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Biomarker Correlates of Coronary Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction.

Tromp J, Hage C, Ouwerkerk W, Sanders-van Wijk S, Svedlund S, Saraste A, Ljung Faxén U, Lagerstrom Fermer M, Gan LM, Lund LH, Shah SJ, Lam CSP.

Circulation. 2019 Oct 15;140(16):1359-1361. doi: 10.1161/CIRCULATIONAHA.119.042569. Epub 2019 Oct 14. No abstract available.


Severe skin extravasation injury following intravenous injection of potassium chloride.

Richa FC, Chalhoub VR, El-Hage CF, Yazbeck PH.

Saudi J Anaesth. 2019 Oct-Dec;13(4):397-398. doi: 10.4103/sja.SJA_451_19. No abstract available.


Clinical Practice Guideline Summary for Clinicians: Microbiological Laboratory Testing in the Diagnosis of Fungal Infections in Pulmonary and Critical Care Practice.

Hage CA, Carmona EM, Evans SE, Limper AH, Ruminjo J, Thomson CC.

Ann Am Thorac Soc. 2019 Sep 17. doi: 10.1513/AnnalsATS.201908-582CME. [Epub ahead of print] No abstract available.


Microbiological Laboratory Testing in the Diagnosis of Fungal Infections in Pulmonary and Critical Care Practice. An Official American Thoracic Society Clinical Practice Guideline.

Hage CA, Carmona EM, Epelbaum O, Evans SE, Gabe LM, Haydour Q, Knox KS, Kolls JK, Murad MH, Wengenack NL, Limper AH.

Am J Respir Crit Care Med. 2019 Sep 1;200(5):535-550. doi: 10.1164/rccm.201906-1185ST.


Long term survival after lung transplantation: A single center experience.

Blitzer D, Copeland H, Roe D, Hage C, Wang IW, Duncan M, Manghelli J, Gooch D, Wozniak T.

J Card Surg. 2019 Aug 7. doi: 10.1111/jocs.14163. [Epub ahead of print]


Peak post-transplant lung function in bilateral lung transplant recipients using a prediction model based on donor and recipient demographic characteristics.

Azar M, Krishnan S, Stump TE, Gutteridge D, Roe DW, Hage C.

Respir Med. 2019 Aug;155:29-35. doi: 10.1016/j.rmed.2019.07.009. Epub 2019 Jul 5.


Characterizing responsive and refractory orthotopic mouse models of hepatocellular carcinoma in cancer immunotherapy.

Hage C, Hoves S, Ashoff M, Schandl V, Hört S, Rieder N, Heichinger C, Berrera M, Ries CH, Kiessling F, Pöschinger T.

PLoS One. 2019 Jul 10;14(7):e0219517. doi: 10.1371/journal.pone.0219517. eCollection 2019.


Serological responses of Australian horses using a commercial duplex indirect ELISA following vaccination against strangles.

El-Hage CM, Bannai H, Wiethoelter AK, Firestone SM, Heislers CM, Allen JL, Waller AS, Gilkerson JR.

Aust Vet J. 2019 Jul;97(7):220-224. doi: 10.1111/avj.12825.


Diagnosis of Fungal Infections. A Systematic Review and Meta-Analysis Supporting American Thoracic Society Practice Guideline.

Haydour Q, Hage CA, Carmona EM, Epelbaum O, Evans SE, Gabe LM, Knox KS, Kolls JK, Wengenack NL, Prokop LJ, Limper AH, Murad MH.

Ann Am Thorac Soc. 2019 Sep;16(9):1179-1188. doi: 10.1513/AnnalsATS.201811-766OC.


Prognostic impact of Framingham heart failure criteria in heart failure with preserved ejection fraction.

Löfström U, Hage C, Savarese G, Donal E, Daubert JC, Lund LH, Linde C.

ESC Heart Fail. 2019 Aug;6(4):830-839. doi: 10.1002/ehf2.12458. Epub 2019 Jun 17.


Systematic review of gastrointestinal nematodes of horses from Australia.

Saeed MA, Beveridge I, Abbas G, Beasley A, Bauquier J, Wilkes E, Jacobson C, Hughes KJ, El-Hage C, O'Handley R, Hurley J, Cudmore L, Carrigan P, Walter L, Tennent-Brown B, Nielsen MK, Jabbar A.

Parasit Vectors. 2019 Apr 29;12(1):188. doi: 10.1186/s13071-019-3445-4.


Do Patients With Acute Heart Failure and Preserved Ejection Fraction Have Heart Failure at Follow-Up: Implications of the Framingham Criteria.

Hage C, Löfström U, Donal E, Oger E, Kapłon-Cieślicka A, Daubert JC, Linde C, Lund LH.

J Card Fail. 2019 Apr 26. pii: S1071-9164(19)30019-3. doi: 10.1016/j.cardfail.2019.04.013. [Epub ahead of print]


Sorafenib Induces Pyroptosis in Macrophages and Triggers Natural Killer Cell-Mediated Cytotoxicity Against Hepatocellular Carcinoma.

Hage C, Hoves S, Strauss L, Bissinger S, Prinz Y, Pöschinger T, Kiessling F, Ries CH.

Hepatology. 2019 Oct;70(4):1280-1297. doi: 10.1002/hep.30666. Epub 2019 May 21.


Osteoporosis awareness and health beliefs among Lebanese women aged 40 years and above.

El Hage C, Hallit S, Akel M, Dagher E.

Osteoporos Int. 2019 Apr;30(4):771-786. doi: 10.1007/s00198-019-04901-2. Epub 2019 Mar 6.


Transcriptomics of cardiac biopsies reveals differences in patients with or without diagnostic parameters for heart failure with preserved ejection fraction.

Das S, Frisk C, Eriksson MJ, Walentinsson A, Corbascio M, Hage C, Kumar C, Asp M, Lundeberg J, Maret E, Persson H, Linde C, Persson B.

Sci Rep. 2019 Feb 28;9(1):3179. doi: 10.1038/s41598-019-39445-2.


ST2 in heart failure with preserved and reduced ejection fraction.

Najjar E, Faxén UL, Hage C, Donal E, Daubert JC, Linde C, Lund LH.

Scand Cardiovasc J. 2019 Feb;53(1):21-27. doi: 10.1080/14017431.2019.1583363. Epub 2019 Mar 8.


A readily usable two-photon fluorescence lifetime microendoscope.

Hage CH, Leclerc P, Fabert M, Bardet SM, Brevier J, Ducourthial G, Mansuryan T, Leray A, Kudlinski A, Louradour F.

J Biophotonics. 2019 May;12(5):e201800276. doi: 10.1002/jbio.201800276. Epub 2019 Jan 2.


Left atrial strain improves estimation of filling pressures in heart failure: a simultaneous echocardiographic and invasive haemodynamic study.

Lundberg A, Johnson J, Hage C, Bäck M, Merkely B, Venkateshvaran A, Lund LH, Nagy AI, Manouras A.

Clin Res Cardiol. 2019 Jun;108(6):703-715. doi: 10.1007/s00392-018-1399-8. Epub 2018 Dec 10.


A cross-linking/mass spectrometry workflow based on MS-cleavable cross-linkers and the MeroX software for studying protein structures and protein-protein interactions.

Iacobucci C, Götze M, Ihling CH, Piotrowski C, Arlt C, Schäfer M, Hage C, Schmidt R, Sinz A.

Nat Protoc. 2018 Dec;13(12):2864-2889. doi: 10.1038/s41596-018-0068-8.


Two-photon microscopy with a frequency-doubled fully fusion-spliced fiber laser at 1840  nm.

Hage CH, Gomes JT, Bardet SM, Granger G, Jossent M, Lavoute L, Gaponov D, Fevrier S.

Opt Lett. 2018 Oct 15;43(20):5098-5101. doi: 10.1364/OL.43.005098.


Prevalence and correlates of coronary microvascular dysfunction in heart failure with preserved ejection fraction: PROMIS-HFpEF.

Shah SJ, Lam CSP, Svedlund S, Saraste A, Hage C, Tan RS, Beussink-Nelson L, Ljung Faxén U, Fermer ML, Broberg MA, Gan LM, Lund LH.

Eur Heart J. 2018 Oct 1;39(37):3439-3450. doi: 10.1093/eurheartj/ehy531.


Importance of structural heart disease and diastolic dysfunction in heart failure with preserved ejection fraction assessed according to the ESC guidelines - A substudy in the Ka (Karolinska) Ren (Rennes) study.

Persson H, Donal E, Lund LH, Matan D, Oger E, Hage C, Daubert JC, Linde C; KaRen Investigators.

Int J Cardiol. 2019 Jan 1;274:202-207. doi: 10.1016/j.ijcard.2018.06.078. Epub 2018 Jun 20.


Detection of (1,3)-β-d-Glucan in Cerebrospinal Fluid in Histoplasma Meningitis.

Myint T, Chow FC, Bloch KC, Raymond-Guillen L, Davis TE, Wright PW, Woc-Colburn L, Khairy RN, Street AC, Yamamoto T, Albers A, Wheat LJ, Hage CA.

J Clin Microbiol. 2018 Sep 25;56(10). pii: e00663-18. doi: 10.1128/JCM.00663-18. Print 2018 Oct.


Patient reported outcome in HFpEF: Sex-specific differences in quality of life and association with outcome.

Faxén UL, Hage C, Donal E, Daubert JC, Linde C, Lund LH.

Int J Cardiol. 2018 Sep 15;267:128-132. doi: 10.1016/j.ijcard.2018.04.102.


Predictors of Long-Term Exercise Capacity in Patients Who Have Had Lung Transplantation.

Mejia-Downs A, DiPerna C, Shank C, Johnson R, Rice D, Hage C.

Prog Transplant. 2018 Sep;28(3):198-205. doi: 10.1177/1526924818781564. Epub 2018 Jun 13.


A pilot, open-label, 8-week study evaluating desvenlafaxine for treatment of major depression in methadone-maintained individuals with opioid use disorder.

El Hage C, Ghabrash MF, Dubreucq S, Brissette S, Lespérance F, Lespérance P, Ouellet-Plamondon C, Bruneau J, Jutras-Aswad D.

Int Clin Psychopharmacol. 2018 Sep;33(5):268-273. doi: 10.1097/YIC.0000000000000223.


Comparison of Prognostic Usefulness of Serum Insulin-Like Growth Factor-Binding Protein 7 in Patients With Heart Failure and Preserved Versus Reduced Left Ventricular Ejection Fraction.

Hage C, Bjerre M, Frystyk J, Gu HF, Brismar K, Donal E, Daubert JC, Linde C, Lund LH.

Am J Cardiol. 2018 Jun 15;121(12):1558-1566. doi: 10.1016/j.amjcard.2018.02.041. Epub 2018 Mar 14.


Corrigendum to "Changes in natriuretic peptides after acute hospital presentation for heart failure with preserved ejection fraction: A feasible surrogate trial endpoint? A report from the prospective Karen study" [Int. J. Cardiol. 226 (2017) 65-70].

Savarese G, Donal E, Hage C, Oger E, Persson H, Daubert JC, Linde C, Lund LH; KaRen investigators.

Int J Cardiol. 2018 Jun 15;261:240. doi: 10.1016/j.ijcard.2018.03.075. Epub 2018 Mar 27. No abstract available.


Associations With and Prognostic and Discriminatory Role of N-Terminal Pro-B-Type Natriuretic Peptide in Heart Failure With Preserved Versus Mid-range Versus Reduced Ejection Fraction.

Savarese G, Orsini N, Hage C, Dahlström U, Vedin O, Rosano GMC, Lund LH.

J Card Fail. 2018 Jun;24(6):365-374. doi: 10.1016/j.cardfail.2018.03.010. Epub 2018 Mar 27.


Central nervous system histoplasmosis: Multicenter retrospective study on clinical features, diagnostic approach and outcome of treatment.

Wheat J, Myint T, Guo Y, Kemmer P, Hage C, Terry C, Azar MM, Riddell J, Ender P, Chen S, Shehab K, Cleveland K, Esguerra E, Johnson J, Wright P, Douglas V, Vergidis P, Ooi W, Baddley J, Bamberger D, Khairy R, Vikram HR, Jenny-Avital E, Sivasubramanian G, Bowlware K, Pahud B, Sarria J, Tsai T, Assi M, Mocherla S, Prakash V, Allen D, Passaretti C, Huprikar S, Anderson A.

Medicine (Baltimore). 2018 Mar;97(13):e0245. doi: 10.1097/MD.0000000000010245. Erratum in: Medicine (Baltimore). 2018 Apr;97(16):e0537.


Haemodynamic effects of levosimendan in advanced but stable chronic heart failure.

Najjar E, Stålhberg M, Hage C, Ottenblad E, Manouras A, Haugen Löfman I, Lund LH.

ESC Heart Fail. 2018 Jun;5(3):302-308. doi: 10.1002/ehf2.12272. Epub 2018 Feb 22.


Left atrial rather than left ventricular impaired mechanics are associated with the pro-fibrotic ST2 marker and outcomes in heart failure with preserved ejection fraction.

Nagy AI, Hage C, Merkely B, Donal E, Daubert JC, Linde C, Lund LH, Manouras A.

J Intern Med. 2018 Apr;283(4):380-391. doi: 10.1111/joim.12723. Epub 2018 Feb 12.


Utilizing NT-proBNP for Eligibility and Enrichment in Trials in HFpEF, HFmrEF, and HFrEF.

Savarese G, Orsini N, Hage C, Vedin O, Cosentino F, Rosano GMC, Dahlström U, Lund LH.

JACC Heart Fail. 2018 Mar;6(3):246-256. doi: 10.1016/j.jchf.2017.12.014. Epub 2018 Feb 7.


Carboxyl-Photo-Reactive MS-Cleavable Cross-Linkers: Unveiling a Hidden Aspect of Diazirine-Based Reagents.

Iacobucci C, Götze M, Piotrowski C, Arlt C, Rehkamp A, Ihling C, Hage C, Sinz A.

Anal Chem. 2018 Feb 20;90(4):2805-2809. doi: 10.1021/acs.analchem.7b04915. Epub 2018 Feb 8.


Cell-free hemoglobin promotes primary graft dysfunction through oxidative lung endothelial injury.

Shaver CM, Wickersham N, McNeil JB, Nagata H, Miller A, Landstreet SR, Kuck JL, Diamond JM, Lederer DJ, Kawut SM, Palmer SM, Wille KM, Weinacker A, Lama VN, Crespo MM, Orens JB, Shah PD, Hage CA, Cantu E 3rd, Porteous MK, Dhillon G, McDyer J, Bastarache JA, Christie JD, Ware LB; Lung Transplant Outcomes Group (LTOG).

JCI Insight. 2018 Jan 25;3(2). pii: 98546. doi: 10.1172/jci.insight.98546. eCollection 2018 Jan 25.


Towards two-photon excited endogenous fluorescence lifetime imaging microendoscopy.

Hage CH, Leclerc P, Brevier J, Fabert M, Le Nézet C, Kudlinski A, Héliot L, Louradour F.

Biomed Opt Express. 2017 Dec 8;9(1):142-156. doi: 10.1364/BOE.9.000142. eCollection 2018 Jan 1.


Clinical and epidemiological characterization of histoplasmosis cases in a nonendemic area, Connecticut, United States.

Azar MM, Zhang X, Assi R, Hage C, Wheat LJ, Malinis MF.

Med Mycol. 2018 Oct 1;56(7):896-899. doi: 10.1093/mmy/myx120.


Improvement in Diagnosis of Histoplasma Meningitis by Combined Testing for Histoplasma Antigen and Immunoglobulin G and Immunoglobulin M Anti-Histoplasma Antibody in Cerebrospinal Fluid.

Bloch KC, Myint T, Raymond-Guillen L, Hage CA, Davis TE, Wright PW, Chow FC, Woc-Colburn L, Khairy RN, Street AC, Yamamoto T, Albers A, Wheat LJ.

Clin Infect Dis. 2018 Jan 6;66(1):89-94. doi: 10.1093/cid/cix706.


The First Zero-Length Mass Spectrometry-Cleavable Cross-Linker for Protein Structure Analysis.

Hage C, Iacobucci C, Rehkamp A, Arlt C, Sinz A.

Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14551-14555. doi: 10.1002/anie.201708273. Epub 2017 Oct 9.


Quantitative Evidence for Revising the Definition of Primary Graft Dysfunction after Lung Transplant.

Cantu E, Diamond JM, Suzuki Y, Lasky J, Schaufler C, Lim B, Shah R, Porteous M, Lederer DJ, Kawut SM, Palmer SM, Snyder LD, Hartwig MG, Lama VN, Bhorade S, Bermudez C, Crespo M, McDyer J, Wille K, Orens J, Shah PD, Weinacker A, Weill D, Wilkes D, Roe D, Hage C, Ware LB, Bellamy SL, Christie JD; Lung Transplant Outcomes Group.

Am J Respir Crit Care Med. 2018 Jan 15;197(2):235-243. doi: 10.1164/rccm.201706-1140OC.


Comparison of the Accuracy of FMT/CT and PET/MRI for the Assessment of Antibody Biodistribution in Squamous Cell Carcinoma Xenografts.

Hage C, Gremse F, Griessinger CM, Maurer A, Hoffmann SHL, Osl F, Pichler BJ, Kiessling F, Scheuer W, Pöschinger T.

J Nucl Med. 2018 Jan;59(1):44-50. doi: 10.2967/jnumed.117.197178. Epub 2017 Aug 28.


Clinical Perspectives in the Diagnosis and Management of Histoplasmosis.

Azar MM, Hage CA.

Clin Chest Med. 2017 Sep;38(3):403-415. doi: 10.1016/j.ccm.2017.04.004. Epub 2017 May 17. Review.


A Novel MS-Cleavable Azo Cross-Linker for Peptide Structure Analysis by Free Radical Initiated Peptide Sequencing (FRIPS).

Iacobucci C, Hage C, Schäfer M, Sinz A.

J Am Soc Mass Spectrom. 2017 Oct;28(10):2039-2053. doi: 10.1007/s13361-017-1744-6. Epub 2017 Jul 17.


Novel Concepts of MS-Cleavable Cross-linkers for Improved Peptide Structure Analysis.

Hage C, Falvo F, Schäfer M, Sinz A.

J Am Soc Mass Spectrom. 2017 Oct;28(10):2022-2038. doi: 10.1007/s13361-017-1712-1. Epub 2017 Jun 26.


Importance of combined left atrial size and estimated pulmonary pressure for clinical outcome in patients presenting with heart failure with preserved ejection fraction.

Donal E, Lund LH, Oger E, Bosseau C, Reynaud A, Hage C, Drouet E, Daubert JC, Linde C; KaRen Investigators.

Eur Heart J Cardiovasc Imaging. 2017 Jun 1;18(6):629-635. doi: 10.1093/ehjci/jex005.


Laboratory Diagnostics for Histoplasmosis.

Azar MM, Hage CA.

J Clin Microbiol. 2017 Jun;55(6):1612-1620. doi: 10.1128/JCM.02430-16. Epub 2017 Mar 8. Review.


Inflammatory Biomarkers Predict Heart Failure Severity and Prognosis in Patients With Heart Failure With Preserved Ejection Fraction: A Holistic Proteomic Approach.

Hage C, Michaëlsson E, Linde C, Donal E, Daubert JC, Gan LM, Lund LH.

Circ Cardiovasc Genet. 2017 Feb;10(1). pii: e001633. doi: 10.1161/CIRCGENETICS.116.001633.


Reductions in N-Terminal Pro-Brain Natriuretic Peptide Levels Are Associated With Lower Mortality and Heart Failure Hospitalization Rates in Patients With Heart Failure With Mid-Range and Preserved Ejection Fraction.

Savarese G, Hage C, Orsini N, Dahlström U, Perrone-Filardi P, Rosano GM, Lund LH.

Circ Heart Fail. 2016 Nov;9(11). pii: e003105. doi: 10.1161/CIRCHEARTFAILURE.116.003105.


The prognostic significance of atrial fibrillation in heart failure with preserved ejection function: insights from KaRen, a prospective and multicenter study.

Bosseau C, Donal E, Lund LH, Oger E, Hage C, Mulak G, Daubert JC, Linde C; KaRen investigators.

Heart Vessels. 2017 Jun;32(6):735-749. doi: 10.1007/s00380-016-0933-8. Epub 2016 Dec 27.


Rapid and strong de novo donor-specific antibody development in a lung transplant recipient: Short communication/case report.

Lobashevsky AL, Rosner KM, May JD, Duncan MD, Hage CA, Lushin EN, Anderson EE, Roe DW.

Transpl Immunol. 2017 Feb;40:17-21. doi: 10.1016/j.trim.2016.12.003. Epub 2016 Dec 12.


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