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Items: 1 to 50 of 160

1.

Correction: Type 2 Diabetes Risk Allele Loci in the Qatari Population.

O'Beirne SL, Salit J, Rodriguez-Flores JL, Staudt MR, Abi Khalil C, Fakhro KA, Robay A, Ramstetter MD, Al-Azwani IK, Malek JA, Zirie M, Jayyousi A, Badii R, Al-Nabet Al-Marri A, Chiuchiolo MJ, Al-Shakaki A, Chidiac O, Gharbiah M, Bener A, Stadler D, Hackett NR, Mezey JG, Crystal RG.

PLoS One. 2016 Aug 23;11(8):e0161910. doi: 10.1371/journal.pone.0161910. eCollection 2016.

2.

Type 2 Diabetes Risk Allele Loci in the Qatari Population.

O'Beirne SL, Salit J, Rodriguez-Flores JL, Staudt MR, Abi Khalil C, Fakhro KA, Robay A, Ramstetter MD, Al-Azwani IK, Malek JA, Zirie M, Jayyousi A, Badii R, Al-Nabet Al-Marri A, Chiuchiolo MJ, Al-Shakaki A, Chidiac O, Gharbiah M, Bener A, Stadler D, Hackett NR, Mezey JG, Crystal RG.

PLoS One. 2016 Jul 6;11(7):e0156834. doi: 10.1371/journal.pone.0156834. eCollection 2016. Erratum in: PLoS One. 2016;11(8):e0161910.

3.

Performing dual roles in education and practice.

Hackett N, Harvey-Lloyd J, Rooke N.

Nurs Manag (Harrow). 2016 Jun;23(3):31-7. doi: 10.7748/nm.23.3.31.s28.

PMID:
27246433
4.

Assessing the safety of outpatient ventral hernia repair: a NSQIP analysis of 7666 patients.

Qin C, Hackett NJ, Kim JY.

Hernia. 2015 Dec;19(6):919-26. doi: 10.1007/s10029-015-1426-x. Epub 2015 Oct 27.

PMID:
26508500
5.

Transcriptional maturation of the mouse auditory forebrain.

Hackett TA, Guo Y, Clause A, Hackett NJ, Garbett K, Zhang P, Polley DB, Mirnics K.

BMC Genomics. 2015 Aug 14;16:606. doi: 10.1186/s12864-015-1709-8.

6.

Older Adults and Unanticipated Hospital Admission within 30 Days of Ambulatory Surgery: An Analysis of 53,667 Ambulatory Surgical Procedures.

De Oliveira GS Jr, Holl JL, Lindquist LA, Hackett NJ, Kim JY, McCarthy RJ.

J Am Geriatr Soc. 2015 Aug;63(8):1679-85. doi: 10.1111/jgs.13537. Epub 2015 Jul 22.

PMID:
26200608
7.

Differential maturation of vesicular glutamate and GABA transporter expression in the mouse auditory forebrain during the first weeks of hearing.

Hackett TA, Clause AR, Takahata T, Hackett NJ, Polley DB.

Brain Struct Funct. 2016 Jun;221(5):2619-73. doi: 10.1007/s00429-015-1062-3. Epub 2015 Jul 10.

8.

Surgical duration and risk of Urinary Tract Infection: An analysis of 1,452,369 patients using the National Surgical Quality Improvement Program (NSQIP).

Qin C, de Oliveira G, Hackett N, Kim JY.

Int J Surg. 2015 Aug;20:107-12. doi: 10.1016/j.ijsu.2015.05.051. Epub 2015 Jun 6.

9.

ASA class is a reliable independent predictor of medical complications and mortality following surgery.

Hackett NJ, De Oliveira GS, Jain UK, Kim JY.

Int J Surg. 2015 Jun;18:184-90. doi: 10.1016/j.ijsu.2015.04.079. Epub 2015 Apr 30.

10.

Oropharyngeal Contamination Predisposes to Complications after Neck Dissection: An Analysis of 9462 Patients.

Jain U, Somerville J, Saha S, Hackett NJ, Ver Halen JP, Antony AK, Samant S.

Otolaryngol Head Neck Surg. 2015 Jul;153(1):71-8. doi: 10.1177/0194599815581808. Epub 2015 Apr 27.

PMID:
25917665
11.

Genetic modification of neurons to express bevacizumab for local anti-angiogenesis treatment of glioblastoma.

Hicks MJ, Funato K, Wang L, Aronowitz E, Dyke JP, Ballon DJ, Havlicek DF, Frenk EZ, De BP, Chiuchiolo MJ, Sondhi D, Hackett NR, Kaminsky SM, Tabar V, Crystal RG.

Cancer Gene Ther. 2015 Jan;22(1):1-8. doi: 10.1038/cgt.2014.58. Epub 2014 Dec 12.

12.

Smoking accelerates aging of the small airway epithelium.

Walters MS, De BP, Salit J, Buro-Auriemma LJ, Wilson T, Rogalski AM, Lief L, Hackett NR, Staudt MR, Tilley AE, Harvey BG, Kaner RJ, Mezey JG, Ashbridge B, Moore MA, Crystal RG.

Respir Res. 2014 Sep 24;15:94. doi: 10.1186/s12931-014-0094-1.

13.

Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2.

Ryan DM, Vincent TL, Salit J, Walters MS, Agosto-Perez F, Shaykhiev R, Strulovici-Barel Y, Downey RJ, Buro-Auriemma LJ, Staudt MR, Hackett NR, Mezey JG, Crystal RG.

PLoS One. 2014 Feb 3;9(2):e88051. doi: 10.1371/journal.pone.0088051. eCollection 2014.

14.

Partial correction of the CNS lysosomal storage defect in a mouse model of juvenile neuronal ceroid lipofuscinosis by neonatal CNS administration of an adeno-associated virus serotype rh.10 vector expressing the human CLN3 gene.

Sondhi D, Scott EC, Chen A, Hackett NR, Wong AM, Kubiak A, Nelvagal HR, Pearse Y, Cotman SL, Cooper JD, Crystal RG.

Hum Gene Ther. 2014 Mar;25(3):223-39. doi: 10.1089/hum.2012.253. Epub 2014 Mar 4.

15.

HEFT: eQTL analysis of many thousands of expressed genes while simultaneously controlling for hidden factors.

Gao C, Tignor NL, Salit J, Strulovici-Barel Y, Hackett NR, Crystal RG, Mezey JG.

Bioinformatics. 2014 Feb 1;30(3):369-76. doi: 10.1093/bioinformatics/btt690. Epub 2013 Dec 4.

16.

Prevalence of the apolipoprotein E Arg145Cys dyslipidemia at-risk polymorphism in African-derived populations.

Abou Ziki MD, Strulovici-Barel Y, Hackett NR, Rodriguez-Flores JL, Mezey JG, Salit J, Radisch S, Hollmann C, Chouchane L, Malek J, Zirie MA, Jayyuosi A, Gotto AM Jr, Crystal RG.

Am J Cardiol. 2014 Jan 15;113(2):302-8. doi: 10.1016/j.amjcard.2013.09.021. Epub 2013 Oct 3.

17.

Intrapleural administration of an AAVrh.10 vector coding for human α1-antitrypsin for the treatment of α1-antitrypsin deficiency.

Chiuchiolo MJ, Kaminsky SM, Sondhi D, Hackett NR, Rosenberg JB, Frenk EZ, Hwang Y, Van de Graaf BG, Hutt JA, Wang G, Benson J, Crystal RG.

Hum Gene Ther Clin Dev. 2013 Dec;24(4):161-73. doi: 10.1089/humc.2013.168.

PMID:
24191907
18.

Exome sequencing identifies potential risk variants for Mendelian disorders at high prevalence in Qatar.

Rodriguez-Flores JL, Fakhro K, Hackett NR, Salit J, Fuller J, Agosto-Perez F, Gharbiah M, Malek JA, Zirie M, Jayyousi A, Badii R, Al-Nabet Al-Marri A, Chouchane L, Stadler DJ, Mezey JG, Crystal RG.

Hum Mutat. 2014 Jan;35(1):105-16. doi: 10.1002/humu.22460. Epub 2013 Nov 10.

19.

Spectrum of ocular manifestations in CLN2-associated batten (Jansky-Bielschowsky) disease correlate with advancing age and deteriorating neurological function.

Orlin A, Sondhi D, Witmer MT, Wessel MM, Mezey JG, Kaminsky SM, Hackett NR, Yohay K, Kosofsky B, Souweidane MM, Kaplitt MG, D'Amico DJ, Crystal RG, Kiss S.

PLoS One. 2013 Aug 28;8(8):e73128. doi: 10.1371/journal.pone.0073128. eCollection 2013.

20.

Airway basal cells of healthy smokers express an embryonic stem cell signature relevant to lung cancer.

Shaykhiev R, Wang R, Zwick RK, Hackett NR, Leung R, Moore MA, Sima CS, Chao IW, Downey RJ, Strulovici-Barel Y, Salit J, Crystal RG.

Stem Cells. 2013 Sep;31(9):1992-2002. doi: 10.1002/stem.1459.

21.

Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression.

Buro-Auriemma LJ, Salit J, Hackett NR, Walters MS, Strulovici-Barel Y, Staudt MR, Fuller J, Mahmoud M, Stevenson CS, Hilton H, Ho MW, Crystal RG.

Hum Mol Genet. 2013 Dec 1;22(23):4726-38. doi: 10.1093/hmg/ddt326. Epub 2013 Jul 10.

22.

RFX3 modulation of FOXJ1 regulation of cilia genes in the human airway epithelium.

Didon L, Zwick RK, Chao IW, Walters MS, Wang R, Hackett NR, Crystal RG.

Respir Res. 2013 Jul 3;14:70. doi: 10.1186/1465-9921-14-70.

23.

Safety of direct cardiac administration of AdVEGF-All6A+, a replication-deficient adenovirus vector cDNA/genomic hybrid expressing all three major isoforms of human vascular endothelial growth factor, to the ischemic myocardium of rats.

Kaminsky SM, Quach L, Chen S, Pierre-Destine L, Van de Graaf B, Monette S, Rosenberg JB, De BP, Sondhi D, Hackett NR, Mezey JG, Rosengart TK, Crystal RG.

Hum Gene Ther Clin Dev. 2013 Mar;24(1):38-46. doi: 10.1089/humc.2013.054.

PMID:
23692382
24.

RGD capsid modification enhances mucosal protective immunity of a non-human primate adenovirus vector expressing Pseudomonas aeruginosa OprF.

Krause A, Whu WZ, Qiu J, Wafadari D, Hackett NR, Sharma A, Crystal RG, Worgall S.

Clin Exp Immunol. 2013 Aug;173(2):230-41. doi: 10.1111/cei.12101.

25.

In vivo cardiac cellular reprogramming efficacy is enhanced by angiogenic preconditioning of the infarcted myocardium with vascular endothelial growth factor.

Mathison M, Gersch RP, Nasser A, Lilo S, Korman M, Fourman M, Hackett N, Shroyer K, Yang J, Ma Y, Crystal RG, Rosengart TK.

J Am Heart Assoc. 2012 Dec;1(6):e005652. doi: 10.1161/JAHA.112.005652. Epub 2012 Dec 19.

26.

A sensitive and specific diagnostic test for hearing loss using a microdroplet PCR-based approach and next generation sequencing.

Schrauwen I, Sommen M, Corneveaux JJ, Reiman RA, Hackett NJ, Claes C, Claes K, Bitner-Glindzicz M, Coucke P, Van Camp G, Huentelman MJ.

Am J Med Genet A. 2013 Jan;161A(1):145-52. doi: 10.1002/ajmg.a.35737. Epub 2012 Dec 3.

PMID:
23208854
27.

Exome sequencing of only seven Qataris identifies potentially deleterious variants in the Qatari population.

Rodriguez-Flores JL, Fuller J, Hackett NR, Salit J, Malek JA, Al-Dous E, Chouchane L, Zirie M, Jayoussi A, Mahmoud MA, Crystal RG, Mezey JG.

PLoS One. 2012;7(11):e47614. doi: 10.1371/journal.pone.0047614. Epub 2012 Nov 6.

28.

Long-term expression and safety of administration of AAVrh.10hCLN2 to the brain of rats and nonhuman primates for the treatment of late infantile neuronal ceroid lipofuscinosis.

Sondhi D, Johnson L, Purpura K, Monette S, Souweidane MM, Kaplitt MG, Kosofsky B, Yohay K, Ballon D, Dyke J, Kaminksy SM, Hackett NR, Crystal RG.

Hum Gene Ther Methods. 2012 Oct;23(5):324-35. doi: 10.1089/hgtb.2012.120. Epub 2012 Nov 6.

29.

Assessment of disease severity in late infantile neuronal ceroid lipofuscinosis using multiparametric MR imaging.

Dyke JP, Sondhi D, Voss HU, Shungu DC, Mao X, Yohay K, Worgall S, Hackett NR, Hollmann C, Yeotsas ME, Jeong AL, Van de Graaf B, Cao I, Kaminsky SM, Heier LA, Rudser KD, Souweidane MM, Kaplitt MG, Kosofsky B, Crystal RG, Ballon D.

AJNR Am J Neuroradiol. 2013 Apr;34(4):884-9. doi: 10.3174/ajnr.A3297. Epub 2012 Oct 4.

30.

AAV-directed persistent expression of a gene encoding anti-nicotine antibody for smoking cessation.

Hicks MJ, Rosenberg JB, De BP, Pagovich OE, Young CN, Qiu JP, Kaminsky SM, Hackett NR, Worgall S, Janda KD, Davisson RL, Crystal RG.

Sci Transl Med. 2012 Jun 27;4(140):140ra87. doi: 10.1126/scitranslmed.3003611.

31.

Inferring genome-wide patterns of admixture in Qataris using fifty-five ancestral populations.

Omberg L, Salit J, Hackett N, Fuller J, Matthew R, Chouchane L, Rodriguez-Flores JL, Bustamante C, Crystal RG, Mezey JG.

BMC Genet. 2012 Jun 26;13:49. doi: 10.1186/1471-2156-13-49.

32.

Empirical Bayes conditional independence graphs for regulatory network recovery.

Mahdi R, Madduri AS, Wang G, Strulovici-Barel Y, Salit J, Hackett NR, Crystal RG, Mezey JG.

Bioinformatics. 2012 Aug 1;28(15):2029-36. doi: 10.1093/bioinformatics/bts312. Epub 2012 Jun 8.

33.

Correction of brain oligodendrocytes by AAVrh.10 intracerebral gene therapy in metachromatic leukodystrophy mice.

Piguet F, Sondhi D, Piraud M, Fouquet F, Hackett NR, Ahouansou O, Vanier MT, Bieche I, Aubourg P, Crystal RG, Cartier N, Sevin C.

Hum Gene Ther. 2012 Aug;23(8):903-14. doi: 10.1089/hum.2012.015. Epub 2012 Jul 23.

34.

AAVrh.10-mediated expression of an anti-cocaine antibody mediates persistent passive immunization that suppresses cocaine-induced behavior.

Rosenberg JB, Hicks MJ, De BP, Pagovich O, Frenk E, Janda KD, Wee S, Koob GF, Hackett NR, Kaminsky SM, Worgall S, Tignor N, Mezey JG, Crystal RG.

Hum Gene Ther. 2012 May;23(5):451-9. doi: 10.1089/hum.2011.178.

35.

Double-blinded, placebo-controlled, randomized gene therapy using surgery for vector delivery.

Crystal RG, Kaminsky SM, Hackett NR, Rosengart TK.

Hum Gene Ther. 2012 May;23(5):438-41. doi: 10.1089/hum.2012.062. Epub 2012 Apr 23. No abstract available.

PMID:
22452798
36.

Airway basal cell vascular endothelial growth factor-mediated cross-talk regulates endothelial cell-dependent growth support of human airway basal cells.

Curradi G, Walters MS, Ding BS, Rafii S, Hackett NR, Crystal RG.

Cell Mol Life Sci. 2012 Jul;69(13):2217-31. doi: 10.1007/s00018-012-0922-8. Epub 2012 Mar 1.

37.

RNA-Seq quantification of the human small airway epithelium transcriptome.

Hackett NR, Butler MW, Shaykhiev R, Salit J, Omberg L, Rodriguez-Flores JL, Mezey JG, Strulovici-Barel Y, Wang G, Didon L, Crystal RG.

BMC Genomics. 2012 Feb 29;13:82. doi: 10.1186/1471-2164-13-82.

38.

Biologic phenotyping of the human small airway epithelial response to cigarette smoking.

Tilley AE, O'Connor TP, Hackett NR, Strulovici-Barel Y, Salit J, Amoroso N, Zhou XK, Raman T, Omberg L, Clark A, Mezey J, Crystal RG.

PLoS One. 2011;6(7):e22798. doi: 10.1371/journal.pone.0022798. Epub 2011 Jul 28.

39.

Persistent suppression of ocular neovascularization with intravitreal administration of AAVrh.10 coding for bevacizumab.

Mao Y, Kiss S, Boyer JL, Hackett NR, Qiu J, Carbone A, Mezey JG, Kaminsky SM, D'Amico DJ, Crystal RG.

Hum Gene Ther. 2011 Dec;22(12):1525-35. doi: 10.1089/hum.2011.090. Epub 2011 Oct 27.

40.

The human airway epithelial basal cell transcriptome.

Hackett NR, Shaykhiev R, Walters MS, Wang R, Zwick RK, Ferris B, Witover B, Salit J, Crystal RG.

PLoS One. 2011 May 4;6(5):e18378. doi: 10.1371/journal.pone.0018378.

41.

Down-regulation of the canonical Wnt β-catenin pathway in the airway epithelium of healthy smokers and smokers with COPD.

Wang R, Ahmed J, Wang G, Hassan I, Strulovici-Barel Y, Hackett NR, Crystal RG.

PLoS One. 2011 Apr 7;6(4):e14793. doi: 10.1371/journal.pone.0014793.

42.

Glutathione S-transferase copy number variation alters lung gene expression.

Butler MW, Hackett NR, Salit J, Strulovici-Barel Y, Omberg L, Mezey J, Crystal RG.

Eur Respir J. 2011 Jul;38(1):15-28. doi: 10.1183/09031936.00029210. Epub 2011 Feb 24.

43.

Modulation of cystatin A expression in human airway epithelium related to genotype, smoking, COPD, and lung cancer.

Butler MW, Fukui T, Salit J, Shaykhiev R, Mezey JG, Hackett NR, Crystal RG.

Cancer Res. 2011 Apr 1;71(7):2572-81. doi: 10.1158/0008-5472.CAN-10-2046. Epub 2011 Feb 16.

44.

Cocaine analog coupled to disrupted adenovirus: a vaccine strategy to evoke high-titer immunity against addictive drugs.

Hicks MJ, De BP, Rosenberg JB, Davidson JT, Moreno AY, Janda KD, Wee S, Koob GF, Hackett NR, Kaminsky SM, Worgall S, Toth M, Mezey JG, Crystal RG.

Mol Ther. 2011 Mar;19(3):612-9. doi: 10.1038/mt.2010.280. Epub 2011 Jan 4.

45.

Smoking-mediated up-regulation of GAD67 expression in the human airway epithelium.

Wang G, Wang R, Ferris B, Salit J, Strulovici-Barel Y, Hackett NR, Crystal RG.

Respir Res. 2010 Oct 29;11:150. doi: 10.1186/1465-9921-11-150.

46.

Smoking-induced upregulation of AKR1B10 expression in the airway epithelium of healthy individuals.

Wang R, Wang G, Ricard MJ, Ferris B, Strulovici-Barel Y, Salit J, Hackett NR, Gudas LJ, Crystal RG.

Chest. 2010 Dec;138(6):1402-10. doi: 10.1378/chest.09-2634. Epub 2010 Aug 12.

47.

Gene therapy for late infantile neuronal ceroid lipofuscinosis: neurosurgical considerations.

Souweidane MM, Fraser JF, Arkin LM, Sondhi D, Hackett NR, Kaminsky SM, Heier L, Kosofsky BE, Worgall S, Crystal RG, Kaplitt MG.

J Neurosurg Pediatr. 2010 Aug;6(2):115-22. doi: 10.3171/2010.4.PEDS09507.

48.

Population genetic structure of the people of Qatar.

Hunter-Zinck H, Musharoff S, Salit J, Al-Ali KA, Chouchane L, Gohar A, Matthews R, Butler MW, Fuller J, Hackett NR, Crystal RG, Clark AG.

Am J Hum Genet. 2010 Jul 9;87(1):17-25. doi: 10.1016/j.ajhg.2010.05.018. Epub 2010 Jun 24.

49.

Persistent expression of biologically active anti-HER2 antibody by AAVrh.10-mediated gene transfer.

Wang G, Qiu J, Wang R, Krause A, Boyer JL, Hackett NR, Crystal RG.

Cancer Gene Ther. 2010 Aug;17(8):559-70. doi: 10.1038/cgt.2010.11. Epub 2010 May 7.

50.

Protective immunity against a lethal respiratory Yersinia pestis challenge induced by V antigen or the F1 capsular antigen incorporated into adenovirus capsid.

Boyer JL, Sofer-Podesta C, Ang J, Hackett NR, Chiuchiolo MJ, Senina S, Perlin D, Crystal RG.

Hum Gene Ther. 2010 Jul;21(7):891-901. doi: 10.1089/hum.2009.148.

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