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Mode shift of the voltage sensors in Shaker K+ channels is caused by energetic coupling to the pore domain.

Haddad GA, Blunck R.

J Gen Physiol. 2011 May;137(5):455-72. doi: 10.1085/jgp.201010573.


An intersubunit interaction between S4-S5 linker and S6 is responsible for the slow off-gating component in Shaker K+ channels.

Batulan Z, Haddad GA, Blunck R.

J Biol Chem. 2010 Apr 30;285(18):14005-19. doi: 10.1074/jbc.M109.097717. Epub 2010 Mar 4.

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