonen H, Kuopio T, Lappi-Blanco E, Paavonen T, Vainio P, Knuuttila A, Carpén O, Haglund C, Arola J.

Virchows Arch. 2019 Aug 5. doi: 10.1007/s00428-019-02625-6. [Epub ahead of print]

PMID:
31385069
5.

Immunohistochemical Expression of Somatostatin Receptor Subtypes in a Panel of Neuroendocrine Neoplasias.

Remes SM, Leijon HL, Vesterinen TJ, Arola JT, Haglund CH.

J Histochem Cytochem. 2019 Jun 10:22155419856900. doi: 10.1369/0022155419856900. [Epub ahead of print]

PMID:
31381461
6.

L1TD1 - a prognostic marker for colon cancer.

Chakroborty D, Emani MR, Klén R, Böckelman C, Hagström J, Haglund C, Ristimäki A, Lahesmaa R, Elo LL.

BMC Cancer. 2019 Jul 23;19(1):727. doi: 10.1186/s12885-019-5952-2.

7.

Somatostatin receptor expression in parathyroid neoplasms.

Storvall S, Leijon H, Ryhänen E, Louhimo J, Haglund C, Schalin-Jäntti C, Arola J.

Endocr Connect. 2019 Jul 1. pii: EC-19-0260.R2. doi: 10.1530/EC-19-0260. [Epub ahead of print]

8.

Toll-like receptor 1 predicts favorable prognosis in pancreatic cancer.

Lanki M, Seppänen H, Mustonen H, Hagström J, Haglund C.

PLoS One. 2019 Jul 17;14(7):e0219245. doi: 10.1371/journal.pone.0219245. eCollection 2019.

9.

Optimization and Mechanistic Characterization of Pyridopyrimidine Inhibitors of Bacterial Biotin Carboxylase.

Andrews LD, Kane TR, Dozzo P, Haglund CM, Hilderbrandt DJ, Linsell MS, Machajewski T, McEnroe G, Serio AW, Wlasichuk KB, Neau DB, Pakhomova S, Waldrop GL, Sharp M, Pogliano J, Cirz RT, Cohen F.

J Med Chem. 2019 Aug 22;62(16):7489-7505. doi: 10.1021/acs.jmedchem.9b00625. Epub 2019 Aug 9.

PMID:
31306011
10.

PD-1 and PD-L1 expression in pulmonary carcinoid tumors and their association to tumor spread.

Vesterinen T, Kuopio T, Ahtiainen M, Knuuttila A, Mustonen H, Salmenkivi K, Arola J, Haglund C.

Endocr Connect. 2019 Aug 1;8(8):1168-1175. doi: 10.1530/EC-19-0308.

11.

Mesenchymal transition and increased therapy resistance of glioblastoma cells is related to astrocyte reactivity.

Niklasson M, Bergström T, Jarvius M, Sundström A, Nyberg F, Haglund C, Larsson R, Westermark B, Segerman B, Segerman A.

J Pathol. 2019 Jul 12. doi: 10.1002/path.5317. [Epub ahead of print]

PMID:
31298733
12.

Assessment of Tumor-infiltrating Lymphocytes Predicts the Behavior of Early-stage Oral Tongue Cancer.

Heikkinen I, Bello IO, Wahab A, Hagström J, Haglund C, Coletta RD, Nieminen P, Mäkitie AA, Salo T, Leivo I, Almangush A.

Am J Surg Pathol. 2019 Oct;43(10):1392-1396. doi: 10.1097/PAS.0000000000001323.

PMID:
31290758
13.

Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety.

Cohen F, Aggen JB, Andrews LD, Assar Z, Boggs J, Choi T, Dozzo P, Easterday AN, Haglund CM, Hildebrandt DJ, Holt MC, Joly K, Jubb A, Kamal Z, Kane TR, Konradi AW, Krause KM, Linsell MS, Machajewski TD, Miroshnikova O, Moser HE, Nieto V, Phan T, Plato C, Serio AW, Seroogy J, Shakhmin A, Stein AJ, Sun AD, Sviridov S, Wang Z, Wlasichuk K, Yang W, Zhou X, Zhu H, Cirz RT.

ChemMedChem. 2019 Aug 20;14(16):1560-1572. doi: 10.1002/cmdc.201900287. Epub 2019 Aug 5.

PMID:
31283109
14.

Mucin 16 and kallikrein 13 as potential prognostic factors in colon cancer: Results of an oncological 92-multiplex immunoassay.

Björkman K, Mustonen H, Kaprio T, Haglund C, Böckelman C.

Tumour Biol. 2019 Jul;41(7):1010428319860728. doi: 10.1177/1010428319860728.

PMID:
31264534
15.

Polyomavirus JCPyV infrequently detectable in adenoid cystic carcinoma of the oral cavity and the airways.

Hämetoja H, Hagström J, Haglund C, Bäck L, Mäkitie A, Syrjänen S.

Virchows Arch. 2019 Jul 1. doi: 10.1007/s00428-019-02617-6. [Epub ahead of print]

PMID:
31264036
16.

High levels of tissue inhibitor of metalloproteinase-1 (TIMP-1) in the serum are associated with poor prognosis in HPV-negative squamous cell oropharyngeal cancer.

Carpén T, Sorsa T, Jouhi L, Tervahartiala T, Haglund C, Syrjänen S, Tarkkanen J, Mohamed H, Mäkitie A, Hagström J, Mattila PS.

Cancer Immunol Immunother. 2019 Aug;68(8):1263-1272. doi: 10.1007/s00262-019-02362-4. Epub 2019 Jun 25.

17.

Expression of toll-like receptors in non-endemic nasopharyngeal carcinoma.

Ruuskanen M, Leivo I, Minn H, Vahlberg T, Haglund C, Hagström J, Irjala H.

BMC Cancer. 2019 Jun 25;19(1):624. doi: 10.1186/s12885-019-5816-9.

18.

In situ hybridization for high-risk HPV E6/E7 mRNA is a superior method for detecting transcriptionally active HPV in oropharyngeal cancer.

Randén-Brady R, Carpén T, Jouhi L, Syrjänen S, Haglund C, Tarkkanen J, Remes S, Mäkitie A, Mattila PS, Silén S, Hagström J.

Hum Pathol. 2019 Aug;90:97-105. doi: 10.1016/j.humpath.2019.05.006. Epub 2019 May 21.

PMID:
31121191
19.

Adrenocortical carcinoma: presentation and outcome of a contemporary patient series.

Kostiainen I, Hakaste L, Kejo P, Parviainen H, Laine T, Löyttyniemi E, Pennanen M, Arola J, Haglund C, Heiskanen I, Schalin-Jäntti C.

Endocrine. 2019 Jul;65(1):166-174. doi: 10.1007/s12020-019-01918-9. Epub 2019 Apr 12.

20.

The expression and prognostic value of stem cell markers Bmi-1, HESC5:3, and HES77 in human papillomavirus-positive and -negative oropharyngeal squamous cell carcinoma.

Mohamed H, Hagström J, Jouhi L, Atula T, Almangush A, Mäkitie A, Haglund C.

Tumour Biol. 2019 Mar;41(3):1010428319840473. doi: 10.1177/1010428319840473.

PMID:
30915904
21.

A Proposal to Revise the Histopathologic Grading System of Early Oral Tongue Cancer Incorporating Tumor Budding.

Elseragy A, Salo T, Coletta RD, Kowalski LP, Haglund C, Nieminen P, Mäkitie AA, Leivo I, Almangush A.

Am J Surg Pathol. 2019 May;43(5):703-709. doi: 10.1097/PAS.0000000000001241.

PMID:
30829728
22.

BRAF V600E expression in ameloblastomas-A 36-patient cohort from Helsinki University Hospital.

Kelppe J, Thorén H, Ristimäki A, Haglund C, Sorsa T, Hagström J.

Oral Dis. 2019 May;25(4):1169-1174. doi: 10.1111/odi.13072. Epub 2019 Mar 19.

PMID:
30811720
23.

TLR5 and TLR7 are differentially expressed in human papillomavirus-positive and negative base of tongue squamous cell carcinoma, and TLR7 may have an independent prognostic influence.

Haeggblom L, Näsman A, Ramqvist T, Haglund C, Hagström J, Mäkitie A, Dalianis T.

Acta Otolaryngol. 2019 Feb;139(2):206-210. doi: 10.1080/00016489.2018.1552014. Epub 2019 Feb 22.

PMID:
30794027
24.

Ornithine decarboxylase antizyme inhibitor 2 (AZIN2) is a signature of secretory phenotype and independent predictor of adverse prognosis in colorectal cancer.

Kaprio T, Rasila T, Hagström J, Mustonen H, Lankila P, Haglund C, Andersson LC.

PLoS One. 2019 Feb 15;14(2):e0211564. doi: 10.1371/journal.pone.0211564. eCollection 2019.

25.

Estrogen receptor beta expression correlates with proliferation in desmoid tumors.

Santti K, Ihalainen H, Rönty M, Karlsson C, Haglund C, Sampo M, Tarkkanen M, Blomqvist C.

J Surg Oncol. 2019 Jun;119(7):873-879. doi: 10.1002/jso.25407. Epub 2019 Feb 11.

PMID:
30742303
26.

Somatostatin Receptor Expression Is Associated With Metastasis and Patient Outcome in Pulmonary Carcinoid Tumors.

Vesterinen T, Leijon H, Mustonen H, Remes S, Knuuttila A, Salmenkivi K, Vainio P, Arola J, Haglund C.

J Clin Endocrinol Metab. 2019 Jun 1;104(6):2083-2093. doi: 10.1210/jc.2018-01931.

PMID:
30657933
27.

High serum MMP-14 predicts worse survival in gastric cancer.

Kasurinen A, Tervahartiala T, Laitinen A, Kokkola A, Sorsa T, Böckelman C, Haglund C.

PLoS One. 2018 Dec 7;13(12):e0208800. doi: 10.1371/journal.pone.0208800. eCollection 2018.

28.

Variable somatostatin receptor subtype expression in 151 primary pheochromocytomas and paragangliomas.

Leijon H, Remes S, Hagström J, Louhimo J, Mäenpää H, Schalin-Jäntti C, Miettinen M, Haglund C, Arola J.

Hum Pathol. 2019 Apr;86:66-75. doi: 10.1016/j.humpath.2018.11.020. Epub 2018 Dec 8.

29.

Label-free tissue proteomics can classify oral squamous cell carcinoma from healthy tissue in a stage-specific manner.

Dickinson A, Saraswat M, Mäkitie A, Silén R, Hagström J, Haglund C, Joenväärä S, Silén S.

Oral Oncol. 2018 Nov;86:206-215. doi: 10.1016/j.oraloncology.2018.09.013. Epub 2018 Oct 3.

PMID:
30409303
30.

Ameloblastoma: a retrospective single institute study of 34 subjects.

Kelppe J, Hagström J, Sorsa T, Suominen AL, Apajalahti S, Haglund C, Thorén H.

Acta Odontol Scand. 2018 Nov 7:1-6. doi: 10.1080/00016357.2018.1532530. [Epub ahead of print]

PMID:
30404552
31.

Combined epithelial marker analysis of tumour budding in stage II colorectal cancer.

Slik K, Blom S, Turkki R, Välimäki K, Kurki S, Mustonen H, Haglund C, Carpén O, Kallioniemi O, Korkeila E, Sundström J, Pellinen T.

J Pathol Clin Res. 2019 Jan;5(1):63-78. doi: 10.1002/cjp2.119. Epub 2018 Nov 29.

32.

Astroprincin (FAM171A1, C10orf38): A Regulator of Human Cell Shape and Invasive Growth.

Rasila T, Saavalainen O, Attalla H, Lankila P, Haglund C, Hölttä E, Andersson LC.

Am J Pathol. 2019 Jan;189(1):177-189. doi: 10.1016/j.ajpath.2018.09.006. Epub 2018 Oct 10.

33.

Toll-like receptor 2 and Toll-like receptor 4 predict favorable prognosis in local pancreatic cancer.

Lanki MA, Seppänen HE, Mustonen HK, Böckelman C, Juuti AT, Hagström JK, Haglund CH.

Tumour Biol. 2018 Sep;40(9):1010428318801188. doi: 10.1177/1010428318801188.

PMID:
30246618
34.

Serum MMP-8 and TIMP-1 as prognostic biomarkers in gastric cancer.

Laitinen A, Hagström J, Mustonen H, Kokkola A, Tervahartiala T, Sorsa T, Böckelman C, Haglund C.

Tumour Biol. 2018 Sep;40(9):1010428318799266. doi: 10.1177/1010428318799266.

PMID:
30192205
35.

Glycomic Profiling Highlights Increased Fucosylation in Pseudomyxoma Peritonei.

Saarinen L, Nummela P, Leinonen H, Heiskanen A, Thiel A, Haglund C, Lepistö A, Satomaa T, Hautaniemi S, Ristimäki A.

Mol Cell Proteomics. 2018 Nov;17(11):2107-2118. doi: 10.1074/mcp.RA118.000615. Epub 2018 Aug 2.

PMID:
30072579
36.

Small oral tongue cancers (≤ 4 cm in diameter) with clinically negative neck: from the 7th to the 8th edition of the American Joint Committee on Cancer.

Almangush A, Mäkitie AA, Mäkinen LK, Kauppila JH, Pukkila M, Hagström J, Laranne J, Soini Y, Kowalski LP, Grénman R, Haglund C, Coletta RD, Salo T, Leivo I.

Virchows Arch. 2018 Oct;473(4):481-487. doi: 10.1007/s00428-018-2417-y. Epub 2018 Jul 23.

PMID:
30039390
37.

The prognostic significance of tall cells in papillary thyroid carcinoma: A case-control study.

Stenman S, Siironen P, Mustonen H, Lundin J, Haglund C, Arola J.

Tumour Biol. 2018 Jul;40(7):1010428318787720. doi: 10.1177/1010428318787720.

PMID:
30010512
38.

PROX1 is a transcriptional regulator of MMP14.

Gramolelli S, Cheng J, Martinez-Corral I, Vähä-Koskela M, Elbasani E, Kaivanto E, Rantanen V, Tuohinto K, Hautaniemi S, Bower M, Haglund C, Alitalo K, Mäkinen T, Petrova TV, Lehti K, Ojala PM.

Sci Rep. 2018 Jun 22;8(1):9531. doi: 10.1038/s41598-018-27739-w.

39.

Treponema denticola chymotrypsin-like protease as associated with HPV-negative oropharyngeal squamous cell carcinoma.

Kylmä AK, Jouhi L, Listyarifah D, Mohamed H, Mäkitie A, Remes SM, Haglund C, Atula T, Nieminen MT, Sorsa T, Hagström J.

Br J Cancer. 2018 Jul;119(1):89-95. doi: 10.1038/s41416-018-0143-5. Epub 2018 Jun 22.

40.

Serum MMP-8 and TIMP-1 predict prognosis in colorectal cancer.

Böckelman C, Beilmann-Lehtonen I, Kaprio T, Koskensalo S, Tervahartiala T, Mustonen H, Stenman UH, Sorsa T, Haglund C.

BMC Cancer. 2018 Jun 22;18(1):679. doi: 10.1186/s12885-018-4589-x.

41.

High cyclin A expression, but not Ki67, is associated with early recurrence in desmoid tumors.

Santti K, Ihalainen H, Rönty M, Böhling T, Karlsson C, Haglund C, Tarkkanen M, Blomqvist C.

J Surg Oncol. 2018 Jul;118(1):192-198. doi: 10.1002/jso.25121. Epub 2018 Jun 7.

PMID:
29878366
42.

Preoperative Biomarker Panel, Including Fibrinogen and FVIII, Improves Diagnostic Accuracy for Pancreatic Ductal Adenocarcinoma.

Mattila N, Seppänen H, Mustonen H, Przybyla B, Haglund C, Lassila R.

Clin Appl Thromb Hemost. 2018 Nov;24(8):1267-1275. doi: 10.1177/1076029618779133. Epub 2018 Jun 4.

43.

Tumor volume as a prognostic marker in p16-positive and p16-negative oropharyngeal cancer patients treated with definitive intensity-modulated radiotherapy.

Carpén T, Saarilahti K, Haglund C, Markkola A, Tarkkanen J, Hagström J, Mattila P, Mäkitie A.

Strahlenther Onkol. 2018 Aug;194(8):759-770. doi: 10.1007/s00066-018-1309-z. Epub 2018 May 17.

PMID:
29774396
44.

Treponema denticola chymotrypsin-like proteinase is present in early-stage mobile tongue squamous cell carcinoma and related to the clinicopathological features.

Listyarifah D, Nieminen MT, Mäkinen LK, Haglund C, Grenier D, Häyry V, Nordström D, Hernandez M, Yucel-Lindberg T, Tervahartiala T, Ainola M, Sorsa T, Hagström J.

J Oral Pathol Med. 2018 Sep;47(8):764-772. doi: 10.1111/jop.12729. Epub 2018 May 27.

PMID:
29747237
45.

MMP-7 expression may influence the rate of distant recurrences and disease-specific survival in HPV-positive oropharyngeal squamous cell carcinoma.

Vento SI, Jouhi L, Mohamed H, Haglund C, Mäkitie AA, Atula T, Hagström J, Mäkinen LK.

Virchows Arch. 2018 Jun;472(6):975-981. doi: 10.1007/s00428-018-2365-6. Epub 2018 May 2.

PMID:
29721609
46.

Colorectal cancer patients with different C-reactive protein levels and 5-year survival times can be differentiated with quantitative serum proteomics.

Holm M, Saraswat M, Joenväärä S, Ristimäki A, Haglund C, Renkonen R.

PLoS One. 2018 Apr 9;13(4):e0195354. doi: 10.1371/journal.pone.0195354. eCollection 2018.

47.

Expression of hormone receptors in oropharyngeal squamous cell carcinoma.

Mohamed H, Aro K, Jouhi L, Mäkitie A, Remes S, Haglund C, Atula T, Hagström J.

Eur Arch Otorhinolaryngol. 2018 May;275(5):1289-1300. doi: 10.1007/s00405-018-4949-9. Epub 2018 Mar 26.

PMID:
29582173
48.

Prognostic and diagnostic value of REG4 serum and tissue expression in pancreatic ductal adenocarcinoma.

Saukkonen K, Hagström J, Mustonen H, Lehtinen L, Carpen O, Andersson LC, Seppänen H, Haglund C.

Tumour Biol. 2018 Mar;40(3):1010428318761494. doi: 10.1177/1010428318761494.

PMID:
29542402
49.

Positive cytoplasmic UCHL5 tumor expression in gastric cancer is linked to improved prognosis.

Arpalahti L, Laitinen A, Hagström J, Mustonen H, Kokkola A, Böckelman C, Haglund C, Holmberg CI.

PLoS One. 2018 Feb 23;13(2):e0193125. doi: 10.1371/journal.pone.0193125. eCollection 2018. Erratum in: PLoS One. 2018 May 2;13(5):e0197013.

50.

Deep learning based tissue analysis predicts outcome in colorectal cancer.

Bychkov D, Linder N, Turkki R, Nordling S, Kovanen PE, Verrill C, Walliander M, Lundin M, Haglund C, Lundin J.

Sci Rep. 2018 Feb 21;8(1):3395. doi: 10.1038/s41598-018-21758-3.

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