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Items: 1 to 50 of 75

1.

Positive STAT5 Protein and Locus Amplification Status Predicts Recurrence after Radical Prostatectomy to Assist Clinical Precision Management of Prostate Cancer.

Haddad BR, Erickson A, Udhane V, LaViolette PS, Rone JD, Kallajoki MA, See WA, Rannikko A, Mirtti T, Nevalainen MT.

Cancer Epidemiol Biomarkers Prev. 2019 Oct;28(10):1642-1651. doi: 10.1158/1055-9965.EPI-18-1358. Epub 2019 Jul 10.

PMID:
31292140
2.

Alterations in Cell Motility, Proliferation, and Metabolism in Novel Models of Acquired Temozolomide Resistant Glioblastoma.

Tiek DM, Rone JD, Graham GT, Pannkuk EL, Haddad BR, Riggins RB.

Sci Rep. 2018 May 8;8(1):7222. doi: 10.1038/s41598-018-25588-1.

3.

Expanding primary cells from mucoepidermoid and other salivary gland neoplasms for genetic and chemosensitivity testing.

Alamri AM, Liu X, Blancato JK, Haddad BR, Wang W, Zhong X, Choudhary S, Krawczyk E, Kallakury BV, Davidson BJ, Furth PA.

Dis Model Mech. 2018 Jan 29;11(1). pii: dmm031716. doi: 10.1242/dmm.031716.

4.

HPV positive neuroendocrine cervical cancer cells are dependent on Myc but not E6/E7 viral oncogenes.

Yuan H, Krawczyk E, Blancato J, Albanese C, Zhou D, Wang N, Paul S, Alkhilaiwi F, Palechor-Ceron N, Dakic A, Fang S, Choudhary S, Hou TW, Zheng YL, Haddad BR, Usuda Y, Hartmann D, Symer D, Gillison M, Agarwal S, Wangsa D, Ried T, Liu X, Schlegel R.

Sci Rep. 2017 Apr 5;7:45617. doi: 10.1038/srep45617.

5.

Metabolomic profiling of breast tumors using ductal fluid.

Matos Do Canto L, Marian C, Varghese RS, Ahn J, Da Cunha PA, Willey S, Sidawy M, Rone JD, Cheema AK, Luta G, Nezami Ranjbar MR, Ressom HW, Haddad BR.

Int J Oncol. 2016 Dec;49(6):2245-2254. doi: 10.3892/ijo.2016.3732. Epub 2016 Oct 13.

6.

MicroRNA analysis of breast ductal fluid in breast cancer patients.

Do Canto LM, Marian C, Willey S, Sidawy M, Da Cunha PA, Rone JD, Li X, Gusev Y, Haddad BR.

Int J Oncol. 2016 May;48(5):2071-8. doi: 10.3892/ijo.2016.3435. Epub 2016 Mar 10.

7.

Cell growth density modulates cancer cell vascular invasion via Hippo pathway activity and CXCR2 signaling.

Sharif GM, Schmidt MO, Yi C, Hu Z, Haddad BR, Glasgow E, Riegel AT, Wellstein A.

Oncogene. 2015 Nov 26;34(48):5879-89. doi: 10.1038/onc.2015.44. Epub 2015 Mar 16.

8.

Interferon regulatory factor-1 signaling regulates the switch between autophagy and apoptosis to determine breast cancer cell fate.

Schwartz-Roberts JL, Cook KL, Chen C, Shajahan-Haq AN, Axelrod M, Wärri A, Riggins RB, Jin L, Haddad BR, Kallakury BV, Baumann WT, Clarke R.

Cancer Res. 2015 Mar 15;75(6):1046-55. doi: 10.1158/0008-5472.CAN-14-1851. Epub 2015 Jan 9.

9.

Increased copy number of the DLX4 homeobox gene in breast axillary lymph node metastasis.

Torresan C, Oliveira MM, Pereira SR, Ribeiro EM, Marian C, Gusev Y, Lima RS, Urban CA, Berg PE, Haddad BR, Cavalli IJ, Cavalli LR.

Cancer Genet. 2014 May;207(5):177-87. doi: 10.1016/j.cancergen.2014.04.007. Epub 2014 May 2.

10.

Genome-wide multi-omics profiling of colorectal cancer identifies immune determinants strongly associated with relapse.

Madhavan S, Gusev Y, Natarajan TG, Song L, Bhuvaneshwar K, Gauba R, Pandey A, Haddad BR, Goerlitz D, Cheema AK, Juhl H, Kallakury B, Marshall JL, Byers SW, Weiner LM.

Front Genet. 2013 Nov 20;4:236. doi: 10.3389/fgene.2013.00236. eCollection 2013.

11.

Striking similarities in genetic aberrations between a rectal tumor and its lung recurrence.

Rahma OE, Burotto M, Do Canto LM, Germanos AA, Haddad BR, Marshall JL.

World J Gastrointest Oncol. 2013 Nov 15;5(11):198-203. doi: 10.4251/wjgo.v5.i11.198.

12.

STAT5A/B gene locus undergoes amplification during human prostate cancer progression.

Haddad BR, Gu L, Mirtti T, Dagvadorj A, Vogiatzi P, Hoang DT, Bajaj R, Leiby B, Ellsworth E, Blackmon S, Ruiz C, Curtis M, Fortina P, Ertel A, Liu C, Rui H, Visakorpi T, Bubendorf L, Lallas CD, Trabulsi EJ, McCue P, Gomella L, Nevalainen MT.

Am J Pathol. 2013 Jun;182(6):2264-75. doi: 10.1016/j.ajpath.2013.02.044. Epub 2013 May 7.

13.

ROCK inhibitor and feeder cells induce the conditional reprogramming of epithelial cells.

Liu X, Ory V, Chapman S, Yuan H, Albanese C, Kallakury B, Timofeeva OA, Nealon C, Dakic A, Simic V, Haddad BR, Rhim JS, Dritschilo A, Riegel A, McBride A, Schlegel R.

Am J Pathol. 2012 Feb;180(2):599-607. doi: 10.1016/j.ajpath.2011.10.036. Epub 2011 Dec 18.

14.

Frequent loss of the BLID gene in early-onset breast cancer.

Cavalli LR, Noone AM, Makambi KH, Rone JD, Kasid UN, Haddad BR.

Cytogenet Genome Res. 2011;135(1):19-24. doi: 10.1159/000330265. Epub 2011 Aug 12.

15.

Radiation-generated short DNA fragments may perturb non-homologous end-joining and induce genomic instability.

Pang D, Winters TA, Jung M, Purkayastha S, Cavalli LR, Chasovkikh S, Haddad BR, Dritschilo A.

J Radiat Res. 2011;52(3):309-19.

16.

The proapoptotic molecule BLID interacts with Bcl-XL and its downregulation in breast cancer correlates with poor disease-free and overall survival.

Broustas CG, Ross JS, Yang Q, Sheehan CE, Riggins R, Noone AM, Haddad BR, Seillier-Moiseiwitsch F, Kallakury BV, Haffty BG, Clarke R, Kasid UN.

Clin Cancer Res. 2010 Jun 1;16(11):2939-48. doi: 10.1158/1078-0432.CCR-09-2351. Epub 2010 Apr 16.

17.

TGIF Mutations in Human Holoprosencephaly: Correlation between Genotype and Phenotype.

Keaton AA, Solomon BD, Kauvar EF, El-Jaick KB, Gropman AL, Zafer Y, Meck JM, Bale SJ, Grange DK, Haddad BR, Gowans GC, Clegg NJ, Delgado MR, Hahn JS, Pineda-Alvarez DE, Lacbawan F, Vélez JI, Roessler E, Muenke M.

Mol Syndromol. 2010;1(5):211-222. Epub 2011 May 18.

18.

Cooperation of tumor-derived HBx mutants and p53-249(ser) mutant in regulating cell proliferation, anchorage-independent growth and aneuploidy in a telomerase-immortalized normal human hepatocyte-derived cell line.

Jiang W, Wang XW, Unger T, Forgues M, Kim JW, Hussain SP, Bowman E, Spillare EA, Lipsky MM, Meck JM, Cavalli LR, Haddad BR, Harris CC.

Int J Cancer. 2010 Sep 1;127(5):1011-20. doi: 10.1002/ijc.25118.

19.

BRCA1 localization to the telomere and its loss from the telomere in response to DNA damage.

Ballal RD, Saha T, Fan S, Haddad BR, Rosen EM.

J Biol Chem. 2009 Dec 25;284(52):36083-98. doi: 10.1074/jbc.M109.025825. Epub 2009 Sep 21.

20.

Frequent loss of heterozygosity at the interferon regulatory factor-1 gene locus in breast cancer.

Cavalli LR, Riggins RB, Wang A, Clarke R, Haddad BR.

Breast Cancer Res Treat. 2010 May;121(1):227-31. doi: 10.1007/s10549-009-0509-8. Epub 2009 Aug 21.

21.

Pluripotent stem cells derived from adult human testes.

Golestaneh N, Kokkinaki M, Pant D, Jiang J, DeStefano D, Fernandez-Bueno C, Rone JD, Haddad BR, Gallicano GI, Dym M.

Stem Cells Dev. 2009 Oct;18(8):1115-26. doi: 10.1089/scd.2008.0347.

22.

Amplification of the BP1 homeobox gene in breast cancer.

Cavalli LR, Man YG, Schwartz AM, Rone JD, Zhang Y, Urban CA, Lima RS, Haddad BR, Berg PE.

Cancer Genet Cytogenet. 2008 Nov;187(1):19-24. doi: 10.1016/j.cancergencyto.2008.07.004.

23.

ERRgamma mediates tamoxifen resistance in novel models of invasive lobular breast cancer.

Riggins RB, Lan JP, Zhu Y, Klimach U, Zwart A, Cavalli LR, Haddad BR, Chen L, Gong T, Xuan J, Ethier SP, Clarke R.

Cancer Res. 2008 Nov 1;68(21):8908-17. doi: 10.1158/0008-5472.CAN-08-2669. Erratum in: Cancer Res. 2009 Feb 15;69(4):1695. Zhu, Yuelin [added].

24.

Assignment of the BLID gene to 11q24.1 by fluorescence in situ hybridization.

Cavalli LR, Santos SC, Broustas CG, Rone JD, Kasid UN, Haddad BR.

Cancer Genet Cytogenet. 2008 Oct 15;186(2):120-1. doi: 10.1016/j.cancergencyto.2008.06.011. No abstract available.

25.

Patterns of DNA copy number changes in sentinel lymph node breast cancer metastases.

Santos SC, Cavalli IJ, Ribeiro EM, Urban CA, Lima RS, Bleggi-Torres LF, Rone JD, Haddad BR, Cavalli LR.

Cytogenet Genome Res. 2008;122(1):16-21. doi: 10.1159/000151311. Epub 2008 Oct 14.

PMID:
18931481
26.

Androgen-regulated and highly tumorigenic human prostate cancer cell line established from a transplantable primary CWR22 tumor.

Dagvadorj A, Tan SH, Liao Z, Cavalli LR, Haddad BR, Nevalainen MT.

Clin Cancer Res. 2008 Oct 1;14(19):6062-72. doi: 10.1158/1078-0432.CCR-08-0979.

27.

Immortalization and transformation of human mammary epithelial cells by a tumor-derived Myc mutant.

Thibodeaux CA, Liu X, Disbrow GL, Zhang Y, Rone JD, Haddad BR, Schlegel R.

Breast Cancer Res Treat. 2009 Jul;116(2):281-94. doi: 10.1007/s10549-008-0127-x. Epub 2008 Jul 20.

28.

Downregulation of histone H3 lysine 9 methyltransferase G9a induces centrosome disruption and chromosome instability in cancer cells.

Kondo Y, Shen L, Ahmed S, Boumber Y, Sekido Y, Haddad BR, Issa JP.

PLoS One. 2008 Apr 30;3(4):e2037. doi: 10.1371/journal.pone.0002037.

29.

Holoprosencephaly-Polydactyly syndrome: in search of an etiology.

Cordero DR, Bendavid C, Shanske AL, Haddad BR, Muenke M.

Eur J Med Genet. 2008 Mar-Apr;51(2):106-12. doi: 10.1016/j.ejmg.2007.08.004. Epub 2007 Sep 15.

30.

Prenatal diagnosis of supernumerary ring chromosome 1: case report and review of the literature.

Wray AM, Dennis TR, Ghidini A, Gorman B, Haddad BR, Meck JM.

Genet Couns. 2007;18(2):233-41. Review.

PMID:
17710876
31.

Expression of BRCC3, a novel cell cycle regulated molecule, is associated with increased phospho-ERK and cell proliferation.

Boudreau HE, Broustas CG, Gokhale PC, Kumar D, Mewani RR, Rone JD, Haddad BR, Kasid U.

Int J Mol Med. 2007 Jan;19(1):29-39.

PMID:
17143545
32.

MDA-MB-435 cells are derived from M14 melanoma cells--a loss for breast cancer, but a boon for melanoma research.

Rae JM, Creighton CJ, Meck JM, Haddad BR, Johnson MD.

Breast Cancer Res Treat. 2007 Jul;104(1):13-9. Epub 2006 Sep 27.

PMID:
17004106
33.

SF-1 overexpression in childhood adrenocortical tumours.

Pianovski MA, Cavalli LR, Figueiredo BC, Santos SC, Doghman M, Ribeiro RC, Oliveira AG, Michalkiewicz E, Rodrigues GA, Zambetti G, Haddad BR, Lalli E.

Eur J Cancer. 2006 May;42(8):1040-3. Epub 2006 Mar 29.

PMID:
16574405
34.

Neuroblastoma in southern Brazil: an 11-year study.

Parise IZ, Haddad BR, Cavalli LR, Pianovski MA, Maggio EM, Parise GA, Watanabe FM, Ioshii SO, Rone JD, Caleffe LG, Odone Filho V, Figueiredo BC.

J Pediatr Hematol Oncol. 2006 Feb;28(2):82-7.

PMID:
16462579
35.
36.

Molecular evaluation of foetuses with holoprosencephaly shows high incidence of microdeletions in the HPE genes.

Bendavid C, Dubourg C, Gicquel I, Pasquier L, Saugier-Veber P, Durou MR, Jaillard S, Frébourg T, Haddad BR, Henry C, Odent S, David V.

Hum Genet. 2006 Mar;119(1-2):1-8. Epub 2005 Dec 2.

PMID:
16323008
37.

Multicolour FISH and quantitative PCR can detect submicroscopic deletions in holoprosencephaly patients with a normal karyotype.

Bendavid C, Haddad BR, Griffin A, Huizing M, Dubourg C, Gicquel I, Cavalli LR, Pasquier L, Shanske AL, Long R, Ouspenskaia M, Odent S, Lacbawan F, David V, Muenke M.

J Med Genet. 2006 Jun;43(6):496-500. Epub 2005 Sep 30.

38.

Haploinsufficiency of cytochrome P450 17alpha-hydroxylase/17,20 lyase (CYP17) causes infertility in male mice.

Liu Y, Yao ZX, Bendavid C, Borgmeyer C, Han Z, Cavalli LR, Chan WY, Folmer J, Zirkin BR, Haddad BR, Gallicano GI, Papadopoulos V.

Mol Endocrinol. 2005 Sep;19(9):2380-9. Epub 2005 May 12.

PMID:
15890676
39.

Deletion, methylation, and expression of the NKX3.1 suppressor gene in primary human prostate cancer.

Asatiani E, Huang WX, Wang A, Rodriguez Ortner E, Cavalli LR, Haddad BR, Gelmann EP.

Cancer Res. 2005 Feb 15;65(4):1164-73.

40.

A pilot study to establish a clinical model to perform phase II studies of breast cancer chemopreventive agents in women at high risk with biomarkers as surrogate endpoints for activity.

Stearns V, Gallagher A, Kleer CG, Singh B, Freedman M, Haddad BR, Isaacs C, Warren R, Brown M, Cullen J, Trock B, Hayes DF.

Clin Cancer Res. 2004 Dec 15;10(24):8332-40.

41.

Amplification of the steroidogenic factor 1 gene in childhood adrenocortical tumors.

Figueiredo BC, Cavalli LR, Pianovski MA, Lalli E, Sandrini R, Ribeiro RC, Zambetti G, DeLacerda L, Rodrigues GA, Haddad BR.

J Clin Endocrinol Metab. 2005 Feb;90(2):615-9. Epub 2004 Nov 16.

PMID:
15546904
42.

Overexpression of the nuclear receptor coactivator AIB1 (SRC-3) during progression of pancreatic adenocarcinoma.

Henke RT, Haddad BR, Kim SE, Rone JD, Mani A, Jessup JM, Wellstein A, Maitra A, Riegel AT.

Clin Cancer Res. 2004 Sep 15;10(18 Pt 1):6134-42.

43.

FISH diagnosis of the common 57-kb deletion in CTNS causing cystinosis.

Bendavid C, Kleta R, Long R, Ouspenskaia M, Muenke M, Haddad BR, Gahl WA.

Hum Genet. 2004 Nov;115(6):510-4. Epub 2004 Sep 9.

PMID:
15365816
44.

Lack of DNA copy number alterations revealed with comparative genomic hybridization in fibroadenomas of the breast.

Cavalli LR, Cornelio DA, Lima RS, Urban CA, Rone JD, Cavalli IJ, Haddad BR.

Cancer Genet Cytogenet. 2004 Sep;153(2):173-6.

PMID:
15350309
45.

Hormone-induced chromosomal instability in p53-null mammary epithelium.

Pati D, Haddad BR, Haegele A, Thompson H, Kittrell FS, Shepard A, Montagna C, Zhang N, Ge G, Otta SK, McCarthy M, Ullrich RL, Medina D.

Cancer Res. 2004 Aug 15;64(16):5608-16.

46.

High frequency of t(12;21)(p13;q22) in children with acute lymphoblastic leukemia and known clinical outcome in southern Brazil.

Veiga LB, Cóser VM, Cavalli LR, Cavalli IJ, Rodrigues JN, Pereira WV, Pereira DV, Lafayette TC, Villalba BT, Moreira ME, Haddad BR, de Souza Fonseca Ribeiro EM.

Leuk Res. 2004 Oct;28(10):1033-8.

PMID:
15289014
47.

Loss of heterozygosity in normal breast epithelial tissue and benign breast lesions in BRCA1/2 carriers with breast cancer.

Cavalli LR, Singh B, Isaacs C, Dickson RB, Haddad BR.

Cancer Genet Cytogenet. 2004 Feb;149(1):38-43.

PMID:
15104281
48.

Loss of heterozygosity of the BRCA1 and FHIT genes in patients with sporadic breast cancer from Southern Brazil.

Santos SC, Cavalli LR, Cavalli IJ, Lima RS, Haddad BR, Ribeiro EM.

J Clin Pathol. 2004 Apr;57(4):374-7.

49.

Detection of LOH and mitochondrial DNA alterations in ductal lavage and nipple aspirate fluids from hngh-risk patients.

Isaacs C, Cavalli LR, Cohen Y, Pennanen M, Shankar LK, Freedman M, Singh B, Liu M, Gallagher A, Rone JD, Dickson RB, Sidransky D, Haddad BR.

Breast Cancer Res Treat. 2004 Mar;84(2):99-105.

PMID:
14999140
50.

Glutathione S-transferase pi amplification is associated with cisplatin resistance in head and neck squamous cell carcinoma cell lines and primary tumors.

Cullen KJ, Newkirk KA, Schumaker LM, Aldosari N, Rone JD, Haddad BR.

Cancer Res. 2003 Dec 1;63(23):8097-102.

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