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Impulse for animal welfare outside the experiment.

Lewejohann L, Schwabe K, Häger C, Jirkof P.

Lab Anim. 2020 Feb 12:23677219891754. doi: 10.1177/0023677219891754. [Epub ahead of print]


Contactless Anesthesia Monitoring in Spontanously Breathing Rodents.

Kunczik J, Pereira CB, Wassermann L, Hager C, Bleich A, Zieglowski L, Tolba R, Czaplik M.

Conf Proc IEEE Eng Med Biol Soc. 2019 Jul;2019:6077-6080. doi: 10.1109/EMBC.2019.8856869.


A novel test reliably captures hip and knee kinematics and kinetics during unanticipated/anticipated diagonal hops in individuals with anterior cruciate ligament reconstruction.

Arumugam A, Markström JL, Häger CK.

J Biomech. 2020 Jan 23;99:109480. doi: 10.1016/j.jbiomech.2019.109480. Epub 2019 Nov 2.


Where are we heading? Challenges in evidence-based severity assessment.

Keubler LM, Hoppe N, Potschka H, Talbot SR, Vollmar B, Zechner D, Häger C, Bleich A.

Lab Anim. 2020 Feb;54(1):50-62. doi: 10.1177/0023677219877216. Epub 2019 Nov 13.


A safe bet? Inter-laboratory variability in behaviour-based severity assessment.

Jirkof P, Abdelrahman A, Bleich A, Durst M, Keubler L, Potschka H, Struve B, Talbot SR, Vollmar B, Zechner D, Häger C.

Lab Anim. 2020 Feb;54(1):73-82. doi: 10.1177/0023677219881481. Epub 2019 Nov 7.


The Apoptosis Pathway and CASP8 Variants Conferring Risk for Acute and Overuse Musculoskeletal Injuries.

Seale K, Burger M, Posthumus M, Häger CK, Stattin E, Nilsson KG, Collins M, September AV.

J Orthop Res. 2020 Mar;38(3):680-688. doi: 10.1002/jor.24504. Epub 2019 Nov 11.


Wheel running behaviour in group-housed female mice indicates disturbed wellbeing due to DSS colitis.

Weegh N, Füner J, Janke O, Winter Y, Jung C, Struve B, Wassermann L, Lewejohann L, Bleich A, Häger C.

Lab Anim. 2020 Feb;54(1):63-72. doi: 10.1177/0023677219879455. Epub 2019 Nov 1.


Kinematic analyses including finite helical axes of drop jump landings demonstrate decreased knee control long after anterior cruciate ligament injury.

Grip H, Tengman E, Liebermann DG, Häger CK.

PLoS One. 2019 Oct 31;14(10):e0224261. doi: 10.1371/journal.pone.0224261. eCollection 2019.


Defining body-weight reduction as a humane endpoint: a critical appraisal.

Talbot SR, Biernot S, Bleich A, van Dijk RM, Ernst L, Häger C, Helgers SOA, Koegel B, Koska I, Kuhla A, Miljanovic N, Müller-Graff FT, Schwabe K, Tolba R, Vollmar B, Weegh N, Wölk T, Wolf F, Wree A, Zieglowski L, Potschka H, Zechner D.

Lab Anim. 2020 Feb;54(1):99-110. doi: 10.1177/0023677219883319. Epub 2019 Oct 30.


Semi-automated generation of pictures for the Mouse Grimace Scale: A multi-laboratory analysis (Part 2).

Ernst L, Kopaczka M, Schulz M, Talbot SR, Struve B, Häger C, Bleich A, Durst M, Jirkof P, Arras M, van Dijk RM, Miljanovic N, Potschka H, Merhof D, Tolba RH.

Lab Anim. 2020 Feb;54(1):92-98. doi: 10.1177/0023677219881664. Epub 2019 Oct 29.


One-leg rise performance and associated knee kinematics in ACL-deficient and ACL-reconstructed persons 23 years post-injury.

Strong A, Tengman E, Srinivasan D, Häger CK.

BMC Musculoskelet Disord. 2019 Oct 25;20(1):476. doi: 10.1186/s12891-019-2887-3.


Systematic analysis of severity in a widely used cognitive depression model for mice.

Mallien AS, Häger C, Palme R, Talbot SR, Vogt MA, Pfeiffer N, Brandwein C, Struve B, Inta D, Chourbaji S, Hellweg R, Vollmayr B, Bleich A, Gass P.

Lab Anim. 2020 Feb;54(1):40-49. doi: 10.1177/0023677219874831. Epub 2019 Oct 1.


Activity of a novel 1,3-beta-D-glucan Synthase Inhibitor, Ibrexafungerp (formerly SCY-078), Against Candida glabrata.

Ghannoum M, Long L, Isham N, Hager C, Wilson R, Borroto-Esoda K, Barat S, Angulo D.

Antimicrob Agents Chemother. 2019 Sep 30. pii: AAC.01510-19. doi: 10.1128/AAC.01510-19. [Epub ahead of print]


Remote vitals monitoring in rodents using video recordings.

Kunczik J, Barbosa Pereira C, Zieglowski L, Tolba R, Wassermann L, Häger C, Bleich A, Janssen H, Thum T, Czaplik M.

Biomed Opt Express. 2019 Aug 5;10(9):4422-4436. doi: 10.1364/BOE.10.004422. eCollection 2019 Sep 1.


Functional polymorphisms within the inflammatory pathway regulate expression of extracellular matrix components in a genetic risk dependent model for anterior cruciate ligament injuries.

Suijkerbuijk MAM, Ponzetti M, Rahim M, Posthumus M, Häger CK, Stattin E, Nilsson KG, Teti A, Meuffels DE, van der Eerden BJC, Collins M, September AV.

J Sci Med Sport. 2019 Nov;22(11):1219-1225. doi: 10.1016/j.jsams.2019.07.012. Epub 2019 Jul 29.


FGF-2 isoforms influence the development of dopaminergic neurons in the murine substantia nigra, but not anxiety-like behavior, stress susceptibility, or locomotor behavior.

Hövel FFV, Leiter I, Rumpel R, Langenhagen A, Wedekind D, Häger C, Bleich A, Palme R, Grothe C.

Behav Brain Res. 2019 Nov 18;374:112113. doi: 10.1016/j.bbr.2019.112113. Epub 2019 Aug 2.


Jaw-neck movement integration in 6-year-old children differs from that of adults.

Österlund C, Nilsson E, Hellström F, Häger CK, Häggman-Henrikson B.

J Oral Rehabil. 2020 Jan;47(1):27-35. doi: 10.1111/joor.12865. Epub 2019 Aug 23.


Does the Femoral Head Size in Hip Arthroplasty Influence Lower Body Movements during Squats, Gait and Stair Walking? A Clinical Pilot Study Based on Wearable Motion Sensors.

Grip H, Nilsson KG, Häger CK, Lundström R, Öhberg F.

Sensors (Basel). 2019 Jul 23;19(14). pii: E3240. doi: 10.3390/s19143240.


Nest-building performance in rats: impact of vendor, experience, and sex.

Schwabe K, Boldt L, Bleich A, van Dijk RM, Helgers SOA, Häger C, Nowakowska M, Riedesel AK, Schönhoff K, Struve B, Wittek J, Potschka H.

Lab Anim. 2020 Feb;54(1):17-25. doi: 10.1177/0023677219862004. Epub 2019 Jul 23.


Dynamic knee control and movement strategies in athletes and non-athletes in side hops: Implications for knee injury.

Markström JL, Grip H, Schelin L, Häger CK.

Scand J Med Sci Sports. 2019 Aug;29(8):1181-1189. doi: 10.1111/sms.13432. Epub 2019 Apr 25.


Effects of a Novel Probiotic Combination on Pathogenic Bacterial-Fungal Polymicrobial Biofilms.

Hager CL, Isham N, Schrom KP, Chandra J, McCormick T, Miyagi M, Ghannoum MA.

mBio. 2019 Apr 2;10(2). pii: e00338-19. doi: 10.1128/mBio.00338-19.


Fungal Translocation Is Associated with Immune Activation and Systemic Inflammation in Treated HIV.

Weiner LD, Retuerto M, Hager CL, El Kamari V, Shan L, Sattar A, Kulkarni M, Funderburg N, Ghannoum MA, Dirajlal-Fargo S, McComsey GA.

AIDS Res Hum Retroviruses. 2019 May;35(5):461-472. doi: 10.1089/AID.2018.0252. Epub 2019 Apr 4.


A modified standardized nine hole peg test for valid and reliable kinematic assessment of dexterity post-stroke.

Johansson GM, Häger CK.

J Neuroeng Rehabil. 2019 Jan 14;16(1):8. doi: 10.1186/s12984-019-0479-y.


A novel standardised side hop test reliably evaluates landing mechanics for anterior cruciate ligament reconstructed persons and controls.

Markström JL, Schelin L, Häger CK.

Sports Biomech. 2018 Dec 10:1-17. doi: 10.1080/14763141.2018.1538385. [Epub ahead of print]


Introducing a novel test with unanticipated medial/lateral diagonal hops that reliably captures hip and knee kinematics in healthy women.

Arumugam A, Markström JL, Häger CK.

J Biomech. 2019 Jan 3;82:70-79. doi: 10.1016/j.jbiomech.2018.10.015. Epub 2018 Oct 25.


Running in the wheel: Defining individual severity levels in mice.

Häger C, Keubler LM, Talbot SR, Biernot S, Weegh N, Buchheister S, Buettner M, Glage S, Bleich A.

PLoS Biol. 2018 Oct 18;16(10):e2006159. doi: 10.1371/journal.pbio.2006159. eCollection 2018 Oct.


Small-molecule AgrA inhibitors F12 and F19 act as antivirulence agents against Gram-positive pathogens.

Greenberg M, Kuo D, Jankowsky E, Long L, Hager C, Bandi K, Ma D, Manoharan D, Shoham Y, Harte W, Ghannoum MA, Shoham M.

Sci Rep. 2018 Oct 1;8(1):14578. doi: 10.1038/s41598-018-32829-w.


Timing Training in Female Soccer Players: Effects on Skilled Movement Performance and Brain Responses.

Sommer M, Häger CK, Boraxbekk CJ, Rönnqvist L.

Front Hum Neurosci. 2018 Aug 2;12:311. doi: 10.3389/fnhum.2018.00311. eCollection 2018.


Evaluation of the efficacy of rezafungin, a novel echinocandin, in the treatment of disseminated Candida auris infection using an immunocompromised mouse model.

Hager CL, Larkin EL, Long LA, Ghannoum MA.

J Antimicrob Chemother. 2018 Aug 1;73(8):2085-2088. doi: 10.1093/jac/dky153.


Brief Report: Circulating Markers of Immunologic Activity Reflect Adiposity in Persons With HIV on Antiretroviral Therapy.

Koethe JR, Jenkins CA, Furch BD, Lake JE, Barnett L, Hager CC, Smith R, Hulgan T, Shepherd BE, Kalams SA.

J Acquir Immune Defic Syndr. 2018 Sep 1;79(1):135-140. doi: 10.1097/QAI.0000000000001768.


Impact of heat stress during the follicular phase on porcine ovarian steroidogenic and phosphatidylinositol-3 signaling.

Dickson MJ, Hager CL, Al-Shaibi A, Thomas PQ, Baumgard LH, Ross JW, Keating AF.

J Anim Sci. 2018 Jun 4;96(6):2162-2174. doi: 10.1093/jas/sky144.


Office-Cycling: A Promising Way to Raise Pain Thresholds and Increase Metabolism with Minimal Compromising of Work Performance.

Tronarp R, Nyberg A, Hedlund M, Häger CK, McDonough S, Björklund M.

Biomed Res Int. 2018 Jan 23;2018:5427201. doi: 10.1155/2018/5427201. eCollection 2018.


Impact of Workplace Exposure and Stress on Neck Pain and Disabilities in Women-A Longitudinal Follow-up After a Rehabilitation Intervention.

Svedmark Å, Björklund M, Häger CK, Sommar JN, Wahlström J.

Ann Work Expo Health. 2018 May 28;62(5):591-603. doi: 10.1093/annweh/wxy018.


Curve analyses reveal altered knee, hip, and trunk kinematics during drop-jumps long after anterior cruciate ligament rupture.

Hébert-Losier K, Schelin L, Tengman E, Strong A, Häger CK.

Knee. 2018 Mar;25(2):226-239. doi: 10.1016/j.knee.2017.12.005. Epub 2018 Mar 7.


Increased movement variability in one-leg hops about 20 years after treatment of anterior cruciate ligament injury.

Srinivasan D, Tengman E, Häger CK.

Clin Biomech (Bristol, Avon). 2018 Mar;53:37-45. doi: 10.1016/j.clinbiomech.2018.02.003. Epub 2018 Feb 6.


In Vitro and In Vivo Evaluation of the Antifungal Activity of APX001A/APX001 against Candida auris.

Hager CL, Larkin EL, Long L, Zohra Abidi F, Shaw KJ, Ghannoum MA.

Antimicrob Agents Chemother. 2018 Feb 23;62(3). pii: e02319-17. doi: 10.1128/AAC.02319-17. Print 2018 Mar.


The chemokine receptor CX3CR1 coordinates monocyte recruitment and endothelial regeneration after arterial injury.

Getzin T, Krishnasamy K, Gamrekelashvili J, Kapanadze T, Limbourg A, Häger C, Napp LC, Bauersachs J, Haller H, Limbourg FP.

EMBO Mol Med. 2018 Feb;10(2):151-159. doi: 10.15252/emmm.201707502.


Adipose Tissue is Enriched for Activated and Late-Differentiated CD8+ T Cells and Shows Distinct CD8+ Receptor Usage, Compared With Blood in HIV-Infected Persons.

Koethe JR, McDonnell W, Kennedy A, Abana CO, Pilkinton M, Setliff I, Georgiev I, Barnett L, Hager CC, Smith R, Kalams SA, Hasty A, Mallal S.

J Acquir Immune Defic Syndr. 2018 Feb 1;77(2):e14-e21. doi: 10.1097/QAI.0000000000001573.


Blood vessel control of macrophage maturation promotes arteriogenesis in ischemia.

Krishnasamy K, Limbourg A, Kapanadze T, Gamrekelashvili J, Beger C, Häger C, Lozanovski VJ, Falk CS, Napp LC, Bauersachs J, Mack M, Haller H, Weber C, Adams RH, Limbourg FP.

Nat Commun. 2017 Oct 16;8(1):952. doi: 10.1038/s41467-017-00953-2.


The mycobiome in HIV.

Hager CL, Ghannoum MA.

Curr Opin HIV AIDS. 2018 Jan;13(1):69-72. doi: 10.1097/COH.0000000000000432. Review.


Heat stress induces autophagy in pig ovaries during follicular development.

Hale BJ, Hager CL, Seibert JT, Selsby JT, Baumgard LH, Keating AF, Ross JW.

Biol Reprod. 2017 Sep 1;97(3):426-437. doi: 10.1093/biolre/iox097.


The mycobiome: Role in health and disease, and as a potential probiotic target in gastrointestinal disease.

Hager CL, Ghannoum MA.

Dig Liver Dis. 2017 Nov;49(11):1171-1176. doi: 10.1016/j.dld.2017.08.025. Epub 2017 Oct 4. Review.


Cytomegalovirus (CMV) Epitope-Specific CD4+ T Cells Are Inflated in HIV+ CMV+ Subjects.

Abana CO, Pilkinton MA, Gaudieri S, Chopra A, McDonnell WJ, Wanjalla C, Barnett L, Gangula R, Hager C, Jung DK, Engelhardt BG, Jagasia MH, Klenerman P, Phillips EJ, Koelle DM, Kalams SA, Mallal SA.

J Immunol. 2017 Nov 1;199(9):3187-3201. doi: 10.4049/jimmunol.1700851. Epub 2017 Oct 2.


Double-Sided Mechanical Shocks Provoke Larger Seated Postural Reactions Compared With Single-Sided Mechanical Shocks.

Stenlund TC, Öhberg F, Lundström R, Lindroos O, Häger CK, Neely G, Rehn B.

Spine (Phila Pa 1976). 2018 Apr 15;43(8):E482-E487. doi: 10.1097/BRS.0000000000002396.


Corrigendum: Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.

Gamrekelashvili J, Giagnorio R, Jussofie J, Soehnlein O, Duchene J, Briseño CG, Ramasamy SK, Krishnasamy K, Limbourg A, Häger C, Kapanadze T, Ishifune C, Hinkel R, Radtke F, Strobl LJ, Zimber-Strobl U, Napp LC, Bauersachs J, Haller H, Yasutomo K, Kupatt C, Murphy KM, Adams RH, Weber C, Limbourg FP.

Nat Commun. 2017 May 3;8:15486. doi: 10.1038/ncomms15486. No abstract available.


A statistically compiled test battery for feasible evaluation of knee function after rupture of the Anterior Cruciate Ligament - derived from long-term follow-up data.

Schelin L, Tengman E, Ryden P, Häger C.

PLoS One. 2017 May 1;12(5):e0176247. doi: 10.1371/journal.pone.0176247. eCollection 2017.


The importance of international collaboration for rare diseases research: a European perspective.

Julkowska D, Austin CP, Cutillo CM, Gancberg D, Hager C, Halftermeyer J, Jonker AH, Lau LPL, Norstedt I, Rath A, Schuster R, Simelyte E, van Weely S.

Gene Ther. 2017 Sep;24(9):562-571. doi: 10.1038/gt.2017.29. Epub 2017 Jul 27. Review.


The Sheep Grimace Scale as an indicator of post-operative distress and pain in laboratory sheep.

Häger C, Biernot S, Buettner M, Glage S, Keubler LM, Held N, Bleich EM, Otto K, Müller CW, Decker S, Talbot SR, Bleich A.

PLoS One. 2017 Apr 19;12(4):e0175839. doi: 10.1371/journal.pone.0175839. eCollection 2017.


ACL-reconstructed and ACL-deficient individuals show differentiated trunk, hip, and knee kinematics during vertical hops more than 20 years post-injury.

Markström JL, Tengman E, Häger CK.

Knee Surg Sports Traumatol Arthrosc. 2018 Feb;26(2):358-367. doi: 10.1007/s00167-017-4528-4. Epub 2017 Mar 23.

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