Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 64


Transferrin receptor binds virus capsid with dynamic motion.

Lee H, Callaway HM, Cifuente JO, Bator CM, Parrish CR, Hafenstein SL.

Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20462-20471. doi: 10.1073/pnas.1904918116. Epub 2019 Sep 23.


Filling AAV capsids: estimating success by cryo-EM.

Subramanian S, Maurer A, Bator C, Makhov A, Conway J, Turner KB, Marden J, Vandenberghe LH, Hafenstein S.

Hum Gene Ther. 2019 Sep 18. doi: 10.1089/hum.2019.041. [Epub ahead of print]


CryoEM reconstruction approaches to resolve asymmetric features.

Goetschius DJ, Lee H, Hafenstein S.

Adv Virus Res. 2019;105:73-91. doi: 10.1016/bs.aivir.2019.07.007.


Asymmetry in icosahedral viruses.

Goetschius DJ, Parrish CR, Hafenstein S.

Curr Opin Virol. 2019 Jun;36:67-73. doi: 10.1016/j.coviro.2019.05.006. Epub 2019 Jun 28. Review.


Parvovirus B19 Uncoating Occurs in the Cytoplasm without Capsid Disassembly and It Is Facilitated by Depletion of Capsid-Associated Divalent Cations.

Caliaro O, Marti A, Ruprecht N, Leisi R, Subramanian S, Hafenstein S, Ros C.

Viruses. 2019 May 10;11(5). pii: E430. doi: 10.3390/v11050430.


Viral engagement with host receptors blocked by a novel class of tryptophan dendrimers that targets the 5-fold-axis of the enterovirus-A71 capsid.

Sun L, Lee H, Thibaut HJ, Lanko K, Rivero-Buceta E, Bator C, Martinez-Gualda B, Dallmeier K, Delang L, Leyssen P, Gago F, San-Félix A, Hafenstein S, Mirabelli C, Neyts J.

PLoS Pathog. 2019 May 9;15(5):e1007760. doi: 10.1371/journal.ppat.1007760. eCollection 2019 May.


Examination and Reconstruction of Three Ancient Endogenous Parvovirus Capsid Protein Gene Remnants Found in Rodent Genomes.

Callaway HM, Subramanian S, Urbina CA, Barnard KN, Dick RA, Bator CM, Hafenstein SL, Gifford RJ, Parrish CR.

J Virol. 2019 Mar 5;93(6). pii: e01542-18. doi: 10.1128/JVI.01542-18. Print 2019 Mar 15.


Complex and Dynamic Interactions between Parvovirus Capsids, Transferrin Receptors, and Antibodies Control Cell Infection and Host Range.

Callaway HM, Welsch K, Weichert W, Allison AB, Hafenstein SL, Huang K, Iketani S, Parrish CR.

J Virol. 2018 Jun 13;92(13). pii: e00460-18. doi: 10.1128/JVI.00460-18. Print 2018 Jul 1.


Nuclear, Cytosolic, and Surface-Localized Poly(A)-Binding Proteins of Plasmodium yoelii.

Minns AM, Hart KJ, Subramanian S, Hafenstein S, Lindner SE.

mSphere. 2018 Jan 10;3(1). pii: e00435-17. doi: 10.1128/mSphere.00435-17. eCollection 2018 Jan-Feb.


High-Resolution Structure Analysis of Antibody V5 and U4 Conformational Epitopes on Human Papillomavirus 16.

Guan J, Bywaters SM, Brendle SA, Ashley RE, Makhov AM, Conway JF, Christensen ND, Hafenstein S.

Viruses. 2017 Dec 6;9(12). pii: E374. doi: 10.3390/v9120374.


Cryo-EM maps reveal five-fold channel structures and their modification by gatekeeper mutations in the parvovirus minute virus of mice (MVM) capsid.

Subramanian S, Organtini LJ, Grossman A, Domeier PP, Cifuente JO, Makhov AM, Conway JF, D'Abramo A Jr, Cotmore SF, Tattersall P, Hafenstein S.

Virology. 2017 Oct;510:216-223. doi: 10.1016/j.virol.2017.07.015. Epub 2017 Jul 24.


Cryoelectron Microscopy Maps of Human Papillomavirus 16 Reveal L2 Densities and Heparin Binding Site.

Guan J, Bywaters SM, Brendle SA, Ashley RE, Makhov AM, Conway JF, Christensen ND, Hafenstein S.

Structure. 2017 Feb 7;25(2):253-263. doi: 10.1016/j.str.2016.12.001. Epub 2017 Jan 5.


Using a Novel Partitivirus in Pseudogymnoascus destructans to Understand the Epidemiology of White-Nose Syndrome.

Thapa V, Turner GG, Hafenstein S, Overton BE, Vanderwolf KJ, Roossinck MJ.

PLoS Pathog. 2016 Dec 27;12(12):e1006076. doi: 10.1371/journal.ppat.1006076. eCollection 2016 Dec.


MOPS and coxsackievirus B3 stability.

Carson SD, Hafenstein S, Lee H.

Virology. 2017 Jan 15;501:183-187. doi: 10.1016/j.virol.2016.12.002. Epub 2016 Dec 8.


Honey Bee Deformed Wing Virus Structures Reveal that Conformational Changes Accompany Genome Release.

Organtini LJ, Shingler KL, Ashley RE, Capaldi EA, Durrani K, Dryden KA, Makhov AM, Conway JF, Pizzorno MC, Hafenstein S.

J Virol. 2017 Jan 3;91(2). pii: e01795-16. doi: 10.1128/JVI.01795-16. Print 2017 Jan 15.


Parvovirus Capsid Structures Required for Infection: Mutations Controlling Receptor Recognition and Protease Cleavages.

Callaway HM, Feng KH, Lee DW, Allison AB, Pinard M, McKenna R, Agbandje-McKenna M, Hafenstein S, Parrish CR.

J Virol. 2017 Jan 3;91(2). pii: e01871-16. doi: 10.1128/JVI.01871-16. Print 2017 Jan 15.


Evolution and Cryo-electron Microscopy Capsid Structure of a North American Bat Adenovirus and Its Relationship to Other Mastadenoviruses.

Hackenbrack N, Rogers MB, Ashley RE, Keel MK, Kubiski SV, Bryan JA, Ghedin E, Holmes EC, Hafenstein SL, Allison AB.

J Virol. 2017 Jan 3;91(2). pii: e01504-16. doi: 10.1128/JVI.01504-16. Print 2017 Jan 15.


Structural biology: A picornavirus unlike the others.

Hafenstein S.

Nat Microbiol. 2016 Oct 26;1(11):16217. doi: 10.1038/nmicrobiol.2016.217. No abstract available.


The novel asymmetric entry intermediate of a picornavirus captured with nanodiscs.

Lee H, Shingler KL, Organtini LJ, Ashley RE, Makhov AM, Conway JF, Hafenstein S.

Sci Adv. 2016 Aug 24;2(8):e1501929. doi: 10.1126/sciadv.1501929. eCollection 2016 Aug.


Near-Atomic Resolution Structure of a Highly Neutralizing Fab Bound to Canine Parvovirus.

Organtini LJ, Lee H, Iketani S, Huang K, Ashley RE, Makhov AM, Conway JF, Parrish CR, Hafenstein S.

J Virol. 2016 Oct 14;90(21):9733-9742. doi: 10.1128/JVI.01112-16. Print 2016 Nov 1.


Induction and Purification of C. difficile Phage Tail-Like Particles.

Hegarty JP, Sangster W, Ashley RE, Myers R, Hafenstein S, Stewart DB Sr.

Methods Mol Biol. 2016;1476:167-75. doi: 10.1007/978-1-4939-6361-4_12.


MRI contrast agent for targeting glioma: interleukin-13 labeled liposome encapsulating gadolinium-DTPA.

Liu X, Madhankumar AB, Miller PA, Duck KA, Hafenstein S, Rizk E, Slagle-Webb B, Sheehan JM, Connor JR, Yang QX.

Neuro Oncol. 2016 May;18(5):691-9. doi: 10.1093/neuonc/nov263. Epub 2015 Oct 31.


Single Mutations in the VP2 300 Loop Region of the Three-Fold Spike of the Carnivore Parvovirus Capsid Can Determine Host Range.

Allison AB, Organtini LJ, Zhang S, Hafenstein SL, Holmes EC, Parrish CR.

J Virol. 2015 Oct 28;90(2):753-67. doi: 10.1128/JVI.02636-15. Print 2016 Jan 15.


The Suramin Derivative NF449 Interacts with the 5-fold Vertex of the Enterovirus A71 Capsid to Prevent Virus Attachment to PSGL-1 and Heparan Sulfate.

Nishimura Y, McLaughlin NP, Pan J, Goldstein S, Hafenstein S, Shimizu H, Winkler JD, Bergelson JM.

PLoS Pathog. 2015 Oct 2;11(10):e1005184. doi: 10.1371/journal.ppat.1005184. eCollection 2015 Oct.


The U4 Antibody Epitope on Human Papillomavirus 16 Identified by Cryo-electron Microscopy.

Guan J, Bywaters SM, Brendle SA, Lee H, Ashley RE, Christensen ND, Hafenstein S.

J Virol. 2015 Dec;89(23):12108-17. doi: 10.1128/JVI.02020-15. Epub 2015 Sep 23.


Structural comparison of four different antibodies interacting with human papillomavirus 16 and mechanisms of neutralization.

Guan J, Bywaters SM, Brendle SA, Lee H, Ashley RE, Makhov AM, Conway JF, Christensen ND, Hafenstein S.

Virology. 2015 Sep;483:253-63. doi: 10.1016/j.virol.2015.04.016. Epub 2015 May 19.


Group Selection and Contribution of Minority Variants during Virus Adaptation Determines Virus Fitness and Phenotype.

Bordería AV, Isakov O, Moratorio G, Henningsson R, Agüera-González S, Organtini L, Gnädig NF, Blanc H, Alcover A, Hafenstein S, Fontes M, Shomron N, Vignuzzi M.

PLoS Pathog. 2015 May 5;11(5):e1004838. doi: 10.1371/journal.ppat.1004838. eCollection 2015 May.


The enterovirus 71 procapsid binds neutralizing antibodies and rescues virus infection in vitro.

Shingler KL, Cifuente JO, Ashley RE, Makhov AM, Conway JF, Hafenstein S.

J Virol. 2015 Feb;89(3):1900-8. doi: 10.1128/JVI.03098-14. Epub 2014 Nov 26.


Global displacement of canine parvovirus by a host-adapted variant: structural comparison between pandemic viruses with distinct host ranges.

Organtini LJ, Allison AB, Lukk T, Parrish CR, Hafenstein S.

J Virol. 2015 Feb;89(3):1909-12. doi: 10.1128/JVI.02611-14. Epub 2014 Nov 19.


A cryo-electron microscopy study identifies the complete H16.V5 epitope and reveals global conformational changes initiated by binding of the neutralizing antibody fragment.

Lee H, Brendle SA, Bywaters SM, Guan J, Ashley RE, Yoder JD, Makhov AM, Conway JF, Christensen ND, Hafenstein S.

J Virol. 2015 Jan 15;89(2):1428-38. doi: 10.1128/JVI.02898-14. Epub 2014 Nov 12.


Specificity of coxsackievirus B3 interaction with human, but not murine, decay-accelerating factor: replacement of a single residue within short consensus repeat 2 prevents virus attachment.

Pan J, Zhang L, Organtini LJ, Hafenstein S, Bergelson JM.

J Virol. 2015 Jan 15;89(2):1324-8. doi: 10.1128/JVI.02798-14. Epub 2014 Nov 12.


Enterovirus 71 Virus Propagation and Purification.

Shingler KL, Organtini LJ, Hafenstein S.

Bio Protoc. 2014 May 5;4(9). pii: e1117.


Kinetic and structural analysis of coxsackievirus B3 receptor interactions and formation of the A-particle.

Organtini LJ, Makhov AM, Conway JF, Hafenstein S, Carson SD.

J Virol. 2014 May;88(10):5755-65. doi: 10.1128/JVI.00299-14. Epub 2014 Mar 12.


A strain-specific epitope of enterovirus 71 identified by cryo-electron microscopy of the complex with fab from neutralizing antibody.

Lee H, Cifuente JO, Ashley RE, Conway JF, Makhov AM, Tano Y, Shimizu H, Nishimura Y, Hafenstein S.

J Virol. 2013 Nov;87(21):11363-70. doi: 10.1128/JVI.01926-13. Epub 2013 Aug 14.


Enterovirus 71 binding to PSGL-1 on leukocytes: VP1-145 acts as a molecular switch to control receptor interaction.

Nishimura Y, Lee H, Hafenstein S, Kataoka C, Wakita T, Bergelson JM, Shimizu H.

PLoS Pathog. 2013;9(7):e1003511. doi: 10.1371/journal.ppat.1003511. Epub 2013 Jul 25.


Assembly and characterization of foot-and-mouth disease virus empty capsid particles expressed within mammalian cells.

Gullberg M, Muszynski B, Organtini LJ, Ashley RE, Hafenstein SL, Belsham GJ, Polacek C.

J Gen Virol. 2013 Aug;94(Pt 8):1769-79. doi: 10.1099/vir.0.054122-0. Epub 2013 Jun 5.


Structures of the procapsid and mature virion of enterovirus 71 strain 1095.

Cifuente JO, Lee H, Yoder JD, Shingler KL, Carnegie MS, Yoder JL, Ashley RE, Makhov AM, Conway JF, Hafenstein S.

J Virol. 2013 Jul;87(13):7637-45. doi: 10.1128/JVI.03519-12. Epub 2013 May 1.


The enterovirus 71 A-particle forms a gateway to allow genome release: a cryoEM study of picornavirus uncoating.

Shingler KL, Yoder JL, Carnegie MS, Ashley RE, Makhov AM, Conway JF, Hafenstein S.

PLoS Pathog. 2013 Mar;9(3):e1003240. doi: 10.1371/journal.ppat.1003240. Epub 2013 Mar 21. Erratum in: PLoS Pathog. 2013 Sep;9(9). doi: 10.1371/annotation/e92d19e0-996a-4bfa-afdd-20dce770ed75.


The role of evolutionary intermediates in the host adaptation of canine parvovirus.

Stucker KM, Pagan I, Cifuente JO, Kaelber JT, Lillie TD, Hafenstein S, Holmes EC, Parrish CR.

J Virol. 2012 Feb;86(3):1514-21. doi: 10.1128/JVI.06222-11. Epub 2011 Nov 23.


Secretion of genome-free hepatitis B virus--single strand blocking model for virion morphogenesis of para-retrovirus.

Ning X, Nguyen D, Mentzer L, Adams C, Lee H, Ashley R, Hafenstein S, Hu J.

PLoS Pathog. 2011 Sep;7(9):e1002255. doi: 10.1371/journal.ppat.1002255. Epub 2011 Sep 22.


In VITRO ASSEMBLY of the øX174 procapsid from external scaffolding protein oligomers and early pentameric assembly intermediates.

Cherwa JE Jr, Organtini LJ, Ashley RE, Hafenstein SL, Fane BA.

J Mol Biol. 2011 Sep 23;412(3):387-96. doi: 10.1016/j.jmb.2011.07.070. Epub 2011 Aug 5.


Molecular determinants of disease in coxsackievirus B1 murine infection.

Cifuente JO, Ferrer MF, Jaquenod de Giusti C, Song WC, Romanowski V, Hafenstein SL, Gómez RM.

J Med Virol. 2011 Sep;83(9):1571-81. doi: 10.1002/jmv.22133.


Single amino acid changes in the virus capsid permit coxsackievirus B3 to bind decay-accelerating factor.

Pan J, Narayanan B, Shah S, Yoder JD, Cifuente JO, Hafenstein S, Bergelson JM.

J Virol. 2011 Jul;85(14):7436-43. doi: 10.1128/JVI.00503-11. Epub 2011 May 11.


Structure of a packaging-defective mutant of minute virus of mice indicates that the genome is packaged via a pore at a 5-fold axis.

Plevka P, Hafenstein S, Li L, D'Abrgamo A Jr, Cotmore SF, Rossmann MG, Tattersall P.

J Virol. 2011 May;85(10):4822-7. doi: 10.1128/JVI.02598-10. Epub 2011 Mar 2.


Variations of coxsackievirus B3 capsid primary structure, ligands, and stability are selected for in a coxsackievirus and adenovirus receptor-limited environment.

Carson SD, Chapman NM, Hafenstein S, Tracy S.

J Virol. 2011 Apr;85(7):3306-14. doi: 10.1128/JVI.01827-10. Epub 2011 Jan 26.


Interaction of decay-accelerating factor with echovirus 7.

Plevka P, Hafenstein S, Harris KG, Cifuente JO, Zhang Y, Bowman VD, Chipman PR, Bator CM, Lin F, Medof ME, Rossmann MG.

J Virol. 2010 Dec;84(24):12665-74. doi: 10.1128/JVI.00837-10. Epub 2010 Sep 29.


Characterization of a putative ancestor of coxsackievirus B5.

Gullberg M, Tolf C, Jonsson N, Mulders MN, Savolainen-Kopra C, Hovi T, Van Ranst M, Lemey P, Hafenstein S, Lindberg AM.

J Virol. 2010 Oct;84(19):9695-708. doi: 10.1128/JVI.00071-10. Epub 2010 Jul 14.


A single coxsackievirus B2 capsid residue controls cytolysis and apoptosis in rhabdomyosarcoma cells.

Gullberg M, Tolf C, Jonsson N, Polacek C, Precechtelova J, Badurova M, Sojka M, Mohlin C, Israelsson S, Johansson K, Bopegamage S, Hafenstein S, Lindberg AM.

J Virol. 2010 Jun;84(12):5868-79. doi: 10.1128/JVI.02383-09. Epub 2010 Apr 7. Erratum in: J Virol. 2010 Aug;84(15):7922.


Binding site on the transferrin receptor for the parvovirus capsid and effects of altered affinity on cell uptake and infection.

Goodman LB, Lyi SM, Johnson NC, Cifuente JO, Hafenstein SL, Parrish CR.

J Virol. 2010 May;84(10):4969-78. doi: 10.1128/JVI.02623-09. Epub 2010 Mar 3.

Supplemental Content

Loading ...
Support Center