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Intermittent Hypoxia and Hypercapnia Induces Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta-dependent Atherosclerosis in Pulmonary Arteries.

Imamura T, Xue J, Poulsen O, Zhou D, Karin M, Haddad GG.

Am J Physiol Regul Integr Comp Physiol. 2019 Oct 16. doi: 10.1152/ajpregu.00056.2019. [Epub ahead of print]


Increased hypoxic proliferative response and gene expression in erythroid progenitor cells of Andean highlanders with Chronic Mountain Sickness.

Bermudez D, Azad P, Figueroa-Mujíca R, Vizcardo-Galindo G, Corante N, Guerra-Giraldez C, Haddad GG, Villafuerte FC.

Am J Physiol Regul Integr Comp Physiol. 2019 Oct 16. doi: 10.1152/ajpregu.00250.2019. [Epub ahead of print]


[An independent observatory in Vendée on ST-elevated acute myocardial infarction (the OVISCA Register). A Departmental evaluation of demographic trends, mortality and delays before treatment].

Boiffard E, Dimet J, Baron O, Billon O, Boivineau C, Charvet M, Doizon T, Federspiel C, Flori M, Georges JL, Haddad G, Lipp D, Nguyen JO, Mouhoub D, Pernollet P, Philippot M, Pouliquen H, Roy N, Trebouet E, Turlotte G, Zeninari B, Orion L.

Ann Cardiol Angeiol (Paris). 2019 Sep 18. pii: S0003-3928(19)30068-X. doi: 10.1016/j.ancard.2019.08.008. [Epub ahead of print] French.


Quality Risk Management - A Role-Based Competency Model.

Haddad G, Greene A.

PDA J Pharm Sci Technol. 2019 Sep 13. pii: pdajpst.2019.010496. doi: 10.5731/pdajpst.2019.010496. [Epub ahead of print]


Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development.

Trujillo CA, Gao R, Negraes PD, Gu J, Buchanan J, Preissl S, Wang A, Wu W, Haddad GG, Chaim IA, Domissy A, Vandenberghe M, Devor A, Yeo GW, Voytek B, Muotri AR.

Cell Stem Cell. 2019 Oct 3;25(4):558-569.e7. doi: 10.1016/j.stem.2019.08.002. Epub 2019 Aug 29.


Evolving Role of PET in Interventional Radiology-Based Oncology Procedures.

Lam MGEH, Hunt SJ, El-Haddad GE, Alavi A.

PET Clin. 2019 Oct;14(4):xiii-xiv. doi: 10.1016/j.cpet.2019.07.001. No abstract available.


Circular RNAs in Urine of Kidney Transplant Patients with Acute T Cell-Mediated Allograft Rejection.

Kölling M, Haddad G, Wegmann U, Kistler A, Bosakova A, Seeger H, Hübel K, Haller H, Mueller T, Wüthrich RP, Lorenzen JM.

Clin Chem. 2019 Oct;65(10):1287-1294. doi: 10.1373/clinchem.2019.305854. Epub 2019 Aug 1.


Interaction between anxiety and depression on suicidal ideation, quality of life, and work productivity impairment: Results from a representative sample of the Lebanese population.

Khansa W, Haddad C, Hallit R, Akel M, Obeid S, Haddad G, Soufia M, Kheir N, Abi Elias Hallit C, Khoury R, Salameh P, Hallit S.

Perspect Psychiatr Care. 2019 Jul 19. doi: 10.1111/ppc.12423. [Epub ahead of print]


Commentary: Novel Insight into the Genetic Basis of High Altitude Pulmonary Hypertension in Kyrgyz Highlanders.

Stobdan T, Haddad GG.

J Lung Health Dis. 2019;3(2):29-30. Epub 2019 Mar 19. No abstract available.


Post-anastomotic venous stenosis after Optiflow deployment: An unexpected outcome.

Al Adas Z, Haddad G, Patel BC, Kumbar L, Al-Abid B, Balraj P, Kabbani LS.

SAGE Open Med Case Rep. 2019 May 30;7:2050313X19851002. doi: 10.1177/2050313X19851002. eCollection 2019.


Quality Risk Management Competency Model-Case for the Need for QRM Competencies.

Haddad G, Greene A.

PDA J Pharm Sci Technol. 2019 Jul-Aug;73(4):331-344. doi: 10.5731/pdajpst.2019.009944. Epub 2019 May 17.


Biogenesis and Function of Circular RNAs in Health and in Disease.

Haddad G, Lorenzen JM.

Front Pharmacol. 2019 Apr 26;10:428. doi: 10.3389/fphar.2019.00428. eCollection 2019. Review.


CXCR4 Cardiac Specific Knockout Mice Develop a Progressive Cardiomyopathy.

LaRocca TJ, Altman P, Jarrah AA, Gordon R, Wang E, Hadri L, Burke MW, Haddad GE, Hajjar RJ, Tarzami ST.

Int J Mol Sci. 2019 May 8;20(9). pii: E2267. doi: 10.3390/ijms20092267.


Intermittent Hypoxia and Hypercapnia Reproducibly Change the Gut Microbiome and Metabolome across Rodent Model Systems.

Tripathi A, Xu ZZ, Xue J, Poulsen O, Gonzalez A, Humphrey G, Meehan MJ, Melnik AV, Ackermann G, Zhou D, Malhotra A, Haddad GG, Dorrestein PC, Knight R.

mSystems. 2019 Apr 30;4(2). pii: e00058-19. doi: 10.1128/mSystems.00058-19. eCollection 2019 Mar-Apr.


Frontal-subcortical behaviors during Alzheimer's disease in individuals with Down syndrome.

Fonseca LM, Mattar GP, Haddad GG, Gonçalves AS, Miguel AQC, Guilhoto LM, Zaman S, Holland AJ, Bottino CMC, Hoexter MQ.

Neurobiol Aging. 2019 Jun;78:186-194. doi: 10.1016/j.neurobiolaging.2019.02.028. Epub 2019 Mar 11.


Prevalence of Obsessive-Compulsive Disorder in Patients With Schizophrenia and Outcome on Positive and Negative Symptoms, Cognition, and Quality of Life.

Wehbé J, Haddad C, Obeid S, Hallit S, Haddad G.

J Nerv Ment Dis. 2019 Apr;207(4):239-245. doi: 10.1097/NMD.0000000000000956.


High fat diet induces sex-specific differential gene expression in Drosophila melanogaster.

Stobdan T, Sahoo D, Azad P, Hartley I, Heinrichsen E, Zhou D, Haddad GG.

PLoS One. 2019 Mar 12;14(3):e0213474. doi: 10.1371/journal.pone.0213474. eCollection 2019.


Effects of PSE meat and salt concentration on the technological and sensory characteristics of restructured cooked hams.

Paula MMO, Haddad GBS, Rodrigues LM, Benevenuto Júnior AA, Ramos ALS, Ramos EM.

Meat Sci. 2019 Jun;152:96-103. doi: 10.1016/j.meatsci.2019.02.020. Epub 2019 Feb 26.


Prenatal diagnosis of fragile X syndrome: Small meiotic recombination events at the FMR1 locus.

Bacrot S, Monnot S, Haddad G, Barcia G, Rachid M, Boisson M, Pasquier N, Rondeau S, Munnich A, Steffann J, Bonnefont JP, Raynaud M.

Prenat Diagn. 2019 Apr;39(5):388-393. doi: 10.1002/pd.5439. Epub 2019 Apr 1.


Melanocortin 1 Receptor-Targeted α-Particle Therapy for Metastatic Uveal Melanoma.

Tafreshi NK, Tichacek CJ, Pandya DN, Doligalski ML, Budzevich MM, Kil H, Bhatt NB, Kock ND, Messina JL, Ruiz EE, Delva NC, Weaver A, Gibbons WR, Boulware DC, Khushalani NI, El-Haddad G, Triozzi PL, Moros EG, McLaughlin ML, Wadas TJ, Morse DL.

J Nucl Med. 2019 Aug;60(8):1124-1133. doi: 10.2967/jnumed.118.217240. Epub 2019 Feb 7.


The hypoxic kidney: pathogenesis and noncoding RNA-based therapeutic strategies.

Haddad G, Kölling M, Lorenzen JM.

Swiss Med Wkly. 2019 Jan 13;149:w14703. doi: 10.4414/smw.2019.14703. eCollection 2019 Jan 1.


Lymphatic interventions for isolated, iatrogenic chylous ascites: A multi-institution experience.

Majdalany BS, Khayat M, Downing T, Killoran TP, El-Haddad G, Khaja MS, Saad WA.

Eur J Radiol. 2018 Dec;109:41-47. doi: 10.1016/j.ejrad.2018.10.019. Epub 2018 Oct 25.


Using the Albumin-Bilirubin (ALBI) grade as a prognostic marker for radioembolization of hepatocellular carcinoma.

Mohammadi H, Abuodeh Y, Jin W, Frakes J, Friedman M, Biebel B, Choi J, El-Haddad G, Kis B, Sweeney J, Hoffe S.

J Gastrointest Oncol. 2018 Oct;9(5):840-846. doi: 10.21037/jgo.2018.05.14.


Circulating miR-26a and miR-21 as biomarkers for glioblastoma multiform.

ParvizHamidi M, Haddad G, Ostadrahimi S, Ostadrahimi N, Sadeghi S, Fayaz S, Fard-Esfahani P.

Biotechnol Appl Biochem. 2019 Mar;66(2):261-265. doi: 10.1002/bab.1707. Epub 2018 Nov 19.


Biallelic Mutations in ADPRHL2, Encoding ADP-Ribosylhydrolase 3, Lead to a Degenerative Pediatric Stress-Induced Epileptic Ataxia Syndrome.

Ghosh SG, Becker K, Huang H, Dixon-Salazar T, Chai G, Salpietro V, Al-Gazali L, Waisfisz Q, Wang H, Vaux KK, Stanley V, Manole A, Akpulat U, Weiss MM, Efthymiou S, Hanna MG, Minetti C, Striano P, Pisciotta L, De Grandis E, Altmüller J, Nürnberg P, Thiele H, Yis U, Okur TD, Polat AI, Amiri N, Doosti M, Karimani EG, Toosi MB, Haddad G, Karakaya M, Wirth B, van Hagen JM, Wolf NI, Maroofian R, Houlden H, Cirak S, Gleeson JG.

Am J Hum Genet. 2018 Nov 1;103(5):826. doi: 10.1016/j.ajhg.2018.10.002. No abstract available.


Abuse and Effects of Salvia divinorum in a Sample of Patients Hospitalized for Substance Dependence.

Karam A, Said A, Assaad C, Hallit S, Haddad G, Hachem D, Kazour F.

Community Ment Health J. 2019 May;55(4):702-708. doi: 10.1007/s10597-018-0347-4. Epub 2018 Oct 29.


The validity and reliability of the CAMDEX-DS for assessing dementia in adults with Down syndrome in Brazil.

Fonseca LM, Haddad GG, Mattar GP, Oliveira MC, Simon SS, Guilhoto LM, Busatto GF, Zaman S, Holland AJ, Hoexter MQ, Bottino CM.

Braz J Psychiatry. 2019 May-Jun;41(3):225-233. doi: 10.1590/1516-4446-2018-0033. Epub 2018 Oct 22.


Regarding "A systematic review and meta-analysis of one-stage versus two-stage brachiobasilic arteriovenous fistula creation".

Kakkos SK, Tsolakis IA, Goumenos D, Haddad GK.

J Vasc Surg. 2018 Nov;68(5):1618-1619. doi: 10.1016/j.jvs.2018.07.047. No abstract available.


Novel insight into the genetic basis of high-altitude pulmonary hypertension in Kyrgyz highlanders.

Iranmehr A, Stobdan T, Zhou D, Poulsen O, Strohl KP, Aldashev A, Telenti A, Wong EHM, Kirkness EF, Venter JC, Bafna V, Haddad GG.

Eur J Hum Genet. 2019 Jan;27(1):150-159. doi: 10.1038/s41431-018-0270-8. Epub 2018 Sep 25.


Using microwave cooking to evaluate tenderness and its relationship to sensory analysis.

Silva DRG, Haddad GBS, Fontes PR, Holman BWB, Ramos ALS, Hopkins DL, Ramos EM.

J Texture Stud. 2018 Dec;49(6):612-618. doi: 10.1111/jtxs.12367. Epub 2018 Oct 7.


The Circular RNA ciRs-126 Predicts Survival in Critically Ill Patients With Acute Kidney Injury.

Kölling M, Seeger H, Haddad G, Kistler A, Nowak A, Faulhaber-Walter R, Kielstein J, Haller H, Fliser D, Mueller T, Wüthrich RP, Lorenzen JM.

Kidney Int Rep. 2018 Jun 2;3(5):1144-1152. doi: 10.1016/j.ekir.2018.05.012. eCollection 2018 Sep.


Managing acutely aggressive or agitated people in a psychiatric setting: a survey in Lebanon.

Dib JE, Adams CE, Kazour F, Tahan F, Haddad G, Haddad C, Hallit S.

Med J Islam Repub Iran. 2018 Jul 15;32:60. doi: 10.14196/mjiri.32.60. eCollection 2018.


miR-1266-5p and miR-185-5p Promote Cell Apoptosis in Human Prostate Cancer Cell Lines

Ostadrahimi S, Abedi Valugerdi M, Hassan M, Haddad G, Fayaz S, Parvizhamidi M, Mahdian R, Fard Esfahani P.

Asian Pac J Cancer Prev. 2018 Aug 24;19(8):2305-2311.


Biallelic Mutations in ADPRHL2, Encoding ADP-Ribosylhydrolase 3, Lead to a Degenerative Pediatric Stress-Induced Epileptic Ataxia Syndrome.

Ghosh SG, Becker K, Huang H, Dixon-Salazar T, Chai G, Salpietro V, Al-Gazali L, Waisfisz Q, Wang H, Vaux KK, Stanley V, Manole A, Akpulat U, Weiss MM, Efthymiou S, Hanna MG, Minetti C, Striano P, Pisciotta L, De Grandis E, Altmüller J, Nürnberg P, Thiele H, Yis U, Okur TD, Polat AI, Amiri N, Doosti M, Karimani EG, Toosi MB, Haddad G, Karakaya M, Wirth B, van Hagen JM, Wolf NI, Maroofian R, Houlden H, Cirak S, Gleeson JG.

Am J Hum Genet. 2018 Sep 6;103(3):431-439. doi: 10.1016/j.ajhg.2018.07.010. Epub 2018 Aug 9. Erratum in: Am J Hum Genet. 2018 Nov 1;103(5):826.


SCALP Syndrome associated with central nervous system melanoma.

Espósito ACC, Merlotto MR, Malzoni ML, Haddad GR, Stolf HO, Romero FR, Miot HA.

Int J Dermatol. 2019 May;58(5):614-615. doi: 10.1111/ijd.14163. Epub 2018 Aug 3. No abstract available.


Excision of basal cell carcinomas smaller than 1 cm with 2 mm safety margins: Lateral margin adequacy evaluated by double-bladed scalpel method.

Haddad GR, Miot HA, Alencar Marques ME, Schmitt JV.

Indian J Dermatol Venereol Leprol. 2018 Sep-Oct;84(5):603-606. doi: 10.4103/ijdvl.IJDVL_462_17. No abstract available.


Cardiac-specific knockout and pharmacological inhibition of Endothelin receptor type B lead to cardiac resistance to extreme hypoxia.

Stobdan T, Zhou D, Williams AT, Cabrales P, Haddad GG.

J Mol Med (Berl). 2018 Sep;96(9):975-982. doi: 10.1007/s00109-018-1673-2. Epub 2018 Aug 1.


Intrahepatic Cholangiocarcinoma Treated with Transarterial Yttrium-90 Glass Microsphere Radioembolization: Results of a Single Institution Retrospective Study.

Gangi A, Shah J, Hatfield N, Smith J, Sweeney J, Choi J, El-Haddad G, Biebel B, Parikh N, Arslan B, Hoffe SE, Frakes JM, Springett GM, Anaya DA, Malafa M, Chen DT, Chen Y, Kim RD, Shridhar R, Kis B.

J Vasc Interv Radiol. 2018 Aug;29(8):1101-1108. doi: 10.1016/j.jvir.2018.04.001. Epub 2018 Jul 2.


Exploring miRNA-mRNA regulatory network in cardiac pathology in Na+/H+ exchanger isoform 1 transgenic mice.

Xue J, Zhou D, Poulsen O, Hartley I, Imamura T, Xie EX, Haddad GG.

Physiol Genomics. 2018 Oct 1;50(10):846-861. doi: 10.1152/physiolgenomics.00048.2018. Epub 2018 Jul 20.


Viral hepatitis associated hepatocellular carcinoma outcomes with yttrium-90 radioembolization.

Frakes JM, Abuodeh YA, Naghavi AO, Echevarria MI, Shridhar R, Friedman M, Kim R, El-Haddad G, Kis B, Biebel B, Sweeney J, Choi J, Anaya D, Giuliano AR, Hoffe SE.

J Gastrointest Oncol. 2018 Jun;9(3):546-552. doi: 10.21037/jgo.2018.03.04.


Embolization-sclerotherapy of a refractory large volume post-operative pelvic lymphocele.

Addo E, Kong MJ, El-Haddad G.

Urol Case Rep. 2018 Jun 21;20:43-44. doi: 10.1016/j.eucr.2018.06.010. eCollection 2018 Sep. No abstract available.


Management of Pituitary Adenomas: Mononostril Endoscopic Transsphenoidal Surgery.

Darwish H, El-Hadi U, Haddad G, Najjar M.

Basic Clin Neurosci. 2018 Mar-Apr;9(2):121-128. doi: 10.29252/


Intermittent Hypoxia and Hypercapnia, a Hallmark of Obstructive Sleep Apnea, Alters the Gut Microbiome and Metabolome.

Tripathi A, Melnik AV, Xue J, Poulsen O, Meehan MJ, Humphrey G, Jiang L, Ackermann G, McDonald D, Zhou D, Knight R, Dorrestein PC, Haddad GG.

mSystems. 2018 Jun 5;3(3). pii: e00020-18. doi: 10.1128/mSystems.00020-18. eCollection 2018 May-Jun.


Alcoholism: A Multi-Systemic Cellular Insult to Organs.

Dguzeh U, Haddad NC, Smith KTS, Johnson JO, Doye AA, Gwathmey JK, Haddad GE.

Int J Environ Res Public Health. 2018 May 28;15(6). pii: E1083. doi: 10.3390/ijerph15061083. Review.


Biochemical profile of non-enzymatic stress markers in the plant species "Urginea maritima" in a Mediterranean natural reserve exposed to oxidative stress.

Khairallah Y, Houri T, Osta B, Romanos D, Haddad G.

Environ Monit Assess. 2018 May 22;190(6):354. doi: 10.1007/s10661-018-6729-9.


90Y Radioembolization for Hepatic Malignancy in Patients with Previous Biliary Intervention: Multicenter Analysis of Hepatobiliary Infections.

Devulapalli KK, Fidelman N, Soulen MC, Miller M, Johnson MS, Addo E, El-Haddad G, Nutting C, Morrison J, Farsad K, Lokken RP, Gaba RC, Fleming J, Brown DB, Kwan SW, Rose SC, Pennycooke KA, Liu DM, White SB, Gandhi R, Lazar AA, Kerlan RK Jr.

Radiology. 2018 Sep;288(3):774-781. doi: 10.1148/radiol.2018170962. Epub 2018 May 8.


Alcohol-Mediated Organ Damages: Heart and Brain.

Obad A, Peeran A, Little JI, Haddad GE, Tarzami ST.

Front Pharmacol. 2018 Feb 13;9:81. doi: 10.3389/fphar.2018.00081. eCollection 2018. Review.


Hypoxia-induced long non-coding RNA Malat1 is dispensable for renal ischemia/reperfusion-injury.

Kölling M, Genschel C, Kaucsar T, Hübner A, Rong S, Schmitt R, Sörensen-Zender I, Haddad G, Kistler A, Seeger H, Kielstein JT, Fliser D, Haller H, Wüthrich R, Zörnig M, Thum T, Lorenzen J.

Sci Rep. 2018 Feb 21;8(1):3438. doi: 10.1038/s41598-018-21720-3.


Intracellular pH Regulation in iPSCs-derived Astrocytes from Subjects with Chronic Mountain Sickness.

Yao H, Zhao H, Wang J, Haddad GG.

Neuroscience. 2018 Apr 1;375:25-33. doi: 10.1016/j.neuroscience.2018.02.008. Epub 2018 Feb 10.


Comparative Randomized Crossover Clinical Study for the Evaluation of Erectile Dysfunction Medications Via Novel Pentagon System.

Nounou MI, El Haddad G, El Amrawy F, El Gaddar O, El Yazbi A, Eshra A.

Curr Drug Saf. 2018;13(1):12-20. doi: 10.2174/1574886313666180122163322.


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