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Items: 45

1.

Novel Targets for Therapy of Renal Fibrosis.

Prakoura N, Hadchouel J, Chatziantoniou C.

J Histochem Cytochem. 2019 Sep;67(9):701-715. doi: 10.1369/0022155419849386. Epub 2019 May 22.

PMID:
31116064
2.

Severe Arterial Hypertension from Cullin 3 Mutations Is Caused by Both Renal and Vascular Effects.

Abdel Khalek W, Rafael C, Loisel-Ferreira I, Kouranti I, Clauser E, Hadchouel J, Jeunemaitre X.

J Am Soc Nephrol. 2019 May;30(5):811-823. doi: 10.1681/ASN.2017121307. Epub 2019 Apr 9.

PMID:
30967423
3.

A mouse model of pseudohypoaldosteronism type II reveals a novel mechanism of renal tubular acidosis.

López-Cayuqueo KI, Chavez-Canales M, Pillot A, Houillier P, Jayat M, Baraka-Vidot J, Trepiccione F, Baudrie V, Büsst C, Soukaseum C, Kumai Y, Jeunemaître X, Hadchouel J, Eladari D, Chambrey R.

Kidney Int. 2018 Sep;94(3):514-523. doi: 10.1016/j.kint.2018.05.001. Epub 2018 Jul 7.

PMID:
30146013
4.

Kidney-specific WNK1 isoform (KS-WNK1) is a potent activator of WNK4 and NCC.

Argaiz ER, Chavez-Canales M, Ostrosky-Frid M, Rodríguez-Gama A, Vázquez N, Gonzalez-Rodriguez X, Garcia-Valdes J, Hadchouel J, Ellison D, Gamba G.

Am J Physiol Renal Physiol. 2018 Sep 1;315(3):F734-F745. doi: 10.1152/ajprenal.00145.2018. Epub 2018 May 30.

5.

Role of WNK4 and kidney-specific WNK1 in mediating the effect of high dietary K+ intake on ROMK channel in the distal convoluted tubule.

Wu P, Gao ZX, Su XT, Ellison DH, Hadchouel J, Teulon J, Wang WH.

Am J Physiol Renal Physiol. 2018 Aug 1;315(2):F223-F230. doi: 10.1152/ajprenal.00050.2018. Epub 2018 Apr 18.

6.

Consequences of SPAK inactivation on Hyperkalemic Hypertension caused by WNK1 mutations: evidence for differential roles of WNK1 and WNK4.

Rafael C, Soukaseum C, Baudrie V, Frère P, Hadchouel J.

Sci Rep. 2018 Feb 19;8(1):3249. doi: 10.1038/s41598-018-21405-x.

7.

Acute genetic ablation of pendrin lowers blood pressure in mice.

Trepiccione F, Soukaseum C, Baudrie V, Kumai Y, Teulon J, Villoutreix B, Cornière N, Wangemann P, Griffith AJ, Byung Choi Y, Hadchouel J, Chambrey R, Eladari D.

Nephrol Dial Transplant. 2017 Jul 1;32(7):1137-1145. doi: 10.1093/ndt/gfw393.

8.

A fate-mapping approach reveals the composite origin of the connecting tubule and alerts on "single-cell"-specific KO model of the distal nephron.

Trepiccione F, Soukaseum C, Iervolino A, Petrillo F, Zacchia M, Schutz G, Eladari D, Capasso G, Hadchouel J.

Am J Physiol Renal Physiol. 2016 Nov 1;311(5):F901-F906. doi: 10.1152/ajprenal.00286.2016. Epub 2016 Aug 31.

9.

With no lysine L-WNK1 isoforms are negative regulators of the K+-Cl- cotransporters.

Mercado A, de Los Heros P, Melo Z, Chávez-Canales M, Murillo-de-Ozores AR, Moreno E, Bazúa-Valenti S, Vázquez N, Hadchouel J, Gamba G.

Am J Physiol Cell Physiol. 2016 Jul 1;311(1):C54-66. doi: 10.1152/ajpcell.00193.2015. Epub 2016 May 11.

10.

Double Knockout of the Na+-Driven Cl-/HCO3- Exchanger and Na+/Cl- Cotransporter Induces Hypokalemia and Volume Depletion.

Sinning A, Radionov N, Trepiccione F, López-Cayuqueo KI, Jayat M, Baron S, Cornière N, Alexander RT, Hadchouel J, Eladari D, Hübner CA, Chambrey R.

J Am Soc Nephrol. 2017 Jan;28(1):130-139. doi: 10.1681/ASN.2015070734. Epub 2016 May 5.

11.

[New perspective on the role of WNK1 and WNK4 in the regulation of NaCl reabsorption and K(+) secretion by the distal nephron].

Rafael C, Chavez-Canales M, Hadchouel J.

Med Sci (Paris). 2016 Mar;32(3):274-80. doi: 10.1051/medsci/20163203012. Epub 2016 Mar 23. Review. French.

12.

Regulation of Renal Electrolyte Transport by WNK and SPAK-OSR1 Kinases.

Hadchouel J, Ellison DH, Gamba G.

Annu Rev Physiol. 2016;78:367-89. doi: 10.1146/annurev-physiol-021115-105431. Review.

PMID:
26863326
13.

Degradation by Cullin 3 and effect on WNK kinases suggest a role of KLHL2 in the pathogenesis of Familial Hyperkalemic Hypertension.

Zhang C, Meermeier NP, Terker AS, Blankenstein KI, Singer JD, Hadchouel J, Ellison DH, Yang CL.

Biochem Biophys Res Commun. 2016 Jan 1;469(1):44-48. doi: 10.1016/j.bbrc.2015.11.067. Epub 2015 Nov 23.

14.

PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension.

Berger JM, Vaillant N, Le May C, Calderon C, Brégeon J, Prieur X, Hadchouel J, Loirand G, Cariou B.

Atherosclerosis. 2015 Mar;239(1):252-9. doi: 10.1016/j.atherosclerosis.2015.01.012. Epub 2015 Jan 19.

PMID:
25621930
15.

Ovarian hormones and prolactin increase renal NaCl cotransporter phosphorylation.

Rojas-Vega L, Reyes-Castro LA, Ramírez V, Bautista-Pérez R, Rafael C, Castañeda-Bueno M, Meade P, de Los Heros P, Arroyo-Garza I, Bernard V, Binart N, Bobadilla NA, Hadchouel J, Zambrano E, Gamba G.

Am J Physiol Renal Physiol. 2015 Apr 15;308(8):F799-808. doi: 10.1152/ajprenal.00447.2014. Epub 2015 Jan 13.

16.

The Effect of WNK4 on the Na+-Cl- Cotransporter Is Modulated by Intracellular Chloride.

Bazúa-Valenti S, Chávez-Canales M, Rojas-Vega L, González-Rodríguez X, Vázquez N, Rodríguez-Gama A, Argaiz ER, Melo Z, Plata C, Ellison DH, García-Valdés J, Hadchouel J, Gamba G.

J Am Soc Nephrol. 2015 Aug;26(8):1781-6. doi: 10.1681/ASN.2014050470. Epub 2014 Dec 26.

17.

WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4.

Chávez-Canales M, Zhang C, Soukaseum C, Moreno E, Pacheco-Alvarez D, Vidal-Petiot E, Castañeda-Bueno M, Vázquez N, Rojas-Vega L, Meermeier NP, Rogers S, Jeunemaitre X, Yang CL, Ellison DH, Gamba G, Hadchouel J.

Hypertension. 2014 Nov;64(5):1047-53. doi: 10.1161/HYPERTENSIONAHA.114.04036. Epub 2014 Aug 11.

18.

Electroneutral absorption of NaCl by the aldosterone-sensitive distal nephron: implication for normal electrolytes homeostasis and blood pressure regulation.

Eladari D, Chambrey R, Picard N, Hadchouel J.

Cell Mol Life Sci. 2014 Aug;71(15):2879-95. doi: 10.1007/s00018-014-1585-4. Epub 2014 Feb 21. Review.

PMID:
24556999
19.

WNK1-related Familial Hyperkalemic Hypertension results from an increased expression of L-WNK1 specifically in the distal nephron.

Vidal-Petiot E, Elvira-Matelot E, Mutig K, Soukaseum C, Baudrie V, Wu S, Cheval L, Huc E, Cambillau M, Bachmann S, Doucet A, Jeunemaitre X, Hadchouel J.

Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14366-71. doi: 10.1073/pnas.1304230110. Epub 2013 Aug 12.

20.

[KLHL3 and CULLIN-3: new genes involved in familial hypertension].

Louis-Dit-Picard H, Hadchouel J, Jeunemaitre X.

Med Sci (Paris). 2012 Aug-Sep;28(8-9):703-6. doi: 10.1051/medsci/2012288010. Epub 2012 Aug 22. French. No abstract available.

21.

A new methodology for quantification of alternatively spliced exons reveals a highly tissue-specific expression pattern of WNK1 isoforms.

Vidal-Petiot E, Cheval L, Faugeroux J, Malard T, Doucet A, Jeunemaitre X, Hadchouel J.

PLoS One. 2012;7(5):e37751. doi: 10.1371/journal.pone.0037751. Epub 2012 May 31.

22.

KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron.

Louis-Dit-Picard H, Barc J, Trujillano D, Miserey-Lenkei S, Bouatia-Naji N, Pylypenko O, Beaurain G, Bonnefond A, Sand O, Simian C, Vidal-Petiot E, Soukaseum C, Mandet C, Broux F, Chabre O, Delahousse M, Esnault V, Fiquet B, Houillier P, Bagnis CI, Koenig J, Konrad M, Landais P, Mourani C, Niaudet P, Probst V, Thauvin C, Unwin RJ, Soroka SD, Ehret G, Ossowski S, Caulfield M; International Consortium for Blood Pressure (ICBP), Bruneval P, Estivill X, Froguel P, Hadchouel J, Schott JJ, Jeunemaitre X.

Nat Genet. 2012 Mar 11;44(4):456-60, S1-3. doi: 10.1038/ng.2218. Erratum in: Nat Genet. 2012;44(5):609.

PMID:
22406640
23.

Regulation of extracellular fluid volume and blood pressure by pendrin.

Hadchouel J, Büsst C, Procino G, Valenti G, Chambrey R, Eladari D.

Cell Physiol Biochem. 2011;28(3):505-12. doi: 10.1159/000335116. Epub 2011 Nov 18. Review.

24.

Pathogenesis of pseudohypoaldosteronism type 2 by WNK1 mutations.

Bergaya S, Vidal-Petiot E, Jeunemaitre X, Hadchouel J.

Curr Opin Nephrol Hypertens. 2012 Jan;21(1):39-45. doi: 10.1097/MNH.0b013e32834d2fde. Review.

PMID:
22080857
25.

WNK1 regulates vasoconstriction and blood pressure response to α 1-adrenergic stimulation in mice.

Bergaya S, Faure S, Baudrie V, Rio M, Escoubet B, Bonnin P, Henrion D, Loirand G, Achard JM, Jeunemaitre X, Hadchouel J.

Hypertension. 2011 Sep;58(3):439-45. doi: 10.1161/HYPERTENSIONAHA.111.172429. Epub 2011 Jul 18.

PMID:
21768522
26.

Regulation of ion transport by microRNAs.

Elvira-Matelot E, Jeunemaitre X, Hadchouel J.

Curr Opin Nephrol Hypertens. 2011 Sep;20(5):541-6. doi: 10.1097/MNH.0b013e328348b4aa. Review.

PMID:
21670673
27.

Decreased ENaC expression compensates the increased NCC activity following inactivation of the kidney-specific isoform of WNK1 and prevents hypertension.

Hadchouel J, Soukaseum C, Büsst C, Zhou XO, Baudrie V, Zürrer T, Cambillau M, Elghozi JL, Lifton RP, Loffing J, Jeunemaitre X.

Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18109-14. doi: 10.1073/pnas.1006128107. Epub 2010 Oct 4.

28.

Regulation of WNK1 expression by miR-192 and aldosterone.

Elvira-Matelot E, Zhou XO, Farman N, Beaurain G, Henrion-Caude A, Hadchouel J, Jeunemaitre X.

J Am Soc Nephrol. 2010 Oct;21(10):1724-31. doi: 10.1681/ASN.2009111186. Epub 2010 Sep 2.

29.

Deletion of WNK1 first intron results in misregulation of both isoforms in renal and extrarenal tissues.

Delaloy C, Elvira-Matelot E, Clemessy M, Zhou XO, Imbert-Teboul M, Houot AM, Jeunemaitre X, Hadchouel J.

Hypertension. 2008 Dec;52(6):1149-54. doi: 10.1161/HYPERTENSIONAHA.108.120899. Epub 2008 Oct 27.

PMID:
18955660
30.

Life and death of the distal nephron: WNK4 and NCC as major players.

Hadchouel J, Jeunemaitre X.

Cell Metab. 2006 Nov;4(5):335-7. Review.

31.

Cardiovascular expression of the mouse WNK1 gene during development and adulthood revealed by a BAC reporter assay.

Delaloy C, Hadchouel J, Imbert-Teboul M, Clemessy M, Houot AM, Jeunemaitre X.

Am J Pathol. 2006 Jul;169(1):105-18.

32.

Inherited sodium avid states.

Achard JM, Hadchouel J, Faure S, Jeunemaitre X.

Adv Chronic Kidney Dis. 2006 Apr;13(2):118-23. Review.

PMID:
16580612
33.

Rotation of the myocardial wall of the outflow tract is implicated in the normal positioning of the great arteries.

Bajolle F, Zaffran S, Kelly RG, Hadchouel J, Bonnet D, Brown NA, Buckingham ME.

Circ Res. 2006 Feb 17;98(3):421-8. Epub 2006 Jan 5.

PMID:
16397144
34.

Familial hyperkalemic hypertension.

Hadchouel J, Delaloy C, Fauré S, Achard JM, Jeunemaitre X.

J Am Soc Nephrol. 2006 Jan;17(1):208-17. Epub 2005 Oct 12. Review. No abstract available.

35.

With-no-lysine kinases: the discovery of a new pathway in hypertension using human genetic studies.

Delaloy C, Hadchouel J, Jeunemaitre X.

Hypertension. 2005 Aug;46(2):263-4. Epub 2005 Jul 5. No abstract available.

PMID:
15998705
36.

[WNK1 and WNK4, new players in salt and water homeostasis].

Hadchouel J, Delaloy C, Jeunemaitre X.

Med Sci (Paris). 2005 Jan;21(1):55-60. Review. French.

37.

An enhancer directs differential expression of the linked Mrf4 and Myf5 myogenic regulatory genes in the mouse.

Chang TH, Primig M, Hadchouel J, Tajbakhsh S, Rocancourt D, Fernandez A, Kappler R, Scherthan H, Buckingham M.

Dev Biol. 2004 May 15;269(2):595-608.

38.

WNK kinases, distal tubular ion handling and hypertension.

Faure S, Delaloy C, Leprivey V, Hadchouel J, Warnock DG, Jeunemaitre X, Achard JM.

Nephrol Dial Transplant. 2003 Dec;18(12):2463-7. Review. No abstract available.

PMID:
14605263
39.

Analysis of a key regulatory region upstream of the Myf5 gene reveals multiple phases of myogenesis, orchestrated at each site by a combination of elements dispersed throughout the locus.

Hadchouel J, Carvajal JJ, Daubas P, Bajard L, Chang T, Rocancourt D, Cox D, Summerbell D, Tajbakhsh S, Rigby PW, Buckingham M.

Development. 2003 Aug;130(15):3415-26.

40.

The formation of skeletal muscle: from somite to limb.

Buckingham M, Bajard L, Chang T, Daubas P, Hadchouel J, Meilhac S, Montarras D, Rocancourt D, Relaix F.

J Anat. 2003 Jan;202(1):59-68. Review.

41.
42.

Modular long-range regulation of Myf5 reveals unexpected heterogeneity between skeletal muscles in the mouse embryo.

Hadchouel J, Tajbakhsh S, Primig M, Chang TH, Daubas P, Rocancourt D, Buckingham M.

Development. 2000 Oct;127(20):4455-67.

43.

Myf5 is a novel early axonal marker in the mouse brain and is subjected to post-transcriptional regulation in neurons.

Daubas P, Tajbakhsh S, Hadchouel J, Primig M, Buckingham M.

Development. 2000 Jan;127(2):319-31.

44.

A recombinant E1-deleted canine adenoviral vector capable of transduction and expression of a transgene in human-derived cells and in vivo.

Klonjkowski B, Gilardi-Hebenstreit P, Hadchouel J, Randrianarison V, Boutin S, Yeh P, Perricaudet M, Kremer EJ.

Hum Gene Ther. 1997 Nov 20;8(17):2103-15.

PMID:
9414258

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