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Items: 39

1.

Serotonin receptors of 5-HT2 type in the hypothalamic arcuate nuclei (ARC) positively regulate liver cytochrome P450 via stimulation of the growth hormone-releasing hormone - growth hormone (GHRH-GH) hormonal pathway.

Bromek E, Rysz M, Haduch A, Daniel WA.

Drug Metab Dispos. 2018 Dec 5. pii: dmd.118.083808. doi: 10.1124/dmd.118.083808. [Epub ahead of print]

PMID:
30518657
2.

The engagement of brain cytochrome P450 in the metabolism of endogenous neuroactive substrates: a possible role in mental disorders.

Haduch A, Daniel WA.

Drug Metab Rev. 2018 Dec 2:1-41. doi: 10.1080/03602532.2018.1554674. [Epub ahead of print]

PMID:
30501426
3.

The activity of brain and liver cytochrome P450 2D (CYP2D) is differently affected by antidepressants in the chronic mild stress (CMS) model of depression in the rat.

Haduch A, Rysz M, Papp M, Daniel WA.

Biochem Pharmacol. 2018 Oct;156:398-405. doi: 10.1016/j.bcp.2018.09.005. Epub 2018 Sep 7.

PMID:
30195732
4.

Activation of 5-HT1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat Liver.

Bromek E, Rysz M, Haduch A, Wójcikowski J, Daniel WA.

Drug Metab Dispos. 2018 Jun;46(6):786-793. doi: 10.1124/dmd.117.079632. Epub 2018 Mar 19.

PMID:
29555828
5.

The Effect of Chronic Treatment with Lurasidone on Rat Liver Cytochrome P450 Expression and Activity in the Chronic Mild Stress Model of Depression.

Kot M, Haduch A, Papp M, Daniel WA.

Drug Metab Dispos. 2017 Dec;45(12):1336-1344. doi: 10.1124/dmd.117.077826. Epub 2017 Sep 21.

6.

The reverse role of the hypothalamic paraventricular (PVN) and arcuate (ARC) nuclei in the central serotonergic regulation of the liver cytochrome P450 isoform CYP2C11.

Rysz M, Bromek E, Haduch A, Liskova B, Wójcikowski J, Daniel WA.

Biochem Pharmacol. 2016 Jul 15;112:82-9. doi: 10.1016/j.bcp.2016.04.017. Epub 2016 Apr 29.

PMID:
27137992
7.

Melatonin Supports CYP2D-Mediated Serotonin Synthesis in the Brain.

Haduch A, Bromek E, Wójcikowski J, Gołembiowska K, Daniel WA.

Drug Metab Dispos. 2016 Mar;44(3):445-52. doi: 10.1124/dmd.115.067413.

8.

Cocaine self-administration in Wistar-Kyoto rats: a behavioral and biochemical analysis.

Jastrzębska J, Frankowska M, Szumiec Ł, Sadakierska-Chudy A, Haduch A, Smaga I, Bystrowska B, Daniel WA, Filip M.

Behav Brain Res. 2015 Oct 15;293:62-73. doi: 10.1016/j.bbr.2015.06.040. Epub 2015 Jul 17.

PMID:
26192911
9.

Damage to the Brain Serotonergic System Increases the Expression of Liver Cytochrome P450.

Rysz M, Bromek E, Haduch A, Sadakierska-Chudy A, Daniel WA.

Drug Metab Dispos. 2015 Sep;43(9):1345-52. doi: 10.1124/dmd.115.064980. Epub 2015 Jun 9.

10.

The role of the dorsal noradrenergic pathway of the brain (locus coeruleus) in the regulation of liver cytochrome P450 activity.

Kot M, Sadakierska-Chudy A, Haduch A, Rysz M, Bromek E, Gołembiowska K, Daniel WA.

Eur J Pharmacol. 2015 Mar 15;751:34-41. doi: 10.1016/j.ejphar.2015.01.014. Epub 2015 Jan 28.

PMID:
25637782
11.

The cytochrome P450 2D-mediated formation of serotonin from 5-methoxytryptamine in the brain in vivo: a microdialysis study.

Haduch A, Bromek E, Kot M, Kamińska K, Gołembiowska K, Daniel WA.

J Neurochem. 2015 Apr;133(1):83-92. doi: 10.1111/jnc.13031. Epub 2015 Feb 8.

12.

Effect of antidepressant drugs on cytochrome P450 2C11 (CYP2C11) in rat liver.

Wójcikowski J, Haduch A, Daniel WA.

Pharmacol Rep. 2013;65(5):1247-55.

13.

The role of brain noradrenergic system in the regulation of liver cytochrome P450 expression.

Sadakierska-Chudy A, Haduch A, Rysz M, Gołembiowska K, Daniel WA.

Biochem Pharmacol. 2013 Sep 15;86(6):800-7. doi: 10.1016/j.bcp.2013.07.017. Epub 2013 Aug 4.

PMID:
23924605
14.

Effect of classic and atypical neuroleptics on cytochrome P450 3A (CYP3A) in rat liver.

Wójcikowski J, Haduch A, Daniel WA.

Pharmacol Rep. 2012;64(6):1411-8.

15.

The catalytic competence of cytochrome P450 in the synthesis of serotonin from 5-methoxytryptamine in the brain: an in vitro study.

Haduch A, Bromek E, Sadakierska-Chudy A, Wójcikowski J, Daniel WA.

Pharmacol Res. 2013 Jan;67(1):53-9. doi: 10.1016/j.phrs.2012.10.009. Epub 2012 Oct 23.

PMID:
23098818
16.

Effect of neuroleptics on cytochrome P450 2C11 (CYP2C11) in rat liver.

Haduch A, Wójcikowski J, Daniel WA.

Pharmacol Rep. 2011;63(6):1491-9.

17.

Cytochrome P450 mediates dopamine formation in the brain in vivo.

Bromek E, Haduch A, Gołembiowska K, Daniel WA.

J Neurochem. 2011 Sep;118(5):806-15. doi: 10.1111/j.1471-4159.2011.07339.x. Epub 2011 Jul 14.

18.

Effects of low doses of intracerebroventricular 6-OHDA on the levels of monoaminergic neurotransmitters in rat brain structures.

Sadakierska-Chudy A, Haduch A, Gołembiowska K, Daniel WA.

Pharmacol Rep. 2010 Nov-Dec;62(6):1225-30.

19.

The effect of psychotropic drugs on cytochrome P450 2D (CYP2D) in rat brain.

Haduch A, Bromek E, Daniel WA.

Eur J Pharmacol. 2011 Jan 25;651(1-3):51-8. doi: 10.1016/j.ejphar.2010.10.077. Epub 2010 Nov 27.

PMID:
21115002
20.

The ability of cytochrome P450 2D isoforms to synthesize dopamine in the brain: An in vitro study.

Bromek E, Haduch A, Daniel WA.

Eur J Pharmacol. 2010 Jan 25;626(2-3):171-8. doi: 10.1016/j.ejphar.2009.09.062. Epub 2009 Oct 8.

PMID:
19818757
21.
22.

The activity of cytochrome P450 CYP2B in rat liver during neuroleptic treatment.

Haduch A, Wójcikowski J, Daniel WA.

Pharmacol Rep. 2007 Sep-Oct;59(5):606-12.

23.

Effect of mirtazapine on the CYP2D activity in the primary culture of rat hepatocytes.

Haduch A, Bromek E, Kot M, Jemnitz K, Veres Z, Vereczkey L, Daniel WA.

Pharmacol Rep. 2006 Nov-Dec;58(6):979-84.

24.

Direct and indirect interactions between antidepressant drugs and CYP2C6 in the rat liver during long-term treatment.

Daniel WA, Haduch A, Syrek M, Boksa J.

Eur Neuropsychopharmacol. 2006 Dec;16(8):580-7. Epub 2006 Feb 28.

PMID:
16503401
25.

Interactions between neuroleptics and CYP2C6 in rat liver--in vitro and ex vivo study.

Haduch A, Ogórka T, Boksa J, Daniel WA.

Pharmacol Rep. 2005 Nov-Dec;57(6):872-7.

26.

Direct effects of neuroleptics on the activity of CYP2A in the liver of rats.

Haduch A, Wójcikowski J, Daniel WA.

Pharmacol Rep. 2005 Nov-Dec;57(6):867-71.

27.

Effect of short- and long-term treatment with antidepressant drugs on the activity of rat CYP2A in the liver.

Haduch A, Wójcikowski J, Daniel WA.

Pharmacol Rep. 2005 Nov-Dec;57(6):774-81.

28.

The effect of tricyclic antidepressants, selective serotonin reuptake inhibitors (SSRIs) and newer antidepressant drugs on the activity and level of rat CYP3A.

Haduch A, Wójcikowski J, Daniel WA.

Eur Neuropsychopharmacol. 2006 Apr;16(3):178-86. Epub 2005 Oct 24.

PMID:
16246530
29.
30.
31.

Disposition of 1,2,3,4,-tetrahydroisoquinoline in the brain of male Wistar and Dark Agouti rats.

Lorenc-Koci E, Wójcikowski J, Kot M, Haduch A, Boksa J, Daniel WA.

Brain Res. 2004 Jan 23;996(2):168-79.

PMID:
14697494
32.

Inhibition and possible induction of rat CYP2D after short- and long-term treatment with antidepressants.

Daniel WA, Haduch A, Wójcikowski J.

J Pharm Pharmacol. 2002 Nov;54(11):1545-52.

PMID:
12495558
33.

The contribution of cytochrome P-450 isoenzymes to the metabolism of phenothiazine neuroleptics.

Daniel WA, Syrek M, Haduch A.

Eur Neuropsychopharmacol. 2002 Oct;12(5):371-7.

PMID:
12208554
34.

The effect of selective serotonin reuptake inhibitors (SSRIs) on the pharmacokinetics and metabolism of perazine in the rat.

Daniel WA, Syrek M, Haduch A, Wójcikowski J.

J Pharm Pharmacol. 2001 Apr;53(4):449-61.

PMID:
11341361
35.

Different effects of amitriptyline and imipramine on the pharmacokinetics and metabolism of perazine in rats.

Daniel WA, Syrek M, Haduch A, Wójcikowski J.

J Pharm Pharmacol. 2000 Dec;52(12):1473-81.

PMID:
11197075
36.

Pharmacokinetics and metabolism of thioridazine during co-administration of tricyclic antidepressants.

Daniel WA, Syrek M, Haduch A, Wójcikowski J.

Br J Pharmacol. 2000 Sep;131(2):287-95.

37.

Effects of selective cytochrome P-450 inhibitors on the metabolism of thioridazine. In vitro studies.

Daniel WA, Syrek M, Haduch A.

Pol J Pharmacol. 1999 Sep-Oct;51(5):435-42.

PMID:
10817545
38.
39.

Pharmacokinetics of phenothiazine neuroleptics after chronic coadministration of carbamazepine.

Daniel WA, Syrek M, Haduch A, Wójcikowski J.

Pol J Pharmacol. 1998 Nov-Dec;50(6):431-42.

PMID:
10385926

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