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Items: 1 to 50 of 83

1.

Diacylglycerol kinase ζ promotes allergic airway inflammation and airway hyperresponsiveness through distinct mechanisms.

Singh BK, Lu W, Schmidt Paustian AM, Ge MQ, Koziol-White CJ, Flayer CH, Killingbeck SS, Wang N, Dong X, Riese MJ, Deshpande DA, Panettieri RA Jr, Haczku A, Kambayashi T.

Sci Signal. 2019 Sep 3;12(597). pii: eaax3332. doi: 10.1126/scisignal.aax3332.

PMID:
31481522
2.

Viruses and non-allergen environmental triggers in asthma.

Chau-Etchepare F, Hoerger JL, Kuhn BT, Zeki AA, Haczku A, Louie S, Kenyon NJ, Davis CE, Schivo M.

J Investig Med. 2019 Jul 27. pii: jim-2019-001000. doi: 10.1136/jim-2019-001000. [Epub ahead of print]

PMID:
31352362
3.

A burning need to redefine airways disease: Biomass smoke exposure identified as a unique risk factor for asthma-chronic obstructive pulmonary disease overlap in low- and middle-income countries.

Zeki AA, Flayer CH, Haczku A.

J Allergy Clin Immunol. 2019 Apr;143(4):1339-1341. doi: 10.1016/j.jaci.2018.11.020. Epub 2018 Dec 5. No abstract available.

PMID:
30529450
4.

Oxidative damage of SP-D abolishes control of eosinophil extracellular DNA trap formation.

Yousefi S, Sharma SK, Stojkov D, Germic N, Aeschlimann S, Ge MQ, Flayer CH, Larson ED, Redai IG, Zhang S, Koziol-White CJ, Karikó K, Simon HU, Haczku A.

J Leukoc Biol. 2018 Jul;104(1):205-214. doi: 10.1002/JLB.3AB1117-455R. Epub 2018 May 7.

5.

Group 2 innate lymphoid cells promote airway hyperresponsiveness through production of VEGFA.

Shen X, Pasha MA, Hidde K, Khan A, Liang M, Guan W, Ding Y, Haczku A, Yang Q.

J Allergy Clin Immunol. 2018 May;141(5):1929-1931.e4. doi: 10.1016/j.jaci.2018.01.005. Epub 2018 Jan 31. No abstract available.

6.

Breaking Steroid Resistance: Effect of Vitamin D on IL-23.

Flayer CH, Larson ED, Haczku A.

Am J Respir Cell Mol Biol. 2017 Sep;57(3):267-269. doi: 10.1165/rcmb.2017-0199ED. No abstract available.

7.

Glucagon-like peptide 1: A potential anti-inflammatory pathway in obesity-related asthma.

Nguyen DV, Linderholm A, Haczku A, Kenyon N.

Pharmacol Ther. 2017 Dec;180:139-143. doi: 10.1016/j.pharmthera.2017.06.012. Epub 2017 Jun 22. Review.

8.

Obesity-related, metabolic asthma: a new role for glucagon-like peptide 1 agonists.

Nguyen DV, Linderholm A, Haczku A, Kenyon N.

Lancet Respir Med. 2017 Mar;5(3):162-164. doi: 10.1016/S2213-2600(17)30051-6. Review. No abstract available.

PMID:
28266322
9.

Paradigms in chronic obstructive pulmonary disease: phenotypes, immunobiology, and therapy with a focus on vascular disease.

Schivo M, Albertson TE, Haczku A, Kenyon NJ, Zeki AA, Kuhn BT, Louie S, Avdalovic MV.

J Investig Med. 2017 Aug;65(6):953-963. doi: 10.1136/jim-2016-000358. Epub 2017 Mar 3. Review.

10.

Cutting Edge: Notch Signaling Promotes the Plasticity of Group-2 Innate Lymphoid Cells.

Zhang K, Xu X, Pasha MA, Siebel CW, Costello A, Haczku A, MacNamara K, Liang T, Zhu J, Bhandoola A, Maillard I, Yang Q.

J Immunol. 2017 Mar 1;198(5):1798-1803. doi: 10.4049/jimmunol.1601421. Epub 2017 Jan 23.

11.

The Th2 gene cluster unraveled: role of RHS6.

Flayer CH, Haczku A.

Allergy. 2017 May;72(5):679-681. doi: 10.1111/all.13130. No abstract available.

12.

Targeting IκBNS in allergic asthma: where it resides, matters.

Sengupta S, Haczku A.

Allergy. 2017 Jul;72(7):1003-1005. doi: 10.1111/all.13126. No abstract available.

13.

mTORC2 regulates multiple aspects of NKT-cell development and function.

Sklarz T, Guan P, Gohil M, Cotton RM, Ge MQ, Haczku A, Das R, Jordan MS.

Eur J Immunol. 2017 Mar;47(3):516-526. doi: 10.1002/eji.201646343. Epub 2017 Jan 27.

14.

Blomia tropicalis-Specific TCR Transgenic Th2 Cells Induce Inducible BALT and Severe Asthma in Mice by an IL-4/IL-13-Dependent Mechanism.

Chua YL, Liong KH, Huang CH, Wong HS, Zhou Q, Ler SS, Tang Y, Low CP, Koh HY, Kuo IC, Zhang Y, Wong WS, Peh HY, Lim HY, Ge MQ, Haczku A, Angeli V, MacAry PA, Chua KY, Kemeny DM.

J Immunol. 2016 Nov 15;197(10):3771-3781. Epub 2016 Oct 12.

15.

Patching it together: epicutaneous vaccination with heat-labile Escherichia coli toxin against birch pollen allergy.

Killingbeck SS, Ge MQ, Haczku A.

Allergy. 2017 Jan;72(1):5-8. doi: 10.1111/all.13064. No abstract available.

16.

Correction: Cutting Edge: Role of NK Cells and Surfactant Protein D in Dendritic Cell Lymph Node Homing: Effects of Ozone Exposure.

Ge MQ, Kokalari B, Flayer CH, Killingbeck SS, Redai IG, MacFarlane AW 4th, Hwang JW, Kolupoti A, Kemeny DM, Campbell KS, Haczku A.

J Immunol. 2016 Apr 1;196(7):3212. doi: 10.4049/jimmunol.1600095. No abstract available.

17.

Cutting Edge: Role of NK Cells and Surfactant Protein D in Dendritic Cell Lymph Node Homing: Effects of Ozone Exposure.

Ge MQ, Kokalari B, Flayer CH, Killingbeck SS, Redai IG, MacFarlane AW 4th, Hwang JW, Kolupoti A, Kemeny MD, Campbell KS, Haczku A.

J Immunol. 2016 Jan 15;196(2):553-7. doi: 10.4049/jimmunol.1403042. Epub 2015 Dec 16. Erratum in: J Immunol. 2016 Apr 1;196(7):3212.

18.

Group 2 innate lymphoid cells mediate ozone-induced airway inflammation and hyperresponsiveness in mice.

Yang Q, Ge MQ, Kokalari B, Redai IG, Wang X, Kemeny DM, Bhandoola A, Haczku A.

J Allergy Clin Immunol. 2016 Feb;137(2):571-8. doi: 10.1016/j.jaci.2015.06.037. Epub 2015 Aug 15.

19.

Properdin Contributes to Allergic Airway Inflammation through Local C3a Generation.

Wang Y, Miwa T, Ducka-Kokalari B, Redai IG, Sato S, Gullipalli D, Zangrilli JG, Haczku A, Song WC.

J Immunol. 2015 Aug 1;195(3):1171-81. doi: 10.4049/jimmunol.1401819. Epub 2015 Jun 26.

20.

Resistin-like molecule-β (RELM-β) targets airways fibroblasts to effect remodelling in asthma: from mouse to man.

Fang CL, Yin LJ, Sharma S, Kierstein S, Wu HF, Eid G, Haczku A, Corrigan CJ, Ying S.

Clin Exp Allergy. 2015 May;45(5):940-952. doi: 10.1111/cea.12481.

21.

Adeno-associated virus 9-mediated airway expression of antibody protects old and immunodeficient mice against influenza virus.

Adam VS, Crosariol M, Kumar S, Ge MQ, Czack SE, Roy S, Haczku A, Tretiakova A, Wilson JM, Limberis MP.

Clin Vaccine Immunol. 2014 Nov;21(11):1528-33. doi: 10.1128/CVI.00572-14. Epub 2014 Sep 10.

22.

In vivo evaluation of adeno-associated virus gene transfer in airways of mice with acute or chronic respiratory infection.

Myint M, Limberis MP, Bell P, Somanathan S, Haczku A, Wilson JM, Diamond SL.

Hum Gene Ther. 2014 Nov;25(11):966-76. doi: 10.1089/hum.2014.002. Epub 2014 Sep 22.

23.

Deficiency of melanoma differentiation-associated protein 5 results in exacerbated chronic postviral lung inflammation.

Kim WK, Jain D, Sánchez MD, Koziol-White CJ, Matthews K, Ge MQ, Haczku A, Panettieri RA Jr, Frieman MB, López CB.

Am J Respir Crit Care Med. 2014 Feb 15;189(4):437-48. doi: 10.1164/rccm.201307-1338OC.

24.

T cell factor 1 is required for group 2 innate lymphoid cell generation.

Yang Q, Monticelli LA, Saenz SA, Chi AW, Sonnenberg GF, Tang J, De Obaldia ME, Bailis W, Bryson JL, Toscano K, Huang J, Haczku A, Pear WS, Artis D, Bhandoola A.

Immunity. 2013 Apr 18;38(4):694-704. doi: 10.1016/j.immuni.2012.12.003.

25.

Autoreactive bronchus-associated lymphoid tissue in interstitial lung disease: friend or foe?

Jordan M, Haczku A.

Am J Respir Cell Mol Biol. 2013 Apr;48(4):397-8. No abstract available.

PMID:
23544886
26.

The effect of lipoprotein-associated phospholipase A2 deficiency on pulmonary allergic responses in Aspergillus fumigatus sensitized mice.

Jiang Z, Fehrenbach ML, Ravaioli G, Kokalari B, Redai IG, Sheardown SA, Wilson S, Macphee C, Haczku A.

Respir Res. 2012 Nov 12;13:100. doi: 10.1186/1465-9921-13-100.

27.

Prevention of alveolar destruction and airspace enlargement in a mouse model of pulmonary lymphangioleiomyomatosis (LAM).

Goncharova EA, Goncharov DA, Fehrenbach M, Khavin I, Ducka B, Hino O, Colby TV, Merrilees MJ, Haczku A, Albelda SM, Krymskaya VP.

Sci Transl Med. 2012 Oct 3;4(154):154ra134. doi: 10.1126/scitranslmed.3003840.

28.

The dendritic cell niche in chronic obstructive pulmonary disease.

Haczku A.

Respir Res. 2012 Sep 19;13:80. doi: 10.1186/1465-9921-13-80.

29.

Galectin-9: a suppressor of food allergy?

Sziksz E, Vannay A, Haczku A.

Allergy. 2012 Mar;67(3):293-5. doi: 10.1111/j.1398-9995.2011.02774.x. No abstract available.

30.

The B-cell superantigen Finegoldia magna protein L causes pulmonary inflammation by a mechanism dependent on MyD88 but not B cells or immunoglobulins.

Anderson AL, Zheng Y, Song D, Larosa D, Van Rooijen N, Kierstein G, Kierstein S, Haczku A, Levinson AI.

Inflamm Res. 2012 Feb;61(2):161-9. doi: 10.1007/s00011-012-0436-8. Epub 2012 Jan 17.

31.

Systemic FasL neutralization increases eosinophilic inflammation in a mouse model of asthma.

Sharma SK, Almeida FA, Kierstein S, Hortobagyi L, Lin T, Larkin A, Peterson J, Yagita H, Zangrilli JG, Haczku A.

Allergy. 2012 Mar;67(3):328-35. doi: 10.1111/j.1398-9995.2011.02763.x. Epub 2011 Dec 17.

32.

PARP-1: a new player in the asthma field?

Szabó É, Kovács I, Grune T, Haczku A, Virág L.

Allergy. 2011 Jul;66(7):811-4. doi: 10.1111/j.1398-9995.2011.02551.x. Epub 2011 Feb 2. No abstract available.

PMID:
21284655
33.

SP-D and regulation of the pulmonary innate immune system in allergic airway changes.

Forbes LR, Haczku A.

Clin Exp Allergy. 2010 Apr;40(4):547-62. doi: 10.1111/j.1365-2222.2010.03483.x. Review.

PMID:
20447075
34.

Recent advances in alveolar biology: evolution and function of alveolar proteins.

Orgeig S, Hiemstra PS, Veldhuizen EJ, Casals C, Clark HW, Haczku A, Knudsen L, Possmayer F.

Respir Physiol Neurobiol. 2010 Aug 31;173 Suppl:S43-54. doi: 10.1016/j.resp.2010.04.023. Epub 2010 Apr 28. Review.

35.

Deletion of microsomal prostaglandin E synthase-1 does not alter ozone-induced airway hyper-responsiveness.

Wang M, Cooper PR, Jiang M, Zhao H, Hui Y, Yao Y, Tate JC, Damera G, Lawson JA, Jester WF Jr, Haczku A, Panettieri RA Jr, FitzGerald GA.

J Pharmacol Exp Ther. 2010 Jul;334(1):63-8. doi: 10.1124/jpet.110.166678. Epub 2010 Apr 6.

36.

Inhibition of myristoylated alanine-rich C kinase substrate (MARCKS) protein inhibits ozone-induced airway neutrophilia and inflammation.

Damera G, Jester WF, Jiang M, Zhao H, Fogle HW, Mittelman M, Haczku A, Murphy E, Parikh I, Panettieri RA Jr.

Exp Lung Res. 2010 Mar;36(2):75-84. doi: 10.3109/01902140903131200. Erratum in: Exp Lung Res. 2010 Jun;36(5):321.

37.

Social stress and asthma: the role of corticosteroid insensitivity.

Haczku A, Panettieri RA Jr.

J Allergy Clin Immunol. 2010 Mar;125(3):550-8. doi: 10.1016/j.jaci.2009.11.005. Epub 2010 Feb 11. Review.

38.

Role of pathogenic oral flora in postoperative pneumonia following brain surgery.

Bágyi K, Haczku A, Márton I, Szabó J, Gáspár A, Andrási M, Varga I, Tóth J, Klekner A.

BMC Infect Dis. 2009 Jun 29;9:104. doi: 10.1186/1471-2334-9-104.

39.

Social stress enhances allergen-induced airway inflammation in mice and inhibits corticosteroid responsiveness of cytokine production.

Bailey MT, Kierstein S, Sharma S, Spaits M, Kinsey SG, Tliba O, Amrani Y, Sheridan JF, Panettieri RA, Haczku A.

J Immunol. 2009 Jun 15;182(12):7888-96. doi: 10.4049/jimmunol.0800891. Erratum in: J Immunol. 2009 Sep 1;183(5):3551. Amrani, Yassine [added].

40.

Protective role of the lung collectins surfactant protein A and surfactant protein D in airway inflammation.

Haczku A.

J Allergy Clin Immunol. 2008 Nov;122(5):861-79; quiz 880-1. doi: 10.1016/j.jaci.2008.10.014.

41.

Fluticasone propionate protects against ozone-induced airway inflammation and modified immune cell activation markers in healthy volunteers.

Alexis NE, Lay JC, Haczku A, Gong H, Linn W, Hazucha MJ, Harris B, Tal-Singer R, Peden DB.

Environ Health Perspect. 2008 Jun;116(6):799-805. doi: 10.1289/ehp.10981.

42.

Surfactant protein D inhibits TNF-alpha production by macrophages and dendritic cells in mice.

Hortobágyi L, Kierstein S, Krytska K, Zhu X, Das AM, Poulain F, Haczku A.

J Allergy Clin Immunol. 2008 Sep;122(3):521-528. doi: 10.1016/j.jaci.2008.05.002. Epub 2008 Jun 12.

43.

Essential role of IFNbeta and CD38 in TNFalpha-induced airway smooth muscle hyper-responsiveness.

Jain D, Keslacy S, Tliba O, Cao Y, Kierstein S, Amin K, Panettieri RA Jr, Haczku A, Amrani Y.

Immunobiology. 2008;213(6):499-509. doi: 10.1016/j.imbio.2007.12.002. Epub 2008 Jan 29.

44.

Ozone inhalation induces exacerbation of eosinophilic airway inflammation and hyperresponsiveness in allergen-sensitized mice.

Kierstein S, Krytska K, Sharma S, Amrani Y, Salmon M, Panettieri RA Jr, Zangrilli J, Haczku A.

Allergy. 2008 Apr;63(4):438-46. doi: 10.1111/j.1398-9995.2007.01587.x.

PMID:
18315731
45.

Chronic obstructive pulmonary disease and inhaled steroids alter surfactant protein D (SP-D) levels: a cross-sectional study.

Sims MW, Tal-Singer RM, Kierstein S, Musani AI, Beers MF, Panettieri RA, Haczku A.

Respir Res. 2008 Jan 28;9:13. doi: 10.1186/1465-9921-9-13.

46.

Absence of bacterially induced RELMbeta reduces injury in the dextran sodium sulfate model of colitis.

McVay LD, Keilbaugh SA, Wong TM, Kierstein S, Shin ME, Lehrke M, Lefterova MI, Shifflett DE, Barnes SL, Cominelli F, Cohn SM, Hecht G, Lazar MA, Haczku A, Wu GD.

J Clin Invest. 2006 Nov;116(11):2914-23. Epub 2006 Oct 5.

47.

Susceptibility to ozone-induced airway inflammation is associated with decreased levels of surfactant protein D.

Kierstein S, Poulain FR, Cao Y, Grous M, Mathias R, Kierstein G, Beers MF, Salmon M, Panettieri RA Jr, Haczku A.

Respir Res. 2006 Jun 1;7:85.

48.

IL-4 and IL-13 form a negative feedback circuit with surfactant protein-D in the allergic airway response.

Haczku A, Cao Y, Vass G, Kierstein S, Nath P, Atochina-Vasserman EN, Scanlon ST, Li L, Griswold DE, Chung KF, Poulain FR, Hawgood S, Beers MF, Crouch EC.

J Immunol. 2006 Mar 15;176(6):3557-65.

49.

Hyperpolarized 3He MRI in asthma measurements of regional ventilation following allergic sensitization and challenge in mice--preliminary results.

Haczku A, Emami K, Fischer MC, Kadlecek S, Ishii M, Panettieri RA, Rizi RR.

Acad Radiol. 2005 Nov;12(11):1362-70.

PMID:
16253848
50.

Role and regulation of lung collectins in allergic airway sensitization.

Haczku A.

Pharmacol Ther. 2006 Apr;110(1):14-34. Epub 2005 Oct 13. Review.

PMID:
16226313

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