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Items: 1 to 50 of 92

1.

Development of 5-Aminopyrazole-4-carboxamide-based Bumped-Kinase Inhibitors for Cryptosporidiosis Therapy.

Huang W, Hulverson MA, Choi R, Arnold SLM, Zhang Z, McCloskey MC, Whitman GR, Hackman RC, Rivas KL, Barrett LK, Ojo KK, Van Voorhis WC, Fan E.

J Med Chem. 2019 Mar 15. doi: 10.1021/acs.jmedchem.9b00069. [Epub ahead of print]

PMID:
30830766
2.

Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis.

Hulverson MA, Choi R, Arnold SLM, Schaefer DA, Hemphill A, McCloskey MC, Betzer DP, Müller J, Vidadala RSR, Whitman GR, Rivas KL, Barrett LK, Hackman RC, Love MS, McNamara CW, Shaughnessy TK, Kondratiuk A, Kurnick M, Banfor PN, Lynch JJ, Freiberg GM, Kempf DJ, Maly DJ, Riggs MW, Ojo KK, Van Voorhis WC.

Int J Parasitol. 2017 Oct;47(12):753-763. doi: 10.1016/j.ijpara.2017.08.006. Epub 2017 Sep 9.

3.

Human rhinovirus detection in the lower respiratory tract of hematopoietic cell transplant recipients: association with mortality.

Seo S, Waghmare A, Scott EM, Xie H, Kuypers JM, Hackman RC, Campbell AP, Choi SM, Leisenring WM, Jerome KR, Englund JA, Boeckh M.

Haematologica. 2017 Jun;102(6):1120-1130. doi: 10.3324/haematol.2016.153767. Epub 2017 Feb 9.

4.

Idiopathic pneumonia syndrome after hematopoietic cell transplantation: evidence of occult infectious etiologies.

Seo S, Renaud C, Kuypers JM, Chiu CY, Huang ML, Samayoa E, Xie H, Yu G, Fisher CE, Gooley TA, Miller S, Hackman RC, Myerson D, Sedlak RH, Kim YJ, Fukuda T, Fredricks DN, Madtes DK, Jerome KR, Boeckh M.

Blood. 2015 Jun 11;125(24):3789-97. doi: 10.1182/blood-2014-12-617035. Epub 2015 Apr 27.

5.

Langerhans cell homeostasis and turnover after nonmyeloablative and myeloablative allogeneic hematopoietic cell transplantation.

Mielcarek M, Kirkorian AY, Hackman RC, Price J, Storer BE, Wood BL, Leboeuf M, Bogunovic M, Storb R, Inamoto Y, Flowers ME, Martin PJ, Collin M, Merad M.

Transplantation. 2014 Sep 15;98(5):563-8. doi: 10.1097/TP.0000000000000097.

6.

Blood and gastric FOXP3+ T cells are not decreased in human gastric graft-versus-host disease.

Lord JD, Hackman RC, Gooley TA, Wood BL, Moklebust AC, Hockenbery DM, Steinbach G, Ziegler SF, McDonald GB.

Biol Blood Marrow Transplant. 2011 Apr;17(4):486-96. doi: 10.1016/j.bbmt.2010.09.015. Epub 2010 Sep 24.

7.

Safety and immunologic effects of IL-15 administration in nonhuman primates.

Berger C, Berger M, Hackman RC, Gough M, Elliott C, Jensen MC, Riddell SR.

Blood. 2009 Sep 17;114(12):2417-26. doi: 10.1182/blood-2008-12-189266. Epub 2009 Jul 15.

8.

Refractory colitis following anti-CTLA4 antibody therapy: analysis of mucosal FOXP3+ T cells.

Lord JD, Hackman RC, Moklebust A, Thompson JA, Higano CS, Chielens D, Steinbach G, McDonald GB.

Dig Dis Sci. 2010 May;55(5):1396-405. doi: 10.1007/s10620-009-0839-8. Epub 2009 Jun 9.

9.

Immunomodulatory effects of mixed hematopoietic chimerism: immune tolerance in canine model of lung transplantation.

Nash RA, Yunosov M, Abrams K, Hwang B, Castilla-Llorente C, Chen P, Farivar AS, Georges GE, Hackman RC, Lamm WJ, Lesnikova M, Ochs HD, Randolph-Habecker J, Ziegler SF, Storb R, Storer B, Madtes DK, Glenny R, Mulligan MS.

Am J Transplant. 2009 May;9(5):1037-47. doi: 10.1111/j.1600-6143.2009.02619.x. Erratum in: Am J Transplant. 2009 Jun;9(6):1486.

10.

Adenoviral graft-nephritis: case report and review of the literature.

Hensley JL, Sifri CD, Cathro HP, Lobo P, Sawyer RG, Brayman KL, Hackman RC, Pruett TL, Bonatti HJ.

Transpl Int. 2009 Jun;22(6):672-7. doi: 10.1111/j.1432-2277.2009.00838.x. Epub 2009 Feb 6. Review. No abstract available.

11.

Development and optimization of quantitative PCR for the diagnosis of invasive aspergillosis with bronchoalveolar lavage fluid.

Khot PD, Ko DL, Hackman RC, Fredricks DN.

BMC Infect Dis. 2008 May 29;8:73. doi: 10.1186/1471-2334-8-73.

12.

Tissue inhibitor of metalloproteinase-1 moderates airway re-epithelialization by regulating matrilysin activity.

Chen P, McGuire JK, Hackman RC, Kim KH, Black RA, Poindexter K, Yan W, Liu P, Chen AJ, Parks WC, Madtes DK.

Am J Pathol. 2008 May;172(5):1256-70. doi: 10.2353/ajpath.2008.070891. Epub 2008 Apr 1.

13.

MyD88 signaling contributes to early pulmonary responses to Aspergillus fumigatus.

Bretz C, Gersuk G, Knoblaugh S, Chaudhary N, Randolph-Habecker J, Hackman RC, Staab J, Marr KA.

Infect Immun. 2008 Mar;76(3):952-8. Epub 2007 Nov 26.

14.

Quantitative real-time polymerase chain reaction for detection of adenovirus after T cell-replete hematopoietic cell transplantation: viral load as a marker for invasive disease.

Erard V, Huang ML, Ferrenberg J, Nguy L, Stevens-Ayers TL, Hackman RC, Corey L, Boeckh M.

Clin Infect Dis. 2007 Oct 15;45(8):958-65. Epub 2007 Sep 6.

PMID:
17879908
15.

Tumor paint: a chlorotoxin:Cy5.5 bioconjugate for intraoperative visualization of cancer foci.

Veiseh M, Gabikian P, Bahrami SB, Veiseh O, Zhang M, Hackman RC, Ravanpay AC, Stroud MR, Kusuma Y, Hansen SJ, Kwok D, Munoz NM, Sze RW, Grady WM, Greenberg NM, Ellenbogen RG, Olson JM.

Cancer Res. 2007 Jul 15;67(14):6882-8.

16.

Respiratory virus infection among hematopoietic cell transplant recipients: evidence for asymptomatic parainfluenza virus infection.

Peck AJ, Englund JA, Kuypers J, Guthrie KA, Corey L, Morrow R, Hackman RC, Cent A, Boeckh M.

Blood. 2007 Sep 1;110(5):1681-8. Epub 2007 May 14.

17.

Training mouse pathologists: five years of pathology of mouse models of human disease workshops.

Sundberg JP, Hackman RC, HogenEsch H, Nikitin AY, Ward JM.

Toxicol Pathol. 2007 Apr;35(3):447-8. No abstract available.

PMID:
17474065
18.

Marrow fibrosis as a risk factor for posttransplantation outcome in patients with advanced myelodysplastic syndrome or acute myeloid leukemia with multilineage dysplasia.

Scott BL, Storer BE, Greene JE, Hackman RC, Appelbaum FR, Deeg HJ.

Biol Blood Marrow Transplant. 2007 Mar;13(3):345-54.

20.

Brief communication: fatal human metapneumovirus infection in stem-cell transplant recipients.

Englund JA, Boeckh M, Kuypers J, Nichols WG, Hackman RC, Morrow RA, Fredricks DN, Corey L.

Ann Intern Med. 2006 Mar 7;144(5):344-9.

PMID:
16520475
21.

Phenotypic analysis of mice lacking the Tmprss2-encoded protease.

Kim TS, Heinlein C, Hackman RC, Nelson PS.

Mol Cell Biol. 2006 Feb;26(3):965-75.

22.

Induction of apoptosis using inhibitors of lysophosphatidic acid acyltransferase-beta and anti-CD20 monoclonal antibodies for treatment of human non-Hodgkin's lymphomas.

Pagel JM, Laugen C, Bonham L, Hackman RC, Hockenbery DM, Bhatt R, Hollenback D, Carew H, Singer JW, Press OW.

Clin Cancer Res. 2005 Jul 1;11(13):4857-66.

23.

Toxicity and efficacy of daily dapsone as Pneumocystis jiroveci prophylaxis after hematopoietic stem cell transplantation: a case-control study.

Sangiolo D, Storer B, Nash R, Corey L, Davis C, Flowers M, Hackman RC, Boeckh M.

Biol Blood Marrow Transplant. 2005 Jul;11(7):521-9.

24.

Tissue inhibitor of metalloproteinase-1 deficiency amplifies acute lung injury in bleomycin-exposed mice.

Kim KH, Burkhart K, Chen P, Frevert CW, Randolph-Habecker J, Hackman RC, Soloway PD, Madtes DK.

Am J Respir Cell Mol Biol. 2005 Sep;33(3):271-9. Epub 2005 Jun 9.

25.

Developing a comprehensive mouse pathology program.

Sundberg JP, Haschek WM, Hackman RC, HogenEsch H.

Comp Med. 2004 Dec;54(6):617-21. No abstract available.

PMID:
15679258
26.

Adenovirus nephritis in hematopoietic stem-cell transplantation.

Bruno B, Zager RA, Boeckh MJ, Gooley TA, Myerson DH, Huang ML, Hackman RC.

Transplantation. 2004 Apr 15;77(7):1049-57.

PMID:
15087771
27.

Successful medical treatment of intestinal ulceration caused by Rhizopus microsporus.

Pinto-Marques P, Hockenbery DM, Hackman RC, Tapper D, McDonald GB.

Bone Marrow Transplant. 2003 Oct;32(7):739-40. No abstract available.

PMID:
13130324
28.

Association between acute and chronic graft-versus-host disease and bronchiolitis obliterans organizing pneumonia in recipients of hematopoietic stem cell transplants.

Freudenberger TD, Madtes DK, Curtis JR, Cummings P, Storer BE, Hackman RC.

Blood. 2003 Nov 15;102(10):3822-8. Epub 2003 Jul 17.

29.

Risks and outcomes of idiopathic pneumonia syndrome after nonmyeloablative and conventional conditioning regimens for allogeneic hematopoietic stem cell transplantation.

Fukuda T, Hackman RC, Guthrie KA, Sandmaier BM, Boeckh M, Maris MB, Maloney DG, Deeg HJ, Martin PJ, Storb RF, Madtes DK.

Blood. 2003 Oct 15;102(8):2777-85. Epub 2003 Jul 10.

30.

Adenovirus infection in hematopoietic stem cell transplantation: effect of ganciclovir and impact on survival.

Bruno B, Gooley T, Hackman RC, Davis C, Corey L, Boeckh M.

Biol Blood Marrow Transplant. 2003 May;9(5):341-52.

31.

Phase II trial of intravenous CI-1042 in patients with metastatic colorectal cancer.

Hamid O, Varterasian ML, Wadler S, Hecht JR, Benson A 3rd, Galanis E, Uprichard M, Omer C, Bycott P, Hackman RC, Shields AF.

J Clin Oncol. 2003 Apr 15;21(8):1498-504.

PMID:
12697873
32.

Contribution of transplanted bone marrow cells to Purkinje neurons in human adult brains.

Weimann JM, Charlton CA, Brazelton TR, Hackman RC, Blau HM.

Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):2088-93. Epub 2003 Feb 7.

33.

Interleukin-7 improves CD4 T-cell reconstitution after autologous CD34 cell transplantation in monkeys.

Storek J, Gillespy T 3rd, Lu H, Joseph A, Dawson MA, Gough M, Morris J, Hackman RC, Horn PA, Sale GE, Andrews RG, Maloney DG, Kiem HP.

Blood. 2003 May 15;101(10):4209-18. Epub 2003 Jan 23.

34.

Adherence of adoptively transferred alloreactive Th1 cells in lung: partial dependence on LFA-1 and ICAM-1.

Dixon AE, Mandac JB, Martin PJ, Hackman RC, Madtes DK, Clark JG.

Am J Physiol Lung Cell Mol Physiol. 2000 Sep;279(3):L583-91.

35.

Neutralization of tumor necrosis factor-alpha action delays but does not prevent lung injury induced by alloreactive T helper 1 cells.

Clark JG, Mandac JB, Dixon AE, Martin PJ, Hackman RC, Madtes DK.

Transplantation. 2000 Jul 15;70(1):39-43.

PMID:
10919572
36.

Idiopathic pneumonia after bone marrow transplantation: cytokine activation and lipopolysaccharide amplification in the bronchoalveolar compartment.

Clark JG, Madtes DK, Martin TR, Hackman RC, Farrand AL, Crawford SW.

Crit Care Med. 1999 Sep;27(9):1800-6.

PMID:
10507601
37.

Alloreactive Th1 cells localize in lung and induce acute lung injury.

Dixon AE, Mandac JB, Martin PJ, Madtes DK, Hackman RC, Clark JG.

Chest. 1999 Jul;116(1 Suppl):36S-37S. No abstract available.

PMID:
10424585
38.

Endoscopic and histologic diagnosis of intestinal graft-versus-host disease after marrow transplantation.

Ponec RJ, Hackman RC, McDonald GB.

Gastrointest Endosc. 1999 May;49(5):612-21.

PMID:
10228260
39.

Transforming growth factor-alpha deficiency reduces pulmonary fibrosis in transgenic mice.

Madtes DK, Elston AL, Hackman RC, Dunn AR, Clark JG.

Am J Respir Cell Mol Biol. 1999 May;20(5):924-34.

PMID:
10226062
40.

The effect of prophylactic fluconazole on the clinical spectrum of fungal diseases in bone marrow transplant recipients with special attention to hepatic candidiasis. An autopsy study of 355 patients.

van Burik JH, Leisenring W, Myerson D, Hackman RC, Shulman HM, Sale GE, Bowden RA, McDonald GB.

Medicine (Baltimore). 1998 Jul;77(4):246-54.

41.
42.

Lymphocytic gastritis resembling graft-vs.-host disease following autologous hematopoietic cell transplantation.

Tzung SP, Hackman RC, Hockenbery DM, Bensinger W, Schiffman K, McDonald GB.

Biol Blood Marrow Transplant. 1998;4(1):43-8.

PMID:
9701391
43.

T cells specific for a polymorphic segment of CD45 induce graft-versus-host disease with predominant pulmonary vasculitis.

Chen W, Chatta GS, Rubin WD, Clark JG, Hackman RC, Madtes DK, Ligitt DH, Kusunoki Y, Martin PJ, Cheever MA.

J Immunol. 1998 Jul 15;161(2):909-18.

44.

Acute pancreatitis in marrow transplant patients: prevalence at autopsy and risk factor analysis.

Ko CW, Gooley T, Schoch HG, Myerson D, Hackman RC, Shulman HM, Sale GE, Lee SP, McDonald GB.

Bone Marrow Transplant. 1997 Dec;20(12):1081-6.

45.

Effect of recombinant canine stem cell factor, a c-kit ligand, on hematopoietic recovery after DLA-identical littermate marrow transplants in dogs.

Schuening FG, von Kalle C, Kiem HP, Appelbaum FR, Deeg HJ, Pepe M, Gooley T, Graham TC, Hackman RC, Storb R.

Exp Hematol. 1997 Nov;25(12):1240-5.

PMID:
9357967
46.
47.

Nocardiosis after bone marrow transplantation: a retrospective study.

van Burik JA, Hackman RC, Nadeem SQ, Hiemenz JW, White MH, Flowers ME, Bowden RA.

Clin Infect Dis. 1997 Jun;24(6):1154-60.

PMID:
9195074
48.

Idiopathic pneumonia syndrome: changing spectrum of lung injury after marrow transplantation.

Kantrow SP, Hackman RC, Boeckh M, Myerson D, Crawford SW.

Transplantation. 1997 Apr 27;63(8):1079-86.

PMID:
9133468
49.

Bleeding from gastric antral vascular ectasia in marrow transplant patients.

Tobin RW, Hackman RC, Kimmey MB, Durtschi MB, Hayashi A, Malik R, McDonald MF, McDonald GB.

Gastrointest Endosc. 1996 Sep;44(3):223-9.

PMID:
8885337
50.

Legionellosis in a bone marrow transplant center.

Harrington RD, Woolfrey AE, Bowden R, McDowell MG, Hackman RC.

Bone Marrow Transplant. 1996 Aug;18(2):361-8.

PMID:
8864447

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