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Items: 40

1.

Rational design of a parthenolide-based drug regimen that selectively eradicates acute myelogenous leukemia stem cells.

Pei S, Minhajuddin M, D'Alessandro A, Nemkov T, Stevens BM, Adane B, Khan N, Hagen FK, Yadav VK, De S, Ashton JM, Hansen KC, Gutman JA, Pollyea DA, Crooks PA, Smith C, Jordan CT.

J Biol Chem. 2016 Nov 25;291(48):25280. No abstract available.

2.

Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells.

Pei S, Minhajuddin M, D'Alessandro A, Nemkov T, Stevens BM, Adane B, Khan N, Hagen FK, Yadav VK, De S, Ashton JM, Hansen KC, Gutman JA, Pollyea DA, Crooks PA, Smith C, Jordan CT.

J Biol Chem. 2016 Oct 14;291(42):21984-22000. Epub 2016 Aug 29. Erratum in: J Biol Chem. 2016 Nov 25;291(48):25280.

3.

Acetylation-defective mutant of Pparγ is associated with decreased lipid synthesis in breast cancer cells.

Tian L, Wang C, Hagen FK, Gormley M, Addya S, Soccio R, Casimiro MC, Zhou J, Powell MJ, Xu P, Deng H, Sauve AA, Pestell RG.

Oncotarget. 2014 Sep 15;5(17):7303-15.

4.

β-l-1-[5-(E-2-bromovinyl)-2-(hydroxymethyl)-1,3-(dioxolan-4-yl)] uracil (l-BHDU) prevents varicella-zoster virus replication in a SCID-Hu mouse model and does not interfere with 5-fluorouracil catabolism.

De C, Liu D, Zheng B, Singh US, Chavre S, White C, Arnold RD, Hagen FK, Chu CK, Moffat JF.

Antiviral Res. 2014 Oct;110:10-9. doi: 10.1016/j.antiviral.2014.07.007. Epub 2014 Jul 19.

5.

Modification of Streptococcus mutans Cnm by PgfS contributes to adhesion, endothelial cell invasion, and virulence.

Avilés-Reyes A, Miller JH, Simpson-Haidaris PJ, Hagen FK, Abranches J, Lemos JA.

J Bacteriol. 2014 Aug;196(15):2789-97. doi: 10.1128/JB.01783-14. Epub 2014 May 16.

6.

Bladder cancer exosomes contain EDIL-3/Del1 and facilitate cancer progression.

Beckham CJ, Olsen J, Yin PN, Wu CH, Ting HJ, Hagen FK, Scosyrev E, Messing EM, Lee YF.

J Urol. 2014 Aug;192(2):583-92. doi: 10.1016/j.juro.2014.02.035. Epub 2014 Feb 14.

PMID:
24530986
7.

Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells.

Pei S, Minhajuddin M, Callahan KP, Balys M, Ashton JM, Neering SJ, Lagadinou ED, Corbett C, Ye H, Liesveld JL, O'Dwyer KM, Li Z, Shi L, Greninger P, Settleman J, Benes C, Hagen FK, Munger J, Crooks PA, Becker MW, Jordan CT.

J Biol Chem. 2013 Nov 22;288(47):33542-58. doi: 10.1074/jbc.M113.511170. Epub 2013 Oct 2.

8.

The human biliverdin reductase-based peptide fragments and biliverdin regulate protein kinase Cδ activity: the peptides are inhibitors or substrate for the protein kinase C.

Miralem T, Lerner-Marmarosh N, Gibbs PE, Tudor C, Hagen FK, Maines MD.

J Biol Chem. 2012 Jul 13;287(29):24698-712. doi: 10.1074/jbc.M111.326504. Epub 2012 May 14.

9.

Proteoglycan: site mapping and site-directed mutagenesis.

Hagen FK.

Methods Mol Biol. 2012;836:23-34. doi: 10.1007/978-1-61779-498-8_2.

PMID:
22252625
10.

Identification of membrane-bound variant of metalloendopeptidase neurolysin (EC 3.4.24.16) as the non-angiotensin type 1 (non-AT1), non-AT2 angiotensin binding site.

Wangler NJ, Santos KL, Schadock I, Hagen FK, Escher E, Bader M, Speth RC, Karamyan VT.

J Biol Chem. 2012 Jan 2;287(1):114-22. doi: 10.1074/jbc.M111.273052. Epub 2011 Oct 28.

11.

Aspirin acetylates multiple cellular proteins in HCT-116 colon cancer cells: Identification of novel targets.

Marimuthu S, Chivukula RS, Alfonso LF, Moridani M, Hagen FK, Bhat GJ.

Int J Oncol. 2011 Nov;39(5):1273-83. doi: 10.3892/ijo.2011.1113. Epub 2011 Jul 4.

PMID:
21743961
12.

Use of affinity-directed liquid chromatography-mass spectrometry to map the epitopes of a factor VIII inhibitor antibody fraction.

Griffiths AE, Wang W, Hagen FK, Fay PJ.

J Thromb Haemost. 2011 Aug;9(8):1534-40. doi: 10.1111/j.1538-7836.2011.04397.x.

13.

Melampomagnolide B: a new antileukemic sesquiterpene.

Nasim S, Pei S, Hagen FK, Jordan CT, Crooks PA.

Bioorg Med Chem. 2011 Feb 15;19(4):1515-9. doi: 10.1016/j.bmc.2010.12.045. Epub 2011 Jan 6.

PMID:
21273084
14.

Human common salivary protein 1 (CSP-1) promotes binding of Streptococcus mutans to experimental salivary pellicle and glucans formed on hydroxyapatite surface.

Ambatipudi KS, Hagen FK, Delahunty CM, Han X, Shafi R, Hryhorenko J, Gregoire S, Marquis RE, Melvin JE, Koo H, Yates JR 3rd.

J Proteome Res. 2010 Dec 3;9(12):6605-14. doi: 10.1021/pr100786y. Epub 2010 Oct 22.

15.

Quantitative analysis of age specific variation in the abundance of human female parotid salivary proteins.

Ambatipudi KS, Lu B, Hagen FK, Melvin JE, Yates JR.

J Proteome Res. 2009 Nov;8(11):5093-102. doi: 10.1021/pr900478h.

16.

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).

Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR.

J Proteome Res. 2009 Mar;8(3):1304-14. doi: 10.1021/pr800658c.

17.

The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions.

Denny P, Hagen FK, Hardt M, Liao L, Yan W, Arellanno M, Bassilian S, Bedi GS, Boontheung P, Cociorva D, Delahunty CM, Denny T, Dunsmore J, Faull KF, Gilligan J, Gonzalez-Begne M, Halgand F, Hall SC, Han X, Henson B, Hewel J, Hu S, Jeffrey S, Jiang J, Loo JA, Ogorzalek Loo RR, Malamud D, Melvin JE, Miroshnychenko O, Navazesh M, Niles R, Park SK, Prakobphol A, Ramachandran P, Richert M, Robinson S, Sondej M, Souda P, Sullivan MA, Takashima J, Than S, Wang J, Whitelegge JP, Witkowska HE, Wolinsky L, Xie Y, Xu T, Yu W, Ytterberg J, Wong DT, Yates JR 3rd, Fisher SJ.

J Proteome Res. 2008 May;7(5):1994-2006. doi: 10.1021/pr700764j. Epub 2008 Mar 25.

18.

Initiation of protein O glycosylation by the polypeptide GalNAcT-1 in vascular biology and humoral immunity.

Tenno M, Ohtsubo K, Hagen FK, Ditto D, Zarbock A, Schaerli P, von Andrian UH, Ley K, Le D, Tabak LA, Marth JD.

Mol Cell Biol. 2007 Dec;27(24):8783-96. Epub 2007 Oct 8.

19.

Systematic Analysis of proteoglycan modification sites in Caenorhabditis elegans by scanning mutagenesis.

Wang H, Julenius K, Hryhorenko J, Hagen FK.

J Biol Chem. 2007 May 11;282(19):14586-97. Epub 2007 Mar 16.

20.

The terminal phase of cytokinesis in the Caenorhabditis elegans early embryo requires protein glycosylation.

Wang H, Spang A, Sullivan MA, Hryhorenko J, Hagen FK.

Mol Biol Cell. 2005 Sep;16(9):4202-13. Epub 2005 Jun 29.

21.

cDNA cloning and expression of UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase T1 from Toxoplasma gondii.

Wojczyk BS, Stwora-Wojczyk MM, Hagen FK, Striepen B, Hang HC, Bertozzi CR, Roos DS, Spitalnik SL.

Mol Biochem Parasitol. 2003 Oct;131(2):93-107.

PMID:
14511808
22.

Cloning and characterization of a ninth member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family, ppGaNTase-T9.

Ten Hagen KG, Bedi GS, Tetaert D, Kingsley PD, Hagen FK, Balys MM, Beres TM, Degand P, Tabak LA.

J Biol Chem. 2001 May 18;276(20):17395-404. Epub 2001 Feb 6.

23.

Characterization of a UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase that displays glycopeptide N-acetylgalactosaminyltransferase activity.

Ten Hagen KG, Tetaert D, Hagen FK, Richet C, Beres TM, Gagnon J, Balys MM, VanWuyckhuyse B, Bedi GS, Degand P, Tabak LA.

J Biol Chem. 1999 Sep 24;274(39):27867-74.

25.

Cloning and expression of a novel, tissue specifically expressed member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family.

Ten Hagen KG, Hagen FK, Balys MM, Beres TM, Van Wuyckhuyse B, Tabak LA.

J Biol Chem. 1998 Oct 16;273(42):27749-54.

26.
28.

Charge distribution of flanking amino acids inhibits O-glycosylation of several single-site acceptors in vivo.

Nehrke K, Ten Hagen KG, Hagen FK, Tabak LA.

Glycobiology. 1997 Dec;7(8):1053-60.

PMID:
9455905
30.

cDNA cloning and expression of a novel UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase.

Hagen FK, Ten Hagen KG, Beres TM, Balys MM, VanWuyckhuyse BC, Tabak LA.

J Biol Chem. 1997 May 23;272(21):13843-8.

31.

Cloning and expression of mouse UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-T3.

Zara J, Hagen FK, Ten Hagen KG, Van Wuyckhuyse BC, Tabak LA.

Biochem Biophys Res Commun. 1996 Nov 1;228(1):38-44.

PMID:
8912633
32.

Molecular cloning and characterization of the gene encoding rat submandibular gland apomucin, Mucsmg.

Albone EF, Hagen FK, Szpirer C, Tabak LA.

Glycoconj J. 1996 Oct;13(5):709-16.

PMID:
8909997
33.

Charge distribution of flanking amino acids influences O-glycan acquisition in vivo.

Nehrke K, Hagen FK, Tabak LA.

J Biol Chem. 1996 Mar 22;271(12):7061-5.

34.

T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombination.

Hennet T, Hagen FK, Tabak LA, Marth JD.

Proc Natl Acad Sci U S A. 1995 Dec 19;92(26):12070-4.

35.

Cloning and sequence homology of a rat UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase.

Hagen FK, Gregoire CA, Tabak LA.

Glycoconj J. 1995 Dec;12(6):901-9.

PMID:
8748168
36.
37.

Molecular cloning of a rat submandibular gland apomucin.

Albone EF, Hagen FK, VanWuyckhuyse BC, Tabak LA.

J Biol Chem. 1994 Jun 17;269(24):16845-52.

38.

Purification, cloning, and expression of a bovine UDP-GalNAc: polypeptide N-acetyl-galactosaminyltransferase.

Hagen FK, Van Wuyckhuyse B, Tabak LA.

J Biol Chem. 1993 Sep 5;268(25):18960-5.

39.

The influence of flanking sequence on the O-glycosylation of threonine in vitro.

O'Connell BC, Hagen FK, Tabak LA.

J Biol Chem. 1992 Dec 15;267(35):25010-8.

40.

Electron microscopy of SV40 DNA cross-linked by anti-Z DNA IgG.

Hagen FK, Zarling DA, Jovin TM.

EMBO J. 1985 Mar;4(3):837-44.

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