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Items: 1 to 50 of 91

1.

Colorectal premalignancy is associated with consensus molecular subtypes 1 and 2.

Chang K, Willis JA, Reumers J, Taggart MW, San Lucas FA, Thirumurthi S, Kanth P, Delker DA, Hagedorn CH, Lynch PM, Ellis LM, Hawk ET, Scheet PA, Kopetz S, Arts J, Guinney J, Dienstmann R, Vilar E.

Ann Oncol. 2018 Oct 1;29(10):2061-2067. doi: 10.1093/annonc/mdy337.

PMID:
30412224
2.

Platform-independent gene expression signature differentiates sessile serrated adenomas/polyps and hyperplastic polyps of the colon.

Rahmatallah Y, Khaidakov M, Lai KK, Goyne HE, Lamps LW, Hagedorn CH, Glazko G.

BMC Med Genomics. 2017 Dec 28;10(1):81. doi: 10.1186/s12920-017-0317-7.

3.

Activation of PERK-Nrf2 oncogenic signaling promotes Mdm2-mediated Rb degradation in persistently infected HCV culture.

Aydin Y, Chedid M, Chava S, Danielle Williams D, Liu S, Hagedorn CH, Sumitran-Holgersson S, Reiss K, Moroz K, Lu H, Balart LA, Dash S.

Sci Rep. 2017 Aug 23;7(1):9223. doi: 10.1038/s41598-017-10087-6.

4.

Gastric Proteins MUC5AC and TFF1 as Potential Diagnostic Markers of Colonic Sessile Serrated Adenomas/Polyps.

Khaidakov M, Lai KK, Roudachevski D, Sargsyan J, Goyne HE, Pai RK, Lamps LW, Hagedorn CH.

Am J Clin Pathol. 2016 Nov 1;146(5):530-537. doi: 10.1093/ajcp/aqw142.

5.

Hepatitis-C-virus-induced microRNAs dampen interferon-mediated antiviral signaling.

Jarret A, McFarland AP, Horner SM, Kell A, Schwerk J, Hong M, Badil S, Joslyn RC, Baker DP, Carrington M, Hagedorn CH, Gale M Jr, Savan R.

Nat Med. 2016 Dec;22(12):1475-1481. doi: 10.1038/nm.4211. Epub 2016 Nov 14.

6.

Interferon lambda 4 expression is suppressed by the host during viral infection.

Hong M, Schwerk J, Lim C, Kell A, Jarret A, Pangallo J, Loo YM, Liu S, Hagedorn CH, Gale M Jr, Savan R.

J Exp Med. 2016 Nov 14;213(12):2539-2552. Epub 2016 Oct 31.

7.

Gene Signature in Sessile Serrated Polyps Identifies Colon Cancer Subtype.

Kanth P, Bronner MP, Boucher KM, Burt RW, Neklason DW, Hagedorn CH, Delker DA.

Cancer Prev Res (Phila). 2016 Jun;9(6):456-65. doi: 10.1158/1940-6207.CAPR-15-0363. Epub 2016 Mar 29.

8.

Bcl2 is a critical regulator of bile acid homeostasis by dictating Shp and lncRNA H19 function.

Zhang Y, Liu C, Barbier O, Smalling R, Tsuchiya H, Lee S, Delker D, Zou A, Hagedorn CH, Wang L.

Sci Rep. 2016 Feb 3;6:20559. doi: 10.1038/srep20559.

9.

Tannic Acid Inhibits Hepatitis C Virus Entry into Huh7.5 Cells.

Liu S, Chen R, Hagedorn CH.

PLoS One. 2015 Jul 17;10(7):e0131358. doi: 10.1371/journal.pone.0131358. eCollection 2015.

10.

Interferon-α inducible protein 6 impairs EGFR activation by CD81 and inhibits hepatitis C virus infection.

Meyer K, Kwon YC, Liu S, Hagedorn CH, Ray RB, Ray R.

Sci Rep. 2015 Mar 11;5:9012. doi: 10.1038/srep09012.

11.

Impact of hepatitis C seropositivity on the risk of coronary heart disease events.

Pothineni NV, Delongchamp R, Vallurupalli S, Ding Z, Dai Y, Hagedorn CH, Mehta JL.

Am J Cardiol. 2014 Dec 15;114(12):1841-5. doi: 10.1016/j.amjcard.2014.09.020. Epub 2014 Sep 28.

12.

RNA sequencing of sessile serrated colon polyps identifies differentially expressed genes and immunohistochemical markers.

Delker DA, McGettigan BM, Kanth P, Pop S, Neklason DW, Bronner MP, Burt RW, Hagedorn CH.

PLoS One. 2014 Feb 12;9(2):e88367. doi: 10.1371/journal.pone.0088367. eCollection 2014.

13.
14.

The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus-induced microRNAs.

McFarland AP, Horner SM, Jarret A, Joslyn RC, Bindewald E, Shapiro BA, Delker DA, Hagedorn CH, Carrington M, Gale M Jr, Savan R.

Nat Immunol. 2014 Jan;15(1):72-9. doi: 10.1038/ni.2758. Epub 2013 Nov 17.

15.

HCV infection selectively impairs type I but not type III IFN signaling.

Chandra PK, Bao L, Song K, Aboulnasr FM, Baker DP, Shores N, Wimley WC, Liu S, Hagedorn CH, Fuchs SY, Wu T, Balart LA, Dash S.

Am J Pathol. 2014 Jan;184(1):214-29. doi: 10.1016/j.ajpath.2013.10.005. Epub 2013 Nov 9.

16.

Genome-wide transcriptome analysis identifies novel gene signatures implicated in human chronic liver disease.

Smalling RL, Delker DA, Zhang Y, Nieto N, McGuiness MS, Liu S, Friedman SL, Hagedorn CH, Wang L.

Am J Physiol Gastrointest Liver Physiol. 2013 Sep 1;305(5):G364-74. doi: 10.1152/ajpgi.00077.2013. Epub 2013 Jun 27.

17.

IL-1β production through the NLRP3 inflammasome by hepatic macrophages links hepatitis C virus infection with liver inflammation and disease.

Negash AA, Ramos HJ, Crochet N, Lau DT, Doehle B, Papic N, Delker DA, Jo J, Bertoletti A, Hagedorn CH, Gale M Jr.

PLoS Pathog. 2013;9(4):e1003330. doi: 10.1371/journal.ppat.1003330. Epub 2013 Apr 25.

18.

A cell culture adapted HCV JFH1 variant that increases viral titers and permits the production of high titer infectious chimeric reporter viruses.

Liu S, Xiao L, Nelson C, Hagedorn CH.

PLoS One. 2012;7(9):e44965. doi: 10.1371/journal.pone.0044965. Epub 2012 Sep 13. Erratum in: PLoS One. 2013;8(5). doi:10.1371/annotation/2e81c9a3-4700-4869-aee9-f079092c77cd. Hagedorn, Curt [corrected to Hagedorn, Curt H].

19.

Mechanism of thrombocytopenia in chronic hepatitis C as evaluated by the immature platelet fraction.

Zucker ML, Hagedorn CH, Murphy CA, Stanley S, Reid KJ, Skikne BS.

Int J Lab Hematol. 2012 Oct;34(5):525-32. doi: 10.1111/j.1751-553X.2012.01429.x. Epub 2012 Jun 18.

PMID:
22708981
20.

RNA-sequencing analysis of 5' capped RNAs identifies many new differentially expressed genes in acute hepatitis C virus infection.

Papic N, Maxwell CI, Delker DA, Liu S, Heale BS, Hagedorn CH.

Viruses. 2012 Apr;4(4):581-612. doi: 10.3390/v4040581. Epub 2012 Apr 16.

21.

The pharmacokinetics of peginterferon alfa-2a and ribavirin in African American, Hispanic and Caucasian patients with chronic hepatitis C.

Brennan BJ, Morcos PN, Wang K, Blotner SD, Morrison R, Hagedorn CH, Marbury TC, Sulkowski M, Grippo JF.

Aliment Pharmacol Ther. 2012 May;35(10):1209-20. doi: 10.1111/j.1365-2036.2012.05079.x. Epub 2012 Apr 3.

22.

Phenotypic and genotypic differences between a child with vertically acquired severe hepatitis C liver disease and his mother.

Roy A, Wang C, Li C, Lu L, Torbenson M, Hagedorn CH, Schwarz KB.

J Pediatr Gastroenterol Nutr. 2012 Apr;54(4):567-9. doi: 10.1097/MPG.0b013e318229d96f. No abstract available.

23.

ENCODE tiling array analysis identifies differentially expressed annotated and novel 5' capped RNAs in hepatitis C infected liver.

Folkers ME, Delker DA, Maxwell CI, Nelson CA, Schwartz JJ, Nix DA, Hagedorn CH.

PLoS One. 2011 Feb 16;6(2):e14697. doi: 10.1371/journal.pone.0014697.

24.

Measuring antiviral activity of benzimidazole molecules that alter IRES RNA structure with an infectious hepatitis C virus chimera expressing Renilla luciferase.

Liu S, Nelson CA, Xiao L, Lu L, Seth PP, Davis DR, Hagedorn CH.

Antiviral Res. 2011 Jan;89(1):54-63. doi: 10.1016/j.antiviral.2010.11.004. Epub 2010 Nov 12.

25.

Role of nuclear receptor SHP in metabolism and cancer.

Zhang Y, Hagedorn CH, Wang L.

Biochim Biophys Acta. 2011 Aug;1812(8):893-908. doi: 10.1016/j.bbadis.2010.10.006. Epub 2010 Oct 20. Review.

26.

Further insights into the roles of GTP and the C terminus of the hepatitis C virus polymerase in the initiation of RNA synthesis.

Harrus D, Ahmed-El-Sayed N, Simister PC, Miller S, Triconnet M, Hagedorn CH, Mahias K, Rey FA, Astier-Gin T, Bressanelli S.

J Biol Chem. 2010 Oct 22;285(43):32906-18. doi: 10.1074/jbc.M110.151316. Epub 2010 Aug 20.

27.

Genome-wide characterization of methylguanosine-capped and polyadenylated small RNAs in the rice blast fungus Magnaporthe oryzae.

Gowda M, Nunes CC, Sailsbery J, Xue M, Chen F, Nelson CA, Brown DE, Oh Y, Meng S, Mitchell T, Hagedorn CH, Dean RA.

Nucleic Acids Res. 2010 Nov;38(21):7558-69. doi: 10.1093/nar/gkq583. Epub 2010 Jul 21.

28.

Human RNA polymerase III transcriptomes and relationships to Pol II promoter chromatin and enhancer-binding factors.

Oler AJ, Alla RK, Roberts DN, Wong A, Hollenhorst PC, Chandler KJ, Cassiday PA, Nelson CA, Hagedorn CH, Graves BJ, Cairns BR.

Nat Struct Mol Biol. 2010 May;17(5):620-8. doi: 10.1038/nsmb.1801. Epub 2010 Apr 25.

29.

Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: a randomized placebo-controlled, double-blind trial.

Meyskens FL Jr, McLaren CE, Pelot D, Fujikawa-Brooks S, Carpenter PM, Hawk E, Kelloff G, Lawson MJ, Kidao J, McCracken J, Albers CG, Ahnen DJ, Turgeon DK, Goldschmid S, Lance P, Hagedorn CH, Gillen DL, Gerner EW.

Cancer Prev Res (Phila). 2008 Jun;1(1):32-8. doi: 10.1158/1940-6207.CAPR-08-0042.

30.

The unique HCV genotype distribution and the discovery of a novel subtype 6u among IDUs co-infected with HIV-1 in Yunnan, China.

Xia X, Lu L, Tee KK, Zhao W, Wu J, Yu J, Li X, Lin Y, Mukhtar MM, Hagedorn CH, Takebe Y.

J Med Virol. 2008 Jul;80(7):1142-52. doi: 10.1002/jmv.21204.

31.

Efficient 5' cap-dependent RNA purification : use in identifying and studying subsets of RNA.

Bajak EZ, Hagedorn CH.

Methods Mol Biol. 2008;419:147-60. doi: 10.1007/978-1-59745-033-1_10.

PMID:
18369981
32.

Complete genomes of three subtype 6t isolates and analysis of many novel hepatitis C virus variants within genotype 6.

Lu L, Murphy D, Li C, Liu S, Xia X, Pham PH, Jin Y, Hagedorn CH, Abe K.

J Gen Virol. 2008 Feb;89(Pt 2):444-52. doi: 10.1099/vir.0.83460-0.

PMID:
18198375
33.

Complete genomes of hepatitis C virus (HCV) subtypes 6c, 6l, 6o, 6p and 6q: completion of a full panel of genomes for HCV genotype 6.

Lu L, Li C, Fu Y, Gao F, Pybus OG, Abe K, Okamoto H, Hagedorn CH, Murphy D.

J Gen Virol. 2007 May;88(Pt 5):1519-25.

PMID:
17412981
34.

Complete genomes for hepatitis C virus subtypes 6f, 6i, 6j and 6m: viral genetic diversity among Thai blood donors and infected spouses.

Lu L, Li C, Fu Y, Thaikruea L, Thongswat S, Maneekarn N, Apichartpiyakul C, Hotta H, Okamoto H, Netski D, Pybus OG, Murphy D, Hagedorn CH, Nelson KE.

J Gen Virol. 2007 May;88(Pt 5):1505-18.

PMID:
17412980
35.

Diagnostic accuracy of EUS for vascular invasion in pancreatic and periampullary cancers: a meta-analysis and systematic review.

Puli SR, Singh S, Hagedorn CH, Reddy J, Olyaee M.

Gastrointest Endosc. 2007 May;65(6):788-97. Epub 2007 Mar 9. Review.

PMID:
17350008
36.

Eukaryotic initiation factor 4E variants alter the morphology, proliferation, and colony-formation properties of MDA-MB-435 cancer cells.

Goldson TM, Vielhauer G, Staub E, Miller S, Shim H, Hagedorn CH.

Mol Carcinog. 2007 Jan;46(1):71-84.

PMID:
17091471
37.
38.

Black patients with chronic hepatitis C have a lower sustained viral response rate than non-Blacks with genotype 1, but the same with genotypes 2/3, and this is not explained by more frequent dose reductions of interferon and ribavirin*.

Bräu N, Bini EJ, Currie S, Shen H, Schmidt WN, King PD, Ho SB, Cheung RC, Hu KQ, Anand BS, Simon FR, Aytaman A, Johnson DP, Awad JA, Ahmad J, Mendenhall CL, Pedrosa MC, Moseley RH, Hagedorn CH, Waters B, Chang KM, Morgan TR, Rossi SJ, Jeffers LJ, Wright TL; VA-HCV-001 Study Group.

J Viral Hepat. 2006 Apr;13(4):242-9.

PMID:
16611190
39.

Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection.

Loo YM, Owen DM, Li K, Erickson AK, Johnson CL, Fish PM, Carney DS, Wang T, Ishida H, Yoneyama M, Fujita T, Saito T, Lee WM, Hagedorn CH, Lau DT, Weinman SA, Lemon SM, Gale M Jr.

Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):6001-6. Epub 2006 Apr 3.

40.

Hepatitis C virus complete genome sequences identified from China representing subtypes 6k and 6n and a novel, as yet unassigned subtype within genotype 6.

Lu L, Nakano T, Li C, Fu Y, Miller S, Kuiken C, Robertson BH, Hagedorn CH.

J Gen Virol. 2006 Mar;87(Pt 3):629-34.

PMID:
16476984
41.

Phylogenetic analysis of global hepatitis E virus sequences: genetic diversity, subtypes and zoonosis.

Lu L, Li C, Hagedorn CH.

Rev Med Virol. 2006 Jan-Feb;16(1):5-36. Review.

PMID:
16175650
42.

DNA microarrays and data mining to study hepatic fibrosis.

Schnabl B, Choi YH, Hagedorn CH, Bataller R.

Methods Mol Med. 2005;117:359-69.

PMID:
16118462
43.

Laminar shear stress and 3' polyadenylation of eNOS mRNA.

Weber M, Hagedorn CH, Harrison DG, Searles CD.

Circ Res. 2005 Jun 10;96(11):1161-8. Epub 2005 May 19.

PMID:
15905462
44.

A refined long RT-PCR technique to amplify complete viral RNA genome sequences from clinical samples: application to a novel hepatitis C virus variant of genotype 6.

Lu L, Nakano T, Smallwood GA, Heffron TG, Robertson BH, Hagedorn CH.

J Virol Methods. 2005 Jun;126(1-2):139-48.

PMID:
15847930
45.

A mutant of eukaryotic protein synthesis initiation factor eIF4E(K119A) has an increased binding affinity for both m7G cap analogues and eIF4G peptides.

Friedland DE, Wooten WN, LaVoy JE, Hagedorn CH, Goss DJ.

Biochemistry. 2005 Mar 22;44(11):4546-50.

PMID:
15766285
46.
47.

Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs.

Cai X, Hagedorn CH, Cullen BR.

RNA. 2004 Dec;10(12):1957-66. Epub 2004 Nov 3.

48.
49.

NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis.

Bataller R, Schwabe RF, Choi YH, Yang L, Paik YH, Lindquist J, Qian T, Schoonhoven R, Hagedorn CH, Lemasters JJ, Brenner DA.

J Clin Invest. 2003 Nov;112(9):1383-94.

50.

Purifying mRNAs with a high-affinity eIF4E mutant identifies the short 3' poly(A) end phenotype.

Choi YH, Hagedorn CH.

Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7033-8. Epub 2003 May 30.

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