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Items: 1 to 50 of 464

1.

Deep Supervision with Intermediate Concepts.

Li C, Zia MZ, Tran QH, Yu X, Hager GD, Chandraker M.

IEEE Trans Pattern Anal Mach Intell. 2018 Aug 13. doi: 10.1109/TPAMI.2018.2863285. [Epub ahead of print]

PMID:
30106706
2.

Evaluation and Stability Analysis of Video-Based Navigation System for Functional Endoscopic Sinus Surgery on In-Vivo Clinical Data.

Leonard S, Sinha A, Reiter A, Ishii M, Gallia GL, Taylor RH, Hager GD.

IEEE Trans Med Imaging. 2018 May 7. doi: 10.1109/TMI.2018.2833868. [Epub ahead of print]

PMID:
29993881
3.

Dual Roles for Ikaros in Regulation of Macrophage Chromatin State and Inflammatory Gene Expression.

Oh KS, Gottschalk RA, Lounsbury NW, Sun J, Dorrington MG, Baek S, Sun G, Wang Z, Krauss KS, Milner JD, Dutta B, Hager GL, Sung MH, Fraser IDC.

J Immunol. 2018 Jul 15;201(2):757-771. doi: 10.4049/jimmunol.1800158. Epub 2018 Jun 13.

PMID:
29898962
4.

The role of protein methyltransferases as potential novel therapeutic targets in squamous cell carcinoma of the head and neck.

Saloura V, Vougiouklakis T, Sievers C, Burkitt K, Nakamura Y, Hager G, van Waes C.

Oral Oncol. 2018 Jun;81:100-108. doi: 10.1016/j.oraloncology.2018.04.014. Epub 2018 May 3. Review.

5.

Chromatin reprogramming in breast cancer.

Swinstead EE, Paakinaho V, Hager GL.

Endocr Relat Cancer. 2018 Jul;25(7):R385-R404. doi: 10.1530/ERC-18-0033. Epub 2018 Apr 24. Review.

6.

Synergistic gene expression during the acute phase response is characterized by transcription factor assisted loading.

Goldstein I, Paakinaho V, Baek S, Sung MH, Hager GL.

Nat Commun. 2017 Nov 29;8(1):1849. doi: 10.1038/s41467-017-02055-5.

7.

Conventional and pioneer modes of glucocorticoid receptor interaction with enhancer chromatin in vivo.

Johnson TA, Chereji RV, Stavreva DA, Morris SA, Hager GL, Clark DJ.

Nucleic Acids Res. 2018 Jan 9;46(1):203-214. doi: 10.1093/nar/gkx1044.

8.

The Three Ds of Transcription Activation by Glucagon: Direct, Delayed, and Dynamic.

Goldstein I, Hager GL.

Endocrinology. 2018 Jan 1;159(1):206-216. doi: 10.1210/en.2017-00521. Review.

PMID:
29077799
9.

Surgical data science: The new knowledge domain.

Vedula SS, Hager GD.

Innov Surg Sci. 2017 Apr;2(3):109-121. doi: 10.1515/iss-2017-0004. Epub 2017 Apr 20.

10.

Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation.

Kieffer-Kwon KR, Nimura K, Rao SSP, Xu J, Jung S, Pekowska A, Dose M, Stevens E, Mathe E, Dong P, Huang SC, Ricci MA, Baranello L, Zheng Y, Tomassoni Ardori F, Resch W, Stavreva D, Nelson S, McAndrew M, Casellas A, Finn E, Gregory C, St Hilaire BG, Johnson SM, Dubois W, Cosma MP, Batchelor E, Levens D, Phair RD, Misteli T, Tessarollo L, Hager G, Lakadamyali M, Liu Z, Floer M, Shroff H, Aiden EL, Casellas R.

Mol Cell. 2017 Aug 17;67(4):566-578.e10. doi: 10.1016/j.molcel.2017.07.013. Epub 2017 Aug 10.

11.

Anti-Inflammatory Chromatinscape Suggests Alternative Mechanisms of Glucocorticoid Receptor Action.

Oh KS, Patel H, Gottschalk RA, Lee WS, Baek S, Fraser IDC, Hager GL, Sung MH.

Immunity. 2017 Aug 15;47(2):298-309.e5. doi: 10.1016/j.immuni.2017.07.012. Epub 2017 Aug 8.

12.

Determination of uranium isotope ratios using a liquid sampling atmospheric pressure glow discharge/Orbitrap mass spectrometer system.

Hoegg ED, Marcus RK, Koppenaal DW, Irvahn J, Hager GJ, Hart GL.

Rapid Commun Mass Spectrom. 2017 Sep 30;31(18):1534-1540. doi: 10.1002/rcm.7937.

PMID:
28696545
13.

Single-molecule analysis of steroid receptor and cofactor action in living cells.

Paakinaho V, Presman DM, Ball DA, Johnson TA, Schiltz RL, Levitt P, Mazza D, Morisaki T, Karpova TS, Hager GL.

Nat Commun. 2017 Jun 21;8:15896. doi: 10.1038/ncomms15896.

14.

Dynamic enhancer function in the chromatin context.

Goldstein I, Hager GL.

Wiley Interdiscip Rev Syst Biol Med. 2018 Jan;10(1). doi: 10.1002/wsbm.1390. Epub 2017 May 22. Review.

PMID:
28544514
15.

Bivariate Genomic Footprinting Detects Changes in Transcription Factor Activity.

Baek S, Goldstein I, Hager GL.

Cell Rep. 2017 May 23;19(8):1710-1722. doi: 10.1016/j.celrep.2017.05.003.

16.

Identifying environmental chemicals as agonists of the androgen receptor by using a quantitative high-throughput screening platform.

Lynch C, Sakamuru S, Huang R, Stavreva DA, Varticovski L, Hager GL, Judson RS, Houck KA, Kleinstreuer NC, Casey W, Paules RS, Simeonov A, Xia M.

Toxicology. 2017 Jun 15;385:48-58. doi: 10.1016/j.tox.2017.05.001. Epub 2017 May 4.

PMID:
28478275
17.

Objective Assessment of Surgical Technical Skill and Competency in the Operating Room.

Vedula SS, Ishii M, Hager GD.

Annu Rev Biomed Eng. 2017 Jun 21;19:301-325. doi: 10.1146/annurev-bioeng-071516-044435. Epub 2017 Mar 27. Review.

18.

Quantifying transcription factor binding dynamics at the single-molecule level in live cells.

Presman DM, Ball DA, Paakinaho V, Grimm JB, Lavis LD, Karpova TS, Hager GL.

Methods. 2017 Jul 1;123:76-88. doi: 10.1016/j.ymeth.2017.03.014. Epub 2017 Mar 15.

19.

Genome-Wide Identification of Basic Helix-Loop-Helix and NF-1 Motifs Underlying GR Binding Sites in Male Rat Hippocampus.

Pooley JR, Flynn BP, Grøntved L, Baek S, Guertin MJ, Kershaw YM, Birnie MT, Pellatt A, Rivers CA, Schiltz RL, Hager GL, Lightman SL, Conway-Campbell BL.

Endocrinology. 2017 May 1;158(5):1486-1501. doi: 10.1210/en.2016-1929.

20.

Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma.

Veschi V, Liu Z, Voss TC, Ozbun L, Gryder B, Yan C, Hu Y, Ma A, Jin J, Mazur SJ, Lam N, Souza BK, Giannini G, Hager GL, Arrowsmith CH, Khan J, Appella E, Thiele CJ.

Cancer Cell. 2017 Jan 9;31(1):50-63. doi: 10.1016/j.ccell.2016.12.002.

21.

High fat diet-induced changes of mouse hepatic transcription and enhancer activity can be reversed by subsequent weight loss.

Siersbæk M, Varticovski L, Yang S, Baek S, Nielsen R, Mandrup S, Hager GL, Chung JH, Grøntved L.

Sci Rep. 2017 Jan 10;7:40220. doi: 10.1038/srep40220.

22.

A Dataset and Benchmarks for Segmentation and Recognition of Gestures in Robotic Surgery.

Ahmidi N, Tao L, Sefati S, Gao Y, Lea C, Haro BB, Zappella L, Khudanpur S, Vidal R, Hager GD.

IEEE Trans Biomed Eng. 2017 Sep;64(9):2025-2041. doi: 10.1109/TBME.2016.2647680. Epub 2017 Jan 4.

PMID:
28060703
23.

Transcription factor assisted loading and enhancer dynamics dictate the hepatic fasting response.

Goldstein I, Baek S, Presman DM, Paakinaho V, Swinstead EE, Hager GL.

Genome Res. 2017 Mar;27(3):427-439. doi: 10.1101/gr.212175.116. Epub 2016 Dec 28.

24.

Nonclinical Safety Testing of RNA Vaccines.

Hager G.

Methods Mol Biol. 2017;1499:253-272. Review.

PMID:
27987155
25.
26.

Cajal body function in genome organization and transcriptome diversity.

Sawyer IA, Sturgill D, Sung MH, Hager GL, Dundr M.

Bioessays. 2016 Dec;38(12):1197-1208. doi: 10.1002/bies.201600144. Epub 2016 Oct 21. Review.

27.

More than meets the dimer: What is the quaternary structure of the glucocorticoid receptor?

Presman DM, Hager GL.

Transcription. 2017 Jan;8(1):32-39. doi: 10.1080/21541264.2016.1249045. Epub 2016 Oct 20.

28.

Novel cell-based assay for detection of thyroid receptor beta-interacting environmental contaminants.

Stavreva DA, Varticovski L, Levkova L, George AA, Davis L, Pegoraro G, Blazer V, Iwanowicz L, Hager GL.

Toxicology. 2016 Aug 10;368-369:69-79. doi: 10.1016/j.tox.2016.08.012. Epub 2016 Aug 12.

29.

Specific genomic cues regulate Cajal body assembly.

Sawyer IA, Hager GL, Dundr M.

RNA Biol. 2017 Jun 3;14(6):791-803. doi: 10.1080/15476286.2016.1243648. Epub 2016 Oct 7. Review.

30.

Anatomically Constrained Video-CT Registration via the V-IMLOP Algorithm.

Billings SD, Sinha A, Reiter A, Leonard S, Ishii M, Hager GD, Taylor RH.

Med Image Comput Comput Assist Interv. 2016 Oct;9902:133-141. doi: 10.1007/978-3-319-46726-9_16. Epub 2016 Oct 2.

31.

Warm-Up Before Robotic Hysterectomy Does Not Improve Trainee Operative Performance: A Randomized Trial.

Chen C, Tanner E, Malpani A, Vedula SS, Fader AN, Scheib SA, Green IC, Hager GD.

J Minim Invasive Gynecol. 2015 Nov-Dec;22(6S):S34. doi: 10.1016/j.jmig.2015.08.093. Epub 2015 Oct 15. No abstract available.

PMID:
27679212
32.

Discriminative Scale Space Tracking.

Danelljan M, Hager G, Khan FS, Felsberg M.

IEEE Trans Pattern Anal Mach Intell. 2017 Aug;39(8):1561-1575. doi: 10.1109/TPAMI.2016.2609928. Epub 2016 Sep 15.

PMID:
27654137
33.

AID/APOBEC-network reconstruction identifies pathways associated with survival in ovarian cancer.

Svoboda M, Meshcheryakova A, Heinze G, Jaritz M, Pils D, Castillo-Tong DC, Hager G, Thalhammer T, Jensen-Jarolim E, Birner P, Braicu I, Sehouli J, Lambrechts S, Vergote I, Mahner S, Zimmermann P, Zeillinger R, Mechtcheriakova D.

BMC Genomics. 2016 Aug 16;17(1):643. doi: 10.1186/s12864-016-3001-y.

34.

Guest Editorial: Special Section on CVPR 2013.

Freeman WT, Szeliski R, Hager GD.

IEEE Trans Pattern Anal Mach Intell. 2016 Apr;38(4):625-6. No abstract available.

PMID:
27403473
35.

DNA binding triggers tetramerization of the glucocorticoid receptor in live cells.

Presman DM, Ganguly S, Schiltz RL, Johnson TA, Karpova TS, Hager GL.

Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8236-41. doi: 10.1073/pnas.1606774113. Epub 2016 Jul 5.

36.

System events: readily accessible features for surgical phase detection.

Malpani A, Lea C, Chen CC, Hager GD.

Int J Comput Assist Radiol Surg. 2016 Jun;11(6):1201-9. doi: 10.1007/s11548-016-1409-0. Epub 2016 May 13.

PMID:
27177760
37.

Preliminary Figures of Merit for Isotope Ratio Measurements: The Liquid Sampling-Atmospheric Pressure Glow Discharge Microplasma Ionization Source Coupled to an Orbitrap Mass Analyzer.

Hoegg ED, Barinaga CJ, Hager GJ, Hart GL, Koppenaal DW, Marcus RK.

J Am Soc Mass Spectrom. 2016 Aug;27(8):1393-403. doi: 10.1007/s13361-016-1402-4. Epub 2016 Apr 14.

PMID:
27080006
38.

Query-by-example surgical activity detection.

Gao Y, Vedula SS, Lee GI, Lee MR, Khudanpur S, Hager GD.

Int J Comput Assist Radiol Surg. 2016 Jun;11(6):987-96. doi: 10.1007/s11548-016-1386-3. Epub 2016 Apr 12.

PMID:
27072835
39.

Steroid Receptors Reprogram FoxA1 Occupancy through Dynamic Chromatin Transitions.

Swinstead EE, Miranda TB, Paakinaho V, Baek S, Goldstein I, Hawkins M, Karpova TS, Ball D, Mazza D, Lavis LD, Grimm JB, Morisaki T, Grøntved L, Presman DM, Hager GL.

Cell. 2016 Apr 21;165(3):593-605. doi: 10.1016/j.cell.2016.02.067. Epub 2016 Apr 7.

40.

Divergent Binding and Transactivation by Two Related Steroid Receptors at the Same Response Element.

Tesikova M, Dezitter X, Nenseth HZ, Klokk TI, Mueller F, Hager GL, Saatcioglu F.

J Biol Chem. 2016 May 27;291(22):11899-910. doi: 10.1074/jbc.M115.684480. Epub 2016 Apr 7.

41.

Cajal bodies are linked to genome conformation.

Wang Q, Sawyer IA, Sung MH, Sturgill D, Shevtsov SP, Pegoraro G, Hakim O, Baek S, Hager GL, Dundr M.

Nat Commun. 2016 Mar 21;7:10966. doi: 10.1038/ncomms10966.

42.

Analysis of the Structure of Surgical Activity for a Suturing and Knot-Tying Task.

Vedula SS, Malpani AO, Tao L, Chen G, Gao Y, Poddar P, Ahmidi N, Paxton C, Vidal R, Khudanpur S, Hager GD, Chen CC.

PLoS One. 2016 Mar 7;11(3):e0149174. doi: 10.1371/journal.pone.0149174. eCollection 2016.

43.

Genome-wide footprinting: ready for prime time?

Sung MH, Baek S, Hager GL.

Nat Methods. 2016 Mar;13(3):222-228. doi: 10.1038/nmeth.3766.

44.

Task-Level vs. Segment-Level Quantitative Metrics for Surgical Skill Assessment.

Vedula SS, Malpani A, Ahmidi N, Khudanpur S, Hager G, Chen CC.

J Surg Educ. 2016 May-Jun;73(3):482-9. doi: 10.1016/j.jsurg.2015.11.009. Epub 2016 Feb 16.

PMID:
26896147
45.

Genome-Wide Chromatin Landscape Transitions Identify Novel Pathways in Early Commitment to Osteoblast Differentiation.

Thompson B, Varticovski L, Baek S, Hager GL.

PLoS One. 2016 Feb 18;11(2):e0148619. doi: 10.1371/journal.pone.0148619. eCollection 2016.

46.

Automatic segmentation and statistical shape modeling of the paranasal sinuses to estimate natural variations.

Sinha A, Leonard S, Reiter A, Ishii M, Taylor RH, Hager GD.

Proc SPIE Int Soc Opt Eng. 2016 Feb-Mar;9784. pii: 97840D. doi: 10.1117/12.2217337. Epub 2016 Mar 21.

47.

Image-Based Navigation for Functional Endoscopic Sinus Surgery Using Structure From Motion.

Leonard S, Reiter A, Sinha A, Ishii M, Taylor RH, Hager GD.

Proc SPIE Int Soc Opt Eng. 2016 Feb-Mar;9784. pii: 97840V. doi: 10.1117/12.2217279. Epub 2016 Mar 21.

48.

Endoscopic-CT: Learning-Based Photometric Reconstruction for Endoscopic Sinus Surgery.

Reiter A, Leonard S, Sinha A, Ishii M, Taylor RH, Hager GD.

Proc SPIE Int Soc Opt Eng. 2016 Feb-Mar;9784. pii: 978418. doi: 10.1117/12.2216296. Epub 2016 Mar 21.

49.

Chromatin structure and gene regulation: a dynamic view of enhancer function.

Stavreva DA, Hager GL.

Nucleus. 2015;6(6):442-8. doi: 10.1080/19491034.2015.1107689. Epub 2016 Jan 14.

50.

Transcriptional and Chromatin Regulation during Fasting - The Genomic Era.

Goldstein I, Hager GL.

Trends Endocrinol Metab. 2015 Dec;26(12):699-710. doi: 10.1016/j.tem.2015.09.005. Epub 2015 Oct 29. Review.

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