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Items: 49

1.

Complementary approaches to imaging sub-cellular lipid architectures in live bacteria using phosphorescent iridium complexes and Raman spectroscopy.

Ranieri AM, Caporale C, Fiorini V, Hubbard A, Rigby P, Stagni S, Watkin E, Ogden MI, Hackett MJ, Massi M.

Chemistry. 2019 Jun 13. doi: 10.1002/chem.201902023. [Epub ahead of print]

PMID:
31197892
2.

A Factorial Analysis of Drug and Bleeding Effects in Toxicokinetic Studies.

Hackett MJ, Kinderknecht K, Niemuth NA, Taylor JA, Gibbs S, Novak J, Harbo S.

Toxicol Sci. 2019 Apr 15. pii: kfz092. doi: 10.1093/toxsci/kfz092. [Epub ahead of print]

PMID:
30985877
3.

Secondary Structural Changes in Proteins as a Result of Electroadsorption at Aqueous-Organogel Interfaces.

Booth SG, Felisilda BMB, Alvarez de Eulate E, Gustafsson OJR, Arooj M, Mancera RL, Dryfe RAW, Hackett MJ, Arrigan DWM.

Langmuir. 2019 Apr 30;35(17):5821-5829. doi: 10.1021/acs.langmuir.8b04227. Epub 2019 Apr 18.

PMID:
30955327
4.

Synchrotron macro ATR-FTIR microspectroscopy for high-resolution chemical mapping of single cells.

Vongsvivut J, Pérez-Guaita D, Wood BR, Heraud P, Khambatta K, Hartnell D, Hackett MJ, Tobin MJ.

Analyst. 2019 May 13;144(10):3226-3238. doi: 10.1039/c8an01543k.

PMID:
30869675
5.

Multimodal Imaging Analyses of Brain Hippocampal Formation Reveal Reduced Cu and Lipid Content and Increased Lactate Content in Non-Insulin-Dependent Diabetic Mice.

Hackett MJ, Hollings A, Majimbi M, Brook E, Cochran B, Giles C, Lam V, Nesbit M, Rye KA, Mamo JCL, Takechi R.

ACS Chem Neurosci. 2019 May 15;10(5):2533-2540. doi: 10.1021/acschemneuro.9b00039. Epub 2019 Mar 20.

PMID:
30855947
6.

A comparison of parametric and integrative approaches for X-ray fluorescence analysis applied to a Stroke model.

Crawford AM, Sylvain NJ, Hou H, Hackett MJ, Pushie MJ, Pickering IJ, George GN, Kelly ME.

J Synchrotron Radiat. 2018 Nov 1;25(Pt 6):1780-1789. doi: 10.1107/S1600577518010895. Epub 2018 Oct 8.

PMID:
30407190
7.

Elemental characterisation of the pyramidal neuron layer within the rat and mouse hippocampus.

Hackett MJ, Hollings A, Caine S, Bewer BE, Alaverdashvili M, Takechi R, Mamo JCL, Jones MWM, de Jonge MD, Paterson PG, Pickering IJ, George GN.

Metallomics. 2019 Jan 23;11(1):151-165. doi: 10.1039/c8mt00230d.

PMID:
30398510
8.

Longitudinal Performance of Senescence Accelerated Mouse Prone-Strain 8 (SAMP8) Mice in an Olfactory-Visual Water Maze Challenge.

Lam V, Takechi R, Albrecht MA, D'Alonzo ZJ, Graneri L, Hackett MJ, Coulson S, Fimognari N, Nesbit M, Mamo JCL.

Front Behav Neurosci. 2018 Aug 28;12:174. doi: 10.3389/fnbeh.2018.00174. eCollection 2018.

9.

Direct label-free imaging of brain tissue using synchrotron light: a review of new spectroscopic tools for the modern neuroscientist.

Pushie MJ, Kelly ME, Hackett MJ.

Analyst. 2018 Aug 6;143(16):3761-3774. doi: 10.1039/c7an01904a. Review.

PMID:
29961790
10.

Revealing the spatial distribution of chemical species within latent fingermarks using vibrational spectroscopy.

Dorakumbura BN, Boseley RE, Becker T, Martin DE, Richter A, Tobin MJ, van Bronswjik W, Vongsvivut J, Hackett MJ, Lewis SW.

Analyst. 2018 Aug 20;143(17):4027-4039. doi: 10.1039/c7an01615h.

PMID:
29956693
11.

Biospectroscopic Imaging Provides Evidence of Hippocampal Zn Deficiency and Decreased Lipid Unsaturation in an Accelerated Aging Mouse Model.

Fimognari N, Hollings A, Lam V, Tidy RJ, Kewish CM, Albrecht MA, Takechi R, Mamo JCL, Hackett MJ.

ACS Chem Neurosci. 2018 Nov 21;9(11):2774-2785. doi: 10.1021/acschemneuro.8b00193. Epub 2018 Jul 9.

PMID:
29901988
12.

Protein-Energy Malnutrition Exacerbates Stroke-Induced Forelimb Abnormalities and Dampens Neuroinflammation.

Alaverdashvili M, Caine S, Li X, Hackett MJ, Bradley MP, Nichol H, Paterson PG.

Transl Stroke Res. 2018 Dec;9(6):622-630. doi: 10.1007/s12975-018-0613-3. Epub 2018 Feb 3.

PMID:
29397529
13.

Revealing the Penumbra through Imaging Elemental Markers of Cellular Metabolism in an Ischemic Stroke Model.

Pushie MJ, Crawford AM, Sylvain NJ, Hou H, Hackett MJ, George GN, Kelly ME.

ACS Chem Neurosci. 2018 May 16;9(5):886-893. doi: 10.1021/acschemneuro.7b00382. Epub 2018 Jan 30.

PMID:
29370523
14.

Iron oxide nanoclusters for T 1 magnetic resonance imaging of non-human primates.

Lu Y, Xu YJ, Zhang GB, Ling D, Wang MQ, Zhou Y, Wu YD, Wu T, Hackett MJ, Hyo Kim B, Chang H, Kim J, Hu XT, Dong L, Lee N, Li F, He JC, Zhang L, Wen HQ, Yang B, Hong Choi S, Hyeon T, Zou DH.

Nat Biomed Eng. 2017 Aug;1(8):637-643. doi: 10.1038/s41551-017-0116-7. Epub 2017 Jul 31.

PMID:
31015599
15.

Photochemically Generated Thiyl Free Radicals Observed by X-ray Absorption Spectroscopy.

Sneeden EY, Hackett MJ, Cotelesage JJH, Prince RC, Barney M, Goto K, Block E, Pickering IJ, George GN.

J Am Chem Soc. 2017 Aug 23;139(33):11519-11526. doi: 10.1021/jacs.7b05116. Epub 2017 Aug 11.

PMID:
28750509
16.

Biological iron-sulfur storage in a thioferrate-protein nanoparticle.

Vaccaro BJ, Clarkson SM, Holden JF, Lee DW, Wu CH, Poole Ii FL, Cotelesage JJH, Hackett MJ, Mohebbi S, Sun J, Li H, Johnson MK, George GN, Adams MWW.

Nat Commun. 2017 Jul 20;8:16110. doi: 10.1038/ncomms16110.

17.

A Multimodal Spectroscopic Imaging Method To Characterize the Metal and Macromolecular Content of Proteinaceous Aggregates ("Amyloid Plaques").

Summers KL, Fimognari N, Hollings A, Kiernan M, Lam V, Tidy RJ, Paterson D, Tobin MJ, Takechi R, George GN, Pickering IJ, Mamo JC, Harris HH, Hackett MJ.

Biochemistry. 2017 Aug 15;56(32):4107-4116. doi: 10.1021/acs.biochem.7b00262. Epub 2017 Jul 18.

PMID:
28718623
18.

Parallel changes in cortical neuron biochemistry and motor function in protein-energy malnourished adult rats.

Alaverdashvili M, Hackett MJ, Caine S, Paterson PG.

Neuroimage. 2017 Apr 1;149:275-284. doi: 10.1016/j.neuroimage.2017.02.010. Epub 2017 Feb 4.

PMID:
28179168
19.

Rehabilitation Augments Hematoma Clearance and Attenuates Oxidative Injury and Ion Dyshomeostasis After Brain Hemorrhage.

Williamson MR, Dietrich K, Hackett MJ, Caine S, Nadeau CA, Aziz JR, Nichol H, Paterson PG, Colbourne F.

Stroke. 2017 Jan;48(1):195-203. doi: 10.1161/STROKEAHA.116.015404. Epub 2016 Nov 29.

PMID:
27899761
20.

Concurrent Glycogen and Lactate Imaging with FTIR Spectroscopy To Spatially Localize Metabolic Parameters of the Glial Response Following Brain Ischemia.

Hackett MJ, Sylvain NJ, Hou H, Caine S, Alaverdashvili M, Pushie MJ, Kelly ME.

Anal Chem. 2016 Nov 15;88(22):10949-10956. Epub 2016 Nov 3.

PMID:
27690391
21.

Imaging Taurine in the Central Nervous System Using Chemically Specific X-ray Fluorescence Imaging at the Sulfur K-Edge.

Hackett MJ, Paterson PG, Pickering IJ, George GN.

Anal Chem. 2016 Nov 15;88(22):10916-10924. Epub 2016 Nov 2.

22.

Mapping Alterations to the Endogenous Elemental Distribution within the Lateral Ventricles and Choroid Plexus in Brain Disorders Using X-Ray Fluorescence Imaging.

Lins BR, Pushie JM, Jones M, Howard DL, Howland JG, Hackett MJ.

PLoS One. 2016 Jun 28;11(6):e0158152. doi: 10.1371/journal.pone.0158152. eCollection 2016.

23.

Chemical Biology in the Embryo: In Situ Imaging of Sulfur Biochemistry in Normal and Proteoglycan-Deficient Cartilage Matrix.

Hackett MJ, George GN, Pickering IJ, Eames BF.

Biochemistry. 2016 May 3;55(17):2441-51. doi: 10.1021/acs.biochem.5b01136. Epub 2016 Apr 20.

PMID:
26985789
24.

A novel multi-modal platform to image molecular and elemental alterations in ischemic stroke.

Caine S, Hackett MJ, Hou H, Kumar S, Maley J, Ivanishvili Z, Suen B, Szmigielski A, Jiang Z, Sylvain NJ, Nichol H, Kelly ME.

Neurobiol Dis. 2016 Jul;91:132-42. doi: 10.1016/j.nbd.2016.03.006. Epub 2016 Mar 9.

PMID:
26969531
25.

Mechanisms of murine cerebral malaria: Multimodal imaging of altered cerebral metabolism and protein oxidation at hemorrhage sites.

Hackett MJ, Aitken JB, El-Assaad F, McQuillan JA, Carter EA, Ball HJ, Tobin MJ, Paterson D, de Jonge MD, Siegele R, Cohen DD, Vogt S, Grau GE, Hunt NH, Lay PA.

Sci Adv. 2015 Dec 18;1(11):e1500911. doi: 10.1126/sciadv.1500911. eCollection 2015 Dec.

26.

Distribution of selenium in zebrafish larvae after exposure to organic and inorganic selenium forms.

Dolgova NV, Hackett MJ, MacDonald TC, Nehzati S, James AK, Krone PH, George GN, Pickering IJ.

Metallomics. 2016 Mar;8(3):305-12. doi: 10.1039/c5mt00279f.

PMID:
26781816
27.

Novel bio-spectroscopic imaging reveals disturbed protein homeostasis and thiol redox with protein aggregation prior to hippocampal CA1 pyramidal neuron death induced by global brain ischemia in the rat.

Hackett MJ, Smith SE, Caine S, Nichol H, George GN, Pickering IJ, Paterson PG.

Free Radic Biol Med. 2015 Dec;89:806-18. doi: 10.1016/j.freeradbiomed.2015.08.029. Epub 2015 Oct 9.

28.

Interaction of mercury and selenium in the larval stage zebrafish vertebrate model.

MacDonald TC, Korbas M, James AK, Sylvain NJ, Hackett MJ, Nehzati S, Krone PH, George GN, Pickering IJ.

Metallomics. 2015 Aug;7(8):1247-55. doi: 10.1039/c5mt00145e. Epub 2015 Jul 16.

PMID:
26178186
29.

A new method to image heme-Fe, total Fe, and aggregated protein levels after intracerebral hemorrhage.

Hackett MJ, DeSouza M, Caine S, Bewer B, Nichol H, Paterson PG, Colbourne F.

ACS Chem Neurosci. 2015 May 20;6(5):761-70. doi: 10.1021/acschemneuro.5b00037. Epub 2015 Mar 2.

30.

In situ biospectroscopic investigation of rapid ischemic and postmortem induced biochemical alterations in the rat brain.

Hackett MJ, Britz CJ, Paterson PG, Nichol H, Pickering IJ, George GN.

ACS Chem Neurosci. 2015 Feb 18;6(2):226-38. doi: 10.1021/cn500157j. Epub 2014 Nov 13.

31.

Laminar-specific distribution of zinc: evidence for presence of layer IV in forelimb motor cortex in the rat.

Alaverdashvili M, Hackett MJ, Pickering IJ, Paterson PG.

Neuroimage. 2014 Dec;103:502-510. doi: 10.1016/j.neuroimage.2014.08.046. Epub 2014 Sep 2.

32.

Long-range chemical sensitivity in the sulfur K-edge X-ray absorption spectra of substituted thiophenes.

George GN, Hackett MJ, Sansone M, Gorbaty ML, Kelemen SR, Prince RC, Harris HH, Pickering IJ.

J Phys Chem A. 2014 Sep 11;118(36):7796-802. doi: 10.1021/jp505766f. Epub 2014 Aug 26.

33.

Elemental and chemically specific X-ray fluorescence imaging of biological systems.

Pushie MJ, Pickering IJ, Korbas M, Hackett MJ, George GN.

Chem Rev. 2014 Sep 10;114(17):8499-541. doi: 10.1021/cr4007297. Epub 2014 Aug 7. Review. No abstract available.

34.

pH-sensitive nanoformulated triptolide as a targeted therapeutic strategy for hepatocellular carcinoma.

Ling D, Xia H, Park W, Hackett MJ, Song C, Na K, Hui KM, Hyeon T.

ACS Nano. 2014 Aug 26;8(8):8027-39.

PMID:
25093274
35.

A general strategy for site-directed enzyme immobilization by using NiO nanoparticle decorated mesoporous silica.

Ling D, Gao L, Wang J, Shokouhimehr M, Liu J, Yu Y, Hackett MJ, So PK, Zheng B, Yao Z, Xia J, Hyeon T.

Chemistry. 2014 Jun 23;20(26):7916-21. doi: 10.1002/chem.201403071. Epub 2014 May 23.

PMID:
24861357
36.

Multifunctional tumor pH-sensitive self-assembled nanoparticles for bimodal imaging and treatment of resistant heterogeneous tumors.

Ling D, Park W, Park SJ, Lu Y, Kim KS, Hackett MJ, Kim BH, Yim H, Jeon YS, Na K, Hyeon T.

J Am Chem Soc. 2014 Apr 16;136(15):5647-55. doi: 10.1021/ja4108287. Epub 2014 Apr 1.

PMID:
24689550
37.

Cancer imaging: Lighting up tumours.

Ling D, Hackett MJ, Hyeon T.

Nat Mater. 2014 Feb;13(2):122-4. doi: 10.1038/nmat3860. No abstract available.

PMID:
24452354
38.

Subcellular biochemical investigation of purkinje neurons using synchrotron radiation fourier transform infrared spectroscopic imaging with a focal plane array detector.

Hackett MJ, Borondics F, Brown D, Hirschmugl C, Smith SE, Paterson PG, Nichol H, Pickering IJ, George GN.

ACS Chem Neurosci. 2013 Jul 17;4(7):1071-80. doi: 10.1021/cn4000346. Epub 2013 May 20.

39.

FTIR imaging of brain tissue reveals crystalline creatine deposits are an ex vivo marker of localized ischemia during murine cerebral malaria: general implications for disease neurochemistry.

Hackett MJ, Lee J, El-Assaad F, McQuillan JA, Carter EA, Grau GE, Hunt NH, Lay PA.

ACS Chem Neurosci. 2012 Dec 19;3(12):1017-24. doi: 10.1021/cn300093g. Epub 2012 Sep 11.

40.

X-ray-induced photo-chemistry and X-ray absorption spectroscopy of biological samples.

George GN, Pickering IJ, Pushie MJ, Nienaber K, Hackett MJ, Ascone I, Hedman B, Hodgson KO, Aitken JB, Levina A, Glover C, Lay PA.

J Synchrotron Radiat. 2012 Nov;19(Pt 6):875-86. doi: 10.1107/S090904951203943X. Epub 2012 Oct 18.

41.

Fatty acids as therapeutic auxiliaries for oral and parenteral formulations.

Hackett MJ, Zaro JL, Shen WC, Guley PC, Cho MJ.

Adv Drug Deliv Rev. 2013 Oct;65(10):1331-9. doi: 10.1016/j.addr.2012.07.012. Epub 2012 Aug 17. Review.

42.

X-ray absorption spectroscopy at the sulfur K-edge: a new tool to investigate the biochemical mechanisms of neurodegeneration.

Hackett MJ, Smith SE, Paterson PG, Nichol H, Pickering IJ, George GN.

ACS Chem Neurosci. 2012 Mar 21;3(3):178-85. doi: 10.1021/cn200097s. Epub 2012 Jan 2.

43.

A dicarboxylic fatty acid derivative of paclitaxel for albumin-assisted drug delivery.

Hackett MJ, Joolakanti S, Hartranft ME, Guley PC, Cho MJ.

J Pharm Sci. 2012 Sep;101(9):3292-304. doi: 10.1002/jps.23213. Epub 2012 Jun 6.

44.

Prolonged therapeutic hypothermia does not adversely impact neuroplasticity after global ischemia in rats.

Silasi G, Klahr AC, Hackett MJ, Auriat AM, Nichol H, Colbourne F.

J Cereb Blood Flow Metab. 2012 Aug;32(8):1525-34. doi: 10.1038/jcbfm.2012.38. Epub 2012 Mar 21.

45.

Expanding the clinical and genetic spectrum of human CD40L deficiency: the occurrence of paracoccidioidomycosis and other unusual infections in Brazilian patients.

Cabral-Marques O, Schimke LF, Pereira PV, Falcai A, de Oliveira JB, Hackett MJ, Errante PR, Weber CW, Ferreira JF, Kuntze G, Rosário-Filho NA, Ochs HD, Torgerson TR, Carvalho BT, Condino-Neto A.

J Clin Immunol. 2012 Apr;32(2):212-20. doi: 10.1007/s10875-011-9623-6. Epub 2011 Dec 23.

PMID:
22193914
46.

Dendritic cells from X-linked hyper-IgM patients present impaired responses to Candida albicans and Paracoccidioides brasiliensis.

Cabral-Marques O, Arslanian C, Ramos RN, Morato M, Schimke L, Soeiro Pereira PV, Jancar S, Ferreira JF, Weber CW, Kuntze G, Rosario-Filho NA, Costa Carvalho BT, Bergami-Santos PC, Hackett MJ, Ochs HD, Torgerson TR, Barbuto JA, Condino-Neto A.

J Allergy Clin Immunol. 2012 Mar;129(3):778-86. doi: 10.1016/j.jaci.2011.10.026. Epub 2011 Dec 10.

PMID:
22154528
47.

Chemical alterations to murine brain tissue induced by formalin fixation: implications for biospectroscopic imaging and mapping studies of disease pathogenesis.

Hackett MJ, McQuillan JA, El-Assaad F, Aitken JB, Levina A, Cohen DD, Siegele R, Carter EA, Grau GE, Hunt NH, Lay PA.

Analyst. 2011 Jul 21;136(14):2941-52. doi: 10.1039/c0an00269k. Epub 2011 May 31.

PMID:
21629894
48.

Tumor-targeted delivery of siRNA by self-assembled nanoparticles.

Li SD, Chen YC, Hackett MJ, Huang L.

Mol Ther. 2008 Jan;16(1):163-9. Epub 2007 Oct 9.

49.

Cream for topical treatment of burns.

Hackett MJ, Summers F.

Lancet. 1970 Apr 18;1(7651):844. No abstract available.

PMID:
4191470

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